|
US20040219565A1
(en)
|
2002-10-21 |
2004-11-04 |
Sakari Kauppinen |
Oligonucleotides useful for detecting and analyzing nucleic acids of interest
|
|
US8192937B2
(en)
|
2004-04-07 |
2012-06-05 |
Exiqon A/S |
Methods for quantification of microRNAs and small interfering RNAs
|
|
WO2006069584A2
(en)
*
|
2004-12-29 |
2006-07-06 |
Exiqon A/S |
NOVEL OLIGONUCLEOTIDE COMPOSITIONS AND PROBE SEQUENCES USEFUL FOR DETECTION AND ANALYSIS OF microRNAs AND THEIR TARGET mRNAs
|
|
US8071306B2
(en)
|
2005-01-25 |
2011-12-06 |
Merck Sharp & Dohme Corp. |
Methods for quantitating small RNA molecules
|
|
US20090123912A1
(en)
*
|
2005-01-25 |
2009-05-14 |
Rosetta Inpharmatics Llc |
Methods for quantitating small RNA molecules
|
|
WO2006130761A1
(en)
*
|
2005-05-31 |
2006-12-07 |
Applera Corporation |
Linear amplification of short nucleic acids
|
|
JP2007082436A
(ja)
*
|
2005-09-20 |
2007-04-05 |
Bioinformatics Institute For Global Good Inc |
機能性RNAが制御するターゲットmRNAの予測・同定方法及びその利用方法
|
|
EP1966390A1
(en)
*
|
2005-12-29 |
2008-09-10 |
Exiqon A/S |
Detection of tissue origin of cancer
|
|
US7955848B2
(en)
|
2006-04-03 |
2011-06-07 |
Trustees Of Dartmouth College |
MicroRNA biomarkers for human breast and lung cancer
|
|
US20100004320A1
(en)
|
2006-04-03 |
2010-01-07 |
Santaris Pharma A/S |
Pharmaceutical Composition
|
|
US8207325B2
(en)
|
2006-04-03 |
2012-06-26 |
Univ. of Copenhagen |
MicroRNA biomarkers for human breast and lung cancer
|
|
EA201100813A1
(ru)
|
2006-04-03 |
2012-06-29 |
Сантарис Фарма А/С |
Фармацевтическая композиция
|
|
US8580494B2
(en)
*
|
2006-08-25 |
2013-11-12 |
Research Foundation For Mental Hygiene, Inc. |
Methods and compositions for amplification and detection of MicroRNAs
|
|
WO2008040355A2
(en)
*
|
2006-10-06 |
2008-04-10 |
Exiqon A/S |
Novel methods for quantification of micrornas and small interfering rnas
|
|
WO2008046911A2
(en)
|
2006-10-20 |
2008-04-24 |
Exiqon A/S |
Novel human micrornas associated with cancer
|
|
US8188255B2
(en)
|
2006-10-20 |
2012-05-29 |
Exiqon A/S |
Human microRNAs associated with cancer
|
|
EP1914317A1
(en)
*
|
2006-10-21 |
2008-04-23 |
Biolytix AG |
A method for qualitative and quantitative detection of short nucleic acid sequences of about 8 to 50 nucleotides in length
|
|
US7645578B2
(en)
|
2006-10-31 |
2010-01-12 |
Agilent Technologies, Inc. |
Cleavage of RNA at redundant sites
|
|
US8580756B2
(en)
|
2007-03-22 |
2013-11-12 |
Santaris Pharma A/S |
Short oligomer antagonist compounds for the modulation of target mRNA
|
|
EP2126079A1
(en)
|
2007-03-22 |
2009-12-02 |
Santaris Pharma A/S |
Rna antagonist compounds for the inhibition of apo-b100 expression
|
|
EP1978104A1
(en)
*
|
2007-04-03 |
2008-10-08 |
Freie Universität Berlin |
A method for the quantitative analysis of RNA molecules in a sample
|
|
EA019939B1
(ru)
|
2007-10-04 |
2014-07-30 |
Сантарис Фарма А/С |
МОДИФИЦИРОВАННЫЙ ОЛИГОМЕР ДЛЯ УМЕНЬШЕНИЯ КОЛИЧЕСТВА микроРНК В КЛЕТКЕ
|
|
ES2526925T3
(es)
*
|
2007-10-09 |
2015-01-16 |
Igor Vassily Kutyavin |
Métodos para la detección mejorada de moléculas pequeñas de RNA
|
|
MX2010005166A
(es)
|
2007-11-09 |
2010-10-07 |
Univ Texas |
Micro arn de la familia mir-15 que modulan la sobrevivencia de cardiomiocitos y reparacion cardiaca.
|
|
US20110033858A1
(en)
*
|
2008-02-04 |
2011-02-10 |
Genecare Research Institute Co., Ltd. |
siRNA DETECTION METHOD
|
|
US8361980B2
(en)
|
2008-03-07 |
2013-01-29 |
Santaris Pharma A/S |
Pharmaceutical compositions for treatment of microRNA related diseases
|
|
WO2010012667A1
(en)
|
2008-08-01 |
2010-02-04 |
Santaris Pharma A/S |
Micro-rna mediated modulation of colony stimulating factors
|
|
US20100240049A1
(en)
|
2009-01-16 |
2010-09-23 |
Cepheid |
Methods of Detecting Cervical Cancer
|
|
SG173042A1
(en)
*
|
2009-01-19 |
2011-08-29 |
Sistemic Scotland Ltd |
Methods employing non-coding rna expression assays
|
|
WO2010088668A2
(en)
|
2009-02-02 |
2010-08-05 |
Cepheid |
Methods of detecting sepsis
|
|
SG173506A1
(en)
*
|
2009-02-02 |
2011-09-29 |
Exiqon As |
Method for quantification of small rna species
|
|
US8962253B2
(en)
|
2009-04-13 |
2015-02-24 |
Somagenics Inc. |
Methods and compositions for detection of small RNAs
|
|
ES2599979T3
(es)
|
2009-04-24 |
2017-02-06 |
Roche Innovation Center Copenhagen A/S |
Composiciones farmacéuticas para el tratamiento de pacientes de VHC que no responden al interferón
|
|
EP2456870A1
(en)
|
2009-07-21 |
2012-05-30 |
Santaris Pharma A/S |
Antisense oligomers targeting pcsk9
|
|
KR101822609B1
(ko)
*
|
2010-06-24 |
2018-01-26 |
주식회사 파나진 |
Pna 기반의 실시간 pcr 클램핑을 이용한 마이크로rna 발현양상의 분석 방법 및 키트
|
|
US9200314B2
(en)
*
|
2010-07-21 |
2015-12-01 |
Takara Bio Inc. |
Synthetic siRNA detection method
|
|
CN103703142A
(zh)
|
2011-01-26 |
2014-04-02 |
西菲伊德公司 |
检测肺癌的方法
|
|
CN102154505B
(zh)
*
|
2011-04-20 |
2013-03-20 |
苟德明 |
一种检测miRNA的方法及引物及其应用
|
|
US9816130B2
(en)
|
2011-12-22 |
2017-11-14 |
Somagenics, Inc. |
Methods of constructing small RNA libraries and their use for expression profiling of target RNAs
|
|
EP2814984A4
(en)
*
|
2012-02-14 |
2015-07-29 |
Univ Johns Hopkins |
MIRNA ANALYSIS PROCEDURE
|
|
US9163235B2
(en)
|
2012-06-21 |
2015-10-20 |
MiRagen Therapeutics, Inc. |
Inhibitors of the miR-15 family of micro-RNAs
|
|
ES2749463T3
(es)
|
2012-11-02 |
2020-03-20 |
Life Technologies Corp |
Captura, detección y cuantificación de ARN pequeño
|
|
WO2014113614A1
(en)
*
|
2013-01-16 |
2014-07-24 |
The Regents Of The University Of California |
Label free molecular detection methods, systems and devices
|
|
WO2014113598A2
(en)
|
2013-01-16 |
2014-07-24 |
The Regents Of The University Of California |
Microfluidic devices to extract, concentrate and isolate molecules
|
|
WO2014153260A1
(en)
*
|
2013-03-14 |
2014-09-25 |
Arnold Lyle J |
Methods for amplification of nucleic acids on solid support
|
|
CN103218543B
(zh)
*
|
2013-03-27 |
2016-04-13 |
中国科学院计算技术研究所 |
一种区分蛋白编码基因和非编码基因的方法及系统
|
|
SG10201908122XA
(en)
|
2013-06-27 |
2019-10-30 |
Roche Innovation Ct Copenhagen As |
Antisense oligomers and conjugates targeting pcsk9
|
|
CN104109708B
(zh)
*
|
2013-12-31 |
2015-05-13 |
厦门成坤生物技术有限公司 |
一种直接测定生物样品中未经分离的小核酸的方法及检测试剂盒
|
|
WO2015169947A1
(en)
|
2014-05-09 |
2015-11-12 |
Lifecodexx Ag |
Detection of dna that originates from a specific cell-type and related methods
|
|
EP2942400A1
(en)
|
2014-05-09 |
2015-11-11 |
Lifecodexx AG |
Multiplex detection of DNA that originates from a specific cell-type
|
|
ES2904909T3
(es)
*
|
2014-10-08 |
2022-04-06 |
Univ Cornell |
Método para la identificación y la cuantificación relativa de cambios en la expresión de secuencias de ácidos nucleicos, en variantes de corte y empalme, en la translocación, en el número de copias o en la metilación utilizando reacciones combinadas de nucleasa, de ligadura y de polimerasa con prevención de arrastre
|
|
CN104598775B
(zh)
*
|
2014-12-31 |
2018-10-16 |
北京邮电大学 |
一种rna编辑事件识别方法
|
|
JP6383015B2
(ja)
|
2015-01-22 |
2018-08-29 |
アークレイ株式会社 |
ターゲット分析チップおよびターゲット分析方法
|
|
CN104673901B
(zh)
*
|
2015-02-06 |
2018-05-11 |
中国医学科学院基础医学研究所 |
用于检测靶核酸的用途和试剂盒
|
|
US10563250B2
(en)
|
2015-03-13 |
2020-02-18 |
Life Technologies Corporation |
Methods, compositions and kits for small RNA capture, detection and quantification
|
|
CN104975078A
(zh)
*
|
2015-05-18 |
2015-10-14 |
上海市农业科学院 |
一种检测转基因植物中靶标siRNA池的方法
|
|
TWI676679B
(zh)
*
|
2015-06-02 |
2019-11-11 |
奎克生技光電股份有限公司 |
核苷酸序列、通用反向引子、通用反轉錄引子、引子設計方法及miRNA檢測方法
|
|
HUE050491T2
(hu)
|
2015-11-10 |
2020-12-28 |
Eurofins Lifecodexx Gmbh |
Magzati kromoszomális aneuploidiák kimutatása olyan DNS régiókat alkalmazva, amelyek különbözõképpen vannak metilezve a magzat és a terhes nõstény között
|
|
US11014957B2
(en)
|
2015-12-21 |
2021-05-25 |
Realseq Biosciences, Inc. |
Methods of library construction for polynucleotide sequencing
|
|
JP6577660B2
(ja)
|
2016-03-18 |
2019-09-18 |
株式会社東芝 |
試料中の複数種類の短鎖核酸の検出方法、組み合わせ分析キットおよび分析キット供給管理方法
|
|
CZ307055B6
(cs)
*
|
2016-04-29 |
2017-12-20 |
Ústav molekulární genetiky AV ČR, v.v.i. |
Způsob detekce specifických mikroRNA pomocí templátové DNA a molekula templátové DNA pro použití při tomto způsobu
|
|
WO2019011875A1
(en)
*
|
2017-07-11 |
2019-01-17 |
Qiagen Gmbh |
QUANTIFICATION OF ANTISENSE OLIGONUCLEOTIDES (ASOS)
|
|
CN113195734B
(zh)
*
|
2018-12-20 |
2024-12-24 |
豪夫迈·罗氏有限公司 |
通过固相分子成像检测靶核酸
|
|
WO2020239822A1
(en)
*
|
2019-05-27 |
2020-12-03 |
The European Molecular Biology Laboratory |
Nucleic acid construct binding to influenza polymerase pb1 rna synthesis active site
|
|
EP3901286A1
(en)
*
|
2020-04-24 |
2021-10-27 |
Mirnax Biosens, S.L. |
Bivalent reverse primer
|
|
WO2021089643A1
(en)
*
|
2019-11-04 |
2021-05-14 |
Mirnax Biosens, S.L. |
Bivalent reverse primer
|
|
CN111665351B
(zh)
*
|
2020-06-20 |
2021-12-03 |
江南大学 |
一种快速、特异性测定rna含量的方法
|
|
CN113322523B
(zh)
*
|
2021-06-17 |
2024-03-19 |
翌圣生物科技(上海)股份有限公司 |
Rna快速建库方法及其应用
|
|
CN116200492B
(zh)
*
|
2022-11-08 |
2025-04-01 |
浙江大学 |
一种基于探针锚定双链的小核酸检测试剂盒及其应用
|