CA2551474A1 - Medical lipolysis of fat accumulations - Google Patents

Medical lipolysis of fat accumulations Download PDF

Info

Publication number
CA2551474A1
CA2551474A1 CA002551474A CA2551474A CA2551474A1 CA 2551474 A1 CA2551474 A1 CA 2551474A1 CA 002551474 A CA002551474 A CA 002551474A CA 2551474 A CA2551474 A CA 2551474A CA 2551474 A1 CA2551474 A1 CA 2551474A1
Authority
CA
Canada
Prior art keywords
weight
fat
acid
phospholipid
employed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002551474A
Other languages
English (en)
French (fr)
Inventor
Peter Boderke
Matthias Gossel
Walter Kamm
Karl-Heinz Nietsch
Rainer Pooth
Juergen Sandow
Joerg Hager
Gerhard Sattler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Peter Boderke
Matthias Gossel
Walter Kamm
Karl-Heinz Nietsch
Rainer Pooth
Juergen Sandow
Joerg Hager
Gerhard Sattler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh, Peter Boderke, Matthias Gossel, Walter Kamm, Karl-Heinz Nietsch, Rainer Pooth, Juergen Sandow, Joerg Hager, Gerhard Sattler filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of CA2551474A1 publication Critical patent/CA2551474A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/413—Gall bladder; Bile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002551474A 2003-12-22 2004-12-11 Medical lipolysis of fat accumulations Abandoned CA2551474A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10361067.7 2003-12-22
DE10361067A DE10361067A1 (de) 2003-12-22 2003-12-22 Medikamentöse Lipolyse von Fettansammlungen
PCT/EP2004/014134 WO2005063169A2 (de) 2003-12-22 2004-12-11 Medikamentöse lipolyse von fettansammlungen

Publications (1)

Publication Number Publication Date
CA2551474A1 true CA2551474A1 (en) 2005-07-14

Family

ID=34673059

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002551474A Abandoned CA2551474A1 (en) 2003-12-22 2004-12-11 Medical lipolysis of fat accumulations

Country Status (11)

Country Link
EP (1) EP1699490A2 (pt)
JP (1) JP2007515439A (pt)
KR (1) KR20060121238A (pt)
CN (1) CN1897974A (pt)
AU (1) AU2004308072A1 (pt)
BR (1) BRPI0417932A (pt)
CA (1) CA2551474A1 (pt)
DE (1) DE10361067A1 (pt)
IL (1) IL176026A0 (pt)
MX (1) MXPA06006645A (pt)
WO (1) WO2005063169A2 (pt)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8298556B2 (en) 2004-05-19 2012-10-30 The Regents Of The University Of California Methods and related compositions for the non-surgical removal of fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
US8846066B2 (en) 2004-05-19 2014-09-30 The Regents Of The University Of California Methods and related compositions for reduction of fat and skin tightening
US9186364B2 (en) 2009-03-03 2015-11-17 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US11298314B2 (en) 2017-04-21 2022-04-12 Ami Pharm Co., Ltd. Injectable composition for localized fat reduction without pain, edema, and side effects, and method for preparing same
US11344561B2 (en) 2011-02-18 2022-05-31 Allergan Sales, Llc Treatment of submental fat

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
PT1845938T (pt) * 2005-02-08 2019-07-11 Univ California Métodos e composições relacionadas para redução da gordura e para refirmar a pele
DE102007015701A1 (de) 2007-03-19 2008-09-25 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung
FR2937554B1 (fr) * 2008-10-27 2010-11-12 Yves Crassas Solutions salines aqueuses pour la destruction de tissus graisseux
JP6006940B2 (ja) * 2009-03-02 2016-10-12 ヘクセル，ドリス 医学的美容脂肪萎縮方法
SG178559A1 (en) 2009-08-25 2012-03-29 Medrx Co Ltd Transdermal composition of phosphatidylcholine and method for producing same
DE102010028365A1 (de) 2010-04-29 2011-11-03 Lichtblick Gmbh Verwendung einer Phospholipid enthaltenden Zusammensetzung zur Entfernung von subkutanen Fettansammlungen
CN108619089A (zh) * 2011-08-23 2018-10-09 凯瑟拉生物制药有限公司 脱氧胆酸和其盐的制剂
RU2016141131A (ru) * 2014-03-21 2018-04-23 Нестек С.А. Введение витамина b2 матери для профилактики повышенной тучности, избыточного веса или ожирения у потомства
KR102093872B1 (ko) * 2017-07-03 2020-03-27 진호성 지방제거용 주사제 조성물 및 이의 제조방법
JP6356329B2 (ja) * 2017-09-27 2018-07-11 キテラ バイオファーマシューティカルズ，インコーポレイテッド デオキシコール酸およびその塩類の製剤
KR101865562B1 (ko) * 2017-11-03 2018-06-08 주식회사 펜믹스 포스포콜린 유도체를 포함하는 지방분해 조성물
KR20190095833A (ko) * 2018-02-07 2019-08-16 이기택 고통 및 부작용이 없는 국소지방 감소용 포스파티딜콜린 비포함 주사제 조성물
CN110302082A (zh) * 2018-03-27 2019-10-08 上海同柏生物科技有限公司 用于减少身体脂肪沉积的技术及组合物制剂与应用
CN109674696A (zh) * 2018-03-27 2019-04-26 上海同柏生物科技有限公司 一种用于腹部脂肪降解技术及其制剂与应用
EP4159240A1 (en) 2020-06-01 2023-04-05 Cosmed Pharmaceutical Co., Ltd. Beauty microneedle array
JP2022020578A (ja) * 2020-07-20 2022-02-01 コスメディ製薬株式会社 美容用外用剤及び化粧料
KR102513115B1 (ko) * 2020-12-18 2023-03-22 주식회사 레시텍 리토콜릭산을 포함하는 국소지방 감소용 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10349979B4 (de) * 2003-10-24 2006-05-18 Sanofi-Aventis Deutschland Gmbh Medikamentöse gezielte lokale Lipolyse

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8298556B2 (en) 2004-05-19 2012-10-30 The Regents Of The University Of California Methods and related compositions for the non-surgical removal of fat
US10058561B2 (en) 2004-05-19 2018-08-28 The Regents Of The University Of California Methods and related compositions for reduction of fat and skin tightening
US8846066B2 (en) 2004-05-19 2014-09-30 The Regents Of The University Of California Methods and related compositions for reduction of fat and skin tightening
US9186364B2 (en) 2009-03-03 2015-11-17 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US9724356B2 (en) 2009-03-03 2017-08-08 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US10071105B2 (en) 2009-03-03 2018-09-11 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US10500214B2 (en) 2009-03-03 2019-12-10 Allergan Sales, Llc Formulations of deoxycholic acid and salts thereof
US11179404B2 (en) 2009-03-03 2021-11-23 Allergan Sales, Llc Formulations of deoxycholic acid and salts thereof
US11344561B2 (en) 2011-02-18 2022-05-31 Allergan Sales, Llc Treatment of submental fat
US9737549B2 (en) 2011-04-05 2017-08-22 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
US10946030B2 (en) 2011-04-05 2021-03-16 Allergan Sales, Llc Formulations of deoxycholic acid and salts thereof
US11298314B2 (en) 2017-04-21 2022-04-12 Ami Pharm Co., Ltd. Injectable composition for localized fat reduction without pain, edema, and side effects, and method for preparing same

Also Published As

Publication number Publication date
CN1897974A (zh) 2007-01-17
IL176026A0 (en) 2006-10-05
EP1699490A2 (de) 2006-09-13
WO2005063169A3 (de) 2006-05-04
WO2005063169A2 (de) 2005-07-14
DE10361067A1 (de) 2005-07-14
KR20060121238A (ko) 2006-11-28
MXPA06006645A (es) 2006-08-31
BRPI0417932A (pt) 2007-04-17
JP2007515439A (ja) 2007-06-14
AU2004308072A1 (en) 2005-07-14

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Legal Events

Date Code Title Description
FZDE Discontinued