CA2526556C - Stable radiopharmaceutical compositions and methods for their preparation - Google Patents

Stable radiopharmaceutical compositions and methods for their preparation Download PDF

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Publication number
CA2526556C
CA2526556C CA2526556A CA2526556A CA2526556C CA 2526556 C CA2526556 C CA 2526556C CA 2526556 A CA2526556 A CA 2526556A CA 2526556 A CA2526556 A CA 2526556A CA 2526556 C CA2526556 C CA 2526556C
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CA
Canada
Prior art keywords
oxidation state
compound containing
water
acid
radiopharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CA2526556A
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English (en)
French (fr)
Other versions
CA2526556A1 (en
Inventor
Jianqing Chen
Karen E. Linder
Edmund R. Marinelli
Edmund Metcalfe
Adrian Nunn
Rolf E. Swenson
Michael Tweedle
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Bracco Imaging SpA
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Bracco Imaging SpA
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Priority to CA2783275A priority Critical patent/CA2783275A1/en
Publication of CA2526556A1 publication Critical patent/CA2526556A1/en
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Publication of CA2526556C publication Critical patent/CA2526556C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2526556A 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for their preparation Expired - Fee Related CA2526556C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2783275A CA2783275A1 (en) 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for their preparation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48985003P 2003-07-24 2003-07-24
US60/489,850 2003-07-24
PCT/US2004/023930 WO2005009393A2 (en) 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2783275A Division CA2783275A1 (en) 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for their preparation

Publications (2)

Publication Number Publication Date
CA2526556A1 CA2526556A1 (en) 2005-02-03
CA2526556C true CA2526556C (en) 2012-09-25

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CA2783275A Abandoned CA2783275A1 (en) 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for their preparation
CA2526556A Expired - Fee Related CA2526556C (en) 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2783275A Abandoned CA2783275A1 (en) 2003-07-24 2004-07-23 Stable radiopharmaceutical compositions and methods for their preparation

Country Status (13)

Country Link
US (3) US20070269375A1 (ru)
EP (1) EP1654005A4 (ru)
JP (2) JP5139678B2 (ru)
KR (1) KR101106533B1 (ru)
CN (1) CN100418585C (ru)
AU (1) AU2004259028C1 (ru)
BR (1) BRPI0412824A (ru)
CA (2) CA2783275A1 (ru)
IL (1) IL172059A0 (ru)
RU (1) RU2006105644A (ru)
SG (2) SG177216A1 (ru)
WO (1) WO2005009393A2 (ru)
ZA (1) ZA200509666B (ru)

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RU2006105644A (ru) 2006-08-10
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US20070269375A1 (en) 2007-11-22
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US20110206606A1 (en) 2011-08-25
KR20060064049A (ko) 2006-06-12
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EP1654005A4 (en) 2011-06-15
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