FR2891830B1 - Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale - Google Patents
Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicaleInfo
- Publication number
- FR2891830B1 FR2891830B1 FR0510289A FR0510289A FR2891830B1 FR 2891830 B1 FR2891830 B1 FR 2891830B1 FR 0510289 A FR0510289 A FR 0510289A FR 0510289 A FR0510289 A FR 0510289A FR 2891830 B1 FR2891830 B1 FR 2891830B1
- Authority
- FR
- France
- Prior art keywords
- medical imaging
- metal complexes
- aminoalcohol compounds
- short
- short aminoalcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001414 amino alcohols Chemical class 0.000 title 1
- 238000002059 diagnostic imaging Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/03—Monoamines
- C07C211/05—Mono-, di- or tri-ethylamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Priority Applications (28)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0510289A FR2891830B1 (fr) | 2005-10-07 | 2005-10-07 | Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale |
DK06807100.0T DK1931673T3 (da) | 2005-10-07 | 2006-10-09 | Forbindelser, der omfatter korte aminoalkoholkæder og metalkomplekser, til medicinsk billeddannelse |
CN201310087412.9A CN103224495B (zh) | 2005-10-07 | 2006-10-09 | 含有短氨基醇链的化合物和用于医学成像的金属络合物 |
EP06807097.8A EP1940841B9 (fr) | 2005-10-07 | 2006-10-09 | Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium |
JP2008534029A JP5317270B2 (ja) | 2005-10-07 | 2006-10-09 | 医用画像のための短いアミノアルコール鎖および金属錯体を含む化合物 |
CA2625196A CA2625196C (fr) | 2005-10-07 | 2006-10-09 | Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium |
KR1020147009046A KR101440761B1 (ko) | 2005-10-07 | 2006-10-09 | 의학 영상용 짧은 아미노알코올 사슬과 금속착물을 포함하는 화합물 |
CA2625207A CA2625207C (fr) | 2005-10-07 | 2006-10-09 | Composes comprenant des chaines aminoalcool courtes et des complexes metalliques en imagerie medicale |
ES06807100T ES2390092T3 (es) | 2005-10-07 | 2006-10-09 | Compuestos que comprenden cadenas de aminoalcohol cortas y complejos metálicos para la obtención de imágenes médicas |
EP12153144.6A EP2457914B1 (fr) | 2005-10-07 | 2006-10-09 | Composés comprenant des chaînes d'amino-alcool courtes et des complexes métalliques pour l'imagerie médicale |
PCT/EP2006/067211 WO2007042504A2 (fr) | 2005-10-07 | 2006-10-09 | Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium |
PCT/EP2006/067214 WO2007042506A1 (fr) | 2005-10-07 | 2006-10-09 | Composés comprenant des chaînes aminoalcool courtes et des complexes métalliques en imagerie médicale |
ES12153144.6T ES2519369T3 (es) | 2005-10-07 | 2006-10-09 | Compuestos que comprenden cadenas de aminoalcohol cortas y complejos metálicos para la obtención de imágenes médicas |
PL06807100T PL1931673T3 (pl) | 2005-10-07 | 2006-10-09 | Związki zawierające krótkie łańcuchy aminoalkoholowe i kompleksy metali do obrazowania medycznego |
PT06807100T PT1931673E (pt) | 2005-10-07 | 2006-10-09 | Compostos que compreendem cadeias de aminoálcoois e complexos metálicos para imagiologia médica |
EP06807100A EP1931673B1 (fr) | 2005-10-07 | 2006-10-09 | Composés comprenant des chaînes aminoalcool courtes et des complexes métalliques en imagerie médicale |
KR1020087010991A KR20080080495A (ko) | 2005-10-07 | 2006-10-09 | 의학 영상용 짧은 아미노알코올 사슬과 금속착물을포함하는 화합물 |
BRPI0617151A BRPI0617151B8 (pt) | 2005-10-07 | 2006-10-09 | composto, multímero, composto vetorizado, complexo do referido composto, bem como composições farmacêutica, farmacêutica lipídica e de diagnóstico para imagiologia por ressonância magnética e processo para a preparação de um complexo metálico |
JP2008534028A JP5368099B2 (ja) | 2005-10-07 | 2006-10-09 | ガリウムと錯体形成することが可能なシグナル部分にカップリングされた、生物学的標的の認識のための部分を含んでなる化合物 |
US12/083,092 US8114863B2 (en) | 2005-10-07 | 2006-10-09 | Compounds comprising short aminoalcohol chains and metal complexes for medical imaging |
CN2006800416152A CN101305006B (zh) | 2005-10-07 | 2006-10-09 | 含有短氨基醇链的化合物和用于医学成像的金属络合物 |
US12/083,269 US8926945B2 (en) | 2005-10-07 | 2006-10-09 | Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium |
US13/205,352 US8986650B2 (en) | 2005-10-07 | 2011-08-08 | Complex folate-NOTA-Ga68 |
JP2013105720A JP5731572B2 (ja) | 2005-10-07 | 2013-05-20 | 医用画像のための短いアミノアルコール鎖および金属錯体を含む化合物 |
JP2013107700A JP5706926B2 (ja) | 2005-10-07 | 2013-05-22 | ガリウムと錯体形成することが可能なシグナル部分にカップリングされた、生物学的標的の認識のための部分を含んでなる化合物 |
FR24C1006C FR24C1006I1 (fr) | 2005-10-07 | 2024-02-19 | Composes comprenant des chaines aminoalcool courtes et des complexes metalliques en imagerie medicale |
NL301259C NL301259I2 (nl) | 2005-10-07 | 2024-02-21 | Gadopiclenol |
FIC20240003C FIC20240003I1 (fi) | 2005-10-07 | 2024-02-26 | Gadopiklenoli |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0510289A FR2891830B1 (fr) | 2005-10-07 | 2005-10-07 | Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2891830A1 FR2891830A1 (fr) | 2007-04-13 |
FR2891830B1 true FR2891830B1 (fr) | 2011-06-24 |
Family
ID=36636179
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0510289A Active FR2891830B1 (fr) | 2005-10-07 | 2005-10-07 | Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale |
FR24C1006C Active FR24C1006I1 (fr) | 2005-10-07 | 2024-02-19 | Composes comprenant des chaines aminoalcool courtes et des complexes metalliques en imagerie medicale |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR24C1006C Active FR24C1006I1 (fr) | 2005-10-07 | 2024-02-19 | Composes comprenant des chaines aminoalcool courtes et des complexes metalliques en imagerie medicale |
Country Status (15)
Country | Link |
---|---|
US (1) | US8114863B2 (fr) |
EP (2) | EP2457914B1 (fr) |
JP (2) | JP5317270B2 (fr) |
KR (2) | KR20080080495A (fr) |
CN (2) | CN103224495B (fr) |
BR (1) | BRPI0617151B8 (fr) |
CA (1) | CA2625207C (fr) |
DK (1) | DK1931673T3 (fr) |
ES (2) | ES2390092T3 (fr) |
FI (1) | FIC20240003I1 (fr) |
FR (2) | FR2891830B1 (fr) |
NL (1) | NL301259I2 (fr) |
PL (1) | PL1931673T3 (fr) |
PT (1) | PT1931673E (fr) |
WO (1) | WO2007042506A1 (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2891830B1 (fr) * | 2005-10-07 | 2011-06-24 | Guerbet Sa | Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale |
FR2914303A1 (fr) * | 2007-03-28 | 2008-10-03 | Guerbet Sa | Composes pour le diagnostic de l'apoptose. |
US8378134B2 (en) | 2009-09-30 | 2013-02-19 | General Electric Company | Hydroxylated contrast enhancement agents |
US20110077396A1 (en) * | 2009-09-30 | 2011-03-31 | General Electric Company | Intermediates for hydroxylated contrast enhancement agents |
FR2968999B1 (fr) | 2010-12-20 | 2013-01-04 | Guerbet Sa | Nanoemulsion de chelate pour irm |
CA2839647C (fr) * | 2011-08-17 | 2022-08-16 | Merck & Cie | Conjugues avec des folates d'entites de liaison de l'albumine |
FR2980364B1 (fr) | 2011-09-26 | 2018-08-31 | Guerbet | Nanoemulsions et leur utilisation comme agents de contraste |
FR3001154B1 (fr) | 2013-01-23 | 2015-06-26 | Guerbet Sa | Magneto-emulsion vectorisee |
BR112015026473B1 (pt) * | 2013-04-26 | 2020-12-01 | Guerbet | composições farmacêuticas líquidas e processo de preparação das mesmas e meio de contraste para imagiologia médica |
CN103467504B (zh) * | 2013-09-23 | 2015-06-24 | 武汉工程大学 | 18f-氟标记卟啉-异氮杂茚自由基配合物及合成方法 |
CN104485193B (zh) * | 2014-12-29 | 2016-11-02 | 广西师范大学 | 一种以酰腙类希夫碱为配体构筑的磁性材料及其制备方法 |
EP3101012A1 (fr) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | Nouveaux composés de chélate de gadolinium pour une utilisation dans l'imagerie par résonance magnétique |
FR3039767B1 (fr) | 2015-08-04 | 2017-09-08 | Guerbet Sa | Composition destinee a vectoriser un agent anticancereux |
SG11201804412SA (en) * | 2015-12-10 | 2018-06-28 | Bracco Imaging Spa | Dimeric contrast agents |
EP3223181B1 (fr) | 2016-03-24 | 2019-12-18 | Sofradim Production | Système et procédé de génération d'un modèle et de simulation d'un effet sur un site de réparation chirurgicale |
US11007283B2 (en) * | 2016-04-13 | 2021-05-18 | Bracco Imaging S.P.A. | Contrast agents |
GB201610738D0 (en) * | 2016-06-20 | 2016-08-03 | Ge Healthcare As | Chelate compounds |
JP7034160B2 (ja) | 2016-11-28 | 2022-03-11 | バイエル・ファルマ・アクティエンゲゼルシャフト | 磁気共鳴画像法に使用するための高緩和度ガドリニウムキレート化合物 |
DK3558394T3 (da) | 2016-12-21 | 2020-08-24 | Ge Healthcare As | Tetraazabicyklo-macrocykel-baseret mangan-chelatforbindelser egnede som mri-kontraststoffer |
FR3069245B1 (fr) * | 2017-07-21 | 2019-07-26 | Guerbet | Ligands macrocycliques lipophiles, leurs complexes ainsi que leurs utilisations medicales |
CN111712477B (zh) | 2017-12-20 | 2024-02-02 | 通用电气公司 | 阴离子螯合物化合物 |
WO2020030618A1 (fr) | 2018-08-06 | 2020-02-13 | Bracco Imaging Spa | Agents de contraste à base de pcta portant du gadolinium |
US11944690B2 (en) | 2018-11-23 | 2024-04-02 | Bayer Aktiengesellschaft | Formulation of contrast media and process of preparation thereof |
US11370804B2 (en) | 2019-01-17 | 2022-06-28 | Guerbet | Complex of gadolinium and a chelating ligand derived from a diastereoisomerically enriched PCTA and preparation and purification process |
FR3091873B1 (fr) | 2019-01-17 | 2020-12-25 | Guerbet Sa | Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de preparation et de purification |
US11426470B2 (en) | 2019-01-17 | 2022-08-30 | Guerbet | Complex of gadolinium and a chelating ligand derived of a diastereoisomerically enriched PCTA and synthesis method |
FR3091872B1 (fr) * | 2019-01-17 | 2020-12-25 | Guerbet Sa | Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de synthese |
EP4143153B1 (fr) | 2020-07-16 | 2023-09-20 | Guerbet | Procédé de synthèse de diesters d'acide 2-bromoglutarique |
CN111875667B (zh) * | 2020-07-16 | 2021-12-21 | 南方科技大学 | 有机金属螯合物及其制备方法与应用、探针 |
KR20230041007A (ko) | 2020-07-17 | 2023-03-23 | 게르브 | Pcta로부터 유도된 킬레이팅 리간드의 제조 방법 |
CN114105983B (zh) * | 2021-11-09 | 2023-08-11 | 国科温州研究院(温州生物材料与工程研究所) | 手性1,4,7,10-四氮杂-2,6-吡啶环蕃衍生物及其金属螯合物的制备和应用 |
WO2024049087A1 (fr) * | 2022-09-01 | 2024-03-07 | 주식회사 테라노큐어 | Nouveau composé et agent de contraste irm le comprenant |
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FR2836916B1 (fr) * | 2002-03-05 | 2004-06-11 | Guerbet Sa | Oligomeres de chelates de gadolinium, leur application comme produits de contraste en imagerie par resonance magnetique et leurs intermediaires de synthese |
WO2005001415A2 (fr) | 2003-05-23 | 2005-01-06 | Epix Pharmaceuticals, Inc. | Isomeres optiquement purs et enrichis de ligands chelateurs et agents de contraste |
FR2856689A1 (fr) | 2003-06-25 | 2004-12-31 | Guerbet Sa | Composes specifiques a forte relaxivite |
CA2783275A1 (fr) | 2003-07-24 | 2005-02-03 | Bracco Imaging S.P.A. | Compositions radiopharmaceutiques stables et methodes pour leur preparation |
US20050136003A1 (en) | 2003-10-31 | 2005-06-23 | Casebier David S. | Novel chemical agents comprising a cardiotonic moiety and an imaging moiety and methods of their use |
GB0326546D0 (en) | 2003-11-14 | 2003-12-17 | Amersham Plc | Inhibitor imaging agents |
WO2005049095A2 (fr) | 2003-11-24 | 2005-06-02 | Amersham Health As | Agent de contraste |
EP1699466A4 (fr) | 2003-12-23 | 2009-03-11 | Bracco Spa | Nouveaux composes utiles comme chelateurs de metaux |
WO2006002873A2 (fr) | 2004-07-02 | 2006-01-12 | Bracco Imaging Spa | Agents de contraste a relaxivite accrue |
FR2891830B1 (fr) * | 2005-10-07 | 2011-06-24 | Guerbet Sa | Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale |
-
2005
- 2005-10-07 FR FR0510289A patent/FR2891830B1/fr active Active
-
2006
- 2006-10-09 US US12/083,092 patent/US8114863B2/en active Active
- 2006-10-09 WO PCT/EP2006/067214 patent/WO2007042506A1/fr active Application Filing
- 2006-10-09 JP JP2008534029A patent/JP5317270B2/ja active Active
- 2006-10-09 KR KR1020087010991A patent/KR20080080495A/ko active Application Filing
- 2006-10-09 PT PT06807100T patent/PT1931673E/pt unknown
- 2006-10-09 CN CN201310087412.9A patent/CN103224495B/zh active Active
- 2006-10-09 BR BRPI0617151A patent/BRPI0617151B8/pt active IP Right Grant
- 2006-10-09 EP EP12153144.6A patent/EP2457914B1/fr active Active
- 2006-10-09 DK DK06807100.0T patent/DK1931673T3/da active
- 2006-10-09 ES ES06807100T patent/ES2390092T3/es active Active
- 2006-10-09 PL PL06807100T patent/PL1931673T3/pl unknown
- 2006-10-09 KR KR1020147009046A patent/KR101440761B1/ko active IP Right Grant
- 2006-10-09 CN CN2006800416152A patent/CN101305006B/zh active Active
- 2006-10-09 ES ES12153144.6T patent/ES2519369T3/es active Active
- 2006-10-09 EP EP06807100A patent/EP1931673B1/fr active Active
- 2006-10-09 CA CA2625207A patent/CA2625207C/fr active Active
-
2013
- 2013-05-20 JP JP2013105720A patent/JP5731572B2/ja active Active
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- 2024-02-19 FR FR24C1006C patent/FR24C1006I1/fr active Active
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Also Published As
Publication number | Publication date |
---|---|
JP2013209400A (ja) | 2013-10-10 |
KR20080080495A (ko) | 2008-09-04 |
PT1931673E (pt) | 2012-09-24 |
JP5731572B2 (ja) | 2015-06-10 |
NL301259I2 (nl) | 2024-03-25 |
EP2457914B1 (fr) | 2014-08-06 |
US8114863B2 (en) | 2012-02-14 |
EP1931673A1 (fr) | 2008-06-18 |
CN103224495A (zh) | 2013-07-31 |
EP1931673B1 (fr) | 2012-08-29 |
CN101305006A (zh) | 2008-11-12 |
US20090169479A1 (en) | 2009-07-02 |
BRPI0617151B1 (pt) | 2020-08-11 |
ES2519369T3 (es) | 2014-11-06 |
CA2625207C (fr) | 2014-05-13 |
BRPI0617151B8 (pt) | 2021-07-27 |
JP5317270B2 (ja) | 2013-10-16 |
PL1931673T3 (pl) | 2012-11-30 |
BRPI0617151A2 (pt) | 2011-07-12 |
CN101305006B (zh) | 2013-04-24 |
JP2009513574A (ja) | 2009-04-02 |
FR24C1006I1 (fr) | 2024-04-19 |
CA2625207A1 (fr) | 2007-04-19 |
WO2007042506A1 (fr) | 2007-04-19 |
KR20140060565A (ko) | 2014-05-20 |
FIC20240003I1 (fi) | 2024-02-26 |
ES2390092T3 (es) | 2012-11-06 |
KR101440761B1 (ko) | 2014-09-17 |
CN103224495B (zh) | 2015-07-15 |
EP2457914A1 (fr) | 2012-05-30 |
FR2891830A1 (fr) | 2007-04-13 |
DK1931673T3 (da) | 2012-10-08 |
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