CA2489440A1 - Anti-igf-i receptor antibody - Google Patents
Anti-igf-i receptor antibody Download PDFInfo
- Publication number
- CA2489440A1 CA2489440A1 CA002489440A CA2489440A CA2489440A1 CA 2489440 A1 CA2489440 A1 CA 2489440A1 CA 002489440 A CA002489440 A CA 002489440A CA 2489440 A CA2489440 A CA 2489440A CA 2489440 A1 CA2489440 A1 CA 2489440A1
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- CA
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- Prior art keywords
- antibody
- ser
- seq
- igf
- gly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| PCT/US2003/016211 WO2003106621A2 (en) | 2002-06-14 | 2003-06-12 | Anti-igf-i receptor antibody |
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| MX337162B (es) | 2001-01-05 | 2016-02-15 | Pfizer | Anticuerpos contra el receptor del factor de crecimiento similar a insulina. |
| US20080152649A1 (en) * | 2002-03-01 | 2008-06-26 | Xencor, Inc. | Optimized igf-1r antibodies and methods of using the same |
| US20050276812A1 (en) * | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Antibody-drug conjugates and methods |
| EP2316922B1 (en) * | 2002-05-24 | 2013-05-22 | Merck Sharp & Dohme Corp. | Neutralizing human anti-IGFR antibody |
| US7538195B2 (en) | 2002-06-14 | 2009-05-26 | Immunogen Inc. | Anti-IGF-I receptor antibody |
| US8034904B2 (en) * | 2002-06-14 | 2011-10-11 | Immunogen Inc. | Anti-IGF-I receptor antibody |
| US20060002935A1 (en) * | 2002-06-28 | 2006-01-05 | Domantis Limited | Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor |
| US7541440B2 (en) * | 2002-09-30 | 2009-06-02 | Immunomedics, Inc. | Chimeric, human and humanized anti-granulocyte antibodies and methods of use |
| US7919083B2 (en) * | 2002-11-15 | 2011-04-05 | Morehouse School Of Medicine | Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms |
| US7132111B2 (en) * | 2003-01-03 | 2006-11-07 | Epien Medical, Inc. | Odorless formulation for treating mucosal discontinuities |
| CA2524305C (en) * | 2003-05-01 | 2015-12-08 | Imclone Systems Incorporated | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
| ES2541134T3 (es) | 2003-05-12 | 2015-07-16 | Helion Biotech Aps | Anticuerpos de MASP-2 |
| AR046071A1 (es) * | 2003-07-10 | 2005-11-23 | Hoffmann La Roche | Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos |
| ES2351395T3 (es) | 2003-08-13 | 2011-02-04 | Pfizer Products Inc. | Anticuerpos humanos modificados anti-igf-1r. |
| US7326567B2 (en) | 2003-11-12 | 2008-02-05 | Schering Corporation | Plasmid system for multigene expression |
| AR046639A1 (es) * | 2003-11-21 | 2005-12-14 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti- igfr1 |
| KR20070001883A (ko) * | 2003-12-08 | 2007-01-04 | 이뮤노젠 아이엔씨 | 항-아이쥐에프-아이 수용체 항체 |
| ES2432112T3 (es) * | 2004-02-10 | 2013-11-29 | The Regents Of The University Of Colorado, A Body Corporate | Inhibición del factor B, de la vía alternativa del complemento y métodos relacionados |
| KR101245983B1 (ko) * | 2004-03-31 | 2013-06-28 | 제넨테크, 인크. | 인간화 항-ｔｇｆ-베타 항체 |
| US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| US7919094B2 (en) * | 2004-06-10 | 2011-04-05 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
| JP2008506681A (ja) * | 2004-07-16 | 2008-03-06 | ファイザー・プロダクツ・インク | 抗ｉｇｆ−１ｒ抗体を用いる非血液性の悪性腫瘍の併用療法 |
| AU2011236042B2 (en) * | 2004-07-29 | 2013-09-05 | Pierre Fabre Medicament | Novel anti-IGF-IR antibodies and uses thereof |
| FR2873699B1 (fr) * | 2004-07-29 | 2009-08-21 | Pierre Fabre Medicament Sa | Nouveaux anticorps anti igf ir rt leurs utilisations |
| EP1824987B1 (en) * | 2004-11-16 | 2013-08-21 | KaloBios Pharmaceuticals, Inc. | Immunoglobulin variable region cassette exchange |
| EP2283831A3 (en) | 2004-12-03 | 2013-10-23 | Merck Sharp & Dohme Corp. | Biomakers for pre-selection of patients for anti-IGF1R therapy |
| MY146381A (en) | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
| US7524831B2 (en) | 2005-03-02 | 2009-04-28 | Schering Corporation | Treatments for Flaviviridae virus infection |
| EP1879587A2 (en) * | 2005-04-15 | 2008-01-23 | Schering Corporation | Methods and compositions for treating or preventing cancer |
| WO2006114115A1 (de) | 2005-04-26 | 2006-11-02 | Trion Pharma Gmbh | Kombination von antikörpern mit glukokortikoiden zur behandlung von krebs |
| EP1885398B1 (en) * | 2005-05-26 | 2015-07-08 | The Regents of the University of Colorado, a body corporate | Inhibition of the alternative complement pathway for treatment of traumatic brain injury, spinal cord injury and related conditions |
| CN101287761A (zh) * | 2005-06-15 | 2008-10-15 | 先灵公司 | 抗-igf1r抗体制剂 |
| CN101500597A (zh) | 2005-06-17 | 2009-08-05 | 伊姆克罗尼系统公司 | 治疗转移性骨癌的受体拮抗剂 |
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| WO2025027472A2 (en) | 2023-07-31 | 2025-02-06 | Astrazeneca Ab | Cd123 antibody-drug conjugates and methods of using the same |
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| CA2090702A1 (en) | 1990-08-28 | 1992-03-01 | Michael C. Kiefer | Insulin-like growth factor binding protein igfbp-5 |
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