CA2459999A1 - Antagonists_and agonists of igf-1 receptor - Google Patents

Antagonists_and agonists of igf-1 receptor Download PDF

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Publication number
CA2459999A1
CA2459999A1 CA002459999A CA2459999A CA2459999A1 CA 2459999 A1 CA2459999 A1 CA 2459999A1 CA 002459999 A CA002459999 A CA 002459999A CA 2459999 A CA2459999 A CA 2459999A CA 2459999 A1 CA2459999 A1 CA 2459999A1
Authority
CA
Canada
Prior art keywords
insulin
seq
growth factor
amino acid
factor receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002459999A
Other languages
English (en)
French (fr)
Inventor
Renuka Pillutla
Olga Dedova
Arthur J. Blume
Neil I. Goldstein
Renee Brissette
Pinger Wang
Hao Liu
Ku-Chuan Hsiao
Michael Lennick
Paul Fletcher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Antyra Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2459999A1 publication Critical patent/CA2459999A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002459999A 2001-09-24 2002-09-24 Antagonists_and agonists of igf-1 receptor Abandoned CA2459999A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/962,756 2001-09-24
US09/962,756 US6875741B2 (en) 1998-09-02 2001-09-24 Insulin and IGF-1 receptor agonists and antagonists
PCT/US2002/030412 WO2003027246A2 (en) 2001-09-24 2002-09-24 Antagonists

Publications (1)

Publication Number Publication Date
CA2459999A1 true CA2459999A1 (en) 2003-04-03

Family

ID=25506313

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002459999A Abandoned CA2459999A1 (en) 2001-09-24 2002-09-24 Antagonists_and agonists of igf-1 receptor
CA002460055A Abandoned CA2460055A1 (en) 2001-09-24 2002-09-24 Insulin and igf-1 receptor agonists and antagonists

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002460055A Abandoned CA2460055A1 (en) 2001-09-24 2002-09-24 Insulin and igf-1 receptor agonists and antagonists

Country Status (6)

Country Link
US (1) US6875741B2 (enExample)
EP (2) EP1496935A4 (enExample)
JP (2) JP2005505579A (enExample)
AU (2) AU2002341834A1 (enExample)
CA (2) CA2459999A1 (enExample)
WO (2) WO2003027246A2 (enExample)

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US8574577B2 (en) * 2008-01-03 2013-11-05 The Scripps Research Institute VEGF antibodies comprising modular recognition domains
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Also Published As

Publication number Publication date
JP2005505579A (ja) 2005-02-24
JP2005517741A (ja) 2005-06-16
WO2003070747A3 (en) 2004-11-11
AU2002341834A1 (en) 2003-04-07
WO2003070747A2 (en) 2003-08-28
WO2003027246A3 (en) 2003-07-31
EP1432433A2 (en) 2004-06-30
AU2002366384A8 (en) 2003-09-09
US20030195147A1 (en) 2003-10-16
EP1496935A2 (en) 2005-01-19
WO2003027246A2 (en) 2003-04-03
AU2002366384A1 (en) 2003-09-09
CA2460055A1 (en) 2003-08-28
US6875741B2 (en) 2005-04-05
EP1432433A4 (en) 2006-08-30
EP1496935A4 (en) 2006-06-07

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Legal Events

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EEER Examination request
FZDE Discontinued