CA2446806A1 - Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26 - Google Patents
Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26 Download PDFInfo
- Publication number
- CA2446806A1 CA2446806A1 CA002446806A CA2446806A CA2446806A1 CA 2446806 A1 CA2446806 A1 CA 2446806A1 CA 002446806 A CA002446806 A CA 002446806A CA 2446806 A CA2446806 A CA 2446806A CA 2446806 A1 CA2446806 A1 CA 2446806A1
- Authority
- CA
- Canada
- Prior art keywords
- cell
- antibody
- cancer
- cells
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29053101P | 2001-05-11 | 2001-05-11 | |
| US60/290,531 | 2001-05-11 | ||
| PCT/US2002/014462 WO2002092127A1 (en) | 2001-05-11 | 2002-05-08 | Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2446806A1 true CA2446806A1 (en) | 2002-11-21 |
Family
ID=23116424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002446806A Abandoned CA2446806A1 (en) | 2001-05-11 | 2002-05-08 | Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7198788B2 (enExample) |
| EP (1) | EP1392361A4 (enExample) |
| JP (1) | JP2004533449A (enExample) |
| KR (1) | KR100863624B1 (enExample) |
| CN (2) | CN101172158A (enExample) |
| AU (1) | AU2002308637B2 (enExample) |
| CA (1) | CA2446806A1 (enExample) |
| WO (1) | WO2002092127A1 (enExample) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000018885A1 (en) * | 1998-09-29 | 2000-04-06 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
| IL152904A0 (en) * | 2002-01-24 | 2003-06-24 | Gamida Cell Ltd | Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations |
| EP1465982A4 (en) * | 2002-01-25 | 2006-06-07 | Gamida Cell Ltd | PROCESS FOR EXPANSION OF STEM AND PRESERVATIVE CELLS AND EXPANDED CELL POPULATIONS THEREWITH OBTAINED |
| EP1485464A4 (en) * | 2002-03-18 | 2006-11-29 | Gamida Cell Ltd | METHODS OF INDUCING DIFFERENTIATION IN EX VIVO EXPANDED STEM CELLS |
| CA2497628A1 (en) * | 2002-09-05 | 2004-03-18 | Medimmune, Inc. | Methods of preventing or treating cell malignancies by administering cd2 antagonists |
| US20050054097A1 (en) * | 2002-11-17 | 2005-03-10 | Tony Peled | EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures |
| CA2508348C (en) * | 2002-12-06 | 2016-07-12 | Millennium Pharmaceuticals, Inc. | Methods for the identification, assessment, and treatment of patients with proteasome inhibition therapy |
| US20040202666A1 (en) * | 2003-01-24 | 2004-10-14 | Immunomedics, Inc. | Anti-cancer anthracycline drug-antibody conjugates |
| WO2004087053A2 (en) | 2003-03-25 | 2004-10-14 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| MX369959B (es) | 2003-05-14 | 2019-11-27 | Immunogen Inc | Composicion de farmaco conjugado. |
| EP1625122A1 (en) | 2003-05-14 | 2006-02-15 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| US7579357B2 (en) | 2003-08-13 | 2009-08-25 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| WO2006030442A2 (en) * | 2004-09-16 | 2006-03-23 | Gamida-Cell Ltd. | Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells |
| EP1853322B1 (en) | 2005-02-11 | 2014-06-25 | ImmunoGen, Inc. | Process for preparing maytansinoid antibody conjugates |
| RU2486204C2 (ru) * | 2005-07-22 | 2013-06-27 | Уай'З Терапьютикс Ко., Лтд. | Антитела против сd26 и способы их применения |
| NZ564843A (en) | 2005-08-03 | 2012-05-25 | Immunogen Inc | Immunoconjugate formulations comprising an immunoconjugate and an excipient in a buffered aqueous solution |
| WO2007024536A2 (en) | 2005-08-24 | 2007-03-01 | Immunogen, Inc. | Process for preparing maytansinoid antibody conjugates |
| EP1942898B2 (en) | 2005-09-14 | 2014-05-14 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors for treating diabetes |
| CN101360723A (zh) | 2005-09-16 | 2009-02-04 | 武田药品工业株式会社 | 制备嘧啶二酮衍生物的方法 |
| US20090162405A1 (en) * | 2006-12-14 | 2009-06-25 | Yong Qian | Proteinase-engineered cancer vaccine induces immune responses to prevent cancer and to systemically kill cancer cells |
| US8846393B2 (en) | 2005-11-29 | 2014-09-30 | Gamida-Cell Ltd. | Methods of improving stem cell homing and engraftment |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| KR101334934B1 (ko) * | 2006-12-27 | 2013-11-29 | 삼성디스플레이 주식회사 | 유기발광표시장치의 에이징 방법 |
| JP4865868B2 (ja) | 2007-03-14 | 2012-02-01 | 国立大学法人 東京大学 | 悪性中皮種の治療方法 |
| KR200450480Y1 (ko) * | 2008-09-22 | 2010-10-07 | 대우조선해양 주식회사 | 앵글 취부장치 |
| WO2010099918A1 (en) * | 2009-03-06 | 2010-09-10 | Klaus Tschira Stiftung Ggmbh | Pharmaceutical composition and method for identifying a cancerous and/or an inflammatory disease in a patient |
| SG176068A1 (en) | 2009-06-03 | 2011-12-29 | Immunogen Inc | Conjugation methods |
| US8321012B2 (en) * | 2009-12-22 | 2012-11-27 | The Invention Science Fund I, Llc | Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject |
| AU2011223883B2 (en) * | 2010-03-01 | 2015-10-08 | Cavion, Inc. | Cancer diagnosis and imaging |
| EP2554552B1 (en) * | 2010-03-26 | 2015-05-13 | The University of Tokushima | Novel anti-cd98 antibody and use thereof |
| CN103717262B (zh) | 2011-03-29 | 2017-09-15 | 伊缪诺金公司 | 通过一步法制备类美登素抗体缀合物 |
| CN104254778A (zh) * | 2012-02-10 | 2014-12-31 | 西雅图遗传学公司 | Cd30+癌症的检测和治疗 |
| AU2013219945B2 (en) | 2012-02-13 | 2017-12-07 | Gamida-Cell Ltd. | Culturing of mesenchymal stem cells |
| US9567569B2 (en) | 2012-07-23 | 2017-02-14 | Gamida Cell Ltd. | Methods of culturing and expanding mesenchymal stem cells |
| US9175266B2 (en) | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
| MX359599B (es) | 2012-10-04 | 2018-09-12 | Immunogen Inc | Uso de una membrana de pvdf para purificar conjugados de agentes de unión celular y agentes citotóxicos. |
| EP2767549A1 (en) * | 2013-02-19 | 2014-08-20 | Adienne S.A. | Anti-CD26 antibodies and uses thereof |
| US11242399B2 (en) | 2013-02-19 | 2022-02-08 | Adienne S.A. | Anti-CD26 antibodies |
| CN105407723A (zh) | 2013-03-15 | 2016-03-16 | G1治疗公司 | 高效的抗赘生剂和抗增生剂 |
| WO2014144847A2 (en) | 2013-03-15 | 2014-09-18 | G1 Therapeutics, Inc. | Hspc-sparing treatments for rb-positive abnormal cellular proliferation |
| JP2015030666A (ja) | 2013-07-31 | 2015-02-16 | 学校法人順天堂 | 抗ヒトcd26モノクローナル抗体又はその抗原結合性断片 |
| CN103709251B (zh) * | 2013-12-19 | 2016-04-13 | 江苏众红生物工程创药研究院有限公司 | 全人源抗cd26抗体及其应用 |
| CN103694352B (zh) * | 2013-12-19 | 2015-12-09 | 江苏众红生物工程创药研究院有限公司 | 一种抗 cd26 抗体及其制备方法 |
| TWI677505B (zh) * | 2014-08-18 | 2019-11-21 | 瑞士商艾迪安納股份有限公司 | 抗cd26抗體及其用途 |
| WO2016040858A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
| WO2016040848A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors |
| KR20230144660A (ko) | 2014-12-04 | 2023-10-16 | 셀진 코포레이션 | 생체분자 컨쥬게이트 |
| EP3242686B1 (en) * | 2015-01-09 | 2020-07-08 | Medimmune, LLC | Assay to detect human dpp-4 |
| RU2020142534A (ru) * | 2015-09-11 | 2021-02-01 | И' с АК Ко., Лтд. | Композиция для лечения рака, объединяющая анти-cd26 антитело и другое противораковое средство |
| PT3380525T (pt) | 2015-11-25 | 2024-02-05 | Immunogen Inc | Formulações farmacêuticas e métodos que as utilizam |
| US11963980B2 (en) * | 2016-04-25 | 2024-04-23 | Musc Foundation For Research Development | Activated CD26-high immune cells and CD26-negative immune cells and uses thereof |
| MA51309A (fr) * | 2017-12-22 | 2021-03-31 | Adienne S A | Procédé cellulaire quantitatif pour déterminer l'activité biologique d'un ligand anti-cd26 |
| CN109709337B (zh) * | 2018-12-28 | 2021-09-14 | 江苏众红生物工程创药研究院有限公司 | 人cd26的免疫组化检测试剂盒及其临床应用 |
| CN109535255B (zh) * | 2018-12-28 | 2020-10-27 | 江苏众红生物工程创药研究院有限公司 | 一种抗人cd26抗体及其在检测试剂盒中的应用 |
| EP3972606A4 (en) * | 2019-05-20 | 2022-09-21 | Mayo Foundation for Medical Education and Research | TREATMENT OF CHRONIC LIVER DISEASE |
| CA3155930A1 (en) * | 2019-09-27 | 2021-04-01 | Starkage Therapeutics | Senescent cell-associated antigen-binding domains, antibodies and chimeric antigen receptors comprising the same, and uses thereof |
| US11723926B2 (en) | 2019-09-27 | 2023-08-15 | Starkage Therapeutics | Senescent cell-associated antigen-binding domains, antibodies and chimeric antigen receptors comprising the same, and uses thereof |
| US10988479B1 (en) | 2020-06-15 | 2021-04-27 | G1 Therapeutics, Inc. | Morphic forms of trilaciclib and methods of manufacture thereof |
| WO2022220232A1 (ja) * | 2021-04-12 | 2022-10-20 | 国立大学法人 東京大学 | すい臓がん検出用蛍光プローブ |
| MX2023012633A (es) | 2021-05-13 | 2023-11-09 | Adienne S A | Metodos de tratamiento de la enfermedad de injerto contra hospedero. |
| KR20240007230A (ko) | 2021-05-13 | 2024-01-16 | 아디에네 에스.에이. | 피부근염을 치료하는 방법 |
| CN116023491A (zh) * | 2021-10-25 | 2023-04-28 | 江苏众红生物工程创药研究院有限公司 | 抗cd26抗体及其应用 |
| CN116549629A (zh) * | 2022-01-30 | 2023-08-08 | 江苏众红生物工程创药研究院有限公司 | Cd45作为生物标志物在筛查cd26抗体或其衍生物治疗肿瘤有效性和精准性中的应用 |
| CN114878820A (zh) * | 2022-05-30 | 2022-08-09 | 湛江中心人民医院 | 肺腺癌病理诊断标志物及其应用 |
| WO2025027529A1 (en) | 2023-07-31 | 2025-02-06 | Advesya | Anti-il-1rap antibody drug conjugates and methods of use thereof |
| CN117568477B (zh) * | 2023-10-17 | 2024-11-19 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | Dpp4作为nk/t细胞淋巴瘤肿瘤标志物的应用 |
| TW202530255A (zh) | 2023-12-15 | 2025-08-01 | 法商亞維西亞有限公司 | 抗il-1rap結合結構域及其抗體-藥物偶聯物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5120642A (en) * | 1989-11-28 | 1992-06-09 | Coulter Corporation | Monoclonal antibody which distinguishes helper inducer and suppressor inducer cd4+ lymphocytes |
| US5863904A (en) * | 1995-09-26 | 1999-01-26 | The University Of Michigan | Methods for treating cancers and restenosis with P21 |
| US6951924B2 (en) * | 1997-03-14 | 2005-10-04 | Human Genome Sciences, Inc. | Antibodies against secreted protein HTEBYII |
| US6573096B1 (en) * | 2000-04-01 | 2003-06-03 | The Research Foundation At State University Of New York | Compositions and methods for inhibition of cancer invasion and angiogenesis |
| WO2002004610A2 (en) * | 2000-07-10 | 2002-01-17 | Bayer Aktiengesellschaft | Regulation of human dipeptidyl-peptidase iv-like enzyme |
| NZ525443A (en) * | 2000-10-12 | 2006-04-28 | Ferring Bv | Dipeptidyl peptidase IV related genes |
-
2002
- 2002-05-08 CA CA002446806A patent/CA2446806A1/en not_active Abandoned
- 2002-05-08 AU AU2002308637A patent/AU2002308637B2/en not_active Ceased
- 2002-05-08 WO PCT/US2002/014462 patent/WO2002092127A1/en not_active Ceased
- 2002-05-08 CN CNA2007101410677A patent/CN101172158A/zh active Pending
- 2002-05-08 KR KR1020037014644A patent/KR100863624B1/ko not_active Expired - Fee Related
- 2002-05-08 EP EP02769684A patent/EP1392361A4/en not_active Withdrawn
- 2002-05-08 JP JP2002589043A patent/JP2004533449A/ja active Pending
- 2002-05-08 CN CNB028117077A patent/CN100341572C/zh not_active Expired - Fee Related
- 2002-05-10 US US10/143,553 patent/US7198788B2/en not_active Expired - Lifetime
-
2007
- 2007-02-16 US US11/676,164 patent/US7658923B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002308637B2 (en) | 2007-05-17 |
| CN1671415A (zh) | 2005-09-21 |
| EP1392361A1 (en) | 2004-03-03 |
| CN100341572C (zh) | 2007-10-10 |
| EP1392361A4 (en) | 2009-08-05 |
| WO2002092127A1 (en) | 2002-11-21 |
| US7658923B2 (en) | 2010-02-09 |
| US7198788B2 (en) | 2007-04-03 |
| JP2004533449A (ja) | 2004-11-04 |
| CN101172158A (zh) | 2008-05-07 |
| US20030031665A1 (en) | 2003-02-13 |
| US20070207143A1 (en) | 2007-09-06 |
| KR100863624B1 (ko) | 2008-10-15 |
| KR20040029984A (ko) | 2004-04-08 |
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