CA2413186A1 - Molecules de matrice extracellulaire et d'adhesion cellulaire - Google Patents

Molecules de matrice extracellulaire et d'adhesion cellulaire Download PDF

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Publication number
CA2413186A1
CA2413186A1 CA002413186A CA2413186A CA2413186A1 CA 2413186 A1 CA2413186 A1 CA 2413186A1 CA 002413186 A CA002413186 A CA 002413186A CA 2413186 A CA2413186 A CA 2413186A CA 2413186 A1 CA2413186 A1 CA 2413186A1
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Canada
Prior art keywords
polynucleotide
seq
polypeptide
amino acid
sequence
Prior art date
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Abandoned
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CA002413186A
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English (en)
Inventor
Y. Tom Tang
Henry Yue
Yalda Azimzai
Ann He
Sajeev Batra
Terence P. Lo
Danniel B. Nguyen
John D. Burrill
Gregory A. Marcus
Kurt A. Zingler
Ameena R. Gandhi
Preeti G. Lal
Liam Kearney
Neil Burford
Monique G. Yao
Narinder K. Chawla
Vicki S. Elliott
Chandra S. Arvizu
Farrah Anis Khan
Mariah R. Baughn
April J. A. Hafalia
Jennifer L. Policky
Janice K. Au-Young
Yan Lu
Mark L. Borowsky
Dyung Aina M. Lu
Jayalaxmi Ramkumar
Junming Yang
Rajagopal Gururajan
Bridget A. Warren
Kimberly J. Gietzen
Yuming Xu
Deborah A. Kallick
Ernestine A. Lee
Kavitha Thangavelu
Angelo M. Delegeane
Sally Lee
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Incyte Corp
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Individual
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Publication of CA2413186A1 publication Critical patent/CA2413186A1/fr
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Abstract

La présente invention concerne des molécules humaines de matrice extracellulaire et d'adhésion cellulaire ou "ECMCAD" (ExtraCellular Matrix and Cell ADhesion) ainsi que des polynucléotides qui identifient et codent les ECMCAD. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne enfin des procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles associés à l'expression aberrante des ECMCAD.
CA002413186A 2000-06-30 2001-06-29 Molecules de matrice extracellulaire et d'adhesion cellulaire Abandoned CA2413186A1 (fr)

Applications Claiming Priority (15)

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US21545400P 2000-06-30 2000-06-30
US60/215,454 2000-06-30
US21946200P 2000-07-18 2000-07-18
US60/219,462 2000-07-18
US24011100P 2000-10-12 2000-10-12
US24010600P 2000-10-12 2000-10-12
US60/240,106 2000-10-12
US60/240,111 2000-10-12
US24402100P 2000-10-27 2000-10-27
US60/244,021 2000-10-27
US24888700P 2000-11-14 2000-11-14
US60/248,887 2000-11-14
US24957000P 2000-11-16 2000-11-16
US60/249,570 2000-11-16
PCT/US2001/021067 WO2002002634A2 (fr) 2000-06-30 2001-06-29 Molécules de matrice extracellulaire et d'adhésion cellulaire

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JP (1) JP2004528003A (fr)
AU (1) AU2001273151A1 (fr)
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AU2001273151A1 (en) 2002-01-14
EP1383892A2 (fr) 2004-01-28
JP2004528003A (ja) 2004-09-16
WO2002002634A2 (fr) 2002-01-10

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