WO2002002634A3 - Molécules de matrice extracellulaire et d'adhésion cellulaire - Google Patents

Molécules de matrice extracellulaire et d'adhésion cellulaire Download PDF

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Publication number
WO2002002634A3
WO2002002634A3 PCT/US2001/021067 US0121067W WO0202634A3 WO 2002002634 A3 WO2002002634 A3 WO 2002002634A3 US 0121067 W US0121067 W US 0121067W WO 0202634 A3 WO0202634 A3 WO 0202634A3
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WIPO (PCT)
Prior art keywords
extracellular matrix
cell adhesion
human extracellular
ecmcad
adhesion polypeptides
Prior art date
Application number
PCT/US2001/021067
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English (en)
Other versions
WO2002002634A2 (fr
Inventor
Y Tom Tang
Henry Yue
Yalda Azimzai
Ann He
Sajeev Batra
Terence P Lo
Danniel B Nguyen
John D Burrill
Gregory A Marcus
Kurt A Zingler
Original Assignee
Incyte Genomics Inc
Y Tom Tang
Henry Yue
Yalda Azimzai
Ann He
Sajeev Batra
Terence P Lo
Danniel B Nguyen
John D Burrill
Gregory A Marcus
Kurt A Zingler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Incyte Genomics Inc, Y Tom Tang, Henry Yue, Yalda Azimzai, Ann He, Sajeev Batra, Terence P Lo, Danniel B Nguyen, John D Burrill, Gregory A Marcus, Kurt A Zingler filed Critical Incyte Genomics Inc
Priority to AU2001273151A priority Critical patent/AU2001273151A1/en
Priority to EP01952392A priority patent/EP1383892A2/fr
Priority to CA002413186A priority patent/CA2413186A1/fr
Priority to US10/312,352 priority patent/US20040053824A1/en
Priority to JP2002507885A priority patent/JP2004528003A/ja
Publication of WO2002002634A2 publication Critical patent/WO2002002634A2/fr
Publication of WO2002002634A3 publication Critical patent/WO2002002634A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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Abstract

La présente invention concerne des molécules humaines de matrice extracellulaire et d'adhésion cellulaire ou 'ECMCAD' (ExtraCellular Matrix and Cell ADhesion) ainsi que des polynucléotides qui identifient et codent les ECMCAD. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne enfin des procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles associés à l'expression aberrante des ECMCAD.
PCT/US2001/021067 2000-06-30 2001-06-29 Molécules de matrice extracellulaire et d'adhésion cellulaire WO2002002634A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2001273151A AU2001273151A1 (en) 2000-06-30 2001-06-29 Human extracellular matrix and cell adhesion polypeptides
EP01952392A EP1383892A2 (fr) 2000-06-30 2001-06-29 Proteines de matricielles extracellulaires et d'adhesions cellulaires humaines
CA002413186A CA2413186A1 (fr) 2000-06-30 2001-06-29 Molecules de matrice extracellulaire et d'adhesion cellulaire
US10/312,352 US20040053824A1 (en) 2001-06-29 2001-06-29 Extracellular matrix and cell adhesion molecules
JP2002507885A JP2004528003A (ja) 2000-06-30 2001-06-29 細胞外マトリクスおよび細胞接着分子

Applications Claiming Priority (14)

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US21545400P 2000-06-30 2000-06-30
US60/215,454 2000-06-30
US21946200P 2000-07-18 2000-07-18
US60/219,462 2000-07-18
US24010600P 2000-10-12 2000-10-12
US24011100P 2000-10-12 2000-10-12
US60/240,111 2000-10-12
US60/240,106 2000-10-12
US24402100P 2000-10-27 2000-10-27
US60/244,021 2000-10-27
US24888700P 2000-11-14 2000-11-14
US60/248,887 2000-11-14
US24957000P 2000-11-16 2000-11-16
US60/249,570 2000-11-16

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CA2413186A1 (fr) 2002-01-10

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