WO2004009797A3 - Molecules de modification et d'entretien de proteines - Google Patents

Molecules de modification et d'entretien de proteines Download PDF

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Publication number
WO2004009797A3
WO2004009797A3 PCT/US2003/023249 US0323249W WO2004009797A3 WO 2004009797 A3 WO2004009797 A3 WO 2004009797A3 US 0323249 W US0323249 W US 0323249W WO 2004009797 A3 WO2004009797 A3 WO 2004009797A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein modification
pmmm
maintenance molecules
molecules
maintenance
Prior art date
Application number
PCT/US2003/023249
Other languages
English (en)
Other versions
WO2004009797A2 (fr
Inventor
Vicki S Elliott
Anita Swarnakar
Jennifer A Griffin
Ernestine A Lee
William W Sprague
April J A Hafalia
Soo Yeun Lee
Amy E Kable
Craig H Ison
Original Assignee
Incyte Corp
Vicki S Elliott
Anita Swarnakar
Jennifer A Griffin
Ernestine A Lee
William W Sprague
April J A Hafalia
Soo Yeun Lee
Amy E Kable
Craig H Ison
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp, Vicki S Elliott, Anita Swarnakar, Jennifer A Griffin, Ernestine A Lee, William W Sprague, April J A Hafalia, Soo Yeun Lee, Amy E Kable, Craig H Ison filed Critical Incyte Corp
Priority to AU2003268023A priority Critical patent/AU2003268023A1/en
Publication of WO2004009797A2 publication Critical patent/WO2004009797A2/fr
Publication of WO2004009797A3 publication Critical patent/WO2004009797A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Dans divers modes de réalisation, l'invention concerne des molécules de modification et d'entretien de protéines (PMMM) humaines ainsi que des polynucléotides identifiant ces PMMM et codant pour celles-ci. Dans certains modes de réalisation, l'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Dans d'autres modes de réalisation, elle concerne des méthodes de diagnostic, de traitement ou de prévention de troubles associés à l'expression aberrante des PMMM.
PCT/US2003/023249 2002-07-23 2003-07-23 Molecules de modification et d'entretien de proteines WO2004009797A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003268023A AU2003268023A1 (en) 2002-07-23 2003-07-23 Protein modification and maintenance molecules

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US39814302P 2002-07-23 2002-07-23
US60/398,143 2002-07-23
US40245802P 2002-08-09 2002-08-09
US60/402,458 2002-08-09
US40328902P 2002-08-12 2002-08-12
US60/403,289 2002-08-12
US40647202P 2002-08-27 2002-08-27
US60/406,472 2002-08-27
US40935402P 2002-09-06 2002-09-06
US60/409,354 2002-09-06

Publications (2)

Publication Number Publication Date
WO2004009797A2 WO2004009797A2 (fr) 2004-01-29
WO2004009797A3 true WO2004009797A3 (fr) 2004-12-02

Family

ID=30773751

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/023249 WO2004009797A2 (fr) 2002-07-23 2003-07-23 Molecules de modification et d'entretien de proteines

Country Status (2)

Country Link
AU (1) AU2003268023A1 (fr)
WO (1) WO2004009797A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1851543A2 (fr) 2005-02-24 2007-11-07 Compugen Ltd. Nouveaux marqueurs diagnostiques, en particulier pour l'imagerie in vivo, et dosage et procédés d'utilisation associés
US7943328B1 (en) 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
JP2010507387A (ja) 2006-10-25 2010-03-11 クアーク・ファーマスーティカルス、インコーポレイテッド 新規のｓｉＲＮＡおよびその使用方法
EP2231168A4 (fr) 2007-10-03 2012-01-04 Quark Pharmaceuticals Inc Nouvelles structures d'arnsi
PE20140608A1 (es) 2010-09-22 2014-06-12 Alios Biopharma Inc Analogos de nucleotidos sustituidos
EP2794630A4 (fr) 2011-12-22 2015-04-01 Alios Biopharma Inc Analogues de nucléotide phosphorothioate substitués
WO2013142157A1 (fr) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Combinaisons pharmaceutiques comprenant un analogue thionucléotidique

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998011236A1 (fr) * 1996-09-11 1998-03-19 Smithkline Beecham Plc Protease aspartique
WO1998022597A2 (fr) * 1996-11-20 1998-05-28 Oklahoma Medical Research Foundation Clonage et caracterisation de napsine, une protease aspartique
WO2000004137A1 (fr) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Proteases aspartiques humaines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998011236A1 (fr) * 1996-09-11 1998-03-19 Smithkline Beecham Plc Protease aspartique
WO1998022597A2 (fr) * 1996-11-20 1998-05-28 Oklahoma Medical Research Foundation Clonage et caracterisation de napsine, une protease aspartique
WO2000004137A1 (fr) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Proteases aspartiques humaines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TATNELL P.J. ET AL: "Napsins: new human aspartic proteinases - Distinction between two closely related genes", FEBS LETTERS, vol. 441, 1998, pages 43 - 48, XP004258868 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Also Published As

Publication number Publication date
WO2004009797A2 (fr) 2004-01-29
AU2003268023A1 (en) 2004-02-09
AU2003268023A8 (en) 2004-02-09

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