CA2391205A1 - Benzoic acid substituted benzopyrans for the treatment of atherosclerosis - Google Patents

Benzoic acid substituted benzopyrans for the treatment of atherosclerosis Download PDF

Info

Publication number
CA2391205A1
CA2391205A1 CA002391205A CA2391205A CA2391205A1 CA 2391205 A1 CA2391205 A1 CA 2391205A1 CA 002391205 A CA002391205 A CA 002391205A CA 2391205 A CA2391205 A CA 2391205A CA 2391205 A1 CA2391205 A1 CA 2391205A1
Authority
CA
Canada
Prior art keywords
alkyl
atherosclerosis
mammal
carboxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002391205A
Other languages
English (en)
French (fr)
Inventor
Saralyn Lindsey
Patricia-Ann Bourassa
Robert Joseph Aiello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of CA2391205A1 publication Critical patent/CA2391205A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002391205A 2001-06-28 2002-06-25 Benzoic acid substituted benzopyrans for the treatment of atherosclerosis Abandoned CA2391205A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30171201P 2001-06-28 2001-06-28
US60/301,712 2001-06-28
US32825401P 2001-10-10 2001-10-10
US60/328,254 2001-10-10

Publications (1)

Publication Number Publication Date
CA2391205A1 true CA2391205A1 (en) 2002-12-28

Family

ID=26972559

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002391205A Abandoned CA2391205A1 (en) 2001-06-28 2002-06-25 Benzoic acid substituted benzopyrans for the treatment of atherosclerosis

Country Status (12)

Country Link
EP (1) EP1270000A3 (cg-RX-API-DMAC7.html)
JP (1) JP2003034638A (cg-RX-API-DMAC7.html)
KR (1) KR20030015828A (cg-RX-API-DMAC7.html)
CN (1) CN1394602A (cg-RX-API-DMAC7.html)
AU (1) AU4239302A (cg-RX-API-DMAC7.html)
CA (1) CA2391205A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20022076A3 (cg-RX-API-DMAC7.html)
HK (1) HK1049795A1 (cg-RX-API-DMAC7.html)
HU (1) HUP0202114A3 (cg-RX-API-DMAC7.html)
IL (1) IL150340A0 (cg-RX-API-DMAC7.html)
PL (1) PL354770A1 (cg-RX-API-DMAC7.html)
SK (1) SK8682002A3 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4476934B2 (ja) * 2003-04-14 2010-06-09 明治乳業株式会社 新規ペプチドおよび免疫賦活剤、機能性食品ならびに機能性食品の製造方法
JP2008506768A (ja) * 2004-07-22 2008-03-06 ファルマシア コーポレーション Ｃｏｘ−２選択的阻害剤とｌｔｂ４受容体アンタゴニストを組み合わせて用いる炎症および疼痛を治療するための組成物
PT1888033E (pt) * 2005-06-09 2014-05-15 Meda Ab Método e composição para tratamento de distúrbios inflamatórios
EP3383389B1 (en) * 2015-11-30 2021-04-28 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as blt1 antagonists
WO2017095722A1 (en) 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as blt1 antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3720493A1 (de) * 1987-06-20 1989-01-26 Nattermann A & Cie Arzneizubereitungen mit mikronisierten ebselen-kristallen
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
DE4228200A1 (de) * 1992-08-25 1994-03-03 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
NZ285156A (en) * 1994-10-13 1999-01-28 Pfizer Benzopyran and benzo-fused compounds, preparation and use as leukotriene b4 antagonists (ltb4)
US5939452A (en) * 1994-10-13 1999-08-17 Pfizer Inc Benzopyran and benzo-fused compounds, their preparation and their use as leukotriene B4' (LTB4) antagonists
US6342510B1 (en) * 1995-06-12 2002-01-29 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitors and a leukotriene B4 receptor antagonist
DE19636689A1 (de) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg Neue Benzamidinderivate
YU13299A (sh) * 1996-09-16 2001-03-07 Pfizer Inc. Postupak i intermedijari za dobijanje hromanolnih derivata
EP0963755A3 (en) * 1998-04-16 2001-03-14 Pfizer Products Inc. Use of benzopyranes for preventing allograft rejection
AU5687199A (en) * 1998-08-24 2000-03-14 Global Vascular Concepts, Inc. Use of anti-angiogenic agents for inhibiting vessel wall injury
JP2003225088A (ja) * 1999-09-10 2003-08-12 Meiji Seika Kaisha Ltd ヒト・ロイコトリエンｂ４第二受容体及びそれをコードするｄｎａ
AU3930201A (en) * 2000-03-17 2001-09-24 Bayer Aktiengesellschaft Regulation of human leukotriene B4-like G protein-coupled receptor

Also Published As

Publication number Publication date
HUP0202114A3 (en) 2004-07-28
KR20030015828A (ko) 2003-02-25
HUP0202114A2 (hu) 2003-01-28
CN1394602A (zh) 2003-02-05
HK1049795A1 (zh) 2003-05-30
SK8682002A3 (en) 2004-08-03
EP1270000A3 (en) 2003-02-12
JP2003034638A (ja) 2003-02-07
IL150340A0 (en) 2002-12-01
HU0202114D0 (cg-RX-API-DMAC7.html) 2002-09-28
AU4239302A (en) 2003-01-02
EP1270000A2 (en) 2003-01-02
PL354770A1 (en) 2002-12-30
CZ20022076A3 (cs) 2004-05-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued