CA2377528C - Method and apparatus for presenting thrombosis and hemostasis assay data - Google Patents

Method and apparatus for presenting thrombosis and hemostasis assay data Download PDF

Info

Publication number
CA2377528C
CA2377528C CA002377528A CA2377528A CA2377528C CA 2377528 C CA2377528 C CA 2377528C CA 002377528 A CA002377528 A CA 002377528A CA 2377528 A CA2377528 A CA 2377528A CA 2377528 C CA2377528 C CA 2377528C
Authority
CA
Canada
Prior art keywords
time
data
sample
profile
dependent measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002377528A
Other languages
English (en)
French (fr)
Other versions
CA2377528A1 (en
Inventor
Thomas B. Givens
Paul Braun
Lisa Beck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux Inc
Original Assignee
Biomerieux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Inc filed Critical Biomerieux Inc
Publication of CA2377528A1 publication Critical patent/CA2377528A1/en
Application granted granted Critical
Publication of CA2377528C publication Critical patent/CA2377528C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4905Determining clotting time of blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/22Haematology
    • G01N2800/224Haemostasis or coagulation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/22Haematology
    • G01N2800/226Thrombotic disorders, i.e. thrombo-embolism irrespective of location/organ involved, e.g. renal vein thrombosis, venous thrombosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/38Pediatrics
    • G01N2800/385Congenital anomalies
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00ICT specially adapted for the handling or processing of medical references
    • G16H70/60ICT specially adapted for the handling or processing of medical references relating to pathologies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
CA002377528A 1999-06-30 2000-06-30 Method and apparatus for presenting thrombosis and hemostasis assay data Expired - Lifetime CA2377528C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/345,080 1999-06-30
US09/345,080 US6502040B2 (en) 1997-12-31 1999-06-30 Method for presenting thrombosis and hemostasis assay data
PCT/US2000/018310 WO2001001152A1 (en) 1999-06-30 2000-06-30 Method and apparatus for presenting thrombosis and hemostasis assay data

Publications (2)

Publication Number Publication Date
CA2377528A1 CA2377528A1 (en) 2001-01-04
CA2377528C true CA2377528C (en) 2008-02-05

Family

ID=23353417

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002377528A Expired - Lifetime CA2377528C (en) 1999-06-30 2000-06-30 Method and apparatus for presenting thrombosis and hemostasis assay data

Country Status (10)

Country Link
US (1) US6502040B2 (enExample)
EP (1) EP1188060B1 (enExample)
JP (1) JP2003529046A (enExample)
KR (1) KR20020042539A (enExample)
AT (1) ATE328327T1 (enExample)
AU (1) AU768436B2 (enExample)
CA (1) CA2377528C (enExample)
DE (1) DE60028374T2 (enExample)
ES (1) ES2270850T3 (enExample)
WO (1) WO2001001152A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436628A2 (en) * 2001-06-29 2004-07-14 BioMerieux, Inc. A method for predicting an increased likelihood of antiphospholipid syndrome in a patient
US9125989B2 (en) 2003-01-23 2015-09-08 Debiotech S.A. Device for determining the characteristics of peritoneal membrane
ATE479456T1 (de) * 2002-01-28 2010-09-15 Debiotech Sa Peritonealdialysesystem
ES1063877Y (es) 2006-10-02 2007-03-16 Lafuente Flo Rosa Funda perfeccionada para cascos de motocicleta
WO2009101242A1 (en) * 2008-02-14 2009-08-20 Orion Diagnostica Oy Method for predicting a future property
WO2009135205A2 (en) * 2008-05-02 2009-11-05 Advanced Liquid Logic, Inc. Droplet actuator techniques using coagulatable samples
WO2009142744A2 (en) * 2008-05-20 2009-11-26 The University Of Vermont And State Agriculture College Predicting hemostatic risk; dependence on plasma composition
JP5982976B2 (ja) * 2012-04-13 2016-08-31 ソニー株式会社 血液凝固系解析装置、血液凝固系解析方法及びそのプログラム

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3307392A (en) 1964-05-04 1967-03-07 Research Corp Automatic prothrombin timer apparatus and method
US3458287A (en) 1965-04-29 1969-07-29 Medical Laboratory Automation Method and means of determining endpoint times in blood clotting tests
US3658480A (en) 1970-04-13 1972-04-25 Bio Data Corp Coagulation timing apparatus, and method
US4047890A (en) 1973-11-01 1977-09-13 Bio/Data Corporation Method and apparatus for determining deficiencies in enzymatic reactors particularly clotting factor levels in blood plasmas
SU590665A1 (ru) 1976-02-11 1978-01-30 Новосибирский государственный медицинский институт Способ исследовани процесса свертывани крови
US4040788A (en) 1976-04-05 1977-08-09 Sanford L. Simons Apparatus, instrumentation, and method for comparing samples
DE2635081C3 (de) 1976-08-04 1980-08-07 Bio/Data Corp., Willow Grove, Pa. (V.St.A.) Verfahren und Vorrichtung zur Bestimmung von Blutplasma-Gerinnungsfaktorpegeln
FR2364453A1 (fr) 1976-09-08 1978-04-07 Lacombe Pierre Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate
US4199748A (en) 1976-11-01 1980-04-22 Rush-Presbyterian-St. Luke's Medical Center Automated method and apparatus for classification of cells with application to the diagnosis of anemia
JPS5451893A (en) 1977-09-30 1979-04-24 Sankyo Co Measuring of blood coagulating time
JPS5822703B2 (ja) 1978-08-30 1983-05-10 三共株式会社 血液凝固測定方法
US4289498A (en) 1979-01-08 1981-09-15 Ortho Diagnostics, Inc. One-stage prothrombin assay and compositions useful therein
US4766083A (en) 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
SU1076086A1 (ru) 1982-12-28 1984-02-29 Всесоюзный Научно-Исследовательский И Конструкторский Институт Медицинской Лабораторной Техники Гемокоагулограф
US4705756A (en) 1983-01-26 1987-11-10 University Of Medicine And Dentistry Of New Jersey Method of determining the existence and/or the monitoring of a pathological condition in a mammal
EP0115459A3 (en) 1983-01-26 1986-11-20 University Of Medicine And Dentistry Of New Jersey Hematological prediction of sepsis and other disease states
JPS59203959A (ja) 1983-05-04 1984-11-19 Toa Medical Electronics Co Ltd 血液凝固時間測定装置
JPH0695095B2 (ja) 1983-11-25 1994-11-24 株式会社島津製作所 全自動血液分析装置
DE3502878A1 (de) 1985-01-29 1986-07-31 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung des fibrinolytischen zustands von plasma
JPS61272655A (ja) 1985-05-28 1986-12-02 Iryo Kogaku Kenkyusho:Kk 血小板凝集能の定量的判定方法
GB8516081D0 (en) 1985-06-25 1985-07-31 Ciba Geigy Ag Assay & purification of amyloid components
US4902630A (en) 1985-07-22 1990-02-20 Abbott Laboratories Fluorescence polarization immunoassy and reagents for measurement of c-reactive protein
US5593897A (en) 1988-04-04 1997-01-14 Northwestern University Binding of immune complexes by modified forms of C-reactive protein
AU633488B2 (en) 1988-04-04 1993-02-04 Northwestern University Binding of immune complexes by modified forms of c-reactive protein
US4965725B1 (en) 1988-04-08 1996-05-07 Neuromedical Systems Inc Neural network based automated cytological specimen classification system and method
US5156974A (en) 1988-05-27 1992-10-20 Biodata Corporation Method for determining the fibrinogen level of a blood sample
US5003065A (en) 1988-06-14 1991-03-26 Carey Merritt Compounds and process for measuring c-reactive protein
US5697369A (en) * 1988-12-22 1997-12-16 Biofield Corp. Method and apparatus for disease, injury and bodily condition screening or sensing
US5055412A (en) 1989-03-21 1991-10-08 Proksch Gary J Factor sensitive reagent for testing of blood coagulation containing ellagic acid and divalent metal ions and method of making the same
US5500345A (en) 1989-04-25 1996-03-19 Iatron Laboratories, Inc. Hybridomas producing monoclonal antibodies specific for C-reactive protein and methods for detection of C-reactive protein
JPH04505857A (ja) 1989-06-27 1992-10-15 ラッシュ―プレズビティリアン―セント ルークス メディカル センター C反応性蛋白質に対するモノクローナル抗体
WO1991001383A1 (en) 1989-07-14 1991-02-07 Michigan State University Method for diagnosing blood clotting disorders
US5051357A (en) 1989-07-14 1991-09-24 Board Of Trustees Operating Michigan State University Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor
JP3055933B2 (ja) 1989-07-20 2000-06-26 アナリティカル・コントロール・システムズ・インコーポレーテッド 改良された安定な凝固対照
SU1691741A1 (ru) 1989-08-25 1991-11-15 Донецкий государственный медицинский институт Способ прогнозировани геморрагических осложнений при травматической болезни
US4998535A (en) 1989-09-05 1991-03-12 Univ. of Washington New England Medical Center Hospitals, Inc. Thrombolysis predictive instrument
US5262303A (en) 1989-10-13 1993-11-16 Trustees Of Boston University Ligand/anti-ligand assays for adherent proteins
IE904244A1 (en) 1989-12-01 1991-06-05 Akzo Nv Direct fibrinogen assay
US5646046A (en) 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
US5169786A (en) 1989-12-19 1992-12-08 Ortho Diagnostic Systems, Inc. Method of determining levels of extrinsic and intrinsic clotting factors and protein c
ATE140034T1 (de) 1990-04-17 1996-07-15 Analytical Control Syst Inc Koagulationsassays und reagenzien
US5862304A (en) 1990-05-21 1999-01-19 Board Of Regents, The University Of Texas System Method for predicting the future occurrence of clinically occult or non-existent medical conditions
US5218529A (en) 1990-07-30 1993-06-08 University Of Georgia Research Foundation, Inc. Neural network system and methods for analysis of organic materials and structures using spectral data
JPH04254760A (ja) 1991-01-30 1992-09-10 Eiken Chem Co Ltd 血清アミロイドa標準物質、およびその設定方法
US5221628A (en) 1991-03-19 1993-06-22 Northwestern University Binding of aggregated immunoglobulin or immune complexes by serum amyloid P component
RU2012877C1 (ru) 1991-04-01 1994-05-15 Белорусский научно-исследовательский институт охраны материнства и детства Способ прогнозирования синдрома дыхательных расстройств у недоношенных новорожденных
DE69122752T2 (de) 1991-08-02 1997-04-10 Grifols Grupo Sa Verfahren und Vorrichtung zur Bestimmung der Gerinnungszeit von Blut und Plasma
JPH0559415A (ja) * 1991-09-02 1993-03-09 Kobe Steel Ltd 高炉炉熱変化推定装置
WO1993007491A1 (en) 1991-10-04 1993-04-15 Board Of Regents Of The University Of Nebraska A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins
US5716795A (en) 1991-10-04 1998-02-10 Matschiner; John T. Thrombomodulin-based coagulometric assay of the protein C system
CA2121680C (en) 1991-11-04 2005-03-22 Andrew E. Senyei Screening method for identifying women at increased risk for preterm delivery
JPH05180835A (ja) 1991-12-27 1993-07-23 S R L:Kk ループスアンチコアグラントの測定方法
US5318958A (en) 1992-05-29 1994-06-07 Queen's University At Kingston Amyloid precursor protein
JP2934557B2 (ja) 1992-07-10 1999-08-16 国際試薬株式会社 血液凝固時間測定方法とその装置
JPH0636061A (ja) 1992-07-21 1994-02-10 Fujitsu Ltd 階層型ニューラルネットワークの学習方式
DE4224621C2 (de) * 1992-07-25 1994-05-05 Boehringer Mannheim Gmbh Verfahren zur Analyse eines Bestandteils einer medizinischen Probe mittels eines automatischen Analysegerätes
US5388164A (en) 1992-08-19 1995-02-07 Olympus Optical Co., Ltd. Method for judging particle agglutination patterns using neural networks
JP3224607B2 (ja) 1992-09-11 2001-11-05 株式会社アズウェル 血液凝固第xiii因子活性測定方法および該測定用試薬キット
US5369484A (en) 1992-11-09 1994-11-29 Akzo N.V. Multiple discrete analyzer test apparatus and method
US5358852A (en) 1992-12-21 1994-10-25 Eastman Kodak Company Use of calcium in immunoassay for measurement of C-reactive protein
RU2070327C1 (ru) 1992-12-25 1996-12-10 Безруков Александр Васильевич Устройство для измерения времени свертывания крови
US5344754A (en) 1993-01-13 1994-09-06 Avocet Medical, Inc. Assay timed by electrical resistance change and test strip
JP2938302B2 (ja) 1993-02-25 1999-08-23 国際試薬株式会社 血液凝固時間測定方法とその装置
JPH06249857A (ja) 1993-02-26 1994-09-09 Hitachi Ltd 自動分析装置
RU2061953C1 (ru) 1993-03-10 1996-06-10 Тюменский государственный медицинский институт МЗ РФ Способ количественного определения общей коагуляционной активности тромбоцитов
US5670329A (en) 1993-05-28 1997-09-23 Cardiovascular Diagnostics, Inc. Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field
AU688365B2 (en) 1993-08-16 1998-03-12 Biomerieux, Inc. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
US5526111A (en) 1993-08-31 1996-06-11 Boehringer Mannheim Corporation Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
US5472852A (en) 1993-09-15 1995-12-05 Oklahoma Medical Research Foundation Assay for detection of selective Protein C inhibition by patients
US5473732A (en) 1993-11-02 1995-12-05 Chang; Hou-Mei H. Relational artificial intelligence system
US5553616A (en) 1993-11-30 1996-09-10 Florida Institute Of Technology Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator
US5856114A (en) * 1994-03-21 1999-01-05 The University Of Vermont Immunologic detection of factor VA fragments in hemorrhagic and thrombotic clinical settings
ATE202633T1 (de) 1994-04-28 2001-07-15 Dade Behring Inc Kalibrator für prothrombin-zeit-assays
AU1287595A (en) 1994-08-26 1996-03-22 Immtech International, Inc. A mutant protein and methods and materials for making and using it
US5504011A (en) 1994-10-21 1996-04-02 International Technidyne Corporation Portable test apparatus and associated method of performing a blood coagulation test
SE9403833D0 (sv) 1994-11-08 1994-11-08 Global Hemostasis Inst Mgr Ab Analysförfarande och kit
US5705395A (en) * 1994-11-14 1998-01-06 The Scripps Research Institute Method for diagnosis of thrombotic disorders
US5567596A (en) 1994-12-29 1996-10-22 Research Foundation Of State University Of New York Rapid assay of activators and inhibitors of clotting
AU4634896A (en) 1995-01-10 1996-07-31 Hendrik Coenraad Hemker Methods of determining endogenous thrombin potential (etp) and thrombin substrates for use in said methods
US5708591A (en) 1995-02-14 1998-01-13 Akzo Nobel N.V. Method and apparatus for predicting the presence of congenital and acquired imbalances and therapeutic conditions
US6321164B1 (en) 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
US5780255A (en) 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test
AU711163B2 (en) 1995-07-21 1999-10-07 Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin, The Method for the quantitative measurement of human acute phase serum amyloid a protein; recombinant protein; specific antibody
US5766869A (en) 1995-11-30 1998-06-16 Ahs Hospital Corp. Factor V ratio blood test for susceptibility to thromboembolism
JP3743918B2 (ja) 1996-03-22 2006-02-08 デイド、ベーリング、インコーポレイテッド コンビネーション試薬保持およびテスト装置
JPH1026621A (ja) 1996-07-12 1998-01-27 Dai Ichi Pure Chem Co Ltd イムノアッセイ法
US5684007A (en) 1996-09-05 1997-11-04 Otsuka Pharmaceutical Co., Ltd. Methods for inhibiting cardiac fibroblast growth and cardiac fibrosis
JP3876022B2 (ja) 1996-09-26 2007-01-31 生化学工業株式会社 血液凝固時間に影響を与える物質の定量方法
US5981285A (en) 1996-10-21 1999-11-09 Carroll; Wallace E. Method and apparatus for determining anticoagulant therapy factors
EP0841566A1 (en) 1996-11-11 1998-05-13 Pentapharm A.G. Positive control plasma for lupus anticoagulant
WO1998043630A1 (en) 1997-04-02 1998-10-08 Brigham And Women's Hospital, Inc. Means of ascertaining an individual's risk profile for atherosclerotic disease
US6010911A (en) 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
PT947585E (pt) 1998-03-19 2001-11-30 Instrumentation Lab Spa Metodo in vitro melhorado, kits e reagentes para a peaquisa de defeitos de coagulacao sanguinea

Also Published As

Publication number Publication date
US6502040B2 (en) 2002-12-31
WO2001001152A1 (en) 2001-01-04
ES2270850T3 (es) 2007-04-16
CA2377528A1 (en) 2001-01-04
KR20020042539A (ko) 2002-06-05
EP1188060A4 (en) 2005-04-13
AU768436B2 (en) 2003-12-11
EP1188060A1 (en) 2002-03-20
JP2003529046A (ja) 2003-09-30
ATE328327T1 (de) 2006-06-15
AU6067600A (en) 2001-01-31
US20020010553A1 (en) 2002-01-24
DE60028374D1 (de) 2006-07-06
EP1188060B1 (en) 2006-05-31
WO2001001152A9 (en) 2002-05-02
DE60028374T2 (de) 2007-06-06

Similar Documents

Publication Publication Date Title
Yang et al. Prothrombin time
CA2316361C (en) A method for predicting an abnormal level of clotting proteins
EP0834145B1 (en) A method and apparatus for predicting the presence of congenital and acquired imbalances and therapeutic conditions
Podda et al. Usefulness of PFA‐100® testing in the diagnostic screening of patients with suspected abnormalities of hemostasis: comparison with the bleeding time
AU774889B2 (en) A method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US20130344519A1 (en) Methods and systems for assessment of turbidity kinetics (waveform analysis) in coagulation testing
US6898532B1 (en) Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
de Laat-Kremers et al. Deciphered coagulation profile to diagnose the antiphospholipid syndrome using artificial intelligence
CA2377528C (en) Method and apparatus for presenting thrombosis and hemostasis assay data
Joist Hypercoagulability: introduction and perspective
Fricke et al. A multicenter clinical evaluation of the Clot Signature Analyzer
Perifanis et al. Update on laboratory testing and hemostasis assessment in patients receiving direct oral anticoagulants (DOACs)
AU2004201011B2 (en) Method and apparatus for presenting thrombosis and hemostasis assay data
US20090191637A1 (en) Method and apparatus for determining anticoagulant therapy factors
Givens et al. Classification of factor deficiencies from coagulation assays using neural networks
EP1907866B1 (en) Method and apparatus for determining anticoagulant therapy factors
Mirus et al. Effects of pneumatic tube systems on viscoelastic coagulation tests in septic patients and healthy individuals: protocol of the randomized controlled VETaPT-trial
Marlar Hemostasis test validation, performance and reference intervals
Alfaraj et al. Accurate Laboratory Detection of Lupus Anticoagulant in Anticoagulated Patients: An Area for Adopting System based Collaboration in Thrombosis
Sorrentino et al. Measuring Direct Oral Anticoagulant Levels in Laboratory Practice: Impact of Different Storage Conditions of Blood Samples
EP1522860A1 (en) A method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
Artang et al. TH Open
Cook et al. Laboratory Instrumentation, Reagents, Methods, and Patient Sample as Variables in Coagulation
Kammerer et al. Simon T. Schäfer1, Anne-Christine Otto1, Alice-Christin Acevedo1, Klaus Görlinger2, Steffen Massberg3

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20200630