FR2364453A1 - Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate - Google Patents
Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalateInfo
- Publication number
- FR2364453A1 FR2364453A1 FR7627422A FR7627422A FR2364453A1 FR 2364453 A1 FR2364453 A1 FR 2364453A1 FR 7627422 A FR7627422 A FR 7627422A FR 7627422 A FR7627422 A FR 7627422A FR 2364453 A1 FR2364453 A1 FR 2364453A1
- Authority
- FR
- France
- Prior art keywords
- coagulation time
- oxalated
- optical density
- measurement
- plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La présente invention a pour objet un dispositif électronique permettant la mesure, par un procédé optique, du temps de formation d'un caillot de plasma sanguin, sous l'action de divers réactifs notamment calciques, que l'anticoagulant utilisé lors du prélèvement soit un citrate ou un oxalate. La caractéristique principale du système réside en ce que l'examen de la succession des changements de signe des deuxième et troisième dérivées, par rapport au temps, de la densité optique du mélange plasma-réactif permet une mesure effective du temps de coagulation, malgré la difficulté causée par l'apparition d'un précipité d'oxalate de calcium, qui masque partiellement la variation de densité optique due à la coagulation à examiner. L'invention permet la réalisation d'un prothrombinomètre simple à variation de densité optique, analysant divers facteurs intervenant dans la coagulation sanguine, et fonctionnant quel que soit l'anticoagulant utilisé lors du prélèvement
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7627422A FR2364453A1 (fr) | 1976-09-08 | 1976-09-08 | Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7627422A FR2364453A1 (fr) | 1976-09-08 | 1976-09-08 | Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2364453A1 true FR2364453A1 (fr) | 1978-04-07 |
Family
ID=9177606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7627422A Withdrawn FR2364453A1 (fr) | 1976-09-08 | 1976-09-08 | Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2364453A1 (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2408839A1 (fr) * | 1977-11-12 | 1979-06-08 | Kyoto Daiichi Kagaku Kk | Procede et appareil pour mesurer la lumiere diffusee par du plasma sanguin afin de determiner le temps de coagulation de ce sang |
US6101449A (en) * | 1995-06-07 | 2000-08-08 | Akzo Nobel N.V. | Method for predicting the presence of congenital and therapeutic conditions from coagulation screening assays |
US6321164B1 (en) | 1995-06-07 | 2001-11-20 | Akzo Nobel N.V. | Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade |
US6429017B1 (en) | 1999-02-04 | 2002-08-06 | Biomerieux | Method for predicting the presence of haemostatic dysfunction in a patient sample |
US6502040B2 (en) | 1997-12-31 | 2002-12-31 | Biomerieux, Inc. | Method for presenting thrombosis and hemostasis assay data |
US6898532B1 (en) | 1995-06-07 | 2005-05-24 | Biomerieux, Inc. | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
US7179612B2 (en) | 2000-06-09 | 2007-02-20 | Biomerieux, Inc. | Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality |
US7211438B2 (en) | 1999-02-04 | 2007-05-01 | Biomerieux, Inc. | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
-
1976
- 1976-09-08 FR FR7627422A patent/FR2364453A1/fr not_active Withdrawn
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2408839A1 (fr) * | 1977-11-12 | 1979-06-08 | Kyoto Daiichi Kagaku Kk | Procede et appareil pour mesurer la lumiere diffusee par du plasma sanguin afin de determiner le temps de coagulation de ce sang |
US6101449A (en) * | 1995-06-07 | 2000-08-08 | Akzo Nobel N.V. | Method for predicting the presence of congenital and therapeutic conditions from coagulation screening assays |
US6269313B1 (en) | 1995-06-07 | 2001-07-31 | Akzo Nobel N.V. | Method for predicting the presence of congenital and therapeutic conditions from coagulation screening assays |
US6321164B1 (en) | 1995-06-07 | 2001-11-20 | Akzo Nobel N.V. | Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade |
US6564153B2 (en) | 1995-06-07 | 2003-05-13 | Biomerieux | Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade |
US6898532B1 (en) | 1995-06-07 | 2005-05-24 | Biomerieux, Inc. | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
US6502040B2 (en) | 1997-12-31 | 2002-12-31 | Biomerieux, Inc. | Method for presenting thrombosis and hemostasis assay data |
US6429017B1 (en) | 1999-02-04 | 2002-08-06 | Biomerieux | Method for predicting the presence of haemostatic dysfunction in a patient sample |
US7211438B2 (en) | 1999-02-04 | 2007-05-01 | Biomerieux, Inc. | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
US7179612B2 (en) | 2000-06-09 | 2007-02-20 | Biomerieux, Inc. | Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |