DE69607176T2 - Verfahren zur quantitativen bestimmung menschlichen akutphasen-serum-amyloid-a-proteins; rekombinantes protein; spezifischer antikörper - Google Patents

Verfahren zur quantitativen bestimmung menschlichen akutphasen-serum-amyloid-a-proteins; rekombinantes protein; spezifischer antikörper

Info

Publication number
DE69607176T2
DE69607176T2 DE69607176T DE69607176T DE69607176T2 DE 69607176 T2 DE69607176 T2 DE 69607176T2 DE 69607176 T DE69607176 T DE 69607176T DE 69607176 T DE69607176 T DE 69607176T DE 69607176 T2 DE69607176 T2 DE 69607176T2
Authority
DE
Germany
Prior art keywords
serum amyloid
proteins
acute phase
human acute
saa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69607176T
Other languages
English (en)
Other versions
DE69607176D1 (de
Inventor
John Martin Doyle
Hazel Audrey Hobson
Alexander Steven Whitehead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Original Assignee
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin filed Critical College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Publication of DE69607176D1 publication Critical patent/DE69607176D1/de
Application granted granted Critical
Publication of DE69607176T2 publication Critical patent/DE69607176T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69607176T 1995-07-21 1996-07-19 Verfahren zur quantitativen bestimmung menschlichen akutphasen-serum-amyloid-a-proteins; rekombinantes protein; spezifischer antikörper Expired - Fee Related DE69607176T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE950553 1995-07-21
PCT/IE1996/000042 WO1997004317A1 (en) 1995-07-21 1996-07-19 Method for the quantitative measurement of human acute phase serum amyloid a protein; recombinant protein; specific antibody

Publications (2)

Publication Number Publication Date
DE69607176D1 DE69607176D1 (de) 2000-04-20
DE69607176T2 true DE69607176T2 (de) 2000-09-21

Family

ID=11040829

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69607176T Expired - Fee Related DE69607176T2 (de) 1995-07-21 1996-07-19 Verfahren zur quantitativen bestimmung menschlichen akutphasen-serum-amyloid-a-proteins; rekombinantes protein; spezifischer antikörper

Country Status (9)

Country Link
US (1) US6194163B1 (de)
EP (1) EP0842434B1 (de)
JP (1) JPH11510596A (de)
AT (1) ATE190728T1 (de)
AU (1) AU711163B2 (de)
BR (1) BR9609771A (de)
CA (1) CA2227537A1 (de)
DE (1) DE69607176T2 (de)
WO (1) WO1997004317A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6898532B1 (en) 1995-06-07 2005-05-24 Biomerieux, Inc. Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6429017B1 (en) 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
US6321164B1 (en) 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
US6502040B2 (en) 1997-12-31 2002-12-31 Biomerieux, Inc. Method for presenting thrombosis and hemostasis assay data
JP4486260B2 (ja) 1999-02-04 2010-06-23 バイオメリュー・インコーポレイテッド 患者サンプルにおける止血機能不全の存在を予測するための方法および装置
US6251624B1 (en) 1999-03-12 2001-06-26 Akzo Nobel N.V. Apparatus and method for detecting, quantifying and characterizing microorganisms
JP3511023B2 (ja) 1999-08-25 2004-03-29 アキュプレックス，リミティド ライアビリティーカンパニー 感染及び炎症状態の検出のための分泌された生物学的流体の診断アッセイ
EP1222275A2 (de) 1999-10-22 2002-07-17 The Board of Regents of the University of Nebraska Serum amyloid a isoform aus colostrum
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
AU2002230997A1 (en) * 2000-12-15 2002-06-24 Genetics Institute, Llc Methods and compositions for diagnosing and treating rheumatoid arthritis
CA2438137A1 (en) * 2001-02-13 2002-08-22 Universiteit Gent Device and method for detecting the presence of an analyte
US6815175B2 (en) * 2001-03-16 2004-11-09 Cornell Research Foundation, Inc. Anti-amyloid peptide antibody based diagnosis and treatment of a neurological disease or disorder
US20020160533A1 (en) * 2001-04-30 2002-10-31 George Jackowski Biopolymer marker indicative of disease state having a molecular of weight of 1525 daltons
US20040203031A1 (en) 2002-04-03 2004-10-14 University Of Pennsylvania Methods for determining drug responsiveness
US20040072181A1 (en) 2002-01-22 2004-04-15 Whitehead Alexander Steven Methods for determining drug responsiveness
US7368546B2 (en) 2003-01-21 2008-05-06 The Board Of Regents Of The University Of Nebraska Human SAA3 nucleic acid molecule, protein, and methods of use for same
WO2006063213A2 (en) * 2004-12-10 2006-06-15 University Of Maryland, Baltimore Serum amyloid a protein in inflammation and obesity
EP1943359B1 (de) * 2005-09-30 2011-06-29 Centocor Ortho Biotech Inc. Zusammensetzungen und verfahren für il13-biomarker
EP2730659A3 (de) 2007-12-28 2016-01-13 Prothena Biosciences Limited Behandlung und Prophylaxe von Amyloidose
CA3226224A1 (en) * 2013-02-04 2014-08-07 Epona Biotech Ltd Device and diagnostic methods for infections in mammals using serum amyloid a
CN106053862B (zh) * 2016-05-16 2017-09-15 河北艾驰生物科技有限公司 血清淀粉样蛋白a（saa）测定试剂盒
CN106198961A (zh) * 2016-07-21 2016-12-07 上海奥普生物医药有限公司 一种定量检测血清淀粉样蛋白a的乳胶增强免疫比浊试剂盒及其制备方法
CN108680751A (zh) * 2018-04-04 2018-10-19 苏州遵道生物科技有限公司 定量检测血清淀粉样蛋白a的时间分辨荧光免疫层析试纸条及其制备方法
CN113189335A (zh) * 2021-06-17 2021-07-30 上海中乔新舟生物科技有限公司 血清淀粉样蛋白a2在制备检测肺癌试剂盒中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE500044C2 (sv) * 1985-02-15 1994-03-28 Gambro Lundia Ab Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen
GB8516081D0 (en) * 1985-06-25 1985-07-31 Ciba Geigy Ag Assay & purification of amyloid components
JPS6344895A (ja) * 1986-08-13 1988-02-25 Kyowa Hakko Kogyo Co Ltd 抗アミロイドａ蛋白質単クロ−ン性抗体
US5126240A (en) * 1986-09-29 1992-06-30 Curtiss Linda K Hybridomas and monoclonal paratopic molecules to apolipoprotein a-i
US5262303A (en) * 1989-10-13 1993-11-16 Trustees Of Boston University Ligand/anti-ligand assays for adherent proteins
US5290686A (en) * 1991-07-31 1994-03-01 The United States Of America As Represented By The Department Of Health And Human Services Expression of influenza a M2 protein in baculovirus
JPH08178921A (ja) * 1994-12-21 1996-07-12 Cosmo Sogo Kenkyusho:Kk 血清アミロイドａの免疫学的測定方法

Also Published As

Publication number Publication date
JPH11510596A (ja) 1999-09-14
BR9609771A (pt) 1999-12-21
DE69607176D1 (de) 2000-04-20
AU711163B2 (en) 1999-10-07
ATE190728T1 (de) 2000-04-15
EP0842434B1 (de) 2000-03-15
US6194163B1 (en) 2001-02-27
WO1997004317A1 (en) 1997-02-06
EP0842434A1 (de) 1998-05-20
CA2227537A1 (en) 1997-02-06
AU6667096A (en) 1997-02-18

Similar Documents

Publication Publication Date Title
DE69607176T2 (de) Verfahren zur quantitativen bestimmung menschlichen akutphasen-serum-amyloid-a-proteins; rekombinantes protein; spezifischer antikörper
NO20000970L (no) Fremgangsmõte og utstyr for rask analyse av analytter i biologiske stikkprøver
KR930022086A (ko) 아밀로이드 전구체 단백질의 단백질가수분해에 근거한 알츠하이머병(Alzheimer's disease)의 진단분석
ATE226729T1 (de) Quantitative immunochromatographische assays
DE60024448D1 (de) System zur elektrochemischen quantitativen analyse von analyten in einer festphase
WO2001025788A1 (en) Non-separation heterogenous assay for biological substances
KR100394940B1 (ko) 간 질환 진단을 위한 혈중 아사이알로당단백질양의측정방법 및 측정용 킷트
Chen Characterization of charge-modified and fluorescein-labeled antibody by capillary electrophoresis using laser-induced fluorescence Application to immunoassay of low level immunoglobulin A
JP3848416B2 (ja) 質量感受性バイオセンサー
Gardies et al. Feasibility of an immunosensor based upon capacitance measurements
US7067264B2 (en) Test device for detecting human blood and method of use
Phillips Determination of in situ tissue neuropeptides by capillary immunoelectrophoresis
KR20160120675A (ko) 래피드 정량 진단 키트
ES2159291T3 (es) Metodo y analisis de htlv-i/htlv-ii.
NZ334809A (en) Assay for the detection of antibodies against p53
EP1166113A1 (de) Lipopoysaccharid-immunoassay und testvorrichtung
WO1995002822A1 (en) Test device
JP2760335B2 (ja) タンパク質センサ
US6168921B1 (en) Method for the quantitative and/or qualitative determination of atoms or molecules
CA2213083A1 (en) Detection of antibody production
CN103630692A (zh) 快速检测尿液c肽的胶体金免疫层析试剂盒及其检测方法
NISHIMURA et al. Enzyme immunoassay for manganese-superoxide dismutase in serum and urine
WO2001027621A3 (en) Competitive inhibition elisa for antibody detection
KR101187674B1 (ko) 이단 면역 크로마토그래피를 이용한 효소 활성 측정법
US20050118728A1 (en) Two-layer antibody capture system

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee