CA2348745A1 - Dna molecules encoding muc-1 and use thereof in tumor vaccination - Google Patents
Dna molecules encoding muc-1 and use thereof in tumor vaccination Download PDFInfo
- Publication number
- CA2348745A1 CA2348745A1 CA002348745A CA2348745A CA2348745A1 CA 2348745 A1 CA2348745 A1 CA 2348745A1 CA 002348745 A CA002348745 A CA 002348745A CA 2348745 A CA2348745 A CA 2348745A CA 2348745 A1 CA2348745 A1 CA 2348745A1
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- Prior art keywords
- sequence
- dna
- fragment
- muc
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 238000002255 vaccination Methods 0.000 title description 10
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4727—Mucins, e.g. human intestinal mucin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI98A002330 | 1998-10-30 | ||
| IT1998MI002330A IT1303683B1 (it) | 1998-10-30 | 1998-10-30 | Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica. |
| PCT/EP1999/007874 WO2000025827A2 (en) | 1998-10-30 | 1999-10-18 | Dna molecules encoding muc-1 and use thereof in tumor vaccination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2348745A1 true CA2348745A1 (en) | 2000-05-11 |
Family
ID=11380969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002348745A Abandoned CA2348745A1 (en) | 1998-10-30 | 1999-10-18 | Dna molecules encoding muc-1 and use thereof in tumor vaccination |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1124956A2 (it) |
| JP (1) | JP2002528519A (it) |
| CN (1) | CN1324406A (it) |
| AR (1) | AR020927A1 (it) |
| AU (1) | AU1152200A (it) |
| BG (1) | BG105458A (it) |
| BR (1) | BR9914892A (it) |
| CA (1) | CA2348745A1 (it) |
| CO (1) | CO5231134A1 (it) |
| CZ (1) | CZ20011521A3 (it) |
| EA (1) | EA200100395A1 (it) |
| HU (1) | HUP0103784A2 (it) |
| IT (1) | IT1303683B1 (it) |
| MX (1) | MXPA01004186A (it) |
| PE (1) | PE20001287A1 (it) |
| PL (1) | PL348156A1 (it) |
| SK (1) | SK5712001A3 (it) |
| TR (1) | TR200101141T2 (it) |
| WO (1) | WO2000025827A2 (it) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6548643B1 (en) | 1994-11-16 | 2003-04-15 | Austin Research Institute | Antigen carbohydrate compounds and their use in immunotherapy |
| EP1257565A4 (en) * | 2000-02-01 | 2005-04-06 | Austin Research Inst | DERIVED FROM MUCIN-1 ANTIGENE AND ITS USE IN IMMUNOTHERAPY |
| WO2002022685A2 (en) * | 2000-09-11 | 2002-03-21 | Kufe Donald W | Muc1 extracellular domain and cancer treatment compositions and methods derived therefrom |
| JP4276432B2 (ja) | 2000-12-22 | 2009-06-10 | ダナ−ファーバー キャンサー インスティテュート，インコーポレイテッド | Ｍｕｃ１による細胞増殖調節方法 |
| WO2004099389A2 (en) * | 2003-03-24 | 2004-11-18 | The Scripps Research Institute | Dna vaccines against tumor growth and methods of use thereof |
| US7696306B2 (en) | 2003-07-11 | 2010-04-13 | Board of Agents of the University of Nebraska | Compositions and methods for preventing or treating cancer |
| WO2005042573A1 (en) * | 2003-10-24 | 2005-05-12 | Dana-Farber Cancer Institute, Inc. | Modulation of the interaction of muc1 with muc1 ligands |
| WO2008097840A2 (en) | 2007-02-02 | 2008-08-14 | Dana-Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of muc1 by hsf1 and stat3 |
| WO2008097844A2 (en) | 2007-02-02 | 2008-08-14 | Dana -Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of apoptosis by muc1 and bh3- containing proapoptotic proteins |
| CN106279435B (zh) * | 2016-08-16 | 2019-06-07 | 新乡医学院 | 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用 |
| CN114230656A (zh) * | 2021-03-24 | 2022-03-25 | 深圳市新靶向生物科技有限公司 | 一种与食道癌驱动基因突变相关的抗原肽组合及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1262545B (it) * | 1993-10-25 | 1996-07-02 | Menarini Ricerche Sud S P A A | Sistema di espressione per linee cellulari eucariotiche |
| CA2282300C (en) * | 1997-02-24 | 2011-08-02 | Therion Biologics Corporation | Recombinant pox virus for immunization against muc1 tumor-associated antigen |
-
1998
- 1998-10-30 IT IT1998MI002330A patent/IT1303683B1/it active
-
1999
- 1999-10-18 TR TR2001/01141T patent/TR200101141T2/xx unknown
- 1999-10-18 JP JP2000579265A patent/JP2002528519A/ja active Pending
- 1999-10-18 HU HU0103784A patent/HUP0103784A2/hu unknown
- 1999-10-18 WO PCT/EP1999/007874 patent/WO2000025827A2/en not_active Application Discontinuation
- 1999-10-18 CZ CZ20011521A patent/CZ20011521A3/cs unknown
- 1999-10-18 EP EP99971329A patent/EP1124956A2/en not_active Withdrawn
- 1999-10-18 AU AU11522/00A patent/AU1152200A/en not_active Abandoned
- 1999-10-18 MX MXPA01004186A patent/MXPA01004186A/es unknown
- 1999-10-18 CA CA002348745A patent/CA2348745A1/en not_active Abandoned
- 1999-10-18 CN CN99812745A patent/CN1324406A/zh active Pending
- 1999-10-18 BR BR9914892-7A patent/BR9914892A/pt not_active IP Right Cessation
- 1999-10-18 EA EA200100395A patent/EA200100395A1/ru unknown
- 1999-10-18 SK SK571-2001A patent/SK5712001A3/sk unknown
- 1999-10-18 PL PL99348156A patent/PL348156A1/xx unknown
- 1999-10-21 AR ARP990105316A patent/AR020927A1/es unknown
- 1999-10-22 PE PE1999001068A patent/PE20001287A1/es not_active Application Discontinuation
- 1999-10-29 CO CO99068636A patent/CO5231134A1/es not_active Application Discontinuation
-
2001
- 2001-04-20 BG BG105458A patent/BG105458A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002528519A (ja) | 2002-09-03 |
| EA200100395A1 (ru) | 2001-10-22 |
| EP1124956A2 (en) | 2001-08-22 |
| CO5231134A1 (es) | 2002-12-27 |
| IT1303683B1 (it) | 2001-02-23 |
| BR9914892A (pt) | 2001-07-17 |
| BG105458A (en) | 2002-06-28 |
| HUP0103784A2 (hu) | 2002-02-28 |
| ITMI982330A1 (it) | 2000-04-30 |
| MXPA01004186A (es) | 2002-06-04 |
| ITMI982330A0 (it) | 1998-10-30 |
| PE20001287A1 (es) | 2000-12-07 |
| CN1324406A (zh) | 2001-11-28 |
| SK5712001A3 (en) | 2002-04-04 |
| WO2000025827A3 (en) | 2000-08-10 |
| TR200101141T2 (tr) | 2001-09-21 |
| AU1152200A (en) | 2000-05-22 |
| CZ20011521A3 (cs) | 2001-10-17 |
| PL348156A1 (en) | 2002-05-06 |
| WO2000025827A2 (en) | 2000-05-11 |
| AR020927A1 (es) | 2002-06-05 |
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| FZDE | Discontinued |