TR200101141T2 - Antitümör etkiyi haiz antijenik proteini şifreleyen bir DNA'ya mahsus parçalar ihtiva eden farmasötik bileşim - Google Patents

Antitümör etkiyi haiz antijenik proteini şifreleyen bir DNA'ya mahsus parçalar ihtiva eden farmasötik bileşim

Info

Publication number
TR200101141T2
TR200101141T2 TR2001/01141T TR200101141T TR200101141T2 TR 200101141 T2 TR200101141 T2 TR 200101141T2 TR 2001/01141 T TR2001/01141 T TR 2001/01141T TR 200101141 T TR200101141 T TR 200101141T TR 200101141 T2 TR200101141 T2 TR 200101141T2
Authority
TR
Turkey
Prior art keywords
pharmaceutical composition
composition containing
dna encoding
antitumor effect
antigenic protein
Prior art date
Application number
TR2001/01141T
Other languages
English (en)
Inventor
Parente Dino
Maria Di Massimo Anna
De Santis Rita
Original Assignee
Menarini Ricerche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.
Publication of TR200101141T2 publication Critical patent/TR200101141T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001136—Cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Isbu metinde, bir antitümör Ag-spesifik immün yaniti indüklemek amaciyla uygun eksipiyan ve ilave maddelerle birlikte, tümör hücrelerinde asiri eksprese olan bir proteine mahsus parçalari sifreleyen bir veya daha fazla DNA molekülünü ihtiva eden farmasötik bir bilesim sunulmaktadir.
TR2001/01141T 1998-10-30 1999-10-18 Antitümör etkiyi haiz antijenik proteini şifreleyen bir DNA'ya mahsus parçalar ihtiva eden farmasötik bileşim TR200101141T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.

Publications (1)

Publication Number Publication Date
TR200101141T2 true TR200101141T2 (tr) 2001-09-21

Family

ID=11380969

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01141T TR200101141T2 (tr) 1998-10-30 1999-10-18 Antitümör etkiyi haiz antijenik proteini şifreleyen bir DNA'ya mahsus parçalar ihtiva eden farmasötik bileşim

Country Status (19)

Country Link
EP (1) EP1124956A2 (tr)
JP (1) JP2002528519A (tr)
CN (1) CN1324406A (tr)
AR (1) AR020927A1 (tr)
AU (1) AU1152200A (tr)
BG (1) BG105458A (tr)
BR (1) BR9914892A (tr)
CA (1) CA2348745A1 (tr)
CO (1) CO5231134A1 (tr)
CZ (1) CZ20011521A3 (tr)
EA (1) EA200100395A1 (tr)
HU (1) HUP0103784A2 (tr)
IT (1) IT1303683B1 (tr)
MX (1) MXPA01004186A (tr)
PE (1) PE20001287A1 (tr)
PL (1) PL348156A1 (tr)
SK (1) SK5712001A3 (tr)
TR (1) TR200101141T2 (tr)
WO (1) WO2000025827A2 (tr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548643B1 (en) 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
EP1257565A4 (en) * 2000-02-01 2005-04-06 Austin Research Inst DERIVED FROM MUCIN-1 ANTIGENE AND ITS USE IN IMMUNOTHERAPY
KR20030068536A (ko) * 2000-09-11 2003-08-21 다나-파버 캔서 인스티튜트 Ｍｕｃ1 세포외 도메인 및 이로부터 유래된 암 치료조성물과 방법
WO2002058450A2 (en) 2000-12-22 2002-08-01 Dana-Faber Cancer Institute, Inc. Regulation of cell growth by muc1
AU2004236636B2 (en) * 2003-03-24 2010-02-04 The Scripps Research Institute DNA vaccines against tumor growth and methods of use thereof
US7696306B2 (en) * 2003-07-11 2010-04-13 Board of Agents of the University of Nebraska Compositions and methods for preventing or treating cancer
US8129506B2 (en) 2003-10-24 2012-03-06 Genzyme Corporation Modulation of the interaction of MUC1 with MUC1 ligands
US7972870B2 (en) 2007-02-02 2011-07-05 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3
WO2008097844A2 (en) 2007-02-02 2008-08-14 Dana -Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of apoptosis by muc1 and bh3- containing proapoptotic proteins
CN106279435B (zh) * 2016-08-16 2019-06-07 新乡医学院 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用
CN114230656A (zh) * 2021-03-24 2022-03-25 深圳市新靶向生物科技有限公司 一种与食道癌驱动基因突变相关的抗原肽组合及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262545B (it) * 1993-10-25 1996-07-02 Menarini Ricerche Sud S P A A Sistema di espressione per linee cellulari eucariotiche
EP1012276A2 (en) * 1997-02-24 2000-06-28 Therion Biologics Corporation Recombinant pox virus for immunization against muc1 tumor-associated antigen

Also Published As

Publication number Publication date
ITMI982330A1 (it) 2000-04-30
PL348156A1 (en) 2002-05-06
SK5712001A3 (en) 2002-04-04
BR9914892A (pt) 2001-07-17
EA200100395A1 (ru) 2001-10-22
CA2348745A1 (en) 2000-05-11
CN1324406A (zh) 2001-11-28
AU1152200A (en) 2000-05-22
CO5231134A1 (es) 2002-12-27
EP1124956A2 (en) 2001-08-22
MXPA01004186A (es) 2002-06-04
WO2000025827A3 (en) 2000-08-10
BG105458A (en) 2002-06-28
JP2002528519A (ja) 2002-09-03
PE20001287A1 (es) 2000-12-07
WO2000025827A2 (en) 2000-05-11
IT1303683B1 (it) 2001-02-23
ITMI982330A0 (it) 1998-10-30
HUP0103784A2 (hu) 2002-02-28
AR020927A1 (es) 2002-06-05
CZ20011521A3 (cs) 2001-10-17

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