CY1113064T1 - Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου - Google Patents

Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου

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Publication number
CY1113064T1
CY1113064T1 CY20111100824T CY111100824T CY1113064T1 CY 1113064 T1 CY1113064 T1 CY 1113064T1 CY 20111100824 T CY20111100824 T CY 20111100824T CY 111100824 T CY111100824 T CY 111100824T CY 1113064 T1 CY1113064 T1 CY 1113064T1
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CY
Cyprus
Prior art keywords
title
useful
detection
cancer treatment
corresponding protein
Prior art date
Application number
CY20111100824T
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English (en)
Inventor
Pia M Chalitta-Eid
Arthur B Raitano
Mary Faris
Rene S Hubert
Karen Morrison
Robert Kendall Morrison
Wangmao Ge
Aya Jakobovits
Original Assignee
Agensys, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Agensys, Inc. filed Critical Agensys, Inc.
Publication of CY1113064T1 publication Critical patent/CY1113064T1/el

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Περιγράφονται ένα νέο γονίδιο (που ορίζεται 184Ρ1Ε2) και η κωδικοποιημένη πρωτεΐνη του, και παραλλαγές αυτών, όπου το 184Ρ1Ε2 επιδεικνύει ιστοειδική έκφραση σε κανονικό ενήλικα ιστό, και εκφράζεται κατά παρέκκλιση στους καρκίνους που καταγράφονται στον Πίνακα I. Συνεπώς, το 184Ρ1Ε2 παρέχει έναν διαγνωστικό, προγνωστικό, προφυλακτικό ή/και θεραπευτικό στόχο για τον καρκίνο. Το γονίδιο 184Ρ1Ε2 ή θραύσμα αυτού, ή η κωδικοποιημένη πρωτεΐνη του, ή παραλλαγές αυτών, ή κάποιο θραύσμα αυτών, μπορούν να χρησιμοποιηθούν για να προκαλέσουν χυμική ή κυτταρική ανοσοαπόκριση, με τα αντισώματα ή Τ κύτταρα που είναι αντιδραστικά με το 184Ρ1Ε2 να μπορούν να χρησιμοποιηθούν στην ενεργή ή παθητική ανοσοποίηση.
CY20111100824T 2001-04-10 2011-08-30 Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου CY1113064T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28273901P 2001-04-10 2001-04-10
US28663001P 2001-04-25 2001-04-25
EP02731360A EP1573022B1 (en) 2001-04-10 2002-04-09 Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer

Publications (1)

Publication Number Publication Date
CY1113064T1 true CY1113064T1 (el) 2016-04-13

Family

ID=26961649

Family Applications (1)

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CY20111100824T CY1113064T1 (el) 2001-04-10 2011-08-30 Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου

Country Status (9)

Country Link
US (8) US20040062761A1 (el)
EP (1) EP1573022B1 (el)
AT (1) ATE512216T1 (el)
AU (1) AU2002303340A1 (el)
CA (1) CA2443147A1 (el)
CY (1) CY1113064T1 (el)
DK (1) DK1573022T3 (el)
PT (1) PT1573022E (el)
WO (2) WO2002083919A2 (el)

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DK1573022T3 (da) 2001-04-10 2011-09-12 Agensys Inc Nukleinsyre og tilsvarende protein betegnet 184P1E2, der er egnede til behandling og påvisning af cancer
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US20060128018A1 (en) * 2003-02-07 2006-06-15 Zwaka Thomas P Directed genetic modifications of human stem cells
US7585943B2 (en) 2005-04-20 2009-09-08 Viromed Co., Ltd. Compositions and methods for fusion protein separation
US20100203553A1 (en) * 2009-02-11 2010-08-12 Abdeen Suad M Histochemical and biomarker for liver fibrosis
US8449512B2 (en) 2010-04-09 2013-05-28 Davinci Biomedical Research Products Inc. Stoma stabilitating device and method
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US9889192B2 (en) 2012-10-01 2018-02-13 Thomas Jefferson University Immunization with rabies virus vector expressing foreign protein antigen
KR102369010B1 (ko) * 2013-08-27 2022-03-02 더 로얄 인스티튜션 포 디 어드밴스먼트 오브 러닝/맥길 유니버시티 연골 및 디스크 조직 병리들의 치료를 위한 방법들 및 조성물들

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Also Published As

Publication number Publication date
EP1573022A4 (en) 2008-01-09
EP1573022A2 (en) 2005-09-14
US20090264381A1 (en) 2009-10-22
US7879570B2 (en) 2011-02-01
WO2002083860A2 (en) 2002-10-24
US7135549B1 (en) 2006-11-14
US20110110952A1 (en) 2011-05-12
US20110123539A1 (en) 2011-05-26
AU2002303340A8 (en) 2007-08-30
DK1573022T3 (da) 2011-09-12
WO2002083860A9 (en) 2013-11-07
AU2002303340A1 (en) 2002-10-28
US7960527B2 (en) 2011-06-14
US20040062761A1 (en) 2004-04-01
US20100168214A1 (en) 2010-07-01
ATE512216T1 (de) 2011-06-15
WO2002083919A3 (en) 2007-06-28
PT1573022E (pt) 2011-08-23
US7592149B2 (en) 2009-09-22
US20070054284A1 (en) 2007-03-08
WO2002083919A2 (en) 2002-10-24
US20090148854A1 (en) 2009-06-11
EP1573022B1 (en) 2011-06-08
US7667015B2 (en) 2010-02-23
CA2443147A1 (en) 2002-10-24
US8168187B2 (en) 2012-05-01

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