CY1113064T1 - Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου - Google Patents
Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινουInfo
- Publication number
- CY1113064T1 CY1113064T1 CY20111100824T CY111100824T CY1113064T1 CY 1113064 T1 CY1113064 T1 CY 1113064T1 CY 20111100824 T CY20111100824 T CY 20111100824T CY 111100824 T CY111100824 T CY 111100824T CY 1113064 T1 CY1113064 T1 CY 1113064T1
- Authority
- CY
- Cyprus
- Prior art keywords
- title
- useful
- detection
- cancer treatment
- corresponding protein
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Περιγράφονται ένα νέο γονίδιο (που ορίζεται 184Ρ1Ε2) και η κωδικοποιημένη πρωτεΐνη του, και παραλλαγές αυτών, όπου το 184Ρ1Ε2 επιδεικνύει ιστοειδική έκφραση σε κανονικό ενήλικα ιστό, και εκφράζεται κατά παρέκκλιση στους καρκίνους που καταγράφονται στον Πίνακα I. Συνεπώς, το 184Ρ1Ε2 παρέχει έναν διαγνωστικό, προγνωστικό, προφυλακτικό ή/και θεραπευτικό στόχο για τον καρκίνο. Το γονίδιο 184Ρ1Ε2 ή θραύσμα αυτού, ή η κωδικοποιημένη πρωτεΐνη του, ή παραλλαγές αυτών, ή κάποιο θραύσμα αυτών, μπορούν να χρησιμοποιηθούν για να προκαλέσουν χυμική ή κυτταρική ανοσοαπόκριση, με τα αντισώματα ή Τ κύτταρα που είναι αντιδραστικά με το 184Ρ1Ε2 να μπορούν να χρησιμοποιηθούν στην ενεργή ή παθητική ανοσοποίηση.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28273901P | 2001-04-10 | 2001-04-10 | |
US28663001P | 2001-04-25 | 2001-04-25 | |
EP02731360A EP1573022B1 (en) | 2001-04-10 | 2002-04-09 | Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113064T1 true CY1113064T1 (el) | 2016-04-13 |
Family
ID=26961649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100824T CY1113064T1 (el) | 2001-04-10 | 2011-08-30 | Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου |
Country Status (9)
Country | Link |
---|---|
US (8) | US20040062761A1 (el) |
EP (1) | EP1573022B1 (el) |
AT (1) | ATE512216T1 (el) |
AU (1) | AU2002303340A1 (el) |
CA (1) | CA2443147A1 (el) |
CY (1) | CY1113064T1 (el) |
DK (1) | DK1573022T3 (el) |
PT (1) | PT1573022E (el) |
WO (2) | WO2002083919A2 (el) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1573022T3 (da) | 2001-04-10 | 2011-09-12 | Agensys Inc | Nukleinsyre og tilsvarende protein betegnet 184P1E2, der er egnede til behandling og påvisning af cancer |
TWI325003B (en) | 2002-07-23 | 2010-05-21 | Sod Conseils Rech Applic | Ghrelin analogs |
US20060128018A1 (en) * | 2003-02-07 | 2006-06-15 | Zwaka Thomas P | Directed genetic modifications of human stem cells |
US7585943B2 (en) | 2005-04-20 | 2009-09-08 | Viromed Co., Ltd. | Compositions and methods for fusion protein separation |
US20100203553A1 (en) * | 2009-02-11 | 2010-08-12 | Abdeen Suad M | Histochemical and biomarker for liver fibrosis |
US8449512B2 (en) | 2010-04-09 | 2013-05-28 | Davinci Biomedical Research Products Inc. | Stoma stabilitating device and method |
WO2012075411A1 (en) * | 2010-12-03 | 2012-06-07 | The Board Of Trustees Of The Leland Stanford Junior University | Quantitative aggregation sensors |
WO2013101611A1 (en) | 2011-12-30 | 2013-07-04 | Abbott Molecular Inc. | Materials and methods for diagnosis of bladder cancer and monitoring recurrence thereof |
US9889192B2 (en) | 2012-10-01 | 2018-02-13 | Thomas Jefferson University | Immunization with rabies virus vector expressing foreign protein antigen |
KR102369010B1 (ko) * | 2013-08-27 | 2022-03-02 | 더 로얄 인스티튜션 포 디 어드밴스먼트 오브 러닝/맥길 유니버시티 | 연골 및 디스크 조직 병리들의 치료를 위한 방법들 및 조성물들 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
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US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
US5976535A (en) * | 1992-06-09 | 1999-11-02 | Neorx Corporation | Pretargeting protocols for the enhanced localization of cytotoxins to target sites and cytotoxic combinations useful therefore |
US5872094A (en) * | 1993-01-06 | 1999-02-16 | The General Hospital Corporation | Method for attaching cartilaginous tissue, cartilage matrix protein or link protein to a surface |
WO1996009395A2 (de) | 1994-09-21 | 1996-03-28 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Arzneimittel zur prophylaxe und behandlung von und diagnostika zur erkennung von autoimmunkrankheiten und viralen erkrankungen |
WO1998010069A2 (en) * | 1996-09-06 | 1998-03-12 | The Regents Of The University Of California | E25a PROTEIN, METHODS FOR PRODUCTION AND USE THEREOF |
WO1999056763A1 (en) | 1998-05-07 | 1999-11-11 | The Regents Of The University Of California | Use of neglected target tissue antigens in modulation of immune responses |
AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
AU3774500A (en) | 1999-03-31 | 2000-10-16 | Curagen Corporation | Nucleic acids including open reading frames encoding polypeptides; "orfx" |
IL132611A0 (en) | 1999-10-27 | 2001-03-19 | Yeda Res & Dev | Synthetic genes and polypeptides and pharmaceutical compositions comprising them |
WO2001053531A2 (en) | 2000-01-18 | 2001-07-26 | Pharmacia Corporation | Osteoarthritis tissue derived nucleic acids, polypeptides, vectors, and cells |
US6962988B2 (en) | 2000-01-20 | 2005-11-08 | University Of Virginia Patent Foundation | Egg specific surface proteins |
WO2001055321A2 (en) | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
GB2373500B (en) | 2000-02-04 | 2004-12-15 | Aeomica Inc | Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence |
US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
WO2001088188A2 (en) | 2000-05-18 | 2001-11-22 | Nihon University, School Juridical Person | Method for examining ischemic conditions |
US20030165843A1 (en) | 2000-07-28 | 2003-09-04 | Avi Shoshan | Oligonucleotide library for detecting RNA transcripts and splice variants that populate a transcriptome |
US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
WO2003010327A2 (en) | 2001-02-21 | 2003-02-06 | Curagen Corporation | Novel proteins and nucleic acids encoding same |
DK1573022T3 (da) | 2001-04-10 | 2011-09-12 | Agensys Inc | Nukleinsyre og tilsvarende protein betegnet 184P1E2, der er egnede til behandling og påvisning af cancer |
CN100523196C (zh) | 2001-05-03 | 2009-08-05 | 欧加农股份有限公司 | 肽基精氨酸脱亚氨酶6 |
-
2002
- 2002-04-09 DK DK02731360.0T patent/DK1573022T3/da active
- 2002-04-09 US US10/120,907 patent/US20040062761A1/en not_active Abandoned
- 2002-04-09 US US10/120,901 patent/US7135549B1/en not_active Expired - Fee Related
- 2002-04-09 AU AU2002303340A patent/AU2002303340A1/en not_active Abandoned
- 2002-04-09 EP EP02731360A patent/EP1573022B1/en not_active Expired - Lifetime
- 2002-04-09 WO PCT/US2002/011643 patent/WO2002083919A2/en not_active Application Discontinuation
- 2002-04-09 PT PT02731360T patent/PT1573022E/pt unknown
- 2002-04-09 AT AT02731360T patent/ATE512216T1/de active
- 2002-04-09 WO PCT/US2002/011644 patent/WO2002083860A2/en not_active Application Discontinuation
- 2002-04-09 CA CA002443147A patent/CA2443147A1/en not_active Abandoned
-
2006
- 2006-03-02 US US11/368,284 patent/US7592149B2/en not_active Expired - Fee Related
-
2007
- 2007-08-03 US US11/833,918 patent/US7667015B2/en not_active Expired - Fee Related
-
2009
- 2009-01-21 US US12/357,154 patent/US7879570B2/en not_active Expired - Fee Related
-
2010
- 2010-01-14 US US12/687,768 patent/US7960527B2/en not_active Expired - Fee Related
-
2011
- 2011-01-05 US US12/985,245 patent/US8168187B2/en not_active Expired - Fee Related
- 2011-01-28 US US13/016,639 patent/US20110123539A1/en not_active Abandoned
- 2011-08-30 CY CY20111100824T patent/CY1113064T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1573022A4 (en) | 2008-01-09 |
EP1573022A2 (en) | 2005-09-14 |
US20090264381A1 (en) | 2009-10-22 |
US7879570B2 (en) | 2011-02-01 |
WO2002083860A2 (en) | 2002-10-24 |
US7135549B1 (en) | 2006-11-14 |
US20110110952A1 (en) | 2011-05-12 |
US20110123539A1 (en) | 2011-05-26 |
AU2002303340A8 (en) | 2007-08-30 |
DK1573022T3 (da) | 2011-09-12 |
WO2002083860A9 (en) | 2013-11-07 |
AU2002303340A1 (en) | 2002-10-28 |
US7960527B2 (en) | 2011-06-14 |
US20040062761A1 (en) | 2004-04-01 |
US20100168214A1 (en) | 2010-07-01 |
ATE512216T1 (de) | 2011-06-15 |
WO2002083919A3 (en) | 2007-06-28 |
PT1573022E (pt) | 2011-08-23 |
US7592149B2 (en) | 2009-09-22 |
US20070054284A1 (en) | 2007-03-08 |
WO2002083919A2 (en) | 2002-10-24 |
US20090148854A1 (en) | 2009-06-11 |
EP1573022B1 (en) | 2011-06-08 |
US7667015B2 (en) | 2010-02-23 |
CA2443147A1 (en) | 2002-10-24 |
US8168187B2 (en) | 2012-05-01 |
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