CA2335876A1 - Protease inhibitors - Google Patents
Protease inhibitors Download PDFInfo
- Publication number
- CA2335876A1 CA2335876A1 CA002335876A CA2335876A CA2335876A1 CA 2335876 A1 CA2335876 A1 CA 2335876A1 CA 002335876 A CA002335876 A CA 002335876A CA 2335876 A CA2335876 A CA 2335876A CA 2335876 A1 CA2335876 A1 CA 2335876A1
- Authority
- CA
- Canada
- Prior art keywords
- ylcarbonyl
- thiazol
- hydrazide
- methylpropyl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Furan Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9049398P | 1998-06-24 | 1998-06-24 | |
US60/090,493 | 1998-06-24 | ||
PCT/US1999/014561 WO1999066925A1 (en) | 1998-06-24 | 1999-06-24 | Protease inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2335876A1 true CA2335876A1 (en) | 1999-12-29 |
Family
ID=22223011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002335876A Abandoned CA2335876A1 (en) | 1998-06-24 | 1999-06-24 | Protease inhibitors |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1093367A4 (de) |
JP (1) | JP2002518444A (de) |
AR (1) | AR018915A1 (de) |
AU (1) | AU4723799A (de) |
CA (1) | CA2335876A1 (de) |
WO (1) | WO1999066925A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030144175A1 (en) | 1998-12-23 | 2003-07-31 | Smithkline Beecham Corporation | Protease inhibitors |
AU1588901A (en) | 1999-11-10 | 2001-06-06 | Smithkline Beecham Corporation | Protease inhibitors |
JP2003513924A (ja) | 1999-11-10 | 2003-04-15 | スミスクライン・ビーチャム・コーポレイション | プロテア−ゼ阻害剤 |
EP1232154A4 (de) | 1999-11-10 | 2004-06-23 | Smithkline Beecham Corp | Protease inhibitoren |
CZ20023168A3 (cs) | 2000-03-21 | 2003-02-12 | Smithkline Beecham Corporation | Inhibitory proteázy |
EP1465862A1 (de) | 2002-01-17 | 2004-10-13 | SmithKline Beecham Corporation | Cycloalkyl-ketoamiden derivate und ihre verwendung als cathepsin-k-inhibitoren |
US7176310B1 (en) | 2002-04-09 | 2007-02-13 | Ucb Sa | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents |
US7273866B2 (en) | 2002-12-20 | 2007-09-25 | Bristol-Myers Squibb Company | 2-aryl thiazole derivatives as KCNQ modulators |
US6933308B2 (en) | 2002-12-20 | 2005-08-23 | Bristol-Myers Squibb Company | Aminoalkyl thiazole derivatives as KCNQ modulators |
JP4851337B2 (ja) * | 2003-11-10 | 2012-01-11 | シンタ ファーマシューティカルズ コーポレーション | ヘテロアリールヒドラゾン化合物 |
KR20150090282A (ko) * | 2006-12-29 | 2015-08-05 | 아비에 도이치란트 게엠베하 운트 콤파니 카게 | 카복스아미드 화합물 및 칼페인 억제제로서의 이의 용도 |
TWI453019B (zh) * | 2007-12-28 | 2014-09-21 | Abbvie Deutschland | 甲醯胺化合物 |
CN102408387A (zh) * | 2010-09-26 | 2012-04-11 | 韩南银 | 一种具有抗肿瘤作用的金属络合物 |
JP6243908B2 (ja) * | 2012-08-23 | 2017-12-06 | アリオス バイオファーマ インク. | パラミクソウイルス感染症を治療するための化合物 |
CN103113300A (zh) * | 2013-03-06 | 2013-05-22 | 广西中医药大学 | 一种具有抗肿瘤活性的化合物的制备方法和用途 |
CN104487415B (zh) * | 2013-05-08 | 2016-11-09 | 杨永亮 | 一种马来酰胺化合物、其制备方法及其用途 |
CN103242321A (zh) * | 2013-05-21 | 2013-08-14 | 苏州科捷生物医药有限公司 | 苄基哌嗪类化合物及其抗肿瘤用途 |
JP6485817B2 (ja) | 2013-08-21 | 2019-03-20 | ヤンセン バイオファーマ インク. | 抗ウイルス化合物 |
CN103880702B (zh) * | 2014-03-14 | 2016-04-13 | 浙江工业大学 | O-肉桂酰-氟苯水杨酰胺类化合物及其在制备抗白血病药物中的应用 |
CN103880703B (zh) * | 2014-03-14 | 2016-04-13 | 浙江工业大学 | O-肉桂酰-氟苯水杨酰胺类化合物及其在制备抗人胎盘绒毛癌药物中的应用 |
CN103880701B (zh) * | 2014-03-14 | 2016-04-13 | 浙江工业大学 | O-肉桂酰-氟苯水杨酰胺类化合物及其在制备抗人宫颈鳞状癌药物中的应用 |
MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ132798A3 (cs) * | 1995-10-30 | 1999-02-17 | Smithkline Beecham Corporation | Inhibitory proteázy |
-
1999
- 1999-06-22 AR ARP990102984A patent/AR018915A1/es unknown
- 1999-06-24 AU AU47237/99A patent/AU4723799A/en not_active Abandoned
- 1999-06-24 CA CA002335876A patent/CA2335876A1/en not_active Abandoned
- 1999-06-24 EP EP99930779A patent/EP1093367A4/de not_active Withdrawn
- 1999-06-24 JP JP2000555611A patent/JP2002518444A/ja not_active Withdrawn
- 1999-06-24 WO PCT/US1999/014561 patent/WO1999066925A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1999066925A1 (en) | 1999-12-29 |
EP1093367A1 (de) | 2001-04-25 |
EP1093367A4 (de) | 2003-03-05 |
AU4723799A (en) | 2000-01-10 |
AR018915A1 (es) | 2001-12-12 |
JP2002518444A (ja) | 2002-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |