CA2323771A1 - Phthalazinone pde iii/iv inhibitors - Google Patents

Phthalazinone pde iii/iv inhibitors Download PDF

Info

Publication number
CA2323771A1
CA2323771A1 CA002323771A CA2323771A CA2323771A1 CA 2323771 A1 CA2323771 A1 CA 2323771A1 CA 002323771 A CA002323771 A CA 002323771A CA 2323771 A CA2323771 A CA 2323771A CA 2323771 A1 CA2323771 A1 CA 2323771A1
Authority
CA
Canada
Prior art keywords
compounds
formula
compound
hydrogen
carboxamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002323771A
Other languages
English (en)
French (fr)
Inventor
Geert Jan Sterk
Margaretha Van Der Mey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2323771A1 publication Critical patent/CA2323771A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002323771A 1998-03-14 1999-03-04 Phthalazinone pde iii/iv inhibitors Abandoned CA2323771A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98104643.6 1998-03-14
EP98104643 1998-03-14
PCT/EP1999/001413 WO1999047505A1 (en) 1998-03-14 1999-03-04 Phthalazinone pde iii/iv inhibitors

Publications (1)

Publication Number Publication Date
CA2323771A1 true CA2323771A1 (en) 1999-09-23

Family

ID=8231589

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002323771A Abandoned CA2323771A1 (en) 1998-03-14 1999-03-04 Phthalazinone pde iii/iv inhibitors

Country Status (12)

Country Link
US (1) US6255303B1 (enExample)
EP (1) EP1070056B1 (enExample)
JP (1) JP2002506856A (enExample)
AT (1) ATE270278T1 (enExample)
AU (1) AU3328499A (enExample)
CA (1) CA2323771A1 (enExample)
DE (1) DE69918422T2 (enExample)
DK (1) DK1070056T3 (enExample)
ES (1) ES2224628T3 (enExample)
PT (1) PT1070056E (enExample)
SI (1) SI1070056T1 (enExample)
WO (1) WO1999047505A1 (enExample)

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Also Published As

Publication number Publication date
AU3328499A (en) 1999-10-11
ATE270278T1 (de) 2004-07-15
ES2224628T3 (es) 2005-03-01
DK1070056T3 (da) 2004-11-08
US6255303B1 (en) 2001-07-03
JP2002506856A (ja) 2002-03-05
EP1070056A1 (en) 2001-01-24
EP1070056B1 (en) 2004-06-30
DE69918422T2 (de) 2005-08-11
WO1999047505A1 (en) 1999-09-23
PT1070056E (pt) 2004-11-30
DE69918422D1 (de) 2004-08-05
SI1070056T1 (en) 2004-12-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued