|
US6403597B1
(en)
|
1997-10-28 |
2002-06-11 |
Vivus, Inc. |
Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
|
|
US6548490B1
(en)
*
|
1997-10-28 |
2003-04-15 |
Vivus, Inc. |
Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
|
|
WO2001019818A1
(en)
*
|
1999-09-14 |
2001-03-22 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Phthalazinone derivatives as pd3/4 inhibitors
|
|
CA2388119A1
(en)
|
1999-10-25 |
2001-05-03 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Tetrahydrothiopy ranphthalazinone derivatives as pde4 inhibitors
|
|
US6756371B1
(en)
|
1999-10-25 |
2004-06-29 |
Altana Pharma Ag |
Phthalazinone derivatives as PDE4 inhibitors
|
|
CZ304043B6
(cs)
|
2000-08-05 |
2013-09-04 |
Glaxo Group Limited |
Estery steroidních thiokyselin
|
|
GB0103630D0
(en)
|
2001-02-14 |
2001-03-28 |
Glaxo Group Ltd |
Chemical compounds
|
|
HRP20030636B1
(en)
*
|
2001-02-15 |
2012-05-31 |
Nycomed Gmbh |
Phthalayinone-piperidino-derivatives as pde4 inhibitors
|
|
WO2002076933A1
(en)
|
2001-03-22 |
2002-10-03 |
Glaxo Group Limited |
Formailide derivatives as beta2-adrenoreceptor agonists
|
|
EA200301100A1
(ru)
*
|
2001-04-25 |
2004-06-24 |
Алтана Фарма Аг |
Новые фталазиноны
|
|
PL363544A1
(en)
*
|
2001-04-25 |
2004-11-29 |
Altana Pharma Ag |
Piperazino-derivatives and their use as pde4 inhibitor
|
|
US7291608B2
(en)
|
2001-04-30 |
2007-11-06 |
Glaxo Group Limited |
Anti-inflammatory 17.β.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.α
|
|
WO2003008396A1
(en)
*
|
2001-07-16 |
2003-01-30 |
Nikken Chemicals Co., Ltd. |
Optically active oxazine derivative
|
|
US6479493B1
(en)
|
2001-08-23 |
2002-11-12 |
Cell Pathways, Inc. |
Methods for treatment of type I diabetes
|
|
US20030073711A1
(en)
*
|
2001-08-23 |
2003-04-17 |
Whitehead Clark M. |
Methods for treatment of scleroderma
|
|
BRPI0212455B8
(pt)
|
2001-09-14 |
2021-05-25 |
Glaxo Group Ltd |
composto derivado de fenetanolamina para o tratamento de doenças respiratórias, formulação farmacêutica, combinação, e, uso do mesmo
|
|
GB0201677D0
(en)
|
2002-01-25 |
2002-03-13 |
Glaxo Group Ltd |
Medicament dispenser
|
|
EP1497261B1
(en)
|
2002-04-25 |
2007-12-19 |
Glaxo Group Limited |
Phenethanolamine derivatives
|
|
GB0217225D0
(en)
|
2002-07-25 |
2002-09-04 |
Glaxo Group Ltd |
Medicinal compounds
|
|
AU2003255376A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-derivatives as pde4 inhibitors
|
|
WO2004018457A1
(en)
*
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Pyrrolidinedione substituted piperidine-phthalazones as pde4 inhibitors
|
|
JP2005538138A
(ja)
*
|
2002-08-10 |
2005-12-15 |
アルタナ ファルマ アクチエンゲゼルシャフト |
Pde4インヒビターとしてのピリダジノン誘導体
|
|
AU2003260371A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
|
NZ539676A
(en)
|
2002-10-28 |
2006-10-27 |
Glaxo Group Ltd |
Phenethanolamine derivative for the treatment of respiratory diseases
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
GB0303396D0
(en)
|
2003-02-14 |
2003-03-19 |
Glaxo Group Ltd |
Medicinal compounds
|
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0317374D0
(en)
|
2003-07-24 |
2003-08-27 |
Glaxo Group Ltd |
Medicament dispenser
|
|
GB0329182D0
(en)
|
2003-12-17 |
2004-01-21 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP1716133B1
(en)
|
2004-02-04 |
2008-03-26 |
Nycomed GmbH |
2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
|
|
WO2005075437A1
(en)
*
|
2004-02-04 |
2005-08-18 |
Altana Pharma Ag |
Pyridazinone derivatives and their use as pde4 inhibitors
|
|
TWI341836B
(en)
|
2004-03-11 |
2011-05-11 |
Theravance Inc |
Biphenyl compounds useful as muscarinic receptor antagonists
|
|
PE20060272A1
(es)
|
2004-05-24 |
2006-05-22 |
Glaxo Group Ltd |
(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
GB0418045D0
(en)
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
|
US7569586B2
(en)
|
2004-08-16 |
2009-08-04 |
Theravance, Inc. |
Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
|
|
ATE517908T1
(de)
|
2005-01-10 |
2011-08-15 |
Glaxo Group Ltd |
Androstan-17-alpha-carbonat-derivate zur verwendung bei der behandlung allergischer und entzündlicher zustände
|
|
PE20061351A1
(es)
|
2005-03-25 |
2007-01-14 |
Glaxo Group Ltd |
COMPUESTOS 8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA 2,4,8-TRISUSTITUIDOS COMO INHIBIDORES DE LA QUINASA CSBP/RK/p38
|
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
|
PE20071068A1
(es)
|
2005-12-20 |
2007-12-13 |
Glaxo Group Ltd |
Acido 3-(4-{[4-(4-{[3-(3,3-dimetil-1-piperidinil)propil]oxi}fenil)-1-piperidinil]carbonil}-1-naftalenil)propanoico o propenoico, sales de los mismos, como antagonistas de los receptores h1 y h3
|
|
TW200811111A
(en)
|
2006-04-20 |
2008-03-01 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
|
JP5335675B2
(ja)
|
2006-07-25 |
2013-11-06 |
セファロン、インク. |
ピリジジノン誘導体
|
|
WO2008111631A1
(ja)
*
|
2007-03-14 |
2008-09-18 |
Nippon Shinyaku Co., Ltd. |
α-メチルベンジルアミン塩の製法
|
|
AR065804A1
(es)
|
2007-03-23 |
2009-07-01 |
Smithkline Beecham Corp |
Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
|
|
US7943658B2
(en)
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
|
SG190667A1
(en)
|
2008-05-23 |
2013-06-28 |
Panmira Pharmaceuticals Llc |
5-lipoxygenase-activating protein inhibitor
|
|
ES2566339T3
(es)
|
2008-06-05 |
2016-04-12 |
Glaxo Group Limited |
Derivados de 4-carboxamida indazol útiles como inhibidores de PI3-quinasas
|
|
CN103709148B
(zh)
*
|
2008-06-24 |
2015-10-21 |
霍夫曼-拉罗奇有限公司 |
取代的吡啶-2-酮和哒嗪-3-酮
|
|
JP5490789B2
(ja)
*
|
2008-07-02 |
2014-05-14 |
エフ.ホフマン−ラ ロシュ アーゲー |
キナーゼ阻害剤としての新規なフェニルピラジノン
|
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
|
US8524751B2
(en)
|
2009-03-09 |
2013-09-03 |
GlaxoSmithKline Intellecutual Property Development |
4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
|
|
EP2406249A1
(en)
|
2009-03-10 |
2012-01-18 |
Glaxo Group Limited |
Indole derivatives as ikk2 inhibitors
|
|
EP2408769A1
(en)
|
2009-03-17 |
2012-01-25 |
Glaxo Group Limited |
Pyrimidine derivatives used as itk inhibitors
|
|
KR20110137799A
(ko)
|
2009-03-19 |
2011-12-23 |
머크 샤프 앤드 돔 코포레이션 |
짧은 간섭 핵산 (siNA) 서열 목록을 사용한 BTB 및 CNC 상동체 1, 염기성 류신 지퍼 전사 인자 1 (BACH1) 유전자 발현의 RNA 간섭 매개 억제
|
|
EP2408915A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
EP2408916A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
US20120035247A1
(en)
|
2009-03-19 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 6 (STAT6) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
JP2012521764A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いた胸腺間質性リンパ球新生因子(TSLP)遺伝子発現のRNA干渉媒介性阻害
|
|
WO2010111468A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
|
|
US20120010272A1
(en)
|
2009-03-27 |
2012-01-12 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of Apoptosis Signal-Regulating Kinase 1 (ASK1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
AU2010229847A1
(en)
|
2009-03-27 |
2011-10-13 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of the intercellular adhesion molecule 1 (ICAM-1)gene expression using short interfering nucleic acid (siNA)
|
|
EP2411019A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
TW201103892A
(en)
|
2009-04-24 |
2011-02-01 |
Glaxo Group Ltd |
Compounds
|
|
WO2010122088A1
(en)
|
2009-04-24 |
2010-10-28 |
Glaxo Group Limited |
Pyrazole and triazole carboxamides as crac channel inhibitors
|
|
ES2644724T3
(es)
|
2009-04-30 |
2017-11-30 |
Glaxo Group Limited |
Indazoles sustituidos con oxazol como inhibidores de PI3-cinasas
|
|
HUE026414T2
(hu)
|
2009-07-15 |
2016-05-30 |
Theravance Biopharma R&D Ip Llc |
Bifenil-vegyület kristályos szabad-bázis formája
|
|
EP2507226A1
(en)
|
2009-12-03 |
2012-10-10 |
Glaxo Group Limited |
Novel compounds
|
|
US20120238571A1
(en)
|
2009-12-03 |
2012-09-20 |
Glaxo Group Limited |
Indazole derivatives as pi 3-kinase
|
|
JP2013512879A
(ja)
|
2009-12-03 |
2013-04-18 |
グラクソ グループ リミテッド |
Pi3キナーゼの阻害剤としてのベンズピラゾール誘導体
|
|
EP2512438B1
(en)
|
2009-12-16 |
2017-01-25 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
|
HUE026059T2
(en)
|
2010-09-08 |
2016-05-30 |
Glaxosmithkline Ip Dev Ltd |
N- [5- [4- (5 - {[(2R, 6S) -2,6-dimethyl-4-morpholinyl] methyl} -1,3-oxazol-2-yl) -1H-indazol-6-yl ] Polymorphs and salts of 2 - (methyloxy) -3-pyridinyl] methanesulfonamide
|
|
JP5876051B2
(ja)
|
2010-09-08 |
2016-03-02 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
インフルエンザウィルス感染の治療に使用するためのインダゾール誘導体
|
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
|
EP2630127A1
(en)
|
2010-10-21 |
2013-08-28 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
|
JP5795643B2
(ja)
|
2010-10-21 |
2015-10-14 |
グラクソ グループ リミテッドGlaxo Group Limited |
アレルギー性状態、免疫性状態及び炎症性状態に作用するピラゾール化合物
|
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
|
WO2012123312A1
(en)
|
2011-03-11 |
2012-09-20 |
Glaxo Group Limited |
Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
|
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
|
US20140112945A1
(en)
*
|
2011-06-17 |
2014-04-24 |
Takeda Gmbh |
Novel phthalazinone-pyrrolopyrimidinecarboxamide derivatives
|
|
WO2013106547A1
(en)
|
2012-01-10 |
2013-07-18 |
President And Fellows Of Harvard College |
Beta-cell replication promoting compounds and methods of their use
|
|
EP2968323A4
(en)
|
2013-03-13 |
2016-12-14 |
Flatley Discovery Lab |
PYRIDAZINONE COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS
|
|
US20140275102A1
(en)
*
|
2013-03-14 |
2014-09-18 |
Cephalon, Inc. |
Solid State Forms of 6-[4-[3-((R)-2-Methylpyrrolidine-1-yl)-propoxy]phenyl] 2H-pyridazine-3-one Hydrochloride
|
|
US20160263109A1
(en)
|
2013-10-17 |
2016-09-15 |
Glaxosmithkline Intellectual Property Development Limited |
P13k inhibitor for treatment of respiratory disease
|
|
AU2014336250A1
(en)
|
2013-10-17 |
2016-04-14 |
Glaxosmithkline Intellectual Property Development Limited |
PI3K inhibitor for treatment of respiratory disease
|
|
JP2017515840A
(ja)
|
2014-05-12 |
2017-06-15 |
グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited |
感染症を治療するためのダニリキシンを含む医薬組成物
|
|
JP6506836B2
(ja)
|
2014-08-14 |
2019-04-24 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の処置および予防のための新規ピリダゾンおよびトリアジノン
|
|
CN104478809B
(zh)
*
|
2014-11-14 |
2016-08-17 |
成都新恒创药业有限公司 |
一种左西孟旦杂质及其制备和检测方法
|
|
GB201602527D0
(en)
|
2016-02-12 |
2016-03-30 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
EP3497100A1
(en)
|
2016-08-08 |
2019-06-19 |
GlaxoSmithKline Intellectual Property Development Limited |
Chemical compounds
|
|
WO2018094392A1
(en)
|
2016-11-21 |
2018-05-24 |
Lupin Inc. |
Medicament dispenser
|
|
GB201706102D0
(en)
|
2017-04-18 |
2017-05-31 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
GB201712081D0
(en)
|
2017-07-27 |
2017-09-13 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
WO2019195711A1
(en)
|
2018-04-06 |
2019-10-10 |
Lupin Inc. |
Medicament dispenser
|
|
WO2020058823A1
(en)
|
2018-09-17 |
2020-03-26 |
Lupin, Inc. |
Dose indicator assembly for a medicament dispenser
|
|
IL296794A
(en)
|
2020-03-25 |
2022-11-01 |
Lupin Inc |
Multi-carrier medicament dispensers
|
|
IL300058A
(en)
|
2020-07-23 |
2023-03-01 |
Lupin Inc |
Dose counter assemblies for pharmaceutical devices
|