CA2308599C - Dna polymorphism identity determination using flow cytometry - Google Patents
Dna polymorphism identity determination using flow cytometry Download PDFInfo
- Publication number
- CA2308599C CA2308599C CA2308599A CA2308599A CA2308599C CA 2308599 C CA2308599 C CA 2308599C CA 2308599 A CA2308599 A CA 2308599A CA 2308599 A CA2308599 A CA 2308599A CA 2308599 C CA2308599 C CA 2308599C
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- CA
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- Prior art keywords
- oligonucleotide
- microsphere
- dna
- base
- dna strand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6862—Ligase chain reaction [LCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6368597P | 1997-10-28 | 1997-10-28 | |
| US60/063,685 | 1997-10-28 | ||
| PCT/US1998/023143 WO1999022030A1 (en) | 1997-10-28 | 1998-10-28 | Dna polymorphism identity determination using flow cytometry |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2308599A1 CA2308599A1 (en) | 1999-05-06 |
| CA2308599C true CA2308599C (en) | 2012-05-22 |
Family
ID=22050818
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2308599A Expired - Fee Related CA2308599C (en) | 1997-10-28 | 1998-10-28 | Dna polymorphism identity determination using flow cytometry |
| CA002306907A Abandoned CA2306907A1 (en) | 1997-10-28 | 1998-10-28 | Dna base mismatch detection using flow cytometry |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002306907A Abandoned CA2306907A1 (en) | 1997-10-28 | 1998-10-28 | Dna base mismatch detection using flow cytometry |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6287766B1 (https=) |
| EP (3) | EP2034031A1 (https=) |
| JP (3) | JP4502502B2 (https=) |
| AT (1) | ATE419382T1 (https=) |
| AU (2) | AU1207799A (https=) |
| CA (2) | CA2308599C (https=) |
| DE (1) | DE69840416D1 (https=) |
| DK (1) | DK1040202T3 (https=) |
| ES (1) | ES2320604T3 (https=) |
| IL (2) | IL135852A0 (https=) |
| IS (2) | IS2699B (https=) |
| PT (1) | PT1040202E (https=) |
| WO (2) | WO1999022030A1 (https=) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999022030A1 (en) * | 1997-10-28 | 1999-05-06 | The Regents Of The University Of California | Dna polymorphism identity determination using flow cytometry |
| JP4318859B2 (ja) * | 1997-12-04 | 2009-08-26 | ジーイー・ヘルスケア・ユーケイ・リミテッド | 複合アッセイ方法 |
| AU3519900A (en) * | 1999-03-19 | 2000-10-09 | Aclara Biosciences, Inc. | Methods for single nucleotide polymorphism detection |
| JP3668075B2 (ja) | 1999-10-12 | 2005-07-06 | 光夫 板倉 | 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたＳＮＰｓ高速スコアリング方法 |
| DE19958980A1 (de) * | 1999-11-18 | 2001-09-27 | Wolfgang Goehde | Verfahren zur Bestimmung von PCR-Produkten, sowie ein PCR-Detektions-Kit und eine Vorrichtung für ein solches Verfahren |
| EP1990428B1 (en) * | 2000-02-07 | 2010-12-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| US6340566B1 (en) * | 2000-03-28 | 2002-01-22 | The Regents Of The University Of California | Detection and quantitation of single nucleotide polymorphisms, DNA sequence variations, DNA mutations, DNA damage and DNA mismatches |
| US6365355B1 (en) | 2000-03-28 | 2002-04-02 | The Regents Of The University Of California | Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches |
| ATE497018T1 (de) | 2000-05-19 | 2011-02-15 | Eragen Biosciences Inc | Materialien und methoden zum nachweis von nukleinsäuren |
| US6977161B2 (en) | 2000-10-14 | 2005-12-20 | Eragen Biosciences, Inc. | Solid support assay systems and methods utilizing non-standard bases |
| KR20020065471A (ko) * | 2000-08-30 | 2002-08-13 | 산코 준야쿠 가부시키가이샤 | 유전자의 검출방법 |
| US7465540B2 (en) * | 2000-09-21 | 2008-12-16 | Luminex Corporation | Multiple reporter read-out for bioassays |
| US6592713B2 (en) | 2000-12-18 | 2003-07-15 | Sca Hygiene Products Ab | Method of producing a nonwoven material |
| US7083951B2 (en) * | 2001-02-14 | 2006-08-01 | The Regents Of The University Of California | Flow cytometric detection method for DNA samples |
| US20020115116A1 (en) * | 2001-02-22 | 2002-08-22 | Yong Song | Multiplex protein interaction determinations using glutathione-GST binding |
| US7153656B2 (en) * | 2001-09-11 | 2006-12-26 | Los Alamos National Security, Llc | Nucleic acid sequence detection using multiplexed oligonucleotide PCR |
| EP1463825B1 (en) | 2001-10-15 | 2017-12-06 | BioArray Solutions Ltd. | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
| US7179598B2 (en) * | 2001-11-20 | 2007-02-20 | The Regents Of The University Of California | Early leukemia diagnostics using microsphere arrays |
| WO2003054232A2 (en) * | 2001-12-13 | 2003-07-03 | Blue Heron Biotechnology, Inc. | Methods for removal of double-stranded oligonucleotides containing sequence errors using mismatch recognition proteins |
| US7282355B2 (en) | 2002-03-13 | 2007-10-16 | Syngenta Participations Ag | Nucleic acid detection method |
| US7304128B2 (en) * | 2002-06-04 | 2007-12-04 | E.I. Du Pont De Nemours And Company | Carbon nanotube binding peptides |
| US20040096870A1 (en) * | 2002-06-28 | 2004-05-20 | Sention, Inc. | Methods of detecting sequence differences |
| EP1613768A4 (en) * | 2003-03-11 | 2006-05-31 | Gene Check Inc | RECA-SUPPORTED ALLELSPECIFIC OLIGONUCLEOTIDE EXTENSION PROCESS |
| EP1606419A1 (en) | 2003-03-18 | 2005-12-21 | Quantum Genetics Ireland Limited | Systems and methods for improving protein and milk production of dairy herds |
| WO2004090153A2 (en) * | 2003-04-01 | 2004-10-21 | Eragen Biosciences,Inc. | Polymerase inhibitor and method of using same |
| US20060134638A1 (en) * | 2003-04-02 | 2006-06-22 | Blue Heron Biotechnology, Inc. | Error reduction in automated gene synthesis |
| EP1725572B1 (de) | 2003-11-05 | 2017-05-31 | AGCT GmbH | Makromolekulare nukleotidverbindungen und methoden zu deren anwendung |
| MXPA06009452A (es) | 2004-02-19 | 2007-03-15 | Univ Alberta | Polimorfismos del promotor de leptin y sus usos. |
| DE102005008583B4 (de) * | 2005-02-24 | 2007-10-25 | Johannes-Gutenberg-Universität Mainz | Verfahren zur Typisierung eines Individuums mittels short tandem repeat (STR)-Loci der genomischen DNA |
| JP4399575B2 (ja) * | 2005-03-31 | 2010-01-20 | 独立行政法人産業技術総合研究所 | 遺伝子断片中のヌクレオチドの種類の特定方法 |
| US8293472B2 (en) * | 2005-06-07 | 2012-10-23 | Luminex Corporation | Methods for detection and typing of nucleic acids |
| EP1953241A1 (en) * | 2005-11-29 | 2008-08-06 | Olympus Corporation | Method of analyzing change in primary structure of nucleic acid |
| US8871687B2 (en) * | 2007-09-28 | 2014-10-28 | Quest Diagnostics Investments Incorporated | Nucleic acid sequencing by single-base primer extension |
| US7960116B2 (en) * | 2007-09-28 | 2011-06-14 | Pacific Biosciences Of California, Inc. | Nucleic acid sequencing methods and systems |
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- 1998-10-28 EP EP08104631A patent/EP2034031A1/en not_active Withdrawn
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- 1998-10-28 IL IL13585298A patent/IL135852A0/xx unknown
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- 1998-10-28 EP EP98955221A patent/EP1032701A1/en not_active Withdrawn
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| IS2699B (is) | 2010-11-15 |
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| IS5454A (is) | 2000-04-14 |
| CA2306907A1 (en) | 1999-05-06 |
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| EP1032701A1 (en) | 2000-09-06 |
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| ATE419382T1 (de) | 2009-01-15 |
| IL135851A0 (en) | 2001-05-20 |
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| EP1040202B9 (en) | 2009-09-23 |
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| ES2320604T3 (es) | 2009-05-25 |
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| CA2308599A1 (en) | 1999-05-06 |
| IL135852A0 (en) | 2001-05-20 |
| AU754849B2 (en) | 2002-11-28 |
| WO1999022029A1 (en) | 1999-05-06 |
| JP2003502005A (ja) | 2003-01-21 |
| JP4502502B2 (ja) | 2010-07-14 |
| DK1040202T3 (da) | 2009-04-14 |
| DE69840416D1 (de) | 2009-02-12 |
| EP1040202A4 (en) | 2004-08-18 |
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