CA2220963A1 - Process for preparing 4-aryl-piperidine derivatives - Google Patents
Process for preparing 4-aryl-piperidine derivatives Download PDFInfo
- Publication number
- CA2220963A1 CA2220963A1 CA002220963A CA2220963A CA2220963A1 CA 2220963 A1 CA2220963 A1 CA 2220963A1 CA 002220963 A CA002220963 A CA 002220963A CA 2220963 A CA2220963 A CA 2220963A CA 2220963 A1 CA2220963 A1 CA 2220963A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- formula
- treatment
- defined above
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK56395 | 1995-05-17 | ||
DK0563/95 | 1995-05-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2220963A1 true CA2220963A1 (en) | 1996-11-21 |
Family
ID=8094959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002220963A Abandoned CA2220963A1 (en) | 1995-05-17 | 1996-04-25 | Process for preparing 4-aryl-piperidine derivatives |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0828735A1 (ja) |
JP (1) | JPH11505229A (ja) |
CN (1) | CN1068597C (ja) |
AU (1) | AU721257B2 (ja) |
BR (1) | BR9608471A (ja) |
CA (1) | CA2220963A1 (ja) |
HU (1) | HUP9900318A3 (ja) |
IL (1) | IL118294A0 (ja) |
NZ (1) | NZ307479A (ja) |
WO (1) | WO1996036636A1 (ja) |
ZA (1) | ZA963951B (ja) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9526645D0 (en) * | 1995-12-28 | 1996-02-28 | Chiroscience Ltd | Stereoselective synthesis |
ES2117557B1 (es) * | 1996-02-29 | 1999-07-01 | Ferrer Int | Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina. |
EP1384711A1 (en) | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Optical resolution of a piperidine derivative |
HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
GB9623359D0 (en) * | 1996-11-09 | 1997-01-08 | Smithkline Beecham Plc | Novel process |
GB9700690D0 (en) | 1997-01-15 | 1997-03-05 | Smithkline Beecham Plc | Novel process |
GB9710004D0 (en) * | 1997-05-17 | 1997-07-09 | Knoll Ag | Chemical process |
AP9901698A0 (en) | 1997-05-29 | 1999-12-31 | Smithkline Beecham Corp | Novel process. |
SI0994872T1 (ja) * | 1997-06-10 | 2001-08-31 | Synthon Bv | |
CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
GB9826175D0 (en) * | 1998-11-28 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
GB9828767D0 (en) * | 1998-12-29 | 1999-02-17 | Smithkline Beecham Plc | Novel process |
IT1308629B1 (it) * | 1999-02-23 | 2002-01-09 | Recordati Chem Pharm | Processo per la produzione di paroxetina. |
IT1313702B1 (it) | 1999-08-02 | 2002-09-09 | Chemi Spa | Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine. |
AU1018801A (en) * | 1999-10-29 | 2001-05-14 | Novo Nordisk A/S | Use of 3,4-substituted piperidines |
GB9930577D0 (en) * | 1999-12-23 | 2000-02-16 | Smithkline Beecham Plc | Novel process |
WO2001085688A1 (en) | 2000-05-12 | 2001-11-15 | Synthon B.V. | TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS |
WO2002006275A1 (en) * | 2000-07-17 | 2002-01-24 | Smithkline Beecham P.L.C. | Novel processes for the preparation of 4-phenylpiperidine derivatives |
GB0021147D0 (en) * | 2000-08-30 | 2000-10-11 | Knoll Ag | Chemical process |
GB0021145D0 (en) * | 2000-08-30 | 2000-10-11 | Knoll Ag | Chemical process |
WO2002028834A1 (en) * | 2000-10-06 | 2002-04-11 | Smithkline Beecham P.L.C. | Process for the preparation of aryl-piperidine carbinols and intermediates thereof |
EP1347960B1 (en) * | 2001-01-04 | 2004-11-17 | Ferrer Internacional, S.A. | Process for preparing (+) trans-4-p-fluorophenyl-3-hydroxymethyl-1 |
WO2015071831A1 (en) * | 2013-11-18 | 2015-05-21 | Piramal Enterprises Limited | An improved process for minimising the formation of dehalogenated byproducts |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
US4593036A (en) * | 1984-02-07 | 1986-06-03 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-[(4-methoxyphenoxy)methyl]-1-methylpiperidine useful as 5-HT potentiator |
IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
-
1996
- 1996-04-25 WO PCT/DK1996/000185 patent/WO1996036636A1/en not_active Application Discontinuation
- 1996-04-25 AU AU56845/96A patent/AU721257B2/en not_active Ceased
- 1996-04-25 CA CA002220963A patent/CA2220963A1/en not_active Abandoned
- 1996-04-25 HU HU9900318A patent/HUP9900318A3/hu unknown
- 1996-04-25 BR BR9608471A patent/BR9608471A/pt not_active Application Discontinuation
- 1996-04-25 JP JP8534464A patent/JPH11505229A/ja active Pending
- 1996-04-25 CN CN96193942A patent/CN1068597C/zh not_active Expired - Fee Related
- 1996-04-25 NZ NZ307479A patent/NZ307479A/xx unknown
- 1996-04-25 EP EP96914861A patent/EP0828735A1/en not_active Ceased
- 1996-05-16 IL IL11829496A patent/IL118294A0/xx unknown
- 1996-05-17 ZA ZA963951A patent/ZA963951B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA963951B (en) | 1997-01-21 |
NZ307479A (en) | 1999-08-30 |
IL118294A0 (en) | 1996-09-12 |
HUP9900318A2 (hu) | 1999-09-28 |
HUP9900318A3 (en) | 2001-09-28 |
EP0828735A1 (en) | 1998-03-18 |
AU5684596A (en) | 1996-11-29 |
AU721257B2 (en) | 2000-06-29 |
CN1184476A (zh) | 1998-06-10 |
JPH11505229A (ja) | 1999-05-18 |
WO1996036636A1 (en) | 1996-11-21 |
CN1068597C (zh) | 2001-07-18 |
BR9608471A (pt) | 1998-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20040426 |