CA2202904C - Pharmaceutical composition for prophylaxis and treatment of type i allergic diseases - Google Patents

Pharmaceutical composition for prophylaxis and treatment of type i allergic diseases Download PDF

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Publication number
CA2202904C
CA2202904C CA002202904A CA2202904A CA2202904C CA 2202904 C CA2202904 C CA 2202904C CA 002202904 A CA002202904 A CA 002202904A CA 2202904 A CA2202904 A CA 2202904A CA 2202904 C CA2202904 C CA 2202904C
Authority
CA
Canada
Prior art keywords
group
branched
straight
cyano
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002202904A
Other languages
English (en)
French (fr)
Other versions
CA2202904A1 (en
Inventor
Yukio Amano
Yuko Mizushima
Kenji Ogata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst Pharmaceuticals and Chemicals KK
Original Assignee
Hoechst Pharmaceuticals and Chemicals KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Pharmaceuticals and Chemicals KK filed Critical Hoechst Pharmaceuticals and Chemicals KK
Publication of CA2202904A1 publication Critical patent/CA2202904A1/en
Application granted granted Critical
Publication of CA2202904C publication Critical patent/CA2202904C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA002202904A 1994-10-17 1995-10-04 Pharmaceutical composition for prophylaxis and treatment of type i allergic diseases Expired - Fee Related CA2202904C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6/250293 1994-10-17
JP25029394 1994-10-17
PCT/JP1995/002027 WO1996011682A1 (fr) 1994-10-17 1995-10-04 Composition preventive et remede pour les maladies allergiques de type i

Publications (2)

Publication Number Publication Date
CA2202904A1 CA2202904A1 (en) 1996-04-25
CA2202904C true CA2202904C (en) 2006-12-19

Family

ID=17205757

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002202904A Expired - Fee Related CA2202904C (en) 1994-10-17 1995-10-04 Pharmaceutical composition for prophylaxis and treatment of type i allergic diseases

Country Status (19)

Country Link
US (1) US5814649A (ko)
EP (1) EP0787491B1 (ko)
KR (1) KR100365064B1 (ko)
AT (1) ATE194912T1 (ko)
AU (1) AU695907B2 (ko)
CA (1) CA2202904C (ko)
DE (1) DE69518159T2 (ko)
DK (1) DK0787491T3 (ko)
ES (1) ES2148561T3 (ko)
FI (1) FI971584A (ko)
GR (1) GR3034413T3 (ko)
HU (1) HU222888B1 (ko)
IL (1) IL115617A (ko)
NO (1) NO315928B1 (ko)
NZ (1) NZ293691A (ko)
PT (1) PT787491E (ko)
TW (1) TW429146B (ko)
WO (1) WO1996011682A1 (ko)
ZA (1) ZA958708B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2150808T3 (es) * 1997-08-08 2000-12-01 Aventis Pharma Gmbh Forma cristalina de (4-trifluorometil)-anilida de acido 5-metilisoxazol-4-carboxilico.
BR9908105A (pt) 1998-02-19 2000-10-17 Kowa Co Composto de amida cìclica.
US6303652B1 (en) 1998-08-21 2001-10-16 Hughes Institute BTK inhibitors and methods for their identification and use
WO2002034251A1 (en) * 2000-10-20 2002-05-02 Parker Hughes Institute Treatment of asthma with lfm analogues
EP1244468A2 (en) * 2000-01-07 2002-10-02 University Of Cincinnati Selective activation of a th1 or th2 lymphocyte regulated immune response
US6849260B2 (en) 2000-08-18 2005-02-01 Amgen Inc. Methods and compositions for treating IgE-related disease using NNT-1 inhibitors
US6706703B2 (en) 2001-06-29 2004-03-16 Kowa Co., Ltd. Bis(5-aryl-2-pyridyl) derivatives
US6890940B2 (en) 2001-06-29 2005-05-10 Kowa Co., Ltd. Bis(2-aryl-5-pyridyl) derivatives
US8283515B2 (en) 2002-05-03 2012-10-09 Sca Hygiene Products Ab Absorbent article containing a skin conditioning agent
PE20121478A1 (es) 2009-09-18 2012-11-12 Sanofi Sa Formulaciones en comprimido de teriflunomida: "(4'-trifluorometilfenil) amida del acido (z)-2-ciano-3-hidroxibut-2-enoico con estabilidad mejorada

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2854439A1 (de) * 1978-12-16 1980-07-03 Hoechst Ag Ein isoxazolderivat, verfahren zu seiner herstellung, diese verbindung enthaltende mittel und verwendung
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
DD297328A5 (de) * 1989-08-18 1992-01-09 �������@���������k���Kk�� 5-methyl-isoxalol-4-carbonsaeureanilide und 2 hydroxyethyliden-cyanoessigsaeureanilide zur behandlung von augenerkrankungen
US5001124A (en) * 1990-02-02 1991-03-19 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
DE4127737A1 (de) * 1991-08-22 1993-02-25 Hoechst Ag Arzneimittel zur behandlung von abstossungsreaktionen bei organverpflanzungen
TW314467B (ko) * 1993-03-31 1997-09-01 Hoechst Ag

Also Published As

Publication number Publication date
DE69518159T2 (de) 2002-01-03
IL115617A0 (en) 1996-01-19
HUT77135A (hu) 1998-03-02
DK0787491T3 (da) 2000-10-16
IL115617A (en) 1999-11-30
EP0787491B1 (en) 2000-07-26
EP0787491A4 (en) 1998-09-30
FI971584A0 (fi) 1997-04-15
FI971584A (fi) 1997-04-15
AU3618695A (en) 1996-05-06
KR970706811A (ko) 1997-12-01
KR100365064B1 (ko) 2003-04-11
ES2148561T3 (es) 2000-10-16
GR3034413T3 (en) 2000-12-29
ATE194912T1 (de) 2000-08-15
DE69518159D1 (de) 2000-08-31
CA2202904A1 (en) 1996-04-25
ZA958708B (en) 1996-05-14
NO971743D0 (no) 1997-04-16
WO1996011682A1 (fr) 1996-04-25
HU222888B1 (hu) 2003-12-29
NZ293691A (en) 1999-07-29
EP0787491A1 (en) 1997-08-06
US5814649A (en) 1998-09-29
PT787491E (pt) 2000-11-30
NO971743L (no) 1997-04-16
NO315928B1 (no) 2003-11-17
TW429146B (en) 2001-04-11
AU695907B2 (en) 1998-08-27

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MKLA Lapsed