US5914396A
(en)
*
|
1990-01-11 |
1999-06-22 |
Isis Pharmaceuticals, Inc. |
2'-O-modified nucleosides and phosphoramidites
|
US7101993B1
(en)
|
1990-01-11 |
2006-09-05 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides containing 2′-O-modified purines
|
DE69123979T2
(de)
|
1990-10-12 |
1997-04-30 |
Max Planck Gesellschaft |
Abgeänderte ribozyme
|
US6041910A
(en)
*
|
1997-09-22 |
2000-03-28 |
Jervis B. Webb Company |
Baggage pusher device and system
|
US5646267A
(en)
*
|
1991-08-05 |
1997-07-08 |
Polish Academy Of Sciences |
Method of making oligonucleotides and oligonucleotide analogs using phospholanes and enantiomerically resolved phospholane analogues
|
US5359052A
(en)
*
|
1991-08-05 |
1994-10-25 |
Polish Academy Of Sciences |
Chalcophospholanes useful in the synthesis of oligonucleoside phosphorothioates, phosphorodithioates and related selenates
|
US7119184B2
(en)
*
|
1991-08-12 |
2006-10-10 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides having A-DNA form and B-DNA form conformational geometry
|
US6369209B1
(en)
*
|
1999-05-03 |
2002-04-09 |
Isis Pharmaceuticals, Inc. |
Oligonucleotides having A-DNA form and B-DNA form conformational geometry
|
US5652094A
(en)
|
1992-01-31 |
1997-07-29 |
University Of Montreal |
Nucleozymes
|
US6204027B1
(en)
*
|
1992-02-26 |
2001-03-20 |
University Of Massachusetts Worcester |
Ribozymes having 2′-O substituted nucleotides in the flanking sequences
|
US20040054156A1
(en)
*
|
1992-05-14 |
2004-03-18 |
Kenneth Draper |
Method and reagent for inhibiting hepatitis B viral replication
|
US20030125270A1
(en)
*
|
2000-12-18 |
2003-07-03 |
Lawrence Blatt |
Enzymatic nucleic acid treatment of diseases or conditions related to hepatitis C virus infection
|
US20040127446A1
(en)
*
|
1992-05-14 |
2004-07-01 |
Lawrence Blatt |
Oligonucleotide mediated inhibition of hepatitis B virus and hepatitis C virus replication
|
US20030206887A1
(en)
*
|
1992-05-14 |
2003-11-06 |
David Morrissey |
RNA interference mediated inhibition of hepatitis B virus (HBV) using short interfering nucleic acid (siNA)
|
US5646042A
(en)
*
|
1992-08-26 |
1997-07-08 |
Ribozyme Pharmaceuticals, Inc. |
C-myb targeted ribozymes
|
US5891684A
(en)
*
|
1992-10-15 |
1999-04-06 |
Ribozyme Pharmaceuticals, Inc. |
Base-modified enzymatic nucleic acid
|
US5616488A
(en)
*
|
1992-12-07 |
1997-04-01 |
Ribozyme Pharmaceuticals, Inc. |
IL-5 targeted ribozymes
|
US5612215A
(en)
*
|
1992-12-07 |
1997-03-18 |
Ribozyme Pharmaceuticals, Inc. |
Stromelysin targeted ribozymes
|
US5811300A
(en)
*
|
1992-12-07 |
1998-09-22 |
Ribozyme Pharmaceuticals, Inc. |
TNF-α ribozymes
|
US5837542A
(en)
*
|
1992-12-07 |
1998-11-17 |
Ribozyme Pharmaceuticals, Inc. |
Intercellular adhesion molecule-1 (ICAM-1) ribozymes
|
US5567604A
(en)
*
|
1993-04-23 |
1996-10-22 |
Aronex Pharmaceuticals, Inc. |
Anti-viral guanosine-rich oligonucleotides
|
US6323185B1
(en)
*
|
1993-04-23 |
2001-11-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-viral guanosine-rich oligonucleotides and method of treating HIV
|
US6288042B1
(en)
|
1993-04-23 |
2001-09-11 |
Aronex Pharmaceuticals, Inc. |
Anti-viral guanosine-rich tetrad forming oligonucleotides
|
FR2705099B1
(fr)
*
|
1993-05-12 |
1995-08-04 |
Centre Nat Rech Scient |
Oligonucléotides phosphorothioates triesters et procédé de préparation.
|
US5955591A
(en)
*
|
1993-05-12 |
1999-09-21 |
Imbach; Jean-Louis |
Phosphotriester oligonucleotides, amidites and method of preparation
|
US5817635A
(en)
*
|
1993-08-09 |
1998-10-06 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Modified ribozymes
|
PT748382E
(pt)
*
|
1993-09-02 |
2003-03-31 |
Ribozyme Pharm Inc |
Acidos nucleicos enzimaticos contendo nao-nucleotidos
|
CA2174339A1
(fr)
*
|
1993-10-27 |
1995-05-04 |
Lech W. Dudycz |
2'-amido et 2'-peptido oligonucleotides modifies
|
WO1995013378A1
(fr)
|
1993-11-08 |
1995-05-18 |
Ribozyme Pharmaceuticals, Inc. |
Acide nucleique enzymatique a modification de base
|
US5631359A
(en)
*
|
1994-10-11 |
1997-05-20 |
Ribozyme Pharmaceuticals, Inc. |
Hairpin ribozymes
|
US5639647A
(en)
|
1994-03-29 |
1997-06-17 |
Ribozyme Pharmaceuticals, Inc. |
2'-deoxy-2'alkylnucleotide containing nucleic acid
|
US5869248A
(en)
*
|
1994-03-07 |
1999-02-09 |
Yale University |
Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
|
US5627053A
(en)
*
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
US6639061B1
(en)
*
|
1999-07-07 |
2003-10-28 |
Isis Pharmaceuticals, Inc. |
C3′-methylene hydrogen phosphonate oligomers and related compounds
|
US6103890A
(en)
*
|
1994-05-18 |
2000-08-15 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic nucleic acids that cleave C-fos
|
US5998193A
(en)
*
|
1994-06-24 |
1999-12-07 |
Gene Shears Pty., Ltd. |
Ribozymes with optimized hybridizing arms, stems, and loops, tRNA embedded ribozymes and compositions thereof
|
US5599706A
(en)
*
|
1994-09-23 |
1997-02-04 |
Stinchcomb; Dan T. |
Ribozymes targeted to apo(a) mRNA
|
US5716824A
(en)
|
1995-04-20 |
1998-02-10 |
Ribozyme Pharmaceuticals, Inc. |
2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes)
|
US5672501A
(en)
*
|
1994-12-23 |
1997-09-30 |
Ribozyme Pharmaceuticals, Inc. |
Base-modified enzymatic nucleic acid
|
WO1996018736A2
(fr)
*
|
1994-12-13 |
1996-06-20 |
Ribozyme Pharmaceuticals, Inc. |
Procede et reactif servant a traiter les etats arthritiques, a introduitre une tolerance aux greffes et a inverser les reactions immunes
|
US5705388A
(en)
*
|
1994-12-23 |
1998-01-06 |
Ribozyme Pharmaceuticals, Inc. |
CETP Ribozymes
|
US5663064A
(en)
*
|
1995-01-13 |
1997-09-02 |
University Of Vermont |
Ribozymes with RNA protein binding site
|
US5683873A
(en)
*
|
1995-01-13 |
1997-11-04 |
Innovir Laboratories, Inc. |
EGS-mediated inactivation of target RNA
|
US6057153A
(en)
*
|
1995-01-13 |
2000-05-02 |
Yale University |
Stabilized external guide sequences
|
US5910408A
(en)
*
|
1995-06-07 |
1999-06-08 |
The General Hospital Corporation |
Catalytic DNA having ligase activity
|
US5877021A
(en)
*
|
1995-07-07 |
1999-03-02 |
Ribozyme Pharmaceuticals, Inc. |
B7-1 targeted ribozymes
|
AU725936B2
(en)
*
|
1995-07-19 |
2000-10-26 |
Aronex Pharmaceuticals, Inc. |
Anti-viral guanosine-rich oligonucleotides
|
US20040220128A1
(en)
*
|
1995-10-26 |
2004-11-04 |
Sirna Therapeutics, Inc. |
Nucleic acid based modulation of female reproductive diseases and conditions
|
US20040142895A1
(en)
*
|
1995-10-26 |
2004-07-22 |
Sirna Therapeutics, Inc. |
Nucleic acid-based modulation of gene expression in the vascular endothelial growth factor pathway
|
US6346398B1
(en)
|
1995-10-26 |
2002-02-12 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor
|
US20040102389A1
(en)
*
|
1995-10-26 |
2004-05-27 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid-mediated treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)
|
US7034009B2
(en)
*
|
1995-10-26 |
2006-04-25 |
Sirna Therapeutics, Inc. |
Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)
|
US5998203A
(en)
|
1996-04-16 |
1999-12-07 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic nucleic acids containing 5'-and/or 3'-cap structures
|
JP4293636B2
(ja)
|
1996-02-14 |
2009-07-08 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
糖修飾ギャップ付オリゴヌクレオチド
|
US6238917B1
(en)
*
|
1996-04-02 |
2001-05-29 |
Commonwealth Scientific Industrial Research Organizaion |
Asymmetric hammerhead ribozymes
|
US6610478B1
(en)
|
1996-08-16 |
2003-08-26 |
Yale University |
Phenotypic conversion of cells mediated by external guide sequences
|
US5807743A
(en)
*
|
1996-12-03 |
1998-09-15 |
Ribozyme Pharmaceuticals, Inc. |
Interleukin-2 receptor gamma-chain ribozymes
|
AU5794598A
(en)
*
|
1996-12-13 |
1998-07-03 |
Patricia Tekamp-Olson |
Method for expression of heterologous proteins in yeast
|
US6248878B1
(en)
|
1996-12-24 |
2001-06-19 |
Ribozyme Pharmaceuticals, Inc. |
Nucleoside analogs
|
US20030186909A1
(en)
*
|
1997-01-27 |
2003-10-02 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid treatment of diseases or conditions related to levels of epidermal growth factor receptors
|
US6057156A
(en)
*
|
1997-01-31 |
2000-05-02 |
Robozyme Pharmaceuticals, Inc. |
Enzymatic nucleic acid treatment of diseases or conditions related to levels of epidermal growth factor receptors
|
CA2279488A1
(fr)
*
|
1997-02-04 |
1998-08-06 |
Aronex Pharmaceuticals, Inc. |
Oligonucleotides antiviraux riches en guanosine formant des tetrades
|
US6159951A
(en)
*
|
1997-02-13 |
2000-12-12 |
Ribozyme Pharmaceuticals Inc. |
2'-O-amino-containing nucleoside analogs and polynucleotides
|
US6251666B1
(en)
|
1997-03-31 |
2001-06-26 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid catalysts comprising L-nucleotide analogs
|
US6548657B1
(en)
|
1997-06-09 |
2003-04-15 |
Ribozyme Pharmaceuticals, Inc. |
Method for screening nucleic acid catalysts
|
US6280936B1
(en)
|
1997-06-09 |
2001-08-28 |
Ribozyme Pharmaceuticals, Inc. |
Method for screening nucleic acid catalysts
|
US6300483B1
(en)
*
|
1997-06-19 |
2001-10-09 |
Ribozyme Pharmaceuticals, Inc. |
Compositions inducing cleavage of RNA motifs
|
US6183959B1
(en)
|
1997-07-03 |
2001-02-06 |
Ribozyme Pharmaceuticals, Inc. |
Method for target site selection and discovery
|
US6316612B1
(en)
|
1997-08-22 |
2001-11-13 |
Ribozyme Pharmaceuticals, Inc. |
Xylofuranosly-containing nucleoside phosphoramidites and polynucleotides
|
JP2001518292A
(ja)
*
|
1997-09-22 |
2001-10-16 |
マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ |
エンドヌクレアーゼ活性を有する核酸触媒
|
US6656731B1
(en)
|
1997-09-22 |
2003-12-02 |
Max Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Nucleic acid catalysts with endonuclease activity
|
US6054576A
(en)
*
|
1997-10-02 |
2000-04-25 |
Ribozyme Pharmaceuticals, Inc. |
Deprotection of RNA
|
US6482932B1
(en)
|
1997-11-05 |
2002-11-19 |
Ribozyme Pharmaceuticals, Incorporated |
Nucleoside triphosphates and their incorporation into oligonucleotides
|
US6617438B1
(en)
|
1997-11-05 |
2003-09-09 |
Sirna Therapeutics, Inc. |
Oligoribonucleotides with enzymatic activity
|
US6013447A
(en)
*
|
1997-11-21 |
2000-01-11 |
Innovir Laboratories, Inc. |
Random intracellular method for obtaining optimally active nucleic acid molecules
|
US20020147143A1
(en)
|
1998-03-18 |
2002-10-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of lung cancer
|
US6248525B1
(en)
|
1998-03-30 |
2001-06-19 |
Yale University |
Method for identifying essential or functional genes
|
WO1999054459A2
(fr)
|
1998-04-20 |
1999-10-28 |
Ribozyme Pharmaceuticals, Inc. |
Molecules d'acides nucleiques presentant de nouvelles compositions chimiques capables de moduler l'expression genique
|
US6995259B1
(en)
*
|
1998-10-23 |
2006-02-07 |
Sirna Therapeutics, Inc. |
Method for the chemical synthesis of oligonucleotides
|
CA2368194A1
(fr)
*
|
1999-04-30 |
2000-11-09 |
University Of Florida |
Ribozymes fournis par virus adeno-associes pour la decouverte de fonctions geniques
|
AR025996A1
(es)
|
1999-10-07 |
2002-12-26 |
Valigen Us Inc |
Plantas no transgenicas resistentes a los herbicidas.
|
US6831171B2
(en)
*
|
2000-02-08 |
2004-12-14 |
Yale University |
Nucleic acid catalysts with endonuclease activity
|
US20050233329A1
(en)
*
|
2002-02-20 |
2005-10-20 |
Sirna Therapeutics, Inc. |
Inhibition of gene expression using duplex forming oligonucleotides
|
US8273866B2
(en)
*
|
2002-02-20 |
2012-09-25 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
|
CA2398282A1
(fr)
*
|
2000-02-11 |
2001-08-16 |
Ribozyme Pharmaceuticals, Inc. |
Methode et reactif destines a la modulation et au diagnostic de l'expression genetique de cd20 et de nogo
|
US20080039414A1
(en)
*
|
2002-02-20 |
2008-02-14 |
Sima Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US8202979B2
(en)
*
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
US7491805B2
(en)
*
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
WO2005041859A2
(fr)
|
2003-04-30 |
2005-05-12 |
Sirna Therapeutics, Inc. |
Conjugues et compositions
|
US7833992B2
(en)
*
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
US20050032733A1
(en)
*
|
2001-05-18 |
2005-02-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
US20050239061A1
(en)
*
|
2000-03-01 |
2005-10-27 |
Marshall William S |
Identification and use of effectors and allosteric molecules for the alteration of gene expression
|
US20040023292A1
(en)
*
|
2001-10-19 |
2004-02-05 |
Mcswiggen James |
Method and reagent for the detection of proteins and peptides
|
US20040009510A1
(en)
*
|
2000-03-06 |
2004-01-15 |
Scott Seiwert |
Allosteric nucleic acid sensor molecules
|
US20030065155A1
(en)
*
|
2000-03-06 |
2003-04-03 |
Nassim Usman |
Nucleic acid sensor molecules
|
US20020102694A1
(en)
*
|
2000-03-31 |
2002-08-01 |
Ronald Breaker |
Nucleozymes with endonuclease activity
|
DE60134158D1
(de)
|
2000-06-28 |
2008-07-03 |
Corixa Corp |
Zusammensetzungen und verfahren für therapie und diagnose von lungenkrebs
|
WO2002002792A1
(fr)
|
2000-06-30 |
2002-01-10 |
Molecular Staging, Inc. |
Amplification de signal par sondes lollipop
|
US8568766B2
(en)
|
2000-08-24 |
2013-10-29 |
Gattadahalli M. Anantharamaiah |
Peptides and peptide mimetics to treat pathologies associated with eye disease
|
US20050209179A1
(en)
*
|
2000-08-30 |
2005-09-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
|
US20080032942A1
(en)
*
|
2000-08-30 |
2008-02-07 |
Mcswiggen James |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA)
|
US20030190635A1
(en)
*
|
2002-02-20 |
2003-10-09 |
Mcswiggen James A. |
RNA interference mediated treatment of Alzheimer's disease using short interfering RNA
|
AU9684601A
(en)
|
2000-10-12 |
2002-04-22 |
Univ Rochester |
Compositions that inhibit proliferation of cancer cells
|
WO2002061133A2
(fr)
*
|
2000-11-09 |
2002-08-08 |
Yale University |
Detection d'acide nucleique avec des sondes structurees
|
EP1383782A1
(fr)
*
|
2001-03-26 |
2004-01-28 |
Sirna Therpeutics, Inc. |
Inhibition regulee par des oligonucleotides de la replication du virus de l'hepatite b et du virus de l'hepatite c
|
EP1386004A4
(fr)
*
|
2001-04-05 |
2005-02-16 |
Ribozyme Pharm Inc |
Modulation de l'expression genique associee a la proliferation inflammatoire et a la croissance de neurites, par des procedes faisant intervenir l'acide nucleique
|
JP2005504513A
(ja)
|
2001-05-09 |
2005-02-17 |
コリクサ コーポレイション |
前立腺癌の治療及び診断のための組成物及び方法
|
US20050196765A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint Kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
US20050209180A1
(en)
*
|
2001-05-18 |
2005-09-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
|
US20050164966A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of type 1 insulin-like growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050233344A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA)
|
US20050182006A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc |
RNA interference mediated inhibition of protein kinase C alpha (PKC-alpha) gene expression using short interfering nucleic acid (siNA)
|
US20050227935A1
(en)
*
|
2001-05-18 |
2005-10-13 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TNF and TNF receptor gene expression using short interfering nucleic acid (siNA)
|
US20050182007A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
US20080188430A1
(en)
*
|
2001-05-18 |
2008-08-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
|
US20050176665A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hairless (HR) gene expression using short interfering nucleic acid (siNA)
|
US20050176666A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GPRA and AAA1 gene expression using short interfering nucleic acid (siNA)
|
US20050153914A1
(en)
*
|
2001-05-18 |
2005-07-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of MDR P-glycoprotein gene expression using short interfering nucleic acid (siNA)
|
US20050124568A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of acetyl-CoA-carboxylase gene expression using short interfering nucleic acid (siNA)
|
US20070042983A1
(en)
*
|
2001-05-18 |
2007-02-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20050136436A1
(en)
*
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of G72 and D-amino acid oxidase (DAAO) gene expression using short interfering nucleic acid (siNA)
|
US20040006035A1
(en)
*
|
2001-05-29 |
2004-01-08 |
Dennis Macejak |
Nucleic acid mediated disruption of HIV fusogenic peptide interactions
|
US20050124566A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
|
US20050288242A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
|
US20050191638A1
(en)
*
|
2002-02-20 |
2005-09-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
|
US20050222066A1
(en)
*
|
2001-05-18 |
2005-10-06 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US7517864B2
(en)
*
|
2001-05-18 |
2009-04-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050196767A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
|
US20060241075A1
(en)
*
|
2001-05-18 |
2006-10-26 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)
|
US20040219671A1
(en)
*
|
2002-02-20 |
2004-11-04 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of parkinson disease using short interfering nucleic acid (siNA)
|
US20070270579A1
(en)
*
|
2001-05-18 |
2007-11-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20050256068A1
(en)
*
|
2001-05-18 |
2005-11-17 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of stearoyl-CoA desaturase (SCD) gene expression using short interfering nucleic acid (siNA)
|
US20040019001A1
(en)
*
|
2002-02-20 |
2004-01-29 |
Mcswiggen James A. |
RNA interference mediated inhibition of protein typrosine phosphatase-1B (PTP-1B) gene expression using short interfering RNA
|
US20050203040A1
(en)
*
|
2001-05-18 |
2005-09-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
US20030124513A1
(en)
*
|
2001-05-29 |
2003-07-03 |
Mcswiggen James |
Enzymatic nucleic acid treatment of diseases or conditions related to levels of HIV
|
US20050153915A1
(en)
*
|
2001-05-18 |
2005-07-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of early growth response gene expression using short interfering nucleic acid (siNA)
|
US20050124567A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TRPM7 gene expression using short interfering nucleic acid (siNA)
|
US20050119212A1
(en)
*
|
2001-05-18 |
2005-06-02 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of FAS and FASL gene expression using short interfering nucleic acid (siNA)
|
US20050159382A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
US20060019913A1
(en)
*
|
2001-05-18 |
2006-01-26 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibtion of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA)
|
US20050159376A1
(en)
*
|
2002-02-20 |
2005-07-21 |
Slrna Therapeutics, Inc. |
RNA interference mediated inhibition 5-alpha reductase and androgen receptor gene expression using short interfering nucleic acid (siNA)
|
US20060142226A1
(en)
*
|
2001-05-18 |
2006-06-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cholesteryl ester transfer protein (CETP) gene expression using short interfering nucleic acid (siNA)
|
US20050143333A1
(en)
*
|
2001-05-18 |
2005-06-30 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
|
EP3231445A1
(fr)
|
2001-05-18 |
2017-10-18 |
Sirna Therapeutics, Inc. |
Conjugués et compositions pour la fourniture cellulaire
|
US20050282188A1
(en)
*
|
2001-05-18 |
2005-12-22 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20030170891A1
(en)
*
|
2001-06-06 |
2003-09-11 |
Mcswiggen James A. |
RNA interference mediated inhibition of epidermal growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050159380A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of angiopoietin gene expression using short interfering nucleic acid (siNA)
|
US20050176664A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cholinergic muscarinic receptor (CHRM3) gene expression using short interfering nucleic acid (siNA)
|
US20060142225A1
(en)
*
|
2001-05-18 |
2006-06-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)
|
US20050164968A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of ADAM33 gene expression using short interfering nucleic acid (siNA)
|
US20050137155A1
(en)
*
|
2001-05-18 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of Parkinson disease using short interfering nucleic acid (siNA)
|
US7109165B2
(en)
*
|
2001-05-18 |
2006-09-19 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
US20050080031A1
(en)
*
|
2001-05-18 |
2005-04-14 |
Sirna Therapeutics, Inc. |
Nucleic acid treatment of diseases or conditions related to levels of Ras, HER2 and HIV
|
US20050079610A1
(en)
*
|
2001-05-18 |
2005-04-14 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA)
|
US20050159379A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc |
RNA interference mediated inhibition of gastric inhibitory polypeptide (GIP) and gastric inhibitory polypeptide receptor (GIPR) gene expression using short interfering nucleic acid (siNA)
|
US20060211642A1
(en)
*
|
2001-05-18 |
2006-09-21 |
Sirna Therapeutics, Inc. |
RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA)
|
US20050054596A1
(en)
*
|
2001-11-30 |
2005-03-10 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050287128A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
|
US20050187174A1
(en)
*
|
2001-05-18 |
2005-08-25 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA)
|
US20050164224A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
|
US9994853B2
(en)
|
2001-05-18 |
2018-06-12 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
US20050014172A1
(en)
*
|
2002-02-20 |
2005-01-20 |
Ivan Richards |
RNA interference mediated inhibition of muscarinic cholinergic receptor gene expression using short interfering nucleic acid (siNA)
|
US20050164967A1
(en)
*
|
2001-05-18 |
2005-07-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA)
|
US20030175950A1
(en)
*
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
US20050148530A1
(en)
*
|
2002-02-20 |
2005-07-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20050182009A1
(en)
*
|
2001-05-18 |
2005-08-18 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of NF-Kappa B / REL-A gene expression using short interfering nucleic acid (siNA)
|
US20050054598A1
(en)
*
|
2002-02-20 |
2005-03-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition hairless (HR) gene expression using short interfering nucleic acid (siNA)
|
US20050267058A1
(en)
*
|
2001-05-18 |
2005-12-01 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (sINA)
|
US20040198682A1
(en)
*
|
2001-11-30 |
2004-10-07 |
Mcswiggen James |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (siNA)
|
US20050233997A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
|
US20080161256A1
(en)
*
|
2001-05-18 |
2008-07-03 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
|
US20050119211A1
(en)
*
|
2001-05-18 |
2005-06-02 |
Sirna Therapeutics, Inc. |
RNA mediated inhibition connexin gene expression using short interfering nucleic acid (siNA)
|
US20040209831A1
(en)
*
|
2002-02-20 |
2004-10-21 |
Mcswiggen James |
RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)
|
US20050130181A1
(en)
*
|
2001-05-18 |
2005-06-16 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)
|
US20030140362A1
(en)
*
|
2001-06-08 |
2003-07-24 |
Dennis Macejak |
In vivo models for screening inhibitors of hepatitis B virus
|
US7205399B1
(en)
|
2001-07-06 |
2007-04-17 |
Sirna Therapeutics, Inc. |
Methods and reagents for oligonucleotide synthesis
|
US20030148928A1
(en)
*
|
2001-07-20 |
2003-08-07 |
Leonid Beigelman |
Enzymatic nucleic acid peptide conjugates
|
WO2003013226A2
(fr)
*
|
2001-08-09 |
2003-02-20 |
Cibus Genetics |
Plantes non transgeniques resistant aux herbicides
|
US20050075304A1
(en)
*
|
2001-11-30 |
2005-04-07 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20040138163A1
(en)
*
|
2002-05-29 |
2004-07-15 |
Mcswiggen James |
RNA interference mediated inhibition of vascular edothelial growth factor and vascular edothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20070203333A1
(en)
*
|
2001-11-30 |
2007-08-30 |
Mcswiggen James |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US20030219775A1
(en)
*
|
2001-12-14 |
2003-11-27 |
Ward David C. |
Nucleic acid diagnostic reagents and methods for detecting nucleic acids, polynucleotides and oligonucleotides
|
EP2224012B1
(fr)
|
2001-12-17 |
2013-01-30 |
Corixa Corporation |
Compositions et procédés pour la thérapie et le diagnostic de maladies intestines inflammatoires
|
ATE469167T1
(de)
|
2002-02-06 |
2010-06-15 |
Vicor Technologies Inc |
Anti-infarkt-moleküle
|
US20050096284A1
(en)
*
|
2002-02-20 |
2005-05-05 |
Sirna Therapeutics, Inc. |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA)
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US20050137153A1
(en)
*
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
WO2003106476A1
(fr)
*
|
2002-02-20 |
2003-12-24 |
Sirna Therapeutics, Inc |
Inhibition d'une infection a enterocoques et de l'activite de la cytolysine induite par des acides nucleiques
|
US20050222064A1
(en)
*
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
AU2003207708A1
(en)
|
2002-02-20 |
2003-09-09 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of map kinase genes
|
EP1534729A2
(fr)
*
|
2002-02-26 |
2005-06-01 |
University of Utah Research Foundation |
Variantes du nedd4l associees a l'hypertension et au bourgeonnement viral
|
US20030195164A1
(en)
*
|
2002-04-16 |
2003-10-16 |
Veli-Matti Kahari |
Novel ribozyme and its use
|
US20040018520A1
(en)
*
|
2002-04-22 |
2004-01-29 |
James Thompson |
Trans-splicing enzymatic nucleic acid mediated biopharmaceutical and protein
|
US20030224435A1
(en)
*
|
2002-05-16 |
2003-12-04 |
Scott Seiwert |
Detection of abused substances and their metabolites using nucleic acid sensor molecules
|
US7655790B2
(en)
|
2002-07-12 |
2010-02-02 |
Sirna Therapeutics, Inc. |
Deprotection and purification of oligonucleotides and their derivatives
|
US6989442B2
(en)
*
|
2002-07-12 |
2006-01-24 |
Sirna Therapeutics, Inc. |
Deprotection and purification of oligonucleotides and their derivatives
|
CA2495478A1
(fr)
|
2002-08-05 |
2004-02-12 |
University Of Rochester |
Proteines chimeres a domaine de transduction proteique/domaine desaminase, composes associes et utilisations correspondantes
|
US7923547B2
(en)
|
2002-09-05 |
2011-04-12 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
EP1581648A2
(fr)
*
|
2002-09-09 |
2005-10-05 |
Nura, Inc. |
Recepteurs couples a la proteine g et leurs utilisations
|
US20080260744A1
(en)
*
|
2002-09-09 |
2008-10-23 |
Omeros Corporation |
G protein coupled receptors and uses thereof
|
AU2003288906C1
(en)
*
|
2002-09-20 |
2010-12-09 |
Yale University |
Riboswitches, methods for their use, and compositions for use with riboswitches.
|
US9233120B2
(en)
|
2002-11-15 |
2016-01-12 |
Jyant Technologies |
Anti-CCL25 and anti-CCR9 antibodies for the prevention and treatment of cancer and cancer cell migration
|
US8512701B2
(en)
|
2002-11-15 |
2013-08-20 |
Morehouse School Of Medicine |
Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration
|
US8658377B2
(en)
|
2002-11-15 |
2014-02-25 |
Morehouse School Of Medicine |
Detecting cancer with anti-CCL25 and anti-CCR9 antibodies
|
US9487823B2
(en)
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
US20040231231A1
(en)
*
|
2002-12-20 |
2004-11-25 |
Cataldo Dominic A. |
Use of colloidal clays for sustained release of active ingredients
|
US20030232400A1
(en)
*
|
2002-12-20 |
2003-12-18 |
Susan Radka |
Methods of screening subjects for expression of soluble receptors of vascular endothelial growth factor (VEGF) for use in managing treatment and determining prognostic outcome
|
US8043834B2
(en)
|
2003-03-31 |
2011-10-25 |
Qiagen Gmbh |
Universal reagents for rolling circle amplification and methods of use
|
WO2004093788A2
(fr)
*
|
2003-04-17 |
2004-11-04 |
The Trustees Of Columbia University In The City Ofnew York |
Desmogleine 4, nouveau gene de la croissance des cheveux
|
US20050287668A1
(en)
*
|
2003-11-04 |
2005-12-29 |
Cell Therapeutics, Inc. (Cti) |
RNA interference compositions and screening methods for the identification of novel genes and biological pathways
|
WO2005078848A2
(fr)
*
|
2004-02-11 |
2005-08-25 |
University Of Tennessee Research Foundation |
Inhibition de la croissance et de l'invasion tumorales au moyen d'adnzymes de metalloproteinases anti-matricielles
|
ES2423060T3
(es)
|
2004-03-12 |
2013-09-17 |
Alnylam Pharmaceuticals, Inc. |
Agentes iRNA que tienen como diana al VEGF
|
MXPA06012076A
(es)
*
|
2004-04-20 |
2007-01-25 |
Nastech Pharm Co |
Metodos y composiciones para mejorar el suministro de arn bicatenario o un acido nucleico hibrido bicatenario para regular la expresion genetica en celulas de mamifero.
|
WO2005105157A2
(fr)
|
2004-04-23 |
2005-11-10 |
The Trustees Of Columbia University In The City Ofnew York |
Inhibition d'un arnm associe a une proteine du gene hairless (sans poil)
|
US20060040882A1
(en)
*
|
2004-05-04 |
2006-02-23 |
Lishan Chen |
Compostions and methods for enhancing delivery of nucleic acids into cells and for modifying expression of target genes in cells
|
US10508277B2
(en)
|
2004-05-24 |
2019-12-17 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
AU2005272920B2
(en)
|
2004-08-10 |
2011-05-12 |
Institute For Multiple Myeloma And Bone Cancer Research |
Methods of regulating differentiation and treating of multiple myeloma
|
US8129124B2
(en)
|
2005-02-02 |
2012-03-06 |
The Uab Research Foundation |
Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists
|
JP4528154B2
(ja)
*
|
2005-02-25 |
2010-08-18 |
株式会社クボタ |
田植機用の苗植付け機構
|
EA037929B1
(ru)
|
2005-03-23 |
2021-06-08 |
Генмаб А/С |
Антитела к cd38 человека и их применение
|
US7476733B2
(en)
|
2005-03-25 |
2009-01-13 |
The United States Of America As Represented By The Department Of Health And Human Services |
Development of a real-time PCR assay for detection of pneumococcal DNA and diagnosis of pneumococccal disease
|
DK1866414T3
(da)
|
2005-03-31 |
2012-04-23 |
Calando Pharmaceuticals Inc |
Inhibitorer af ribonukleotidreduktase-underenhed 2 og anvendelser deraf.
|
US8309303B2
(en)
|
2005-04-01 |
2012-11-13 |
Qiagen Gmbh |
Reverse transcription and amplification of RNA with simultaneous degradation of DNA
|
US20060234973A1
(en)
*
|
2005-04-14 |
2006-10-19 |
Kevin Fitzgerald |
Transcription factor RNA interference reagents and methods of use thereof
|
US20100129288A1
(en)
*
|
2005-06-28 |
2010-05-27 |
Elior Peles |
Gliomedin, Fragments Thereof and Methods of Using Same
|
EP1896586A2
(fr)
|
2005-06-28 |
2008-03-12 |
Medtronic, Inc. |
Procedes et sequences permettant de supprimer de maniere preferentielle l'expression de la huntingtine mutee
|
US20090176725A1
(en)
*
|
2005-08-17 |
2009-07-09 |
Sirna Therapeutics Inc. |
Chemically modified short interfering nucleic acid molecules that mediate rna interference
|
EP1762627A1
(fr)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Procédé pour l'activation d'acides nucléiques pour effectuer une réaction d'une polymérase
|
AU2006302245A1
(en)
*
|
2005-10-06 |
2007-04-19 |
Emthrax, Llc |
Methods and compositions relating to anthrax spore glycoproteins as vaccines
|
US8080534B2
(en)
|
2005-10-14 |
2011-12-20 |
Phigenix, Inc |
Targeting PAX2 for the treatment of breast cancer
|
WO2007047512A2
(fr)
|
2005-10-14 |
2007-04-26 |
Musc Foundation For Research Development |
Ciblage de pax2 en vue d'induire le traitement du cancer et l'immunite tumorale induite par defb1
|
US8313901B2
(en)
*
|
2005-12-21 |
2012-11-20 |
Yale University |
Methods and compositions related to the modulation of riboswitches
|
FI20055712A0
(fi)
*
|
2005-12-29 |
2005-12-29 |
Wallac Oy |
Makrosykliset oligonukleotiidien leimausreagenssit ja niistä johdetut konjugaatit
|
SI2465341T1
(sl)
*
|
2006-01-12 |
2015-04-30 |
Cibus Europe B.V. |
Mutantni epsps
|
ES2550099T3
(es)
|
2006-01-27 |
2015-11-04 |
Biogen Ma Inc. |
Antagonistas del receptor Nogo
|
NZ587704A
(en)
*
|
2006-03-31 |
2012-04-27 |
Alnylam Pharmaceuticals Inc |
Use of dsRNA for inhibiting expression of Eg5 gene
|
WO2007117657A2
(fr)
|
2006-04-07 |
2007-10-18 |
The Research Foundation Of State University Of New York |
Polypeptides du récepteur de la transcobalamine, acides nucléiques et modulateurs associés, procédés d'utilisation associés destinés à moduler la croissance cellulaire et à traiter le cancer et la déficience en cobalamine
|
WO2007128874A1
(fr)
*
|
2006-05-05 |
2007-11-15 |
Wallac Oy |
Réactifs de marquage de biomolécules à base d'azacycloalcanes et leurs conjugués dérivés
|
US8598333B2
(en)
*
|
2006-05-26 |
2013-12-03 |
Alnylam Pharmaceuticals, Inc. |
SiRNA silencing of genes expressed in cancer
|
CA2982638A1
(fr)
*
|
2006-06-28 |
2008-01-03 |
Nucelis Inc. |
Melanges d'acides gras et leurs utilisations
|
EP2061799A4
(fr)
*
|
2006-09-11 |
2010-12-22 |
Univ Yale |
Riborégulateurs lysine, mise au point d'un composé structural présentant des riborégulateurs lysine, et méthodes d'utilisation et compositions utilisables avec des riborégulateurs lysine
|
AU2007297535C1
(en)
|
2006-09-21 |
2017-11-23 |
University Of Florida Research Foundation, Inc. |
Compositions and methods related to protein displacement therapy for myotonic distrophy
|
US9074205B2
(en)
*
|
2006-10-18 |
2015-07-07 |
Marina Biotech, Inc. |
Nicked or gapped nucleic acid molecules and uses thereof
|
WO2008052774A2
(fr)
|
2006-10-31 |
2008-05-08 |
Noxxon Pharma Ag |
Procédé de détection d'un acide nucléique simple brin ou double brin
|
WO2008136852A2
(fr)
|
2006-11-01 |
2008-11-13 |
University Of Rochester |
Méthodes et compositions se rapportant à la structure et à la fonction de apobec3g
|
CA2672297A1
(fr)
|
2006-12-11 |
2008-06-19 |
University Of Utah Research Foundation |
Compositions et methodes de traitement de l'angiogenese pathologique et de la permeabilite vasculaire
|
WO2008109357A1
(fr)
*
|
2007-03-02 |
2008-09-12 |
Mdrna, Inc. |
Composés d'acide nucléique permettant d'inhiber l'expression de gène apob et utilisations de ceux-ci
|
JP2010519905A
(ja)
*
|
2007-03-02 |
2010-06-10 |
エムディーアールエヌエー,インコーポレイテッド |
Akt遺伝子の発現を抑制するための核酸化合物およびその使用
|
WO2008109361A1
(fr)
*
|
2007-03-02 |
2008-09-12 |
Mdrna, Inc, |
Composés d'acide nucléique permettant d'inhiber l'expression de gène de la famille erbb et utilisations de ceux-ci
|
US20100055784A1
(en)
*
|
2007-03-02 |
2010-03-04 |
Mdrna, Inc. |
Nucleic acid compounds for inhibiting wnt gene expression and uses thereof
|
WO2008109362A1
(fr)
*
|
2007-03-02 |
2008-09-12 |
Mdrna, Inc. |
Composés d'acide nucléique permettant d'inhiber l'expression de gène vegf et utilisations de ceux-ci
|
US20100105134A1
(en)
*
|
2007-03-02 |
2010-04-29 |
Mdrna, Inc. |
Nucleic acid compounds for inhibiting gene expression and uses thereof
|
JP2010519910A
(ja)
*
|
2007-03-02 |
2010-06-10 |
エムディーアールエヌエー,インコーポレイテッド |
Bcl2遺伝子の発現を抑制するための核酸化合物およびその使用
|
JP2010519908A
(ja)
*
|
2007-03-02 |
2010-06-10 |
エムディーアールエヌエー,インコーポレイテッド |
Hif1a遺伝子の発現を抑制するための核酸化合物およびその使用
|
WO2008109377A1
(fr)
*
|
2007-03-02 |
2008-09-12 |
Mdrna, Inc. |
Composés d'acide nucléique permettant d'inhiber l'expression de gène de la famille vegf et utilisations de ceux-ci
|
US20100055782A1
(en)
*
|
2007-03-02 |
2010-03-04 |
Mdrna, Inc. |
Nucleic acid compounds for inhibiting myc gene expression and uses thereof
|
EP2191001B1
(fr)
|
2007-04-09 |
2016-06-08 |
University of Florida Research Foundation, Inc. |
Compositions à base de vecteurs raav comprenant des protéines de capside modifiées par la tyrosine et procédés d'utilisation correspondants
|
MX2009011218A
(es)
*
|
2007-04-17 |
2010-02-11 |
Baxter Int |
Microparticulas de acido nucleico para administracion pulmonar.
|
ES2531520T3
(es)
|
2007-05-04 |
2015-03-16 |
Marina Biotech, Inc. |
Lipoaminoácidos y usos de los mismos
|
US20100150924A1
(en)
*
|
2007-05-22 |
2010-06-17 |
Elior Peles |
Regulation of myelination by nectin-like (necl) molecules
|
EP2426219A1
(fr)
*
|
2007-05-29 |
2012-03-07 |
Yale University |
Riborégulateurs (riboswitches) et procédés et compositions à utiliser avec les riborégulateurs
|
WO2008150884A1
(fr)
*
|
2007-05-29 |
2008-12-11 |
Yale University |
Procédés et compositions liés à des ribointerrupteurs qui régulent l'épissage alternatif et le traitement d'arn
|
EP2195331B1
(fr)
|
2007-08-28 |
2013-11-20 |
Uab Research Foundation |
Polypeptides de synthèse imitant l'apolipoprotéine e et leurs procédés d'utilisation
|
US8557767B2
(en)
|
2007-08-28 |
2013-10-15 |
Uab Research Foundation |
Synthetic apolipoprotein E mimicking polypeptides and methods of use
|
WO2009033027A2
(fr)
*
|
2007-09-05 |
2009-03-12 |
Medtronic, Inc. |
Suppression de l'expression et/ou de la fonction du gène scn9a pour le traitement de la douleur
|
AU2008308530A1
(en)
|
2007-10-05 |
2009-04-09 |
Cibus Europe B.V. |
Mutated acetohydroxyacid synthase genes in Brassica
|
US8501912B2
(en)
*
|
2007-12-03 |
2013-08-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Filipil compositions and methods for treating cancer
|
AU2008333811B2
(en)
|
2007-12-04 |
2014-05-01 |
Alnylam Pharmaceuticals, Inc. |
Carbohydrate conjugates as delivery agents for oligonucleotides
|
CA2710767C
(fr)
*
|
2007-12-27 |
2016-09-27 |
Cibus Llc |
Melanges d'acides gras et d'esters d'alkyle et leurs utilisations
|
EP3100718B1
(fr)
|
2008-01-02 |
2019-11-27 |
Arbutus Biopharma Corporation |
Compositions améliorées et procédés d'administration d'acides nucléiques
|
EP2262489A2
(fr)
*
|
2008-02-28 |
2010-12-22 |
Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts |
Nano-particles creux et leur utilisations
|
EP2712926A2
(fr)
*
|
2008-03-05 |
2014-04-02 |
Alnylam Pharmaceuticals, Inc. |
Compositions et procédés d'inhibition d'expression des gènes Eg5 et VEGF
|
US20090233993A1
(en)
*
|
2008-03-06 |
2009-09-17 |
Burnham Institute For Medical Research |
Compositions and methods for inhibiting gsk3 activity and uses thereof
|
JP2011516065A
(ja)
|
2008-04-04 |
2011-05-26 |
カランド ファーマシューティカルズ, インコーポレイテッド |
Epas1阻害剤の組成物および使用
|
NZ588583A
(en)
|
2008-04-15 |
2012-08-31 |
Protiva Biotherapeutics Inc |
Novel lipid formulations for nucleic acid delivery
|
US20110262395A1
(en)
|
2008-05-08 |
2011-10-27 |
University Of Utah Research Foundation |
Sensory receptors for chronic fatigue and pain and uses thereof
|
WO2009143490A1
(fr)
|
2008-05-23 |
2009-11-26 |
Cibus International, L.P. |
Production de squalène en utilisant une levure
|
WO2009155100A1
(fr)
|
2008-05-30 |
2009-12-23 |
Yale University |
Compositions oligonucléotidiques ciblées pour modifier l'expression génique
|
US20100015708A1
(en)
*
|
2008-06-18 |
2010-01-21 |
Mdrna, Inc. |
Ribonucleic acids with non-standard bases and uses thereof
|
WO2010011347A2
(fr)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Inhibiteurs de clip et procédés de modulation de la fonction immune
|
WO2010039801A2
(fr)
|
2008-10-02 |
2010-04-08 |
The J. David Gladstone Institutes |
Méthodes de traitement d’une infection par le virus de l’hépatite c
|
ES2475065T3
(es)
|
2008-10-09 |
2014-07-10 |
Tekmira Pharmaceuticals Corporation |
Aminol�pidos mejorados y métodos para la administración de ácidos nucleicos
|
KR20110071017A
(ko)
|
2008-10-16 |
2011-06-27 |
마리나 바이오테크, 인크. |
유전자 침묵 치료제의 리포좀에 의한 효율적인 전달을 위한 프로세스 및 조성물
|
ES2631507T3
(es)
|
2008-10-29 |
2017-08-31 |
China Synthetic Rubber Corporation |
Procedimientos y agentes para el diagnóstico y tratamiento del carcinoma hepatocelular
|
KR20220150995A
(ko)
|
2008-11-10 |
2022-11-11 |
알닐람 파마슈티칼스 인코포레이티드 |
치료제 운반용 신규 지질 및 조성물
|
US20120070443A1
(en)
|
2008-12-02 |
2012-03-22 |
University Of Utah Research Foundation |
Pde1 as a target therapeutic in heart disease
|
EP3243504A1
(fr)
|
2009-01-29 |
2017-11-15 |
Arbutus Biopharma Corporation |
Formulation lipidique améliorée
|
WO2010096813A1
(fr)
|
2009-02-23 |
2010-08-26 |
New York Blood Center |
Facteurs de transcription de type krüppel et régulation des graisses
|
US20120149756A1
(en)
|
2009-04-10 |
2012-06-14 |
Associatin Institut de Myologie |
Tricyclo-dna antisense oligonucleotides, compositions, and methods for the treatment of disease
|
EP2419143B8
(fr)
|
2009-04-13 |
2018-06-27 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Particules hpv et utilisations associées
|
CA3042927C
(fr)
|
2009-05-05 |
2022-05-17 |
Arbutus Biopharma Corporation |
Compositions de lipides servant a distribuer des agents therapeutiques
|
US20100285112A1
(en)
|
2009-05-05 |
2010-11-11 |
Tatiana Novobrantseva |
Methods of delivering oligonucleotides to immune cells
|
KR102205886B1
(ko)
|
2009-06-10 |
2021-01-21 |
알닐람 파마슈티칼스 인코포레이티드 |
향상된 지질 조성물
|
WO2011000107A1
(fr)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Formulations lipidiques inédites permettant l'administration d'agents thérapeutiques en direction de tumeurs solides
|
US20110060000A1
(en)
|
2009-09-10 |
2011-03-10 |
Maurizio Grimaldi |
Acridine analogs in the treatment of gliomas
|
WO2011039646A2
(fr)
|
2009-09-30 |
2011-04-07 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Ciblage de particules d'administration de gène de papillomavirus
|
US8450090B2
(en)
|
2009-10-06 |
2013-05-28 |
The Regents Of The University Of Colorado, A Body Corporate |
Compositions and methods for promoting fatty acid production in plants
|
EP3219815B1
(fr)
*
|
2009-11-23 |
2019-10-02 |
Cibus Europe B.V. |
Procédés et compositions de production de squalène au moyen de la levure
|
WO2011071860A2
(fr)
|
2009-12-07 |
2011-06-16 |
Alnylam Pharmaceuticals, Inc. |
Compositions utilisées pour l'administration d'acides nucléiques
|
WO2011075656A1
(fr)
|
2009-12-18 |
2011-06-23 |
The University Of British Columbia |
Procédés et compositions pour l'administration d'acides nucléiques
|
MX2012009318A
(es)
|
2010-02-10 |
2012-09-07 |
Novartis Ag |
Metodos y compuestos para el crecimiento muscular.
|
CA2785529C
(fr)
*
|
2010-02-11 |
2019-01-08 |
Nanostring Technologies, Inc. |
Compositions et procedes de detection de petits arn
|
US20110207789A1
(en)
|
2010-02-19 |
2011-08-25 |
Ye Fang |
Methods related to casein kinase ii (ck2) inhibitors and the use of purinosome-disrupting ck2 inhibitors for anti-cancer therapy agents
|
WO2011119842A1
(fr)
|
2010-03-25 |
2011-09-29 |
The J. David Gladstone Institutes |
Compositions et procédés pour traiter des troubles neurologiques
|
WO2011120023A1
(fr)
|
2010-03-26 |
2011-09-29 |
Marina Biotech, Inc. |
Composés d'acide nucléique pour inhiber l'expression de gène de survivine et utilisations de ceux-ci
|
WO2011133584A2
(fr)
|
2010-04-19 |
2011-10-27 |
Marina Biotech, Inc. |
Composés de type acide nucléique pour inhiber l'expression du gène hras et leurs utilisations
|
PT2561067T
(pt)
|
2010-04-23 |
2019-02-04 |
Univ Florida |
Composições de ciclase raav-guanilato e métodos para tratar a amaurose congénita 1 de leber (acl1)
|
EP2563922A1
(fr)
|
2010-04-26 |
2013-03-06 |
Marina Biotech, Inc. |
Composés d'acide nucléique ayant des monomères à conformation restreinte et leurs utilisations
|
WO2011139843A2
(fr)
|
2010-04-28 |
2011-11-10 |
Marina Biotech, Inc. |
Compositions multi-siarn pour la réduction de l'expression génique
|
WO2012006506A1
(fr)
|
2010-07-09 |
2012-01-12 |
Massachusetts Institute Of Technology |
Genès, enzymes et flux constituant des cibles métaboliques pour la thérapie contre le cancer
|
WO2012016184A2
(fr)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Procédés et compositions pour la délivrance d'agents actifs
|
WO2012016188A2
(fr)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Procédés et compositions pour l'administration d'agents actifs
|
UA112969C2
(uk)
|
2010-08-03 |
2016-11-25 |
Сібас Юс Ллс |
Рослина, стійка до одного або більше ррх-інгібуючих гербіцидів, яка містить мутантний ген протопорфіриноген ix оксидази (ррх)
|
US20120122223A1
(en)
|
2010-08-03 |
2012-05-17 |
Cibus Us Llc |
Mutated protoporphyrinogen ix oxidase (ppx) genes
|
KR20130137160A
(ko)
|
2010-08-24 |
2013-12-16 |
머크 샤프 앤드 돔 코포레이션 |
내부의 비-핵산 스페이서를 함유하는 단일-가닥 RNAi 작용제
|
WO2012044992A2
(fr)
|
2010-09-30 |
2012-04-05 |
Agency For Science, Technology And Research (A*Star) |
Méthodes et réactifs de détection et de traitement de la métaplasie œsophagienne
|
EP3327125B1
(fr)
|
2010-10-29 |
2020-08-05 |
Sirna Therapeutics, Inc. |
Inhibition au moyen d'interférence arn d'une expression de gène utilisant des acides nucléiques à petit interférent (sina)
|
AU2012207606B2
(en)
|
2011-01-11 |
2017-02-23 |
Alnylam Pharmaceuticals, Inc. |
Pegylated lipids and their use for drug delivery
|
CN104136451A
(zh)
|
2011-09-07 |
2014-11-05 |
玛瑞纳生物技术有限公司 |
具有构象限制的单体的核酸化合物的合成和用途
|
JP6250543B2
(ja)
|
2011-09-27 |
2017-12-20 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
ジ脂肪族置換peg化脂質
|
KR20140082796A
(ko)
|
2011-10-14 |
2014-07-02 |
제넨테크, 인크. |
항-HtrA1 항체 및 사용 방법
|
JP2015502365A
(ja)
|
2011-12-12 |
2015-01-22 |
オンコイミューニン,インコーポレイティド |
オリゴヌクレオチドのイン−ビボ送達
|
EP2797948B1
(fr)
|
2011-12-27 |
2019-02-20 |
The J. David Gladstone Institutes |
Compositions pour l'utilisation dans la régulation du métabolisme du glucose
|
US9700639B2
(en)
|
2012-02-07 |
2017-07-11 |
Aura Biosciences, Inc. |
Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
|
RU2020111326A
(ru)
|
2012-02-24 |
2020-04-29 |
Протива Байотерапьютикс Инк. |
Триалкил катионные липиды и способы их использования
|
KR101520383B1
(ko)
|
2012-08-02 |
2015-05-15 |
에이비온 주식회사 |
Hpv 감염과 관련된 암의 치료용 조성물
|
WO2014153178A2
(fr)
|
2013-03-14 |
2014-09-25 |
Cibus Us Llc |
Gènes d'oxyde d'allène synthase 2 (aos2) mutés
|
US9957515B2
(en)
|
2013-03-15 |
2018-05-01 |
Cibus Us Llc |
Methods and compositions for targeted gene modification
|
US11434494B2
(en)
|
2013-03-15 |
2022-09-06 |
Cibus Us Llc |
Targeted gene modification using oligonucleotide-mediated gene repair
|
EP2966980A4
(fr)
|
2013-03-15 |
2016-12-28 |
Cibus Us Llc |
Procédés et compositions destinés à augmenter l'efficacité de l'efficacité augmentée de la modification de gène ciblé au moyen de la réparation de gène médiée par un oligonucléotide
|
CN105283561A
(zh)
|
2013-04-04 |
2016-01-27 |
佐治亚州立大学研究基金会公司 |
使用纳米粒子辅助信号放大的rna微芯片检测
|
WO2015006740A2
(fr)
|
2013-07-11 |
2015-01-15 |
Alnylam Pharmaceuticals, Inc. |
Conjugués ligands d'oligonucléotides et procédé pour leur préparation
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
ES2917573T3
(es)
|
2013-09-18 |
2022-07-08 |
Aura Biosciences Inc |
Método de producción de moléculas fotosensibles
|
WO2015074010A2
(fr)
|
2013-11-18 |
2015-05-21 |
Beth Israel Deaconess Medical Center, Inc. |
Compositions et méthode de régénération pulmonaire
|
EP3116305B1
(fr)
|
2014-03-14 |
2023-12-06 |
Cibus US LLC |
Procédés et compositions permettant d'améliorer l'efficacité de modifications génétiques ciblées en utilisant la réparation de gène médiée par des oligonucléotides
|
AU2015298571B2
(en)
|
2014-07-30 |
2020-09-03 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
BR112017001860A2
(pt)
|
2014-07-31 |
2018-02-27 |
Uab Research Foundation |
peptídeo sintético, composição farmacêutica, métodos, regime de dosagem, e, anticorpo monoclonal
|
WO2016061131A1
(fr)
|
2014-10-14 |
2016-04-21 |
The J. David Gladstone Institutes |
Compositions et procédés pour réactiver un virus d'immunodéficience latent
|
US10723794B2
(en)
|
2015-03-18 |
2020-07-28 |
University Of South Carolina |
Anti-CcL8 antibodies and uses thereof
|
EP3331536A4
(fr)
|
2015-08-03 |
2019-03-27 |
The Regents of The University of California |
Compositions et procédés pour moduler l'activité d'abhd2
|
EP3368656A4
(fr)
|
2015-10-30 |
2019-07-17 |
The United States of America, as represented by the secretary, Department of Health and Human Services |
Thérapie anticancéreuse ciblée
|
KR102162324B1
(ko)
|
2015-10-30 |
2020-10-07 |
제넨테크, 인크. |
항-HtrA1 항체 및 이의 사용 방법
|
JP2019506170A
(ja)
|
2016-02-09 |
2019-03-07 |
キブス ユーエス エルエルシー |
オリゴヌクレオチド介在性遺伝子修復を利用した標的遺伝子修飾の効率を上昇させるための方法および組成物
|
MA45349A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques egfr et leurs utilisations
|
MA45469A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques de bêta-caténine et leurs utilisations
|
MA45471A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques de phosphatidylinositol-3-kinase et leurs utilisations
|
MA45468A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques myc et utilisations
|
MA45470A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques kras et leurs utilisations
|
US10905710B2
(en)
|
2016-05-24 |
2021-02-02 |
Emory University |
Particles with RNA cleaving nucleobase polymers and uses for managing inflammatory disorders
|
WO2018026943A1
(fr)
|
2016-08-03 |
2018-02-08 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Agents thérapeutiques ciblant tlr9
|
CN109804066A
(zh)
|
2016-08-09 |
2019-05-24 |
哈佛大学的校长及成员们 |
可编程cas9-重组酶融合蛋白及其用途
|
WO2018119359A1
(fr)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Édition du gène récepteur ccr5 pour protéger contre l'infection par le vih
|
CA3049424A1
(fr)
|
2017-01-06 |
2018-07-12 |
Avidity Biosciences Llc |
Compositions d'acide nucleique-polypeptide et methodes d'induction de saut d'exon
|
WO2018165504A1
(fr)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Suppression de la douleur par édition de gène
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
JP2020534795A
(ja)
|
2017-07-28 |
2020-12-03 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
|
EP3676376A2
(fr)
|
2017-08-30 |
2020-07-08 |
President and Fellows of Harvard College |
Éditeurs de bases à haut rendement comprenant une gam
|
WO2019079347A1
(fr)
|
2017-10-16 |
2019-04-25 |
The Broad Institute, Inc. |
Utilisations d'éditeurs de bases adénosine
|
WO2019113393A1
(fr)
|
2017-12-06 |
2019-06-13 |
Avidity Biosciences Llc |
Compositions et procédés de traitement de l'atrophie musculaire et de la dystrophie myotonique
|
WO2019140009A1
(fr)
|
2018-01-09 |
2019-07-18 |
Cibus Us Llc |
Gènes de résistance à l'égrenage et mutations
|
MX2021007368A
(es)
|
2018-12-21 |
2021-07-15 |
Avidity Biosciences Inc |
Anticuerpos anti-receptor de transferrina y usos de los mismos.
|
WO2020191249A1
(fr)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Procédés et compositions pour l'édition de séquences nucléotidiques
|
KR20220053599A
(ko)
|
2019-08-14 |
2022-04-29 |
아퀴타스 테라퓨틱스 인크. |
핵산을 전달하기 위한 개선된 지질 나노입자
|
AU2021237465A1
(en)
|
2020-03-19 |
2022-10-13 |
Avidity Biosciences, Inc. |
Compositions and methods of treating Facioscapulohumeral muscular dystrophy
|
KR20220161378A
(ko)
|
2020-03-27 |
2022-12-06 |
어비디티 바이오사이언시스 인크. |
근이영양증의 치료용 조성물 및 방법
|
MX2022014008A
(es)
|
2020-05-08 |
2023-02-09 |
Broad Inst Inc |
Métodos y composiciones para la edición simultánea de ambas cadenas de una secuencia de nucleótidos de doble cadena objetivo.
|
WO2022097157A2
(fr)
|
2020-11-09 |
2022-05-12 |
1E Therapeutics, Ltd. |
Méthodes de traitement ou de prévention d'infections bactériennes faisant appel à une séquence catalytique
|
JP2024500804A
(ja)
|
2020-12-18 |
2024-01-10 |
イェダ リサーチ アンド ディベロップメント カンパニー リミテッド |
Chd2ハプロ不全の処置における使用のための組成物及びその同定方法
|
WO2022144883A2
(fr)
|
2020-12-28 |
2022-07-07 |
1E Therapeutics, Ltd. |
Arnm de p21 ciblant des dnazymes
|
IL304047A
(en)
|
2020-12-28 |
2023-08-01 |
1E Therapeutics Ltd |
Silencing target sites in the p21 mRNA sequence
|
IL307298A
(en)
|
2021-03-31 |
2023-11-01 |
Entrada Therapeutics Inc |
Cell-penetrating circular peptides
|
CA3218805A1
(fr)
|
2021-05-10 |
2022-11-17 |
Ziqing QIAN |
Compositions et methodes pour des agents therapeutiques intracellulaires
|
WO2022240760A2
(fr)
|
2021-05-10 |
2022-11-17 |
Entrada Therapeutics, Inc. |
Compositions et procédés de modulation de l'épissage d'arnm
|
WO2022240721A1
(fr)
|
2021-05-10 |
2022-11-17 |
Entrada Therapeutics, Inc. |
Compositions et méthodes de modulation de l'activité du facteur 5 de régulation de l'interféron (irf-5)
|
KR20240038967A
(ko)
|
2021-06-23 |
2024-03-26 |
엔트라다 테라퓨틱스, 인크. |
Cug 반복을 표적화하기 위한 안티센스 화합물 및 방법
|
WO2023014938A1
(fr)
|
2021-08-05 |
2023-02-09 |
Sanegene Bio Usa Inc. |
Dérivés de ribose modifiés par 1'-alkyle et procédés d'utilisation
|
AU2022345098A1
(en)
|
2021-09-16 |
2024-04-04 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
CA3233113A1
(fr)
|
2021-09-22 |
2023-03-30 |
Sanegene Bio Usa Inc. |
Derives de ribose modifies par 2'-alkyle ou 3'-alkyle destines a etre utilises dans l'administration in vivo d'oligonucleotides
|
US20230227480A1
(en)
|
2021-10-05 |
2023-07-20 |
Sanegene Bio Usa Inc. |
Polyhydroxylated cyclopentane derivatives and methods of use
|
WO2023144792A1
(fr)
|
2022-01-31 |
2023-08-03 |
Genevant Sciences Gmbh |
Conjugués poly(alkyloxazoline)-lipide et particules lipidiques les contenant
|
WO2023144798A1
(fr)
|
2022-01-31 |
2023-08-03 |
Genevant Sciences Gmbh |
Lipides cationiques ionisables pour nanoparticules lipidiques
|
US20230346819A1
(en)
|
2022-02-22 |
2023-11-02 |
Sanegene Bio Usa Inc. |
5'-modified carbocyclic ribonucleotide derivatives and methods of use
|
WO2024015796A1
(fr)
|
2022-07-11 |
2024-01-18 |
Sanegene Bio Usa Inc. |
Dérivés du ribose modifié en 2' optimisés et procédés d'utilisation
|