CA2031150A1 - Distributeurs de medicaments a liberation prolongee - Google Patents

Distributeurs de medicaments a liberation prolongee

Info

Publication number
CA2031150A1
CA2031150A1 CA2031150A CA2031150A CA2031150A1 CA 2031150 A1 CA2031150 A1 CA 2031150A1 CA 2031150 A CA2031150 A CA 2031150A CA 2031150 A CA2031150 A CA 2031150A CA 2031150 A1 CA2031150 A1 CA 2031150A1
Authority
CA
Canada
Prior art keywords
sustained
drug
dosage units
release
drug dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2031150A
Other languages
English (en)
Other versions
CA2031150C (fr
Inventor
Dale R. Brinker
Enrique D. Eveline
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27033923&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2031150(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CA2031150A1 publication Critical patent/CA2031150A1/fr
Application granted granted Critical
Publication of CA2031150C publication Critical patent/CA2031150C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002031150A 1989-12-01 1990-11-29 Distributeurs de medicaments a liberation prolongee Expired - Lifetime CA2031150C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US605,152 1984-04-30
US44445889A 1989-12-01 1989-12-01
US444,458 1989-12-01
US60515290A 1990-11-02 1990-11-02

Publications (2)

Publication Number Publication Date
CA2031150A1 true CA2031150A1 (fr) 1991-06-02
CA2031150C CA2031150C (fr) 2000-11-21

Family

ID=27033923

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002031150A Expired - Lifetime CA2031150C (fr) 1989-12-01 1990-11-29 Distributeurs de medicaments a liberation prolongee

Country Status (13)

Country Link
EP (1) EP0430287B2 (fr)
JP (1) JP3010562B2 (fr)
KR (1) KR100223131B1 (fr)
AT (1) ATE112678T1 (fr)
AU (1) AU623560B2 (fr)
CA (1) CA2031150C (fr)
DE (1) DE69013296T3 (fr)
DK (1) DK0430287T4 (fr)
ES (1) ES2065461T5 (fr)
GR (1) GR3034483T3 (fr)
IE (1) IE66116B1 (fr)
IL (1) IL96311A (fr)
PT (1) PT96046B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4127665A1 (de) * 1991-08-22 1993-02-25 Beiersdorf Ag Galenische matrix
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
JP3611456B2 (ja) * 1997-09-30 2005-01-19 日研化学株式会社 テオフィリン徐放性錠剤
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
KR20010101295A (ko) * 1998-12-18 2001-11-14 스티븐 에프. 웨인스톡 디발프로엑스 나트륨의 조절-방출성 제형물
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
US6419953B1 (en) 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
MXPA02004293A (es) 1999-10-29 2002-10-31 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada..
CN100518827C (zh) 2000-10-30 2009-07-29 欧罗赛铁克股份有限公司 控释氢可酮制剂
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
ES2308065T3 (es) * 2004-04-30 2008-12-01 Topotarget Germany Ag Formulacion que comprende un inhibidor de histona desacetilasa, que exhibe una liberacion bifasica.
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
KR100806541B1 (ko) * 2005-05-11 2008-02-26 한국유나이티드제약 주식회사 아세클로페낙을 함유하는 제어 방출성 제제
WO2009008004A2 (fr) * 2007-05-23 2009-01-15 Sun Pharmaceutical Industries Limited Formulations à libération prolongée de divalproex de sodium
EP2030613A1 (fr) * 2007-08-17 2009-03-04 Abbott GmbH & Co. KG Préparation de compositions avec essentiellement des antibiotiques macrolides intégrés non cristallins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963451A (en) † 1973-02-15 1976-06-15 United States Steel Corporation Method of forming a high-temperature abrasion-resistant coating on a ferrous metal substrate, and resulting article
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
FI63335B (fi) † 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
DK150008C (da) † 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
US4874614A (en) * 1985-03-25 1989-10-17 Abbott Laboratories Pharmaceutical tableting method
GB2186485B (en) † 1986-02-13 1988-09-07 Ethical Pharma Ltd Slow release formulation
IE63242B1 (en) * 1988-06-24 1995-04-05 Abbott Lab Pharmaceutical granules and tablets made therefrom

Also Published As

Publication number Publication date
ES2065461T5 (es) 2001-01-01
KR100223131B1 (ko) 1999-10-15
IL96311A0 (en) 1991-08-16
IL96311A (en) 1995-05-26
DE69013296T2 (de) 1995-02-23
ATE112678T1 (de) 1994-10-15
DE69013296T3 (de) 2000-11-09
AU623560B2 (en) 1992-05-14
GR3034483T3 (en) 2000-12-29
EP0430287A3 (en) 1991-08-21
CA2031150C (fr) 2000-11-21
EP0430287A2 (fr) 1991-06-05
JPH03190817A (ja) 1991-08-20
AU6764390A (en) 1991-02-14
ES2065461T3 (es) 1995-02-16
PT96046A (pt) 1991-09-13
IE904091A1 (en) 1991-06-05
KR910011243A (ko) 1991-08-07
DK0430287T3 (da) 1995-02-27
PT96046B (pt) 2001-09-27
EP0430287B1 (fr) 1994-10-12
IE66116B1 (en) 1995-12-13
DK0430287T4 (da) 2000-10-02
DE69013296D1 (de) 1994-11-17
JP3010562B2 (ja) 2000-02-21
EP0430287B2 (fr) 2000-07-12

Similar Documents

Publication Publication Date Title
CA2031150A1 (fr) Distributeurs de medicaments a liberation prolongee
ATE128863T1 (de) Arzneimittelformulierungen mit verzögerter wirkstoffabgabe.
DE59202537D1 (de) Feste pharmazeutische Retardform.
ATE202473T1 (de) Rasch freisetzende tablettenkerne mit unlöslichen arzneistoffen und mit einem retardüberzug
AU5895596A (en) Treatment of inflammatory bowel disease using oral dosage forms of omega-3 polyunsaturated acids
BG100933A (en) Polymer coated tablets comprising amoxycilin and clavulanate
AU1534699A (en) Osmotic dosage form comprising first and second coats
AU6770490A (en) Solid pharmaceutical compositions containing cimetidine
AU7534087A (en) Sustained release pharmaceutical compositions in oral dosage form
CA2226166A1 (fr) Nanoparticules biocompatibles et biodegradables concues pour l'absorption et la liberation de medicaments proteiniques
AU7452887A (en) Controlled absorption pharmaceutical composition
ATE246505T1 (de) Zubereitung enthaltend cefaclor oder cephalexin mit modifizierter freisetzungsmatrix
MY110660A (en) Pharmaceutical compositions containing nifedipine and process for the preparation thereof
CA2143413A1 (fr) Pellicule liberant un medicament localement pour le traitement periodontique
AU574220B2 (en) Sustained release drug in ter polymer coat (pvc and pvacand pvom)
CA2231176A1 (fr) Composition pour administration rectale a action de longue duree
EP0761209A3 (fr) Formulations de la ranitidine à libération commandée
AU1305999A (en) (+)-ephedrine as a sympathomimetic drug

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry