CA2029785C - Glutaric acid derivatives and preparations thereof - Google Patents

Glutaric acid derivatives and preparations thereof

Info

Publication number
CA2029785C
CA2029785C CA002029785A CA2029785A CA2029785C CA 2029785 C CA2029785 C CA 2029785C CA 002029785 A CA002029785 A CA 002029785A CA 2029785 A CA2029785 A CA 2029785A CA 2029785 C CA2029785 C CA 2029785C
Authority
CA
Canada
Prior art keywords
formula
salt
compound
optically pure
stereoisomeric form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002029785A
Other languages
English (en)
French (fr)
Other versions
CA2029785A1 (en
Inventor
Ian Tompson Barnish
Keith James
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd Great Britain
Original Assignee
Pfizer Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd Great Britain filed Critical Pfizer Ltd Great Britain
Publication of CA2029785A1 publication Critical patent/CA2029785A1/en
Application granted granted Critical
Publication of CA2029785C publication Critical patent/CA2029785C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA002029785A 1989-11-16 1990-11-13 Glutaric acid derivatives and preparations thereof Expired - Fee Related CA2029785C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898925933A GB8925933D0 (en) 1989-11-16 1989-11-16 Glutaric acid derivatives and preparation thereof
GB8925933.7 1989-11-16

Publications (2)

Publication Number Publication Date
CA2029785A1 CA2029785A1 (en) 1991-05-17
CA2029785C true CA2029785C (en) 1995-03-28

Family

ID=10666416

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002029785A Expired - Fee Related CA2029785C (en) 1989-11-16 1990-11-13 Glutaric acid derivatives and preparations thereof

Country Status (29)

Country Link
US (1) US5087732A (https=)
EP (1) EP0432898B1 (https=)
JP (1) JPH03176460A (https=)
KR (1) KR940005958B1 (https=)
CN (2) CN1028361C (https=)
AT (1) ATE104270T1 (https=)
AU (1) AU623814B2 (https=)
BR (1) BR9005746A (https=)
CA (1) CA2029785C (https=)
CZ (1) CZ284374B6 (https=)
DE (1) DE69008130T2 (https=)
DK (1) DK0432898T3 (https=)
EG (1) EG19319A (https=)
ES (1) ES2062410T3 (https=)
FI (1) FI107148B (https=)
GB (1) GB8925933D0 (https=)
HU (1) HU207711B (https=)
IE (1) IE63684B1 (https=)
IL (1) IL96299A (https=)
MX (1) MX23335A (https=)
MY (1) MY104782A (https=)
NO (1) NO179072C (https=)
NZ (1) NZ236080A (https=)
PH (1) PH27369A (https=)
PL (2) PL164610B1 (https=)
PT (1) PT95889B (https=)
RU (1) RU2002734C1 (https=)
SK (1) SK282272B6 (https=)
ZA (1) ZA909161B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208236A (en) * 1992-09-23 1993-05-04 Schering Corporation N-(acylaminomethyl)glutaryl amino acids and use
FR2890069B1 (fr) * 2005-08-31 2011-03-04 Senn Chemicals Internat Intermediaires de synthese pour la preparation de b2-aminoacides et leurs procedes de preparation
PT2380871E (pt) * 2010-04-15 2013-03-07 Indena Spa Um processo para a preparação de derivados de isoserina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
KR880007441A (ko) * 1986-12-11 1988-08-27 알렌 제이.스피겔 스피로-치환된 글루타르아미드 이뇨제
GB8820844D0 (en) * 1988-09-05 1988-10-05 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
CN1107135A (zh) 1995-08-23
IL96299A0 (en) 1991-08-16
ES2062410T3 (es) 1994-12-16
DE69008130D1 (de) 1994-05-19
NO904961L (no) 1991-05-21
JPH0585538B2 (https=) 1993-12-07
US5087732A (en) 1992-02-11
CZ568590A3 (cs) 1998-08-12
DE69008130T2 (de) 1994-07-21
FI107148B (fi) 2001-06-15
JPH03176460A (ja) 1991-07-31
NO904961D0 (no) 1990-11-15
BR9005746A (pt) 1991-07-30
CN1051991C (zh) 2000-05-03
HU907179D0 (en) 1991-05-28
KR940005958B1 (ko) 1994-06-25
CN1028361C (zh) 1995-05-10
KR910009635A (ko) 1991-06-28
IL96299A (en) 1997-11-20
HU207711B (en) 1993-05-28
HUT56536A (en) 1991-09-30
CA2029785A1 (en) 1991-05-17
CZ284374B6 (cs) 1998-11-11
NO179072B (no) 1996-04-22
PL287759A1 (en) 1991-11-04
ZA909161B (en) 1992-06-24
PL164543B1 (pl) 1994-08-31
GB8925933D0 (en) 1990-01-04
ATE104270T1 (de) 1994-04-15
SK568590A3 (en) 2001-12-03
IE63684B1 (en) 1995-05-31
NZ236080A (en) 1992-04-28
MX23335A (es) 1993-09-01
FI905664L (fi) 1991-05-17
AU6668490A (en) 1991-05-23
RU2002734C1 (ru) 1993-11-15
FI905664A0 (fi) 1990-11-15
PT95889A (pt) 1991-09-13
EP0432898B1 (en) 1994-04-13
PH27369A (en) 1993-06-21
PL164610B1 (pl) 1994-08-31
EG19319A (en) 1994-09-29
NO179072C (no) 1996-07-31
EP0432898A3 (en) 1991-09-11
DK0432898T3 (da) 1994-05-16
IE904121A1 (en) 1991-05-22
CN1051725A (zh) 1991-05-29
MY104782A (en) 1994-05-31
PT95889B (pt) 1997-06-30
AU623814B2 (en) 1992-05-21
EP0432898A2 (en) 1991-06-19
SK282272B6 (sk) 2001-12-03

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