CA1340296C - Cell growth regulatory factor - Google Patents

Cell growth regulatory factor

Info

Publication number
CA1340296C
CA1340296C CA000525706A CA525706A CA1340296C CA 1340296 C CA1340296 C CA 1340296C CA 000525706 A CA000525706 A CA 000525706A CA 525706 A CA525706 A CA 525706A CA 1340296 C CA1340296 C CA 1340296C
Authority
CA
Canada
Prior art keywords
cells
polypeptide
oncostatin
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000525706A
Other languages
English (en)
French (fr)
Inventor
Joyce M. Zarling
Mohammed Shoyab
Hans Marquardt
Marcia B. Hanson
Mario N. Lioubin
Thomas Joseph Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Application granted granted Critical
Publication of CA1340296C publication Critical patent/CA1340296C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA000525706A 1985-12-20 1986-12-18 Cell growth regulatory factor Expired - Lifetime CA1340296C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81123585A 1985-12-20 1985-12-20
US811,235 1985-12-20
US93528386A 1986-11-26 1986-11-26
US935,283 1986-11-26

Publications (1)

Publication Number Publication Date
CA1340296C true CA1340296C (en) 1998-12-29

Family

ID=27123452

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000525706A Expired - Lifetime CA1340296C (en) 1985-12-20 1986-12-18 Cell growth regulatory factor

Country Status (29)

Country Link
JP (1) JP2559035B2 (de)
KR (1) KR920005920B1 (de)
CN (1) CN1017626B (de)
AT (1) AT400444B (de)
AU (2) AU601168B2 (de)
BE (1) BE905957A (de)
CA (1) CA1340296C (de)
CH (1) CH675727A5 (de)
CY (1) CY1608A (de)
DE (2) DE3645095C2 (de)
DK (1) DK174094B1 (de)
ES (1) ES2003180A6 (de)
FI (1) FI91484C (de)
FR (1) FR2597108B1 (de)
GB (1) GB2185485B (de)
GR (1) GR862936B (de)
HK (1) HK65691A (de)
HU (1) HU210694B (de)
IE (1) IE59415B1 (de)
IL (1) IL81017A (de)
IT (1) IT1213428B (de)
LU (1) LU86718A1 (de)
NL (1) NL8603209A (de)
NO (1) NO174556C (de)
NZ (1) NZ218634A (de)
OA (1) OA08494A (de)
PT (1) PT83986B (de)
SE (1) SE505059C2 (de)
SG (1) SG60891G (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645828A (en) * 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
NZ218634A (en) * 1985-12-20 1991-06-25 Oncogen Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits
US5681930A (en) * 1985-12-20 1997-10-28 Bristol-Myers Squibb Company Anti-oncostatin M monoclonal antibodies
NZ226799A (en) * 1987-11-06 1991-08-27 Oncogen Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor
IL97622A (en) * 1990-03-29 1997-06-10 Oncogen Limited Partnership Se Monoclonal antibodies that inhibit growth of kaposi's sarcoma
IL97623A (en) * 1990-03-29 1996-01-19 Bristol Myers Squibb Co Monoclonal antibodies against oncostatin M, their preparation and pharmaceutical preparations containing them
WO1992002556A1 (en) * 1990-08-02 1992-02-20 Michael Valentine Agrez Human colon cancer cell-derived fibroblast elongation factor
CZ195193A3 (en) * 1992-09-25 1994-04-13 Lilly Co Eli Modified factor-4 of blood platelets, process of its preparation and pharmaceutical preparation in which it is comprised

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132776A (en) * 1978-02-15 1979-01-02 University Patents, Inc. Delivery of immunologically active components of transfer factor
US4645828A (en) * 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
NZ218634A (en) * 1985-12-20 1991-06-25 Oncogen Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits

Also Published As

Publication number Publication date
FR2597108A1 (fr) 1987-10-16
FR2597108B1 (fr) 1991-02-15
CH675727A5 (de) 1990-10-31
GR862936B (en) 1987-10-28
AT400444B (de) 1995-12-27
DE3645095C2 (de) 1993-11-18
DE3643428A1 (de) 1987-09-24
SE8605459L (sv) 1987-06-21
IL81017A0 (en) 1987-03-31
CN1017626B (zh) 1992-07-29
DK174094B1 (da) 2002-06-10
FI865156A (fi) 1987-06-21
FI865156A0 (fi) 1986-12-17
DK615386A (da) 1987-06-21
NL8603209A (nl) 1987-07-16
AU639048B2 (en) 1993-07-15
HU210694B (en) 1995-06-28
NZ218634A (en) 1991-06-25
GB8629997D0 (en) 1987-01-28
ATA340686A (de) 1995-05-15
PT83986A (en) 1987-01-01
CY1608A (en) 1992-04-03
JPS62236498A (ja) 1987-10-16
IL81017A (en) 1993-01-14
DK615386D0 (da) 1986-12-18
SE505059C2 (sv) 1997-06-16
IE863345L (en) 1987-06-20
LU86718A1 (fr) 1988-07-14
GB2185485B (en) 1990-07-04
JP2559035B2 (ja) 1996-11-27
OA08494A (fr) 1988-07-29
FI91484C (fi) 1994-07-11
BE905957A (fr) 1987-06-17
SG60891G (en) 1991-08-23
KR870005645A (ko) 1987-07-06
NO174556B (no) 1994-02-14
SE8605459D0 (sv) 1986-12-18
IT8622787A0 (it) 1986-12-19
IT1213428B (it) 1989-12-20
PT83986B (pt) 1989-07-31
HK65691A (en) 1991-08-23
NO174556C (no) 1994-05-25
KR920005920B1 (ko) 1992-07-24
NO865178L (no) 1987-06-22
AU601168B2 (en) 1990-09-06
FI91484B (fi) 1994-03-31
IE59415B1 (en) 1994-02-23
AU6660886A (en) 1987-06-25
AU6776590A (en) 1991-03-14
CN86108955A (zh) 1987-12-02
ES2003180A6 (es) 1988-10-16
HUT43103A (en) 1987-09-28
GB2185485A (en) 1987-07-22
NO865178D0 (no) 1986-12-19
DE3643428C2 (de) 1990-08-23

Similar Documents

Publication Publication Date Title
EP0326120B1 (de) Menschliches IFN-beta2/IL-6, dessen Reinigung und Verwendungen
US6419918B1 (en) Human pluripotent hematopoietic colony stimulating factor, method of use
US4863899A (en) Biologically active polypeptides
SE504554C2 (sv) Ett nytt bifunktionellt tillväxtmodulerande glykoprotein
JP2002155100A (ja) 幹細胞増殖因子
DK171600B1 (da) Immunosuppressiv faktor og fremgangsmåde til fremstilling af denne faktor
CA1340296C (en) Cell growth regulatory factor
US5428012A (en) Oncostatin M and novel compositions having anti-neoplastic activity
US4613459A (en) Lymphocyte growth factor
EP0290948A2 (de) Oncostatin M und neue Zusammensetzungen mit anti-neoplastischer Aktivität
AU689560B2 (en) Method for stimulating profileration of colon cells using POMC-76-103
US4720482A (en) Pharmaceutical compositions containing one or more lymphocyte growth factors
US5451506A (en) Oncostatin M and novel compositions having anti-neoplastic activity
EP0234545A2 (de) Gereinigter humaner Angiogenfaktor, Verfahren zu seiner Herstellung und pharmazeutische Präparate
FI98373B (fi) Uusi diagnostisesti käyttökelpoinen polypeptidi, onkostatiini M
EP0833656A2 (de) Restrictine p/activine a enthaltende pharmazeutische zusammensetzungen und ihre verwendung als il-6 oder/und il-11 antagonisten
CA1340266C (en) Human pluripotent hematopoietic colony stimulating factor, method of production and use
US5147798A (en) Monophenotypic xenograft of megakaryocytic lineage and origin
KR960016305B1 (ko) 온코스타틴 m 및 항신생물 활성을 갖는 신규 조성물
NZ231140A (en) Transforming growth factor (tgf) and its isolation

Legal Events

Date Code Title Description
MKEX Expiry

Effective date: 20151229