CA1289878C - Composition for stimulating chondrocytes and osteoblasts (osseinhydroxyapatite compound), method for its production and pharmaceutical products containing said composition - Google Patents

Composition for stimulating chondrocytes and osteoblasts (osseinhydroxyapatite compound), method for its production and pharmaceutical products containing said composition

Info

Publication number
CA1289878C
CA1289878C CA000534786A CA534786A CA1289878C CA 1289878 C CA1289878 C CA 1289878C CA 000534786 A CA000534786 A CA 000534786A CA 534786 A CA534786 A CA 534786A CA 1289878 C CA1289878 C CA 1289878C
Authority
CA
Canada
Prior art keywords
ohc
bone
maximum
chondrocytes
dehydrated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000534786A
Other languages
English (en)
French (fr)
Inventor
Thea Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robapharm AG
Original Assignee
Robapharm AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robapharm AG filed Critical Robapharm AG
Application granted granted Critical
Publication of CA1289878C publication Critical patent/CA1289878C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/84Bones; tendons; teeth; cartilage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
CA000534786A 1986-08-05 1987-04-15 Composition for stimulating chondrocytes and osteoblasts (osseinhydroxyapatite compound), method for its production and pharmaceutical products containing said composition Expired - Lifetime CA1289878C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3626414A DE3626414C2 (de) 1986-08-05 1986-08-05 Präparat zur Stimulierung von Chondrocyten und Osteoblasten (Ossein-Hydroxyapatit-Komplex), Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel
DEP3626414.8 1986-08-05

Publications (1)

Publication Number Publication Date
CA1289878C true CA1289878C (en) 1991-10-01

Family

ID=6306689

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000534786A Expired - Lifetime CA1289878C (en) 1986-08-05 1987-04-15 Composition for stimulating chondrocytes and osteoblasts (osseinhydroxyapatite compound), method for its production and pharmaceutical products containing said composition

Country Status (20)

Country Link
US (1) US4919931A (US08158827-20120417-C00028.png)
EP (1) EP0255565B1 (US08158827-20120417-C00028.png)
JP (1) JPS6344527A (US08158827-20120417-C00028.png)
KR (2) KR880002897A (US08158827-20120417-C00028.png)
CN (1) CN1028237C (US08158827-20120417-C00028.png)
AR (1) AR242589A1 (US08158827-20120417-C00028.png)
AT (1) ATE77239T1 (US08158827-20120417-C00028.png)
AU (1) AU604014B2 (US08158827-20120417-C00028.png)
CA (1) CA1289878C (US08158827-20120417-C00028.png)
DE (2) DE3626414C2 (US08158827-20120417-C00028.png)
DK (1) DK175488B1 (US08158827-20120417-C00028.png)
ES (1) ES2041647T3 (US08158827-20120417-C00028.png)
FI (1) FI91877C (US08158827-20120417-C00028.png)
GR (1) GR3005579T3 (US08158827-20120417-C00028.png)
HU (1) HU205373B (US08158827-20120417-C00028.png)
IE (1) IE59916B1 (US08158827-20120417-C00028.png)
IL (1) IL82213A (US08158827-20120417-C00028.png)
NO (1) NO173786C (US08158827-20120417-C00028.png)
PT (1) PT84693B (US08158827-20120417-C00028.png)
ZA (1) ZA872701B (US08158827-20120417-C00028.png)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861590A (en) * 1986-09-25 1989-08-29 Colgate-Palmolive Company Sustained release fluoride and calcium composition
US4859467A (en) * 1986-09-25 1989-08-22 Colgate-Palmotive Company Sustained release fluoride composition
JPH02149618A (ja) * 1988-11-30 1990-06-08 Kobe Steel Ltd 加工性に優れた高強度熱延鋼板の製造方法
CN1045719C (zh) * 1993-04-10 1999-10-20 北京市西城区华新生化技术研究所 口服接骨和治骨质疏松液
EP0635518B1 (en) * 1993-07-23 2003-10-08 Kato, Yukio, Prof. New chondrocyte protein
EP0777491B1 (de) * 1994-08-23 2004-11-17 Deutsche Gelatine-Fabriken Stoess AG Verwendung von geschmacksneutralem, hydrolysiertem kollagen und mittel enthaltend dasselbe
US5788941A (en) * 1996-01-31 1998-08-04 Steris Corporation Method of sterilization of bone tussue
JPH09238291A (ja) * 1996-02-29 1997-09-09 Sony Corp メニュー操作方法及び電子機器及びテレビジョン受像機
NL1020729C2 (nl) * 2002-05-31 2003-12-02 Gelatine Smits Beheer B V Calciumbevattende samenstelling, werkwijze voor het bereiden daarvan, en farmaceutisch preparaat op basis van de samenstelling.
CN1212126C (zh) * 2002-07-09 2005-07-27 中国科学院长春应用化学研究所 纳米羟基磷灰石补钙剂
JP4369969B2 (ja) * 2007-10-26 2009-11-25 株式会社アールビーエス 生体適合性材料並びにその製造方法
DK2699249T3 (en) 2011-04-19 2017-01-09 Bioiberica cartilage Product
RU2478394C1 (ru) * 2011-11-23 2013-04-10 Федеральное государственное бюджетное учреждение "Российский научный центр "Восстановительная травматология и ортопедия" имени академика Г.А. Илизарова" Министерства здравоохранения и социального развития Российской Федерации Биоматериал для возмещения дефектов костей и способ его получения
EP3041482B1 (en) * 2013-09-05 2021-06-09 Waitaki Biosciences High osteocalcin microcrystalline hydroxyapatite for calcium supplement

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE894895C (de) * 1950-03-06 1953-10-29 Albert Dr Reissner Verfahren zur Herstellung eines Praeparates zur Anregung der Zahnerhaltung
BE650626A (US08158827-20120417-C00028.png) * 1962-02-28 1900-01-01
USRE28093E (en) * 1962-02-28 1974-07-30 Wound-healing cartilage powder
US3400199A (en) * 1965-02-26 1968-09-03 Leslie L. Balassa Wound-healing cartilage powder
DE2425266A1 (de) * 1974-05-24 1975-11-27 Lothar Tischmann Zum einnehmen bestimmtes naehr- und heilmittel aus tierischer knochen-substanz und verfahren zu seiner herstellung
DE2840064C2 (de) * 1978-09-14 1989-09-21 Hans Dr.med. Dr.med.dent. 8000 München Scheicher Verfahren zur Herstellung von Knochenkontaktschichten
US4232425A (en) * 1980-01-15 1980-11-11 Darling & Company Method of producing stabilized bone
US4455256A (en) * 1981-05-05 1984-06-19 The Regents Of The University Of California Bone morphogenetic protein
US4294753A (en) * 1980-08-04 1981-10-13 The Regents Of The University Of California Bone morphogenetic protein process
ZA816771B (en) * 1980-10-07 1982-10-27 Lensfield Prod Ltd Protein production
US4444752A (en) * 1982-09-13 1984-04-24 Lescarden Ltd. Method for treating progressive systemic sclerosis
US4436720A (en) * 1983-03-04 1984-03-13 Pakhomov Gennady N Granulated treatment-and-prophylactic dental preparation possessing anticarious effect
NZ210699A (en) * 1984-01-04 1989-06-28 Int Genetic Eng Isolation of an osteogenic protein of the p3 immunologically related family
DE3409372A1 (de) * 1984-03-14 1985-09-19 Dr. Ruhland Nachf. GmbH, 8425 Neustadt Material zum vitalisieren von implantatoberflaechen
DE3422466C1 (de) * 1984-06-16 1986-03-20 Lothar 6750 Kaiserslautern Tischmann Verfahren zum Herstellen eines eßbaren, proteinhaltigen Knochenmehlpräparates aus frischen Tierknochen
US4620327A (en) * 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction

Also Published As

Publication number Publication date
AR242589A1 (es) 1993-04-30
AU604014B2 (en) 1990-12-06
AU7157787A (en) 1988-02-11
GR3005579T3 (US08158827-20120417-C00028.png) 1993-06-07
ATE77239T1 (de) 1992-07-15
DE3626414C2 (de) 1994-11-10
FI91877C (fi) 1994-08-25
NO871599L (no) 1988-02-08
HUT44047A (en) 1988-01-28
JPS6344527A (ja) 1988-02-25
IL82213A0 (en) 1987-10-30
EP0255565B1 (en) 1992-06-17
FI871670A0 (fi) 1987-04-15
PT84693B (pt) 1990-06-29
PT84693A (en) 1987-05-01
NO173786B (no) 1993-10-25
DK175488B1 (da) 2004-11-08
DK196387D0 (da) 1987-04-15
KR880002897A (ko) 1988-05-12
IL82213A (en) 1991-08-16
FI871670A (fi) 1988-02-06
NO173786C (no) 1994-02-02
US4919931A (en) 1990-04-24
CN1028237C (zh) 1995-04-19
HU205373B (en) 1992-04-28
DE3626414A1 (de) 1988-02-11
EP0255565A3 (en) 1990-01-31
IE870983L (en) 1988-02-05
JPH0558606B2 (US08158827-20120417-C00028.png) 1993-08-27
DE3779829T2 (de) 1993-01-14
ZA872701B (en) 1987-11-25
EP0255565A2 (en) 1988-02-10
NO871599D0 (no) 1987-04-15
ES2041647T3 (es) 1993-12-01
FI91877B (fi) 1994-05-13
DK196387A (da) 1988-02-06
KR880002534A (ko) 1988-05-09
DE3779829D1 (de) 1992-07-23
IE59916B1 (en) 1994-04-20
KR960009651B1 (en) 1996-07-23
CN87102744A (zh) 1988-02-17

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