CA1251399A - Method for purification of influenza virus - Google Patents

Method for purification of influenza virus

Info

Publication number
CA1251399A
CA1251399A CA000488281A CA488281A CA1251399A CA 1251399 A CA1251399 A CA 1251399A CA 000488281 A CA000488281 A CA 000488281A CA 488281 A CA488281 A CA 488281A CA 1251399 A CA1251399 A CA 1251399A
Authority
CA
Canada
Prior art keywords
sulfuric acid
influenza virus
acid ester
cellulose
crosslinked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000488281A
Other languages
English (en)
French (fr)
Inventor
Tetsuya Oka
Tetsuo Kawahara
Kunio Ohkuma
Mitsuo Sakoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Application granted granted Critical
Publication of CA1251399A publication Critical patent/CA1251399A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA000488281A 1984-08-09 1985-08-08 Method for purification of influenza virus Expired CA1251399A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59167324A JPS6147186A (ja) 1984-08-09 1984-08-09 インフルエンザウイルスの精製方法
JP167324/1984 1984-08-09

Publications (1)

Publication Number Publication Date
CA1251399A true CA1251399A (en) 1989-03-21

Family

ID=15847633

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000488281A Expired CA1251399A (en) 1984-08-09 1985-08-08 Method for purification of influenza virus

Country Status (7)

Country Link
US (1) US4724210A (enExample)
EP (1) EP0171086B1 (enExample)
JP (1) JPS6147186A (enExample)
KR (1) KR920009733B1 (enExample)
AT (1) ATE54468T1 (enExample)
CA (1) CA1251399A (enExample)
DE (1) DE3578613D1 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
US5215739A (en) * 1989-04-05 1993-06-01 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
FR2667622B1 (fr) * 1990-10-08 1994-10-07 Kaysersberg Sa Montisse lie hydrauliquement et son procede de fabrication.
IT1248075B (it) * 1991-06-18 1995-01-05 Sclavo Spa Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono.
US5447859A (en) * 1993-07-16 1995-09-05 Viagene Method for the purification or removal of retroviruses using sulfated cellulose
EP1010981A1 (de) * 1998-12-18 2000-06-21 Diagor GmbH Konjugate zum Nachweis von Viren und deren Verwendung
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
PL354822A1 (en) * 2002-06-30 2004-01-12 Instytut Immunologii i Terapii Doświadczalnej PANwe Wrocławiu Method of receiving purified bacteriophage preparations and new applications of polysaccharide or its esterificated derivative
JP2007523621A (ja) * 2003-06-18 2007-08-23 オニックス ファーマシューティカルズ,インコーポレイティド ウイルスを精製するための方法
ATE478137T1 (de) * 2003-06-20 2010-09-15 Microbix Biosystems Inc Verbesserungen bei der virusproduktion
CN1902312B (zh) 2003-11-04 2011-02-23 株式会社载体研究所 制备导入了基因的树突细胞的方法
JP4969444B2 (ja) 2005-06-14 2012-07-04 ディナベック株式会社 抗体の作製方法
US8877187B2 (en) * 2005-07-25 2014-11-04 Avianax, Llc Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases
CA2616561C (en) * 2005-07-25 2018-12-18 Avianax, Llc Therapeutic goose antibodies for treatment and prophylaxis of transmittable viral diseases
EP1808697A1 (en) * 2006-01-13 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Use of an ion exchange matrix for determining the concentration of virus particles and/or virus antigens
EP1983048A4 (en) 2006-01-17 2009-04-22 Dnavec Corp NEW PROTEIN EXPRESSION SYSTEM
US20100297604A1 (en) * 2006-06-09 2010-11-25 Xing-Xiang Li Methods and reagents for virus isolation and detection
EP1878791A1 (en) * 2006-07-11 2008-01-16 Bia Separations D.O.O. Method for influenza virus purification
EP2048232A4 (en) 2006-07-13 2010-10-13 Dnavec Corp NON-REPLICATIVE PARAMYXOVIRIDAE VIRUS VECTOR
EP2066418A4 (en) * 2006-09-29 2011-12-28 Ge Healthcare Bio Sciences Ab SEPARATION MATRIX FOR VIRAL PURIFICATION
EP1982727A1 (en) * 2007-04-17 2008-10-22 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for purification of viral proteins
US20100203027A1 (en) 2007-04-27 2010-08-12 Kyushu Univeristy National University Viral vector for gene therapy
WO2009006420A2 (en) * 2007-06-29 2009-01-08 Avianax, Llc Vaccine production for pathogenic bird viral diseases
JP5389342B2 (ja) * 2007-08-09 2014-01-15 デンカ生研株式会社 吸着担体及び吸着担体の製造方法
JP5716297B2 (ja) 2009-06-25 2015-05-13 Jnc株式会社 クロマトグラフィー用充填剤、その製造方法、およびそれを用いたウイルス用ワクチンの製造方法
JP2013523175A (ja) 2010-04-14 2013-06-17 イーエムディー・ミリポア・コーポレーション 高力価、高純度のウイルスストックの作製方法及びその使用方法
IN2015DN02055A (enExample) 2012-09-17 2015-08-14 Grace W R & Co
CN105518059B (zh) 2013-09-02 2019-01-01 捷恩智株式会社 多孔性纤维素粒子的制造方法、多孔性纤维素粒子及色谱法用填充剂
DE102013017014B4 (de) 2013-10-14 2017-03-30 Sartorius Stedim Biotech Gmbh Sulfatierte Cellulosehydrat-Membran, Verfahren zur ihrer Herstellung und Verwendung der Membran als Adsorptionsmembran für die Virenaufreinigung
EP3137209B1 (en) 2014-05-02 2022-10-05 W.R. Grace & CO. - CONN. Functionalized support material and methods of making and using functionalized support material
EP2966093A1 (en) * 2014-07-07 2016-01-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process for the preparation of magnetic sulfated cellulose particles, magnetic sulfated cellulose particles and their use
SG10201911134QA (en) 2015-06-05 2020-01-30 Grace W R & Co Adsorbent bioprocessing clarification agents and methods of making and using the same
US10626376B2 (en) 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt
CN106622159B (zh) * 2016-12-22 2019-06-14 苏州楚博生物技术有限公司 用于蛋白药物纯化的亲和层析介质

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131092C (enExample) *
US3105012A (en) * 1961-10-19 1963-09-24 Parke Davis & Co Antigen products and means for producing the same
BE662899A (enExample) * 1964-04-22
US3547779A (en) * 1968-12-18 1970-12-15 Merck & Co Inc Process for producing purified concentrated influenza virus
SE356735B (enExample) * 1970-12-02 1973-06-04 Svenska Cellulosa Ab
US3842062A (en) * 1972-09-27 1974-10-15 Du Pont Water-soluble complexes of protein and anionic polyelectrolytes such as sodium carboxymethyl cellulose
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US4160019A (en) * 1973-06-25 1979-07-03 Bjorklund Knut B Detection of cancer associated polypeptide antigen and preparation of antibodies thereto
IL49752A (en) * 1975-07-09 1979-07-25 Kabi Ab Compositions having affinity for hepatitis virus and method for hepatitis virus removal or concentration
SE420977B (sv) * 1976-03-18 1981-11-16 Kabi Ab Forfarande for rening och isolering av hepatitvirus for vaccinframstellning
US4181713A (en) * 1978-10-30 1980-01-01 Merck & Co., Inc. Isolation of HBs Ag
DE3014189A1 (de) * 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
JPS57136528A (en) * 1981-02-09 1982-08-23 Hayashibara Biochem Lab Inc Preparation of viral vaccine
US4434093A (en) * 1982-07-26 1984-02-28 Ortho Diagnostic Systems Inc. Methods for preparation of HBs Ag free gamma globulins
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen

Also Published As

Publication number Publication date
KR870001835A (ko) 1987-03-28
DE3578613D1 (de) 1990-08-16
KR920009733B1 (ko) 1992-10-22
EP0171086B1 (en) 1990-07-11
ATE54468T1 (de) 1990-07-15
US4724210A (en) 1988-02-09
EP0171086A2 (en) 1986-02-12
JPS6147186A (ja) 1986-03-07
EP0171086A3 (en) 1988-01-13
JPS6230752B2 (enExample) 1987-07-03

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