CA1246583A - 4-(isoxazolyl)-thiazole-2- oxamic acids and derivatives thereof - Google Patents

4-(isoxazolyl)-thiazole-2- oxamic acids and derivatives thereof

Info

Publication number
CA1246583A
CA1246583A CA000487853A CA487853A CA1246583A CA 1246583 A CA1246583 A CA 1246583A CA 000487853 A CA000487853 A CA 000487853A CA 487853 A CA487853 A CA 487853A CA 1246583 A CA1246583 A CA 1246583A
Authority
CA
Canada
Prior art keywords
group
alkoxy
optionally substituted
phenyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000487853A
Other languages
English (en)
French (fr)
Other versions
CA1261847C (enExample
Inventor
Angelo Carenzi
Dario Chiarino
Bella Davide Della
Giancarlo Grancini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Priority to CA000576255A priority Critical patent/CA1261847A/en
Application granted granted Critical
Publication of CA1246583A publication Critical patent/CA1246583A/en
Publication of CA1261847C publication Critical patent/CA1261847C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA000487853A 1984-07-31 1985-07-31 4-(isoxazolyl)-thiazole-2- oxamic acids and derivatives thereof Expired CA1246583A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000576255A CA1261847A (en) 1984-07-31 1988-08-31 Process for preparing intermediates for preparing 4- (isozaxolyl)-thiazole-2-oxamic acids and derivatives thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22150/84A IT1183061B (it) 1984-07-31 1984-07-31 Composti dotati di attivita'antiallergica

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000576255A Division CA1261847A (en) 1984-07-31 1988-08-31 Process for preparing intermediates for preparing 4- (isozaxolyl)-thiazole-2-oxamic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
CA1246583A true CA1246583A (en) 1988-12-13
CA1261847C CA1261847C (enExample) 1989-09-26

Family

ID=11192238

Family Applications (2)

Application Number Title Priority Date Filing Date
CA000487853A Expired CA1246583A (en) 1984-07-31 1985-07-31 4-(isoxazolyl)-thiazole-2- oxamic acids and derivatives thereof
CA000487852A Expired CA1243318A (en) 1984-07-31 1985-07-31 Process for preparing 4-(isoxazolyl)-thiazole-2- oxamic acid derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA000487852A Expired CA1243318A (en) 1984-07-31 1985-07-31 Process for preparing 4-(isoxazolyl)-thiazole-2- oxamic acid derivatives

Country Status (13)

Country Link
US (2) US4766138A (enExample)
EP (2) EP0190298B1 (enExample)
JP (2) JPS61502896A (enExample)
AU (2) AU583847B2 (enExample)
CA (2) CA1246583A (enExample)
DE (2) DE3573781D1 (enExample)
DK (2) DK164364C (enExample)
ES (4) ES8608516A1 (enExample)
FI (2) FI85473C (enExample)
IL (1) IL75981A (enExample)
IT (1) IT1183061B (enExample)
WO (2) WO1986000899A1 (enExample)
ZA (1) ZA855743B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1183061B (it) * 1984-07-31 1987-10-05 Zambon Spa Composti dotati di attivita'antiallergica
IT1204960B (it) * 1987-03-25 1989-03-10 Zambon Farmaceutici Spa Composti dotati di attivita' antiallergica
US4946963A (en) * 1987-11-13 1990-08-07 The University Of North Carolina At Chapel Hill Compounds for the control of hyperlipidemia using N-substituted isoxazolidine-3,5-diones
DE3844227A1 (de) * 1988-12-29 1990-07-05 Basf Ag 3(2h)-pyridazinonderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
DE19625622A1 (de) * 1996-06-26 1998-01-02 Siemens Ag Lichtabstrahlendes Halbleiterbauelement mit Lumineszenzkonversionselement
KR100662956B1 (ko) 1996-06-26 2006-12-28 오스람 게젤샤프트 미트 베쉬랭크터 하프퉁 발광 변환 소자를 포함하는 발광 반도체 소자
DE19638667C2 (de) 1996-09-20 2001-05-17 Osram Opto Semiconductors Gmbh Mischfarbiges Licht abstrahlendes Halbleiterbauelement mit Lumineszenzkonversionselement
ES2629414T3 (es) * 2003-12-26 2017-08-09 Kyowa Hakko Kirin Co., Ltd. Derivados de tiazol
US7935706B2 (en) 2006-02-23 2011-05-03 Shionogi & Co., Ltd. Nitrogen-containing heterocycle derivatives substituted with cyclic group

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2429210A1 (fr) * 1978-06-19 1980-01-18 Fabre Sa Pierre Derives de phenyl-4 thiazolyl-2 oxamates utiles dans le traitement de l'asthme
DE3027527A1 (de) * 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
FR2494272A1 (fr) * 1980-11-19 1982-05-21 Fabre Sa Pierre Derives de l'acide thiazolyl-2 oxamique substitues en position 4 par un radical thienyle ou furyle, leur preparation et leur utilisation comme medicaments
IT1183061B (it) * 1984-07-31 1987-10-05 Zambon Spa Composti dotati di attivita'antiallergica

Also Published As

Publication number Publication date
IT8422150A1 (it) 1986-01-31
EP0191045A1 (en) 1986-08-20
DK142086D0 (da) 1986-03-26
ES8703459A1 (es) 1987-02-16
FI861330L (fi) 1986-03-26
ES546419A0 (es) 1987-02-16
CA1243318A (en) 1988-10-18
EP0190298B1 (en) 1989-10-18
US4766137A (en) 1988-08-23
DK141986A (da) 1986-05-28
JPH0574592B2 (enExample) 1993-10-18
WO1986000900A1 (en) 1986-02-13
ZA855743B (en) 1986-05-28
FI85473B (fi) 1992-01-15
ES552514A0 (es) 1987-05-01
DK141986D0 (da) 1986-03-26
CA1261847C (enExample) 1989-09-26
EP0191045B1 (en) 1989-12-20
ES552513A0 (es) 1987-10-16
AU4724885A (en) 1986-02-25
AU4671785A (en) 1986-02-25
IT8422150A0 (it) 1984-07-31
AU583847B2 (en) 1989-05-11
IL75981A0 (en) 1985-12-31
DE3574874D1 (de) 1990-01-25
FI861330A0 (fi) 1986-03-26
DE3573781D1 (en) 1989-11-23
DK142086A (da) 1986-05-29
ES8800217A1 (es) 1987-10-16
WO1986000899A1 (en) 1986-02-13
US4766138A (en) 1988-08-23
JPS61502896A (ja) 1986-12-11
FI83650B (fi) 1991-04-30
FI83650C (fi) 1991-08-12
ES8705434A1 (es) 1987-05-01
IL75981A (en) 1989-07-31
FI861329A0 (fi) 1986-03-26
JPH0576946B2 (enExample) 1993-10-25
DK164364C (da) 1992-11-02
ES8608516A1 (es) 1986-07-16
FI861329L (fi) 1986-03-26
AU584118B2 (en) 1989-05-18
JPS61502959A (ja) 1986-12-18
ES546420A0 (es) 1986-07-16
IT1183061B (it) 1987-10-05
EP0190298A1 (en) 1986-08-13
DK164364B (da) 1992-06-15
FI85473C (fi) 1992-04-27

Similar Documents

Publication Publication Date Title
ATE102193T1 (de) Thiazolidinedionederivate.
NZ218786A (en) 1,4 disubstituted piperidine derivatives and pharmaceutical compositions
DE10199003I1 (de) Substituierte Thiazolidinionderivate
HUT61742A (en) Process for producing cyclic amide derivatives and pharmaceutical compositions comprising same
HUT59394A (en) Process for producing piperazine derivatives and pharmaceutical compositions comprising same
CA1246583A (en) 4-(isoxazolyl)-thiazole-2- oxamic acids and derivatives thereof
ATE138571T1 (de) Verwendung von dioxabicyclo (3.3.0>octane derivaten zur herstellung eines arzneimittels zur hemmung des cholesterinmetabolismus.
ATE75737T1 (de) Indenothiazolderivate und verfahren zu ihrer herstellung.
DK0492178T3 (da) Naphthoesyre-derivat
FI911016A0 (fi) Menetelmä farmakologisesti aktiivisten substituoitujen -diketonien valmistamiseksi
DE69017779D1 (de) Hydroxylamin-derivate.
ES373231A1 (es) Perfeccionamientos en la fotopolimerizacion de compuestos insaturados.
ATE113958T1 (de) Organische ester der alkoholischen derivate der 19-nor-steroide und die salze davon, verfahren zu deren herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und pharmazeutische präparate davon.
ES8702421A1 (es) Procedimiento para preparar nuevos pirimido (2,1-b) benzo- tiazoles
ATE125256T1 (de) Zwischenprodukte der mureidomycin-gruppe, ihre herstellung und verwendung.
GB1489849A (en) 4,4'-bi-piperidylidene derivatives and their use as polymer stabilizers
DE3876546D1 (de) Ethanon-oxime.
DE69301639D1 (de) Tetrahydronaphtalenderivate, ihre Herstellung und ihre therapeutische Verwendung
ES422737A1 (es) Procedimiento para la obtencion de compuestos heterocicli- cos a base de piperazina u homopiperazina.
JPS5594382A (en) Chroman-based compound and cholestrol lowering drug comprising it
ATE148099T1 (de) Tri(c1-c6 alkoxy)benzolderivat
ATE98635T1 (de) Sterisch gehinderte aminoverbindungen und verfahren zu deren herstellung.
DE3863041D1 (de) 1,3,5-nonatrienderivate, deren herstellung und verwendung.
ATE1585T1 (de) Clavulansaeurederivate, ihre herstellung und sie enthaltende pharmazeutische praeparate.

Legal Events

Date Code Title Description
MKEX Expiry