CA1167440A - 1,4,9,10-tetrahydro-pyrazolo[4,3-e]pyrido[3,2- b][1,4]diazepin-10-ones, processes for their preparation and pharmaceutical compositions containing them - Google Patents
1,4,9,10-tetrahydro-pyrazolo[4,3-e]pyrido[3,2- b][1,4]diazepin-10-ones, processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- CA1167440A CA1167440A CA000404541A CA404541A CA1167440A CA 1167440 A CA1167440 A CA 1167440A CA 000404541 A CA000404541 A CA 000404541A CA 404541 A CA404541 A CA 404541A CA 1167440 A CA1167440 A CA 1167440A
- Authority
- CA
- Canada
- Prior art keywords
- compound
- pyrazolo
- tetrahydro
- pyrido
- diazepin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813122670 DE3122670A1 (de) | 1981-06-06 | 1981-06-06 | "neue 1,4,9,10-tetrahydro-pyrazolo(4,3-e) pyrido(3,2-b)(1,4)diazepin-10-one, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen" |
DEP3122670.1 | 1981-06-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1167440A true CA1167440A (en) | 1984-05-15 |
Family
ID=6134176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000404541A Expired CA1167440A (en) | 1981-06-06 | 1982-06-04 | 1,4,9,10-tetrahydro-pyrazolo[4,3-e]pyrido[3,2- b][1,4]diazepin-10-ones, processes for their preparation and pharmaceutical compositions containing them |
Country Status (27)
Country | Link |
---|---|
US (1) | US4381303A (de) |
EP (1) | EP0066774B1 (de) |
JP (1) | JPS57212182A (de) |
KR (1) | KR880001719B1 (de) |
AR (1) | AR229124A1 (de) |
AT (1) | ATE10744T1 (de) |
AU (1) | AU552765B2 (de) |
CA (1) | CA1167440A (de) |
CS (1) | CS226743B2 (de) |
DD (1) | DD202574A5 (de) |
DE (2) | DE3122670A1 (de) |
DK (1) | DK253382A (de) |
ES (1) | ES512846A0 (de) |
FI (1) | FI71560C (de) |
GB (1) | GB2117755B (de) |
GR (1) | GR76438B (de) |
HU (1) | HU186067B (de) |
IE (1) | IE53067B1 (de) |
IL (1) | IL65977A (de) |
NO (1) | NO158063C (de) |
NZ (1) | NZ200859A (de) |
PH (1) | PH17719A (de) |
PL (1) | PL135845B1 (de) |
PT (1) | PT75016B (de) |
SU (1) | SU1103795A3 (de) |
YU (1) | YU118282A (de) |
ZA (1) | ZA823919B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3643666A1 (de) * | 1986-12-20 | 1988-06-30 | Thomae Gmbh Dr K | Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US4749788A (en) * | 1987-04-13 | 1988-06-07 | A. H. Robins Company, Incorporated | Process for the preparation of aryl-pyrido(1,4) benzodiazepines |
US5366972A (en) * | 1989-04-20 | 1994-11-22 | Boehringer Ingelheim Pharmaceuticals, Inc. | 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection |
DK0410148T3 (da) * | 1989-06-28 | 1994-08-08 | Boehringer Ingelheim Pharma | Hidtil ukendte 5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)-(1,4)diazepin-6-oner og -thioner og deres anvendelse til forebyggelse eller behandling af AIDS |
CA2052946A1 (en) * | 1990-10-19 | 1992-04-20 | Karl G. Grozinger | Method for the preparation of 5,11-dihydro-6h-dipyrido ¬3,2-b:2', 3'-e| ¬1,4|diazepines |
ES2137113B1 (es) | 1997-07-29 | 2000-09-16 | Almirall Prodesfarma Sa | Nuevos derivados de triazolo-piridazinas heterociclicos. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3450694A (en) * | 1966-02-23 | 1969-06-17 | Abbott Lab | Substituted benzoxazepines and benzothiazepines |
DE2707269A1 (de) * | 1977-02-19 | 1978-08-24 | Hoechst Ag | Heterocyclische stickstoffverbindungen und verfahren zu ihrer herstellung |
CA1154762A (en) * | 1979-08-03 | 1983-10-04 | Georg Rainer | Substituted tetraazatricyclic compounds, a process for their preparation, their use and medicaments containing them |
-
1981
- 1981-06-06 DE DE19813122670 patent/DE3122670A1/de not_active Withdrawn
-
1982
- 1982-05-13 US US06/377,911 patent/US4381303A/en not_active Expired - Fee Related
- 1982-05-25 DE DE8282104549T patent/DE3261530D1/de not_active Expired
- 1982-05-25 AT AT82104549T patent/ATE10744T1/de not_active IP Right Cessation
- 1982-05-25 SU SU823441915A patent/SU1103795A3/ru active
- 1982-05-25 EP EP82104549A patent/EP0066774B1/de not_active Expired
- 1982-06-01 AR AR289564A patent/AR229124A1/es active
- 1982-06-02 GR GR68322A patent/GR76438B/el unknown
- 1982-06-03 KR KR8202494A patent/KR880001719B1/ko active
- 1982-06-03 CS CS824137A patent/CS226743B2/cs unknown
- 1982-06-03 PL PL1982236742A patent/PL135845B1/pl unknown
- 1982-06-03 DD DD82240437A patent/DD202574A5/de unknown
- 1982-06-03 YU YU01182/82A patent/YU118282A/xx unknown
- 1982-06-04 NZ NZ200859A patent/NZ200859A/en unknown
- 1982-06-04 FI FI821992A patent/FI71560C/fi not_active IP Right Cessation
- 1982-06-04 PT PT75016A patent/PT75016B/de unknown
- 1982-06-04 GB GB08216381A patent/GB2117755B/en not_active Expired
- 1982-06-04 PH PH27402A patent/PH17719A/en unknown
- 1982-06-04 JP JP57096080A patent/JPS57212182A/ja active Pending
- 1982-06-04 ZA ZA823919A patent/ZA823919B/xx unknown
- 1982-06-04 IE IE1350/82A patent/IE53067B1/en unknown
- 1982-06-04 NO NO821882A patent/NO158063C/no unknown
- 1982-06-04 CA CA000404541A patent/CA1167440A/en not_active Expired
- 1982-06-04 HU HU821823A patent/HU186067B/hu unknown
- 1982-06-04 AU AU84605/82A patent/AU552765B2/en not_active Ceased
- 1982-06-04 ES ES512846A patent/ES512846A0/es active Granted
- 1982-06-04 DK DK253382A patent/DK253382A/da not_active Application Discontinuation
- 1982-06-04 IL IL65977A patent/IL65977A/xx unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |