CA1120058A - Phenethanolamines, formulations and potentiation of oncolytic drugs - Google Patents
Phenethanolamines, formulations and potentiation of oncolytic drugsInfo
- Publication number
- CA1120058A CA1120058A CA000330569A CA330569A CA1120058A CA 1120058 A CA1120058 A CA 1120058A CA 000330569 A CA000330569 A CA 000330569A CA 330569 A CA330569 A CA 330569A CA 1120058 A CA1120058 A CA 1120058A
- Authority
- CA
- Canada
- Prior art keywords
- dimethyl
- hydroxyethyl
- phenyl
- propylamine
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92166878A | 1978-07-03 | 1978-07-03 | |
| US921,668 | 1978-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1120058A true CA1120058A (en) | 1982-03-16 |
Family
ID=25445786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000330569A Expired CA1120058A (en) | 1978-07-03 | 1979-06-26 | Phenethanolamines, formulations and potentiation of oncolytic drugs |
Country Status (33)
| Country | Link |
|---|---|
| EP (2) | EP0047536B1 (da) |
| JP (1) | JPS559100A (da) |
| AR (2) | AR222658A1 (da) |
| AT (1) | AT370408B (da) |
| AU (1) | AU521744B2 (da) |
| BE (1) | BE877392A (da) |
| BG (3) | BG40482A3 (da) |
| CA (1) | CA1120058A (da) |
| CH (1) | CH641759A5 (da) |
| CS (2) | CS208660B2 (da) |
| DD (1) | DD144763A5 (da) |
| DK (1) | DK268579A (da) |
| EG (1) | EG14400A (da) |
| ES (2) | ES482153A1 (da) |
| FI (1) | FI67686C (da) |
| FR (1) | FR2430409A1 (da) |
| GB (1) | GB2028800B (da) |
| GR (1) | GR72546B (da) |
| HK (1) | HK44087A (da) |
| HU (1) | HU179170B (da) |
| IE (1) | IE48436B1 (da) |
| IL (1) | IL57670A (da) |
| LU (1) | LU81456A1 (da) |
| MX (1) | MX6160E (da) |
| MY (1) | MY8500596A (da) |
| NZ (1) | NZ190859A (da) |
| PH (1) | PH15650A (da) |
| PL (2) | PL123990B1 (da) |
| PT (1) | PT69840A (da) |
| RO (2) | RO83053B (da) |
| SU (2) | SU965351A3 (da) |
| YU (1) | YU154879A (da) |
| ZA (1) | ZA793295B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0006735B1 (en) * | 1978-06-28 | 1983-06-15 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| NL8105170A (nl) * | 1980-12-10 | 1982-07-01 | Thomae Gmbh Dr K | Nieuwe fenylalkylaminen, werkwijze ter bereiding daarvan en de toepassing daarvan als geneesmiddelen. |
| EP0068669A1 (en) * | 1981-06-20 | 1983-01-05 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
| CA1219865A (en) * | 1982-05-14 | 1987-03-31 | Leo Alig | Aziridine phenethanolamine derivatives |
| CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
| EP0102213A1 (en) * | 1982-08-21 | 1984-03-07 | Beecham Group Plc | Ethanolamine derivatives, pharmaceutical compositions containing them, and processes for preparing them |
| PL144053B1 (en) * | 1983-01-31 | 1988-04-30 | Lilly Co Eli | Method of stimulating growth of domesticated animals,improving effectivness of food utilization ba domesticated animals and improving leanness of domesticated animals and fodder pre-mixture |
| US4849453A (en) * | 1983-01-31 | 1989-07-18 | Eli Lilly And Company | Growth promotion |
| US4569801A (en) * | 1984-10-15 | 1986-02-11 | Eli Lilly And Company | Alkylsulfonamidophenylalkylamines |
| JPS62155213A (ja) * | 1985-12-20 | 1987-07-10 | イ−ライ・リリ−・アンド・カンパニ− | 腫瘍細胞崩壊剤 |
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| US5135955A (en) * | 1988-04-25 | 1992-08-04 | Eli Lilly And Company | Propanamine derivatives |
| US5051423A (en) * | 1988-07-13 | 1991-09-24 | Schering Ag | Derivatized alkanolamines as cardiovascular agents |
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| CN1073983C (zh) * | 1994-10-31 | 2001-10-31 | 中国科学院成都有机化学研究所 | 一种β－拟肾上腺素兴奋剂型饲料添加剂的合成方法 |
| US7547716B2 (en) | 2001-06-08 | 2009-06-16 | Institute Of Medicinal Molecular Design, Inc. | Sulfonamide derivatives |
| TW200740779A (en) | 2005-07-22 | 2007-11-01 | Mitsubishi Pharma Corp | Intermediate compound for synthesizing pharmaceutical agent and production method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6610530A (da) * | 1966-07-27 | 1968-01-29 | ||
| BE757005A (fr) * | 1969-10-02 | 1971-04-02 | Bristol Myers Co | Phenethanolamines substituees et procede pour leur preparation |
| US3801631A (en) * | 1972-02-16 | 1974-04-02 | Mead Johnson & Co | 2'-hydroxy-5'-(1-hydroxy-2-(2-methyl-1-phenyl-2-propylamino)ethyl)meth-anesulfonanilide and its salts |
-
1979
- 1979-06-26 IL IL57670A patent/IL57670A/xx unknown
- 1979-06-26 CA CA000330569A patent/CA1120058A/en not_active Expired
- 1979-06-26 DK DK268579A patent/DK268579A/da not_active Application Discontinuation
- 1979-06-27 PH PH22700A patent/PH15650A/en unknown
- 1979-06-27 EG EG386/79A patent/EG14400A/xx active
- 1979-06-27 NZ NZ190859A patent/NZ190859A/en unknown
- 1979-06-28 AU AU48488/79A patent/AU521744B2/en not_active Ceased
- 1979-06-28 YU YU01548/79A patent/YU154879A/xx unknown
- 1979-06-28 PT PT69840A patent/PT69840A/pt unknown
- 1979-06-29 FR FR7916992A patent/FR2430409A1/fr active Granted
- 1979-06-29 HU HU79EI866A patent/HU179170B/hu unknown
- 1979-07-02 EP EP81109790A patent/EP0047536B1/en not_active Expired
- 1979-07-02 BG BG045920A patent/BG40482A3/xx unknown
- 1979-07-02 RO RO105066A patent/RO83053B/ro unknown
- 1979-07-02 GR GR59488A patent/GR72546B/el unknown
- 1979-07-02 BE BE1/9443A patent/BE877392A/fr not_active IP Right Cessation
- 1979-07-02 CS CS794630A patent/CS208660B2/cs unknown
- 1979-07-02 CS CS794630A patent/CS208661B2/cs unknown
- 1979-07-02 RO RO7998011A patent/RO77731A/ro unknown
- 1979-07-02 BG BG044165A patent/BG40480A3/xx unknown
- 1979-07-02 EP EP79301282A patent/EP0007206B1/en not_active Expired
- 1979-07-02 GB GB7922953A patent/GB2028800B/en not_active Expired
- 1979-07-02 SU SU792786502A patent/SU965351A3/ru active
- 1979-07-02 LU LU81456A patent/LU81456A1/xx unknown
- 1979-07-02 FI FI792080A patent/FI67686C/fi not_active IP Right Cessation
- 1979-07-02 CH CH616479A patent/CH641759A5/fr not_active IP Right Cessation
- 1979-07-02 JP JP8489479A patent/JPS559100A/ja active Granted
- 1979-07-02 BG BG045919A patent/BG40481A3/xx unknown
- 1979-07-02 MX MX798145U patent/MX6160E/es unknown
- 1979-07-03 DD DD79214071A patent/DD144763A5/de unknown
- 1979-07-03 ES ES482153A patent/ES482153A1/es not_active Expired
- 1979-07-03 ZA ZA793295A patent/ZA793295B/xx unknown
- 1979-07-03 PL PL1979222867A patent/PL123990B1/pl unknown
- 1979-07-03 AT AT0463979A patent/AT370408B/de not_active IP Right Cessation
- 1979-07-03 PL PL1979216810A patent/PL119783B1/pl unknown
- 1979-07-03 AR AR277165A patent/AR222658A1/es active
- 1979-08-08 IE IE1231/79A patent/IE48436B1/en unknown
-
1980
- 1980-01-18 ES ES487847A patent/ES487847A0/es active Granted
- 1980-09-12 SU SU802977044A patent/SU931102A3/ru active
- 1980-10-06 AR AR282776A patent/AR222727A1/es active
-
1985
- 1985-12-30 MY MY596/85A patent/MY8500596A/xx unknown
-
1987
- 1987-06-04 HK HK440/87A patent/HK44087A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |