CA1100129A - Cephalosporin compounds - Google Patents

Cephalosporin compounds

Info

Publication number
CA1100129A
CA1100129A CA232,136A CA232136A CA1100129A CA 1100129 A CA1100129 A CA 1100129A CA 232136 A CA232136 A CA 232136A CA 1100129 A CA1100129 A CA 1100129A
Authority
CA
Canada
Prior art keywords
methyl
hydroxy
mixture
oxo
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA232,136A
Other languages
English (en)
French (fr)
Inventor
William H.W. Lunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1100129A publication Critical patent/CA1100129A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA232,136A 1974-08-02 1975-07-24 Cephalosporin compounds Expired CA1100129A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49414874A 1974-08-02 1974-08-02
US494,148 1974-08-02
US58392475A 1975-06-10 1975-06-10
US583,924 1975-06-10

Publications (1)

Publication Number Publication Date
CA1100129A true CA1100129A (en) 1981-04-28

Family

ID=27051316

Family Applications (1)

Application Number Title Priority Date Filing Date
CA232,136A Expired CA1100129A (en) 1974-08-02 1975-07-24 Cephalosporin compounds

Country Status (22)

Country Link
JP (1) JPS6123195B2 (xx)
AR (1) AR210998A1 (xx)
AT (1) AT347580B (xx)
BG (1) BG26395A3 (xx)
CA (1) CA1100129A (xx)
CH (1) CH616683A5 (xx)
CS (1) CS189716B2 (xx)
DD (1) DD121114A5 (xx)
DE (1) DE2534071A1 (xx)
DK (1) DK343275A (xx)
FR (1) FR2280381A1 (xx)
GB (1) GB1521073A (xx)
HU (1) HU174130B (xx)
IE (1) IE41590B1 (xx)
IL (1) IL47802A (xx)
NL (1) NL7509053A (xx)
PH (1) PH16078A (xx)
PL (1) PL95607B1 (xx)
RO (1) RO72980A (xx)
SE (1) SE426830B (xx)
SU (1) SU755200A3 (xx)
YU (1) YU197075A (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348518A (en) 1974-05-05 1982-09-07 Hoffmann-La Roche Inc. Cephalosporins
JPS50141233U (xx) * 1974-05-08 1975-11-20
AT366696B (de) * 1977-03-07 1982-04-26 Lilly Co Eli Verfahren zur herstellung von 3-(thiomethyl)cephalosporinen
NL7805715A (nl) * 1977-06-03 1978-12-05 Hoffmann La Roche Werkwijze voor het bereiden van acylderivaten.
US4200745A (en) * 1977-12-20 1980-04-29 Eli Lilly And Company 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
DK225179A (da) 1978-06-22 1979-12-23 Chugai Pharmaceutical Co Ltd Fremgangsmaade til fremstilling af cephalosporinderivater
FI782683A (fi) * 1978-07-19 1980-01-20 Hoffmann La Roche Kefalosporinestrar och -estrar
FR2474030A1 (fr) * 1980-01-17 1981-07-24 Rhone Poulenc Ind Nouvelles dioxotriazines et leur preparation
NL8100089A (nl) 1980-01-17 1981-08-17 Rhone Poulenc Ind Nieuwe thiolen en de bereiding daarvan.
FR2494278A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de la cephalosporine, leurs preparations et les medicaments qui les contiennent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116436B1 (xx) * 1971-05-31 1976-05-24

Also Published As

Publication number Publication date
BG26395A3 (bg) 1979-03-15
GB1521073A (en) 1978-08-09
SE426830B (sv) 1983-02-14
IE41590L (en) 1976-02-02
DE2534071A1 (de) 1976-02-12
DK343275A (da) 1976-02-03
FR2280381A1 (fr) 1976-02-27
YU197075A (en) 1982-05-31
JPS5139693A (xx) 1976-04-02
IE41590B1 (en) 1980-02-13
AT347580B (de) 1979-01-10
DD121114A5 (xx) 1976-07-12
SU755200A3 (en) 1980-08-07
AR210998A1 (es) 1977-10-14
CS189716B2 (en) 1979-04-30
JPS6123195B2 (xx) 1986-06-04
SE7508570L (sv) 1976-02-03
ATA594075A (de) 1976-11-15
NL7509053A (nl) 1976-02-04
RO72980A (ro) 1981-08-30
PL95607B1 (pl) 1977-10-31
IL47802A0 (en) 1975-10-15
FR2280381B1 (xx) 1979-08-10
HU174130B (hu) 1979-11-28
PH16078A (en) 1983-06-20
IL47802A (en) 1980-05-30
CH616683A5 (en) 1980-04-15

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