CA1092117A - Method for the production of 6,7-dimethoxy-4-amino-2- ¬4-(2-furoyl)-1-piperazinyl| quinazoline having an antihypertensive effect - Google Patents

Method for the production of 6,7-dimethoxy-4-amino-2- ¬4-(2-furoyl)-1-piperazinyl| quinazoline having an antihypertensive effect

Info

Publication number
CA1092117A
CA1092117A CA293,065A CA293065A CA1092117A CA 1092117 A CA1092117 A CA 1092117A CA 293065 A CA293065 A CA 293065A CA 1092117 A CA1092117 A CA 1092117A
Authority
CA
Canada
Prior art keywords
furoyl
dimethoxy
piperazinyl
formula
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA293,065A
Other languages
English (en)
French (fr)
Inventor
Erkki J. Honkanen
Aino K. Pippuri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Application granted granted Critical
Publication of CA1092117A publication Critical patent/CA1092117A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA293,065A 1976-12-15 1977-12-14 Method for the production of 6,7-dimethoxy-4-amino-2- ¬4-(2-furoyl)-1-piperazinyl| quinazoline having an antihypertensive effect Expired CA1092117A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI763613A FI58125C (fi) 1976-12-15 1976-12-15 Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande vekan
FI763613 1976-12-15

Publications (1)

Publication Number Publication Date
CA1092117A true CA1092117A (en) 1980-12-23

Family

ID=8510503

Family Applications (1)

Application Number Title Priority Date Filing Date
CA293,065A Expired CA1092117A (en) 1976-12-15 1977-12-14 Method for the production of 6,7-dimethoxy-4-amino-2- ¬4-(2-furoyl)-1-piperazinyl| quinazoline having an antihypertensive effect

Country Status (17)

Country Link
JP (1) JPS5387377A (de)
AT (1) AT358048B (de)
BE (1) BE861821A (de)
CA (1) CA1092117A (de)
CH (1) CH630625A5 (de)
CS (1) CS195347B2 (de)
DD (1) DD133671A1 (de)
DE (1) DE2755637A1 (de)
DK (1) DK144972C (de)
FI (1) FI58125C (de)
HU (1) HU174047B (de)
NL (1) NL7713702A (de)
NO (1) NO147244C (de)
PL (1) PL106031B1 (de)
SE (1) SE435284B (de)
SU (1) SU753360A3 (de)
ZA (1) ZA777223B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
NZ703124A (en) * 2012-05-23 2016-07-29 Nerviano Medical Sciences Srl Process for the preparation of n-[5-(3,5-difluoro-benzyl)-1h-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
PL202899A1 (pl) 1978-08-28
ATA867277A (de) 1980-01-15
DK144972C (da) 1988-08-29
HU174047B (hu) 1979-10-28
JPS6225147B2 (de) 1987-06-01
FI58125C (fi) 1985-01-02
ZA777223B (en) 1978-09-27
SE7713376L (sv) 1978-06-16
DD133671A1 (de) 1979-01-17
NO147244C (no) 1984-10-09
DE2755637A1 (de) 1978-06-22
DK144972B (da) 1982-07-19
DE2755637C2 (de) 1987-09-24
DK558277A (da) 1978-06-16
AT358048B (de) 1980-08-11
NL7713702A (nl) 1978-06-19
JPS5387377A (en) 1978-08-01
CH630625A5 (en) 1982-06-30
FI763613A (fi) 1978-06-16
SU753360A3 (ru) 1980-07-30
SE435284B (sv) 1984-09-17
BE861821A (fr) 1978-03-31
CS195347B2 (en) 1980-01-31
NO147244B (no) 1982-11-22
FI58125B (fi) 1980-08-29
PL106031B1 (pl) 1979-11-30
NO774262L (no) 1978-06-16

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