CA1063936A - Preparation of amorphous solid of macrolide antibiotics - Google Patents

Preparation of amorphous solid of macrolide antibiotics

Info

Publication number
CA1063936A
CA1063936A CA249,607A CA249607A CA1063936A CA 1063936 A CA1063936 A CA 1063936A CA 249607 A CA249607 A CA 249607A CA 1063936 A CA1063936 A CA 1063936A
Authority
CA
Canada
Prior art keywords
cellulose
amorphous solid
macrolide
antibiotic
macrolide antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA249,607A
Other languages
English (en)
French (fr)
Inventor
Takeshi Mayama
Toshiyuki Kobayashi
Toyomi Sato
Akira Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Application granted granted Critical
Publication of CA1063936A publication Critical patent/CA1063936A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA249,607A 1975-04-08 1976-04-05 Preparation of amorphous solid of macrolide antibiotics Expired CA1063936A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4182275A JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid

Publications (1)

Publication Number Publication Date
CA1063936A true CA1063936A (en) 1979-10-09

Family

ID=12618972

Family Applications (1)

Application Number Title Priority Date Filing Date
CA249,607A Expired CA1063936A (en) 1975-04-08 1976-04-05 Preparation of amorphous solid of macrolide antibiotics

Country Status (8)

Country Link
JP (1) JPS51118816A (sv)
CA (1) CA1063936A (sv)
DE (1) DE2615403C2 (sv)
ES (1) ES446801A1 (sv)
FR (1) FR2306705A1 (sv)
GB (1) GB1534070A (sv)
MX (1) MX3401E (sv)
NL (1) NL176270C (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5819844B2 (ja) * 1978-07-13 1983-04-20 三菱自動車工業株式会社 機関用燃料供給装置
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS56103109A (en) * 1979-08-31 1981-08-18 Eisai Co Ltd Ubidecarenone-containing composition having improved dispersion properties
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
US4767789A (en) * 1986-10-21 1988-08-30 American Home Products Corporation (Del.) Spray dried acetaminophen
GB9713730D0 (en) * 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers

Also Published As

Publication number Publication date
NL176270C (nl) 1985-03-18
GB1534070A (en) 1978-11-29
JPS51118816A (en) 1976-10-19
ES446801A1 (es) 1977-06-01
DE2615403A1 (de) 1976-10-28
MX3401E (es) 1980-10-30
FR2306705A1 (fr) 1976-11-05
NL7603635A (nl) 1976-10-12
DE2615403C2 (de) 1982-07-15
FR2306705B1 (sv) 1980-07-18
JPS5545042B2 (sv) 1980-11-15
NL176270B (nl) 1984-10-16

Similar Documents

Publication Publication Date Title
US4127647A (en) Process for preparation of stable amorphous macrolide antibiotic solids
US6346533B1 (en) Intraconazole exhibiting an improved solubility, a method of preparing the same and a pharmaceutical composition for oral administration comprising the same
US5935939A (en) Stabilized dispersions of misoprostol
US5972373A (en) Taste masking pharmaceutical composition for oral administration
US5776495A (en) Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions
US4882144A (en) Solid, rapidly released medicament preparations containing dihydropyridines, and processes for their preparation
US4665081A (en) Solid nifedipine preparations and a process for preparing same
CA1069047A (en) Process for preparing preparations for oral administration
SK280194B6 (sk) Farmaceutický prostriedok s potlačenou horkosťou
US4904668A (en) Benzoyl urea compound
CA1298199C (en) Spray dried acetaminophen
US5739105A (en) Cyclosporin containing composition and process for the preparation thereof
JP2004511561A (ja) 薬剤組成物
KR880004803A (ko) 분무 건조된 아세트아미노펜
CA1063936A (en) Preparation of amorphous solid of macrolide antibiotics
US3962419A (en) Stabilized antibiotic SF-837 preparation
EP0088958B1 (en) Stabilization of azulene derivatives
SE436831B (sv) Forfarande for framstellning av lekemedelsformer for oral administrering
CA2022772A1 (en) Antibiotic composition
KR800000345B1 (ko) 마크로라이드계 항생물질의 비정질고체의 제조방법
JPS565412A (en) Pharmaceutical composition
KR100438485B1 (ko) 아졸류 항진균제의 약제학적 조성물
KR100241652B1 (ko) 이푸리플라본의 경구 투여용 제제의 제조 방법
PL85281B1 (sv)