MX3401E - Procedimiento mejorado para preparar solidos amorfos de antibioticos macrolidos - Google Patents

Procedimiento mejorado para preparar solidos amorfos de antibioticos macrolidos

Info

Publication number
MX3401E
MX3401E MX15676U MX15676U MX3401E MX 3401 E MX3401 E MX 3401E MX 15676 U MX15676 U MX 15676U MX 15676 U MX15676 U MX 15676U MX 3401 E MX3401 E MX 3401E
Authority
MX
Mexico
Prior art keywords
amorphos
preparing solid
improved procedure
antibiotics
macrolid antibiotics
Prior art date
Application number
MX15676U
Other languages
English (en)
Inventor
Akira Okada
Toyomi Sato
Toshiyuki Kobayashi
Takeshi Mayama
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of MX3401E publication Critical patent/MX3401E/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un procedimiento mejorado para preparar sólidos amorfos de antibióticos macrólidos que sean estables con el ,paso del tiempo, caracterizado dicho proceso porque comprende secar a base de rociado una solución constituída por un solvente orgánico volatil de un antibiótico macrólido y cuando menos un polímero de celulosa, conduciéndose dicho rociado a presión atmosférica y a una temperatura que es superior a aproximadamente 60°C.
MX15676U 1975-04-08 1976-04-08 Procedimiento mejorado para preparar solidos amorfos de antibioticos macrolidos MX3401E (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4182275A JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid

Publications (1)

Publication Number Publication Date
MX3401E true MX3401E (es) 1980-10-30

Family

ID=12618972

Family Applications (1)

Application Number Title Priority Date Filing Date
MX15676U MX3401E (es) 1975-04-08 1976-04-08 Procedimiento mejorado para preparar solidos amorfos de antibioticos macrolidos

Country Status (8)

Country Link
JP (1) JPS51118816A (es)
CA (1) CA1063936A (es)
DE (1) DE2615403C2 (es)
ES (1) ES446801A1 (es)
FR (1) FR2306705A1 (es)
GB (1) GB1534070A (es)
MX (1) MX3401E (es)
NL (1) NL176270C (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5819844B2 (ja) * 1978-07-13 1983-04-20 三菱自動車工業株式会社 機関用燃料供給装置
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS56103109A (en) * 1979-08-31 1981-08-18 Eisai Co Ltd Ubidecarenone-containing composition having improved dispersion properties
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
US4767789A (en) * 1986-10-21 1988-08-30 American Home Products Corporation (Del.) Spray dried acetaminophen
GB9713730D0 (en) * 1997-06-30 1997-09-03 Ciba Geigy Ag Organic compounds
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers

Also Published As

Publication number Publication date
DE2615403C2 (de) 1982-07-15
NL176270B (nl) 1984-10-16
DE2615403A1 (de) 1976-10-28
ES446801A1 (es) 1977-06-01
NL7603635A (nl) 1976-10-12
FR2306705A1 (fr) 1976-11-05
FR2306705B1 (es) 1980-07-18
JPS51118816A (en) 1976-10-19
JPS5545042B2 (es) 1980-11-15
GB1534070A (en) 1978-11-29
NL176270C (nl) 1985-03-18
CA1063936A (en) 1979-10-09

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