JPS51118816A - A process for stabilizing non-crystalloidal solid - Google Patents

A process for stabilizing non-crystalloidal solid

Info

Publication number
JPS51118816A
JPS51118816A JP4182275A JP4182275A JPS51118816A JP S51118816 A JPS51118816 A JP S51118816A JP 4182275 A JP4182275 A JP 4182275A JP 4182275 A JP4182275 A JP 4182275A JP S51118816 A JPS51118816 A JP S51118816A
Authority
JP
Japan
Prior art keywords
crystalloidal
solid
stabilizing non
stabilizing
transitted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4182275A
Other languages
English (en)
Other versions
JPS5545042B2 (ja
Inventor
Toyomi Sato
Toshiyuki Kobayashi
Takeshi Mayama
Akira Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP4182275A priority Critical patent/JPS51118816A/ja
Priority to CA249,607A priority patent/CA1063936A/en
Priority to NL7603635A priority patent/NL176270C/xx
Priority to FR7610280A priority patent/FR2306705A1/fr
Priority to ES446801A priority patent/ES446801A1/es
Priority to GB1423476A priority patent/GB1534070A/en
Priority to DE19762615403 priority patent/DE2615403C2/de
Priority to MX15676U priority patent/MX3401E/es
Publication of JPS51118816A publication Critical patent/JPS51118816A/ja
Priority to US05/842,197 priority patent/US4127647A/en
Publication of JPS5545042B2 publication Critical patent/JPS5545042B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
JP4182275A 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid Granted JPS51118816A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP4182275A JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid
CA249,607A CA1063936A (en) 1975-04-08 1976-04-05 Preparation of amorphous solid of macrolide antibiotics
NL7603635A NL176270C (nl) 1975-04-08 1976-04-07 Werkwijze voor het bereiden van een amorf, vast, macrolide antibioticum, en van een geneesmiddel daaruit.
GB1423476A GB1534070A (en) 1975-04-08 1976-04-08 Process for the stability of a macrolide antibiotic
ES446801A ES446801A1 (es) 1975-04-08 1976-04-08 Procedimiento para preparar solidos amorfos de antibioticos macroluro.
FR7610280A FR2306705A1 (fr) 1975-04-08 1976-04-08 Procede pour transformer les antibiotiques de type macrolide en solides amorphes stables
DE19762615403 DE2615403C2 (de) 1975-04-08 1976-04-08 Verfahren zur Herstellung amorpher Macrolidantibiotika von guter Stabilität
MX15676U MX3401E (es) 1975-04-08 1976-04-08 Procedimiento mejorado para preparar solidos amorfos de antibioticos macrolidos
US05/842,197 US4127647A (en) 1975-04-08 1977-10-14 Process for preparation of stable amorphous macrolide antibiotic solids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4182275A JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid

Publications (2)

Publication Number Publication Date
JPS51118816A true JPS51118816A (en) 1976-10-19
JPS5545042B2 JPS5545042B2 (ja) 1980-11-15

Family

ID=12618972

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4182275A Granted JPS51118816A (en) 1975-04-08 1975-04-08 A process for stabilizing non-crystalloidal solid

Country Status (8)

Country Link
JP (1) JPS51118816A (ja)
CA (1) CA1063936A (ja)
DE (1) DE2615403C2 (ja)
ES (1) ES446801A1 (ja)
FR (1) FR2306705A1 (ja)
GB (1) GB1534070A (ja)
MX (1) MX3401E (ja)
NL (1) NL176270C (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256075A (en) * 1978-07-13 1981-03-17 Mitsubishi Jidosha Kogyo Kabushiki Kaisha Fuel feed device for engine
JPS56103109A (en) * 1979-08-31 1981-08-18 Eisai Co Ltd Ubidecarenone-containing composition having improved dispersion properties
JP2006151999A (ja) * 1997-06-30 2006-06-15 Novartis Ag 結晶性マクロライドおよびその調製方法
JP2016196515A (ja) * 1998-09-22 2016-11-24 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 低溶解性化合物の安定な複合体

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
US4767789A (en) * 1986-10-21 1988-08-30 American Home Products Corporation (Del.) Spray dried acetaminophen

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256075A (en) * 1978-07-13 1981-03-17 Mitsubishi Jidosha Kogyo Kabushiki Kaisha Fuel feed device for engine
JPS56103109A (en) * 1979-08-31 1981-08-18 Eisai Co Ltd Ubidecarenone-containing composition having improved dispersion properties
JP2006151999A (ja) * 1997-06-30 2006-06-15 Novartis Ag 結晶性マクロライドおよびその調製方法
JP4504323B2 (ja) * 1997-06-30 2010-07-14 ノバルティス アーゲー 結晶性マクロライドおよびその調製方法
JP2016196515A (ja) * 1998-09-22 2016-11-24 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 低溶解性化合物の安定な複合体

Also Published As

Publication number Publication date
ES446801A1 (es) 1977-06-01
CA1063936A (en) 1979-10-09
GB1534070A (en) 1978-11-29
NL176270C (nl) 1985-03-18
FR2306705B1 (ja) 1980-07-18
MX3401E (es) 1980-10-30
NL176270B (nl) 1984-10-16
DE2615403C2 (de) 1982-07-15
FR2306705A1 (fr) 1976-11-05
DE2615403A1 (de) 1976-10-28
NL7603635A (nl) 1976-10-12
JPS5545042B2 (ja) 1980-11-15

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