CA1039275A - 2-hydroxy-w-aminoalkyl-derivatives of aminoglycoside antibiotics - Google Patents
2-hydroxy-w-aminoalkyl-derivatives of aminoglycoside antibioticsInfo
- Publication number
- CA1039275A CA1039275A CA238,246A CA238246A CA1039275A CA 1039275 A CA1039275 A CA 1039275A CA 238246 A CA238246 A CA 238246A CA 1039275 A CA1039275 A CA 1039275A
- Authority
- CA
- Canada
- Prior art keywords
- amino
- hydroxy
- kanamycin
- formula
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
- C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4641274A GB1464401A (en) | 1974-10-26 | 1974-10-26 | Aminoglycosides |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1039275A true CA1039275A (en) | 1978-09-26 |
Family
ID=10441164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA238,246A Expired CA1039275A (en) | 1974-10-26 | 1975-10-24 | 2-hydroxy-w-aminoalkyl-derivatives of aminoglycoside antibiotics |
Country Status (28)
Country | Link |
---|---|
JP (1) | JPS5519237B2 (fi) |
AR (1) | AR205593A1 (fi) |
AT (1) | AT340051B (fi) |
BE (1) | BE834864A (fi) |
BG (1) | BG24821A3 (fi) |
CA (1) | CA1039275A (fi) |
CH (1) | CH601339A5 (fi) |
CS (1) | CS195712B2 (fi) |
DD (1) | DD122522A5 (fi) |
DE (1) | DE2547738C3 (fi) |
DK (1) | DK147075C (fi) |
EG (1) | EG11975A (fi) |
ES (1) | ES442051A1 (fi) |
FI (1) | FI752951A (fi) |
FR (1) | FR2289202A1 (fi) |
GB (1) | GB1464401A (fi) |
HU (1) | HU172060B (fi) |
IE (1) | IE42452B1 (fi) |
IL (1) | IL48263A (fi) |
LU (1) | LU73644A1 (fi) |
NL (1) | NL162081C (fi) |
NZ (1) | NZ179050A (fi) |
PH (1) | PH12782A (fi) |
PL (1) | PL99933B1 (fi) |
RO (1) | RO72878A (fi) |
SE (1) | SE7511945L (fi) |
SU (1) | SU617017A3 (fi) |
ZA (1) | ZA756326B (fi) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000473B1 (en) * | 1977-06-24 | 1981-03-11 | Scherico Ltd. | Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives |
JPS5488241A (en) * | 1977-12-21 | 1979-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel fortimicin a derivative |
JPS57118475U (fi) * | 1981-01-14 | 1982-07-22 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH606076A5 (fi) * | 1973-08-06 | 1978-10-13 | Scherico Ltd |
-
1974
- 1974-10-26 GB GB4641274A patent/GB1464401A/en not_active Expired
-
1975
- 1975-01-01 AR AR260909A patent/AR205593A1/es active
- 1975-10-06 ZA ZA00756326A patent/ZA756326B/xx unknown
- 1975-10-07 IL IL48263A patent/IL48263A/xx unknown
- 1975-10-16 PH PH17665A patent/PH12782A/en unknown
- 1975-10-22 RO RO7583664A patent/RO72878A/ro unknown
- 1975-10-22 EG EG627/75A patent/EG11975A/xx active
- 1975-10-22 FI FI752951A patent/FI752951A/fi not_active Application Discontinuation
- 1975-10-23 AT AT809575A patent/AT340051B/de not_active IP Right Cessation
- 1975-10-23 CS CS757161A patent/CS195712B2/cs unknown
- 1975-10-24 DK DK481175A patent/DK147075C/da active
- 1975-10-24 JP JP12823775A patent/JPS5519237B2/ja not_active Expired
- 1975-10-24 FR FR7532662A patent/FR2289202A1/fr active Granted
- 1975-10-24 CH CH1380675A patent/CH601339A5/xx not_active IP Right Cessation
- 1975-10-24 DE DE2547738A patent/DE2547738C3/de not_active Expired
- 1975-10-24 PL PL1975184233A patent/PL99933B1/pl unknown
- 1975-10-24 SE SE7511945A patent/SE7511945L/xx unknown
- 1975-10-24 LU LU73644A patent/LU73644A1/xx unknown
- 1975-10-24 ES ES442051A patent/ES442051A1/es not_active Expired
- 1975-10-24 BE BE161248A patent/BE834864A/xx not_active IP Right Cessation
- 1975-10-24 BG BG7500031312A patent/BG24821A3/xx unknown
- 1975-10-24 CA CA238,246A patent/CA1039275A/en not_active Expired
- 1975-10-24 IE IE2316/75A patent/IE42452B1/en unknown
- 1975-10-24 NL NL7512465.A patent/NL162081C/xx not_active IP Right Cessation
- 1975-10-24 NZ NZ179050A patent/NZ179050A/xx unknown
- 1975-10-24 DD DD189046A patent/DD122522A5/xx unknown
- 1975-10-24 HU HU75PI00000496A patent/HU172060B/hu unknown
- 1975-10-24 SU SU752184101A patent/SU617017A3/ru active
Also Published As
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