BRPI9807124B8 - composições compreendendo uma combinação de uma base esfingóide livre e uma ceramida e seus usos. - Google Patents
composições compreendendo uma combinação de uma base esfingóide livre e uma ceramida e seus usos.Info
- Publication number
- BRPI9807124B8 BRPI9807124B8 BRPI9807124A BR9807124A BRPI9807124B8 BR PI9807124 B8 BRPI9807124 B8 BR PI9807124B8 BR PI9807124 A BRPI9807124 A BR PI9807124A BR 9807124 A BR9807124 A BR 9807124A BR PI9807124 B8 BRPI9807124 B8 BR PI9807124B8
- Authority
- BR
- Brazil
- Prior art keywords
- ceramide
- compositions
- sphingoid base
- combination
- free sphingoid
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 title abstract 3
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 title abstract 3
- 229940106189 ceramide Drugs 0.000 title abstract 3
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 title abstract 3
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 title abstract 3
- 150000003410 sphingosines Chemical class 0.000 title abstract 3
- 230000004888 barrier function Effects 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 230000009703 regulation of cell differentiation Effects 0.000 abstract 1
- 230000021014 regulation of cell growth Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97203824 | 1997-12-05 | ||
| PCT/EP1998/008121 WO1999029293A1 (en) | 1997-12-05 | 1998-12-07 | Compositions comprising a combination of a free sphingoid base and a ceramide and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR9807124A BR9807124A (pt) | 2000-01-25 |
| BR9807124B1 BR9807124B1 (pt) | 2013-07-09 |
| BRPI9807124B8 true BRPI9807124B8 (pt) | 2021-05-25 |
Family
ID=8229019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9807124A BRPI9807124B8 (pt) | 1997-12-05 | 1998-12-07 | composições compreendendo uma combinação de uma base esfingóide livre e uma ceramida e seus usos. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030059447A1 (enExample) |
| EP (1) | EP0975325B1 (enExample) |
| JP (1) | JP2001510487A (enExample) |
| KR (1) | KR100639531B1 (enExample) |
| CN (1) | CN1112916C (enExample) |
| BR (1) | BRPI9807124B8 (enExample) |
| DE (1) | DE69818242T2 (enExample) |
| ES (1) | ES2207023T3 (enExample) |
| WO (1) | WO1999029293A1 (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306383B1 (en) * | 1998-09-16 | 2001-10-23 | Wilson T Crandall | Method for topical treatment of scars with protein kinase C inhibitors |
| JP4037577B2 (ja) * | 1999-10-07 | 2008-01-23 | ロレアル | 少なくとも1種のカチオン界面活性剤、液体脂肪アルコールおよびセラミド型の化合物を含む化粧品用組成物およびこれを用いた方法 |
| US6493559B1 (en) * | 2000-01-07 | 2002-12-10 | Motorola, Inc. | Method for receiving SMSCB messages during GPRS/EDGE data transfer mode |
| JP4391668B2 (ja) * | 2000-06-06 | 2009-12-24 | 高砂香料工業株式会社 | 液晶構造を有する脂質組成物 |
| JP4619489B2 (ja) * | 2000-06-13 | 2011-01-26 | 花王株式会社 | 抗かゆみ皮膚外用剤 |
| CA2441893C (en) | 2001-03-26 | 2015-01-20 | Dana-Farber Cancer Institute, Inc. | Method of attenuating reactions to skin irritants |
| US6680062B2 (en) | 2001-10-05 | 2004-01-20 | Color Access, Inc. | Anti-irritating rosacea treatment |
| JP2003155231A (ja) * | 2001-11-20 | 2003-05-27 | Kikkoman Corp | 医薬及び抗アレルギー剤 |
| AU2002354131A1 (en) | 2001-12-10 | 2003-06-23 | Kao Corporation | Ceramide emulsions |
| FR2834213B1 (fr) * | 2001-12-27 | 2004-06-04 | Pharmascience Lab | Composition cosmetique ou pharmaceutique comprenant au moins une alcanolamide pour inhiber la migration des cellules de langerhans, et ses utilisations |
| FR2834216B1 (fr) * | 2001-12-27 | 2004-04-30 | Pharmascience Lab | Composition cosmetique ou pharmaceutique comprenant au moins une oxazoline pour inhiber la migration des cellules de langerhans, et ses utilisations |
| KR100487113B1 (ko) * | 2002-08-03 | 2005-05-03 | 대한민국(관리부서:농촌진흥청) | 백강잠 101a로부터 분리, 정제한 뇌신경성장 촉진물질(4e, 6e, 2s,3r)-2-n-도코사노일-4,6-테트라데카스핀가디에닌 |
| KR100487112B1 (ko) * | 2002-08-03 | 2005-05-03 | 대한민국(관리부서:농촌진흥청) | 백강잠 101a로부터 분리, 정제한 뇌신경성장 촉진물질(4e, 6e, 2s,3r)-2-n-아이코사노일-4,6-테트라데카스핀게닌 |
| AU2003277638A1 (en) * | 2002-11-15 | 2004-06-15 | Kose Corporation | Semitransparent cosmetics |
| DE10255554A1 (de) | 2002-11-28 | 2004-06-17 | Goldschmidt Ag | Emulgator-Wachs-Gele auf Wasserbasis |
| GB0301395D0 (en) * | 2003-01-21 | 2003-02-19 | Univ Aston | Inflammatory disorder treatment |
| FR2855047B1 (fr) * | 2003-05-19 | 2007-11-30 | Oreal | Composition comprenant une base sphingoide, un activateur de la voie des 4-et/ou des 6-hydroxylases et un acide gras, utilisation pour renforcer la fonction barriere de la peau |
| JP3967292B2 (ja) * | 2003-06-10 | 2007-08-29 | 花王株式会社 | 油中水型乳化組成物 |
| CN100473375C (zh) * | 2003-06-10 | 2009-04-01 | 花王株式会社 | 水包油型乳化化妆品 |
| WO2005044217A1 (en) * | 2003-11-11 | 2005-05-19 | Doosan Corporation | Method for preparing phytosphingosine liposome composition |
| CA2587470A1 (en) * | 2004-11-15 | 2006-05-18 | Yissum Research Development Company Of The Hebrew University Of Jerusale M | Combination therapy associating preferably a ceramide with a cytotoxic drug |
| JP4832000B2 (ja) * | 2005-06-02 | 2011-12-07 | 花王株式会社 | 油中水型乳化組成物 |
| JP2007001950A (ja) * | 2005-06-27 | 2007-01-11 | Pola Chem Ind Inc | セラミド含有皮膚外用剤 |
| JP2007104926A (ja) * | 2005-10-12 | 2007-04-26 | Hokkaido Univ | セラミド合成酵素LASS6を用いたフィトセラミドおよびαハイドロキシセラミドの製造方法 |
| WO2008021829A2 (en) * | 2006-08-09 | 2008-02-21 | Lipo Chemicals Inc. | Topical ceramide compositions and methos of use |
| WO2008043386A1 (en) * | 2006-10-13 | 2008-04-17 | Evonik Goldschmidt Gmbh | Skin treatment composition |
| EP2192904B1 (en) * | 2007-08-27 | 2016-08-17 | Auxagen, Inc. | METHODS FOR INHIBITING TGF-beta |
| CN101288640B (zh) * | 2008-05-23 | 2010-12-22 | 海南京润珍珠生物技术股份有限公司 | 一种添加珍珠水解液脂质体的祛痘精华液 |
| EP2341913B1 (en) * | 2008-09-16 | 2014-11-19 | Saint Louis University | Method of enhancing tgf-beta signalling |
| US9445975B2 (en) | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
| JP5503130B2 (ja) * | 2008-10-20 | 2014-05-28 | ユニチカ株式会社 | コラーゲン産生促進剤 |
| FR2963233B1 (fr) | 2010-07-28 | 2014-03-14 | Oreal | Procede pour diminuer les hyperpigmentations post-reactionnelles |
| FR2972112B1 (fr) * | 2011-03-01 | 2020-11-06 | Oreal | Utilisation d'un compose pour le traitement des dermatoses inflammatoires |
| FR2972110B1 (fr) * | 2011-03-01 | 2013-11-15 | Oreal | Procede de traitement cosmetique des rougeurs cutanees |
| WO2013173447A1 (en) * | 2012-05-16 | 2013-11-21 | Archer Daniels Midland Company | Emulsifier for solubilizing polar solvents in oils and polyols |
| MX373575B (es) * | 2013-01-24 | 2020-05-05 | Danstar Ferment A G | Paredes celulares de levadura que comprenden vitamina d2, usos de las mismas y metodo para producir las mismas. |
| US9511144B2 (en) | 2013-03-14 | 2016-12-06 | The Proctor & Gamble Company | Cosmetic compositions and methods providing enhanced penetration of skin care actives |
| KR101682452B1 (ko) * | 2015-03-04 | 2016-12-05 | 주식회사 지오코스 | 피부장벽 회복을 위한 액정 베이스 및 이를 포함하는 화장료 조성물 |
| US11357806B2 (en) * | 2015-11-05 | 2022-06-14 | Macau University Of Science And Technology | Method of isolating sphingolipids from cordyceps and their use |
| CN105496886B (zh) * | 2015-12-29 | 2019-06-25 | 苏州工业园区安诺科斯化妆品研发有限公司 | 植物鞘氨醇护肤液 |
| CN106420605A (zh) * | 2016-09-23 | 2017-02-22 | 苏州药基美研医药科技有限公司 | 基于拟神经酰胺和丹皮酚的皮肤外用制剂及其生产方法 |
| WO2018177730A1 (de) | 2017-03-27 | 2018-10-04 | Evonik Degussa Gmbh | Verfahren und erzeugnis zur herstellung ceramidhaltiger formulierungen |
| JP6746674B2 (ja) * | 2017-12-27 | 2020-08-26 | サンスター株式会社 | 化粧水組成物 |
| KR101899413B1 (ko) * | 2018-05-03 | 2018-09-18 | 주식회사 케어사이드 | 피부 감염의 예방 또는 치료용 조성물 |
| JP6602945B1 (ja) * | 2018-12-18 | 2019-11-06 | 株式会社ジェヌインR&D | セラミド分散組成物 |
| US20200345611A1 (en) | 2019-04-30 | 2020-11-05 | Evonik Operations Gmbh | Composition comprising at least one ceramide, at least one sphingoid base and triethyl citrate |
| CN110742842B (zh) * | 2019-11-12 | 2022-09-13 | 医美生物科技(上海)有限公司 | 一种延缓皮肤老化的精华组合物及其制备方法 |
| US11723895B2 (en) | 2020-03-17 | 2023-08-15 | Enzo Biochem, Inc. | Sphingosine pathway modulating compounds for the treatment of coronavirus infection |
| KR102592150B1 (ko) * | 2020-07-09 | 2023-10-20 | 크로다코리아 주식회사 | 살리실산 유도체를 포함하는 신규한 스핑고지질 및 이를 포함하는 조성물 |
| KR102503769B1 (ko) * | 2020-07-10 | 2023-02-27 | 솔루스바이오텍 주식회사 | 측쇄 지방산을 포함하는 신규한 스핑고지질과 그의 용도 |
| KR102502487B1 (ko) * | 2020-07-14 | 2023-02-23 | 솔루스바이오텍 주식회사 | 신규한 스핑고지질 및 이를 포함하는 피부외용제 조성물 |
| EP3981378A1 (de) | 2020-10-09 | 2022-04-13 | Evonik Operations GmbH | Zusammensetzungen enthaltend ceramid, polyglycerincarbonsäureester und cholesterol |
| WO2022158533A1 (en) * | 2021-01-20 | 2022-07-28 | Ajinomoto Co., Inc. | Cosmetic composition |
| WO2022231448A1 (en) | 2021-04-30 | 2022-11-03 | Carbocode S.A. | Topical compositions comprising (glyco)sphingolipids and/or (glyco)ceramides |
| JP2023033269A (ja) * | 2021-08-28 | 2023-03-10 | ブルネエズ株式会社 | 外用組成物 |
| CN115894270B (zh) * | 2022-10-10 | 2024-09-06 | 深圳市迪克曼生物科技有限公司 | 一种神经酰胺及其制备方法和应用 |
| CN117285432A (zh) * | 2023-02-02 | 2023-12-26 | 深圳市迪克曼生物科技有限公司 | 亚麻籽油神经酰胺及其合成方法与用途 |
| CN116041205A (zh) * | 2023-02-02 | 2023-05-02 | 深圳市迪克曼生物科技有限公司 | 琉璃苣油神经酰胺及其合成方法与用途 |
| CN116003288A (zh) * | 2023-02-02 | 2023-04-25 | 深圳市迪克曼生物科技有限公司 | 南美油藤油神经酰胺及其合成方法与用途 |
| EP4512485A1 (en) | 2023-08-25 | 2025-02-26 | Evonik Operations GmbH | Composition comprising ceramide, glycerol and organic acid |
| WO2025119790A1 (en) | 2023-12-07 | 2025-06-12 | Evonik Operations Gmbh | Composition comprising ceramide and triglyceride |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6126000A (ja) | 1984-07-14 | 1986-02-05 | Furuta Denki Kk | 高温気体移送用送風機 |
| US5565207A (en) * | 1990-09-19 | 1996-10-15 | Pola Kasei Kogyo Kabushiki Kaisha | Scalp moisturizer and external skin preparation |
| ES2098735T3 (es) | 1992-04-03 | 1997-05-01 | Gist Brocades Nv | N-acilacion selectiva de amino-alcoholes. |
| CA2137001C (en) | 1992-06-19 | 1999-05-04 | Peter M. Elias | Lipids for epidermal moisturization and repair of barrier function |
| JPH08502961A (ja) * | 1992-11-03 | 1996-04-02 | クエスト・インターナショナル・ビー・ブイ | フィトスフィンゴシン含有セラミドを合成する方法及び前記セラミドを含有する化粧品組成物 |
| GB9308103D0 (en) * | 1993-04-20 | 1993-06-02 | Unilever Plc | Cosmetic composition |
| WO1995011881A1 (en) | 1993-10-28 | 1995-05-04 | Gist-Brocades N.V. | Phytosphingosine-based ceramide i analogs |
| EP0699181B1 (en) | 1994-03-18 | 1998-04-08 | Gist-Brocades B.V. | Linoleoylamide based ceramide derivative and its use in cosmetic preparations for the treatment of dry skin |
| AU2408995A (en) * | 1994-04-27 | 1995-11-16 | Gist-Brocades B.V. | Short chain 2-hydroxycarboxylic acid-based derivatives of ceramides |
| JP3492696B2 (ja) | 1994-09-30 | 2004-02-03 | コスモフェルム ベースローテン フェンノートシャップ | モノ不飽和脂肪酸を基体としたセラミド3誘導体 |
| BR9506594A (pt) * | 1994-11-28 | 1997-09-16 | Gist Brocades Bv | Composição apropriada para uso tópico |
| FR2730410B1 (fr) * | 1995-02-15 | 1997-03-21 | Oreal | Composition cosmetique comprenant une association de ceramides et son utilisation |
| FR2732680B1 (fr) * | 1995-04-05 | 1997-05-09 | Oreal | Composes de type ceramides, leur procede de preparation et leur utilisation |
| WO1997009307A1 (en) * | 1995-09-01 | 1997-03-13 | Gist-Brocades B.V. | Retinoylamide based derivatives of sphingoid bases |
-
1998
- 1998-12-07 DE DE69818242T patent/DE69818242T2/de not_active Expired - Lifetime
- 1998-12-07 US US09/367,033 patent/US20030059447A1/en not_active Abandoned
- 1998-12-07 ES ES98963566T patent/ES2207023T3/es not_active Expired - Lifetime
- 1998-12-07 CN CN98802328A patent/CN1112916C/zh not_active Expired - Lifetime
- 1998-12-07 WO PCT/EP1998/008121 patent/WO1999029293A1/en not_active Ceased
- 1998-12-07 EP EP98963566A patent/EP0975325B1/en not_active Expired - Lifetime
- 1998-12-07 KR KR1019997006968A patent/KR100639531B1/ko not_active Expired - Lifetime
- 1998-12-07 JP JP53009599A patent/JP2001510487A/ja active Pending
- 1998-12-07 BR BRPI9807124A patent/BRPI9807124B8/pt not_active IP Right Cessation
-
2003
- 2003-06-17 US US10/463,277 patent/US7597899B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001510487A (ja) | 2001-07-31 |
| BR9807124B1 (pt) | 2013-07-09 |
| KR100639531B1 (ko) | 2006-10-27 |
| EP0975325A1 (en) | 2000-02-02 |
| US20030059447A1 (en) | 2003-03-27 |
| DE69818242T2 (de) | 2004-07-01 |
| ES2207023T3 (es) | 2004-05-16 |
| EP0975325B1 (en) | 2003-09-17 |
| US20030215414A1 (en) | 2003-11-20 |
| DE69818242D1 (de) | 2003-10-23 |
| CN1246789A (zh) | 2000-03-08 |
| US7597899B2 (en) | 2009-10-06 |
| WO1999029293A1 (en) | 1999-06-17 |
| KR20000070718A (ko) | 2000-11-25 |
| CN1112916C (zh) | 2003-07-02 |
| BR9807124A (pt) | 2000-01-25 |
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