BRPI1005683A2 - processo livre de células in vitro de produção de um ácido desoxirribonucleio (dna) linear fechado, kit, método de indução de reação imunológica contra um antígeno em um hospedeiro, processo de elaboração de uma composição farmacêutica e uso de uma molécula de dna linear fechado na fabricação de um medicamento - Google Patents

processo livre de células in vitro de produção de um ácido desoxirribonucleio (dna) linear fechado, kit, método de indução de reação imunológica contra um antígeno em um hospedeiro, processo de elaboração de uma composição farmacêutica e uso de uma molécula de dna linear fechado na fabricação de um medicamento

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Publication number
BRPI1005683A2
BRPI1005683A2 BRPI1005683-1A BRPI1005683A BRPI1005683A2 BR PI1005683 A2 BRPI1005683 A2 BR PI1005683A2 BR PI1005683 A BRPI1005683 A BR PI1005683A BR PI1005683 A2 BRPI1005683 A2 BR PI1005683A2
Authority
BR
Brazil
Prior art keywords
dna
closed linear
kit
deoxyribonucleic acid
antigen
Prior art date
Application number
BRPI1005683-1A
Other languages
English (en)
Inventor
Hill Vanessa
Original Assignee
Touchlight Genetics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40469378&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1005683(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Touchlight Genetics Limited filed Critical Touchlight Genetics Limited
Publication of BRPI1005683A2 publication Critical patent/BRPI1005683A2/pt
Publication of BRPI1005683B1 publication Critical patent/BRPI1005683B1/pt

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • A—HUMAN NECESSITIES
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase

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Abstract

processo livre de células in vitro de produção de um ácido desoxirribonucleico (dna) linear fechado, kit, método de indução de reação imunológica contra um antígeno em um hospedeiro, processo de elaboração de uma composição farmacêutica e uso de uma molécula de dna linear fechado na fabricação de um medicamento processo in vitro de produção de ácido desoxirribonucleico (dna) linear fechado compreende (a) contato de um modelo de dna que compreende pelo menos uma sequência alvo de protelomerase com pelo menos uma dna polimerase na presença de um ou mais primers sob condições que promovam a amplificação do mencionado modelo; e (b) contato de dna amplificado produzido em (a) com pelo menos uma protelomerase sob condições que promovam a formação de dna linear fechado. um kit fornece os componentes necessários no processo.
BRPI1005683-1A 2009-01-30 2010-02-01 processo in vitro, livre de células, para a produção de um ácido desoxirribonucleico (dna) linear fechado BRPI1005683B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0901593.4A GB0901593D0 (en) 2009-01-30 2009-01-30 Production of closed linear DNA
GB0901593.4 2009-01-30
PCT/GB2010/000165 WO2010086626A1 (en) 2009-01-30 2010-02-01 Production of closed linear dna

Publications (2)

Publication Number Publication Date
BRPI1005683A2 true BRPI1005683A2 (pt) 2019-04-02
BRPI1005683B1 BRPI1005683B1 (pt) 2019-11-12

Family

ID=40469378

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1005683-1A BRPI1005683B1 (pt) 2009-01-30 2010-02-01 processo in vitro, livre de células, para a produção de um ácido desoxirribonucleico (dna) linear fechado

Country Status (20)

Country Link
US (4) US9109250B2 (pt)
EP (3) EP2391731B1 (pt)
JP (2) JP2012516147A (pt)
KR (1) KR101926662B1 (pt)
CN (2) CN102301010B (pt)
AU (1) AU2010209532B2 (pt)
BR (1) BRPI1005683B1 (pt)
CA (1) CA2751130C (pt)
DK (2) DK3150722T3 (pt)
EA (1) EA021069B1 (pt)
ES (2) ES2749629T3 (pt)
GB (1) GB0901593D0 (pt)
HK (1) HK1159693A1 (pt)
IL (1) IL213930A (pt)
LT (1) LT3150722T (pt)
MX (1) MX2011007937A (pt)
NZ (1) NZ594004A (pt)
SG (1) SG173102A1 (pt)
WO (1) WO2010086626A1 (pt)
ZA (1) ZA201105013B (pt)

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