BRPI0913949A2 - preparação e composição de proteínas inibidoras inter-alfa a partir de sangue - Google Patents

preparação e composição de proteínas inibidoras inter-alfa a partir de sangue

Info

Publication number
BRPI0913949A2
BRPI0913949A2 BRPI0913949A BRPI0913949A BRPI0913949A2 BR PI0913949 A2 BRPI0913949 A2 BR PI0913949A2 BR PI0913949 A BRPI0913949 A BR PI0913949A BR PI0913949 A BRPI0913949 A BR PI0913949A BR PI0913949 A2 BRPI0913949 A2 BR PI0913949A2
Authority
BR
Brazil
Prior art keywords
inter
blood
preparation
composition
alpha inhibitor
Prior art date
Application number
BRPI0913949A
Other languages
English (en)
Inventor
Edward S Sirya
Peter Brne
Yow-Pin Lim
Original Assignee
Pro Thera Biolog Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pro Thera Biolog Llc filed Critical Pro Thera Biolog Llc
Publication of BRPI0913949A2 publication Critical patent/BRPI0913949A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
BRPI0913949A 2008-05-28 2009-05-28 preparação e composição de proteínas inibidoras inter-alfa a partir de sangue BRPI0913949A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13026908P 2008-05-28 2008-05-28
PCT/US2009/003291 WO2009154695A1 (en) 2008-05-28 2009-05-28 Preparation and composition of inter-alpha inhibitor proteins from blood

Publications (1)

Publication Number Publication Date
BRPI0913949A2 true BRPI0913949A2 (pt) 2015-10-20

Family

ID=41434346

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913949A BRPI0913949A2 (pt) 2008-05-28 2009-05-28 preparação e composição de proteínas inibidoras inter-alfa a partir de sangue

Country Status (13)

Country Link
US (3) US9139641B2 (pt)
EP (1) EP2291654B1 (pt)
JP (3) JP5793076B2 (pt)
KR (3) KR20170116196A (pt)
CN (2) CN102112876B (pt)
AU (1) AU2009260822B2 (pt)
BR (1) BRPI0913949A2 (pt)
CA (1) CA2726281C (pt)
DK (1) DK2291654T3 (pt)
ES (1) ES2673005T3 (pt)
PT (1) PT2291654T (pt)
TR (1) TR201808152T4 (pt)
WO (1) WO2009154695A1 (pt)

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NZ546942A (en) 2003-11-08 2010-03-26 Prothera Biolog Preparation and composition of inter-alpha inhibitor proteins from human plasma for therapeutic use
CA2726281C (en) 2008-05-28 2023-04-18 Prothera Biologics, Llc Preparation and composition of inter-alpha inhibitor proteins from blood
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
WO2011150284A2 (en) 2010-05-26 2011-12-01 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
KR20130093607A (ko) 2010-07-23 2013-08-22 백스터 인터내셔널 인코포레이티드 혈장으로부터 인터-알파-억제제 단백질 (iaip)의 제조
KR101443257B1 (ko) * 2011-10-18 2014-09-19 주식회사 종근당 낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법
AU2013312215C1 (en) * 2012-09-09 2018-09-06 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
US20140206844A1 (en) * 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
DK3041857T3 (da) * 2013-09-04 2019-07-22 Emd Millipore Corp Protein a-kromatografi
HUE057005T2 (hu) * 2013-09-25 2022-04-28 Bioverativ Therapeutics Inc Oszlopon történõ vírusinaktiváló eljárások
CN104138374A (zh) * 2014-07-26 2014-11-12 滨州医学院 硫酸阿扎那韦在制备预防或治疗内毒素血症和脓毒症的药物中的应用
US10809247B2 (en) * 2015-10-15 2020-10-20 Plasma Technologies, Llc Methods for extracting proteins from blood plasma
KR102587810B1 (ko) * 2017-04-25 2023-10-11 프로테라 바이오로직스, 인크. 인터-알파 억제제 단백질을 정량화하는 방법
EP3714036A1 (en) * 2017-11-20 2020-09-30 Lonza Ltd Process and system for propagating cell cultures while preventing lactate accumulation
US20210393750A1 (en) * 2018-10-24 2021-12-23 Prothera Biologics, Inc. Inter-alpha inhibitor proteins and methods of use thereof
CN109900689B (zh) * 2019-03-28 2021-12-10 复星诊断科技(长沙)有限公司 抗干扰膜及肝功能联合测试条
JP2023549538A (ja) 2020-11-16 2023-11-27 プロセラ バイオロジクス， インク． インターアルファインヒビタータンパク質の精製方法
WO2023089503A1 (en) * 2021-11-16 2023-05-25 Takeda Pharmaceutical Company Limited Inter-alpha inhibitor protein formulations

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US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material

Also Published As

Publication number Publication date
JP2015155434A (ja) 2015-08-27
EP2291654A1 (en) 2011-03-09
TR201808152T4 (tr) 2018-07-23
KR20160129914A (ko) 2016-11-09
EP2291654B1 (en) 2018-04-11
CN102112876B (zh) 2017-12-08
JP6309915B2 (ja) 2018-04-11
CN106928346B (zh) 2021-09-07
CA2726281C (en) 2023-04-18
US9758570B2 (en) 2017-09-12
KR101828433B1 (ko) 2018-03-29
ES2673005T3 (es) 2018-06-19
KR101714008B1 (ko) 2017-03-09
CN102112876A (zh) 2011-06-29
KR20170116196A (ko) 2017-10-18
CA2726281A1 (en) 2009-12-23
AU2009260822B2 (en) 2016-09-22
JP2018008941A (ja) 2018-01-18
US20170157224A1 (en) 2017-06-08
AU2009260822A1 (en) 2009-12-23
US20160145318A1 (en) 2016-05-26
JP2011524343A (ja) 2011-09-01
US20110190194A1 (en) 2011-08-04
EP2291654A4 (en) 2011-08-24
WO2009154695A1 (en) 2009-12-23
JP5793076B2 (ja) 2015-10-14
PT2291654T (pt) 2018-06-15
KR20110053404A (ko) 2011-05-23
CN106928346A (zh) 2017-07-07
US10076559B2 (en) 2018-09-18
US9139641B2 (en) 2015-09-22
DK2291654T3 (en) 2018-06-14

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: PROTHERA BIOLOGICS, INC. (US)

B25G Requested change of headquarter approved

Owner name: PROTHERA BIOLOGICS, INC. (US)

B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]