PT2291654T - Preparação e composição de proteínas inibidoras de interalfa do sangue - Google Patents

Preparação e composição de proteínas inibidoras de interalfa do sangue

Info

Publication number
PT2291654T
PT2291654T PT97670087T PT09767008T PT2291654T PT 2291654 T PT2291654 T PT 2291654T PT 97670087 T PT97670087 T PT 97670087T PT 09767008 T PT09767008 T PT 09767008T PT 2291654 T PT2291654 T PT 2291654T
Authority
PT
Portugal
Prior art keywords
inter
blood
preparation
composition
alpha inhibitor
Prior art date
Application number
PT97670087T
Other languages
English (en)
Inventor
Lim Yow-Pin
S Sirya Edward
Brne Peter
Original Assignee
Prothera Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothera Biologics Inc filed Critical Prothera Biologics Inc
Publication of PT2291654T publication Critical patent/PT2291654T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT97670087T 2008-05-28 2009-05-28 Preparação e composição de proteínas inibidoras de interalfa do sangue PT2291654T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13026908P 2008-05-28 2008-05-28

Publications (1)

Publication Number Publication Date
PT2291654T true PT2291654T (pt) 2018-06-15

Family

ID=41434346

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97670087T PT2291654T (pt) 2008-05-28 2009-05-28 Preparação e composição de proteínas inibidoras de interalfa do sangue

Country Status (13)

Country Link
US (3) US9139641B2 (pt)
EP (1) EP2291654B1 (pt)
JP (3) JP5793076B2 (pt)
KR (3) KR20170116196A (pt)
CN (2) CN102112876B (pt)
AU (1) AU2009260822B2 (pt)
BR (2) BR122020017577B1 (pt)
CA (1) CA2726281C (pt)
DK (1) DK2291654T3 (pt)
ES (1) ES2673005T3 (pt)
PT (1) PT2291654T (pt)
TR (1) TR201808152T4 (pt)
WO (1) WO2009154695A1 (pt)

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EP1691820A4 (en) 2003-11-08 2010-03-03 Prothera Biolog PREPARATION AND COMPOSITION OF INTER-ALPHA INHIBITOR PROTEINS FROM HUMAN PLASMA FOR THERAPEUTIC USE
TR201808152T4 (tr) 2008-05-28 2018-07-23 Prothera Biologics Inc Kandan inter-alfa inhibitör proteinlerinin hazırlanması ve bunların bileşimi.
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
WO2011150284A2 (en) 2010-05-26 2011-12-01 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
CN103119058A (zh) * 2010-07-23 2013-05-22 巴克斯特国际公司 由血浆生产间-α-抑制蛋白(IAIP)
KR101443257B1 (ko) * 2011-10-18 2014-09-19 주식회사 종근당 낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법
AU2013312215C1 (en) 2012-09-09 2018-09-06 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
US20140206844A1 (en) * 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material
ES2737078T3 (es) * 2013-09-04 2020-01-10 Emd Millipore Corp Cromatografía de Proteína A
EP3903599A1 (en) * 2013-09-25 2021-11-03 Bioverativ Therapeutics Inc. On-column viral inactivation methods
CN104138374A (zh) * 2014-07-26 2014-11-12 滨州医学院 硫酸阿扎那韦在制备预防或治疗内毒素血症和脓毒症的药物中的应用
US10809247B2 (en) * 2015-10-15 2020-10-20 Plasma Technologies, Llc Methods for extracting proteins from blood plasma
KR102587810B1 (ko) * 2017-04-25 2023-10-11 프로테라 바이오로직스, 인크. 인터-알파 억제제 단백질을 정량화하는 방법
CN111630148A (zh) * 2017-11-20 2020-09-04 隆萨有限公司 在防止乳酸积累的同时繁殖细胞培养物的过程和系统
WO2020086879A1 (en) * 2018-10-24 2020-04-30 Prothera Biologics, Inc. Inter-alpha inhibitor proteins and methods of use thereof
CN109900689B (zh) * 2019-03-28 2021-12-10 复星诊断科技(长沙)有限公司 抗干扰膜及肝功能联合测试条
WO2022104282A1 (en) 2020-11-16 2022-05-19 Prothera Biologics, Inc. Methods for purifying inter-alpha inhibitor proteins
WO2023089503A1 (en) * 2021-11-16 2023-05-25 Takeda Pharmaceutical Company Limited Inter-alpha inhibitor protein formulations

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CN103119058A (zh) 2010-07-23 2013-05-22 巴克斯特国际公司 由血浆生产间-α-抑制蛋白(IAIP)
AU2013312215C1 (en) 2012-09-09 2018-09-06 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
US20140206844A1 (en) 2013-01-18 2014-07-24 Prothera Biologics Methods for isolating blood products from an inter-alpha inhibitor protein-depleted blood product material

Also Published As

Publication number Publication date
CN106928346B (zh) 2021-09-07
CA2726281A1 (en) 2009-12-23
CN102112876A (zh) 2011-06-29
CN106928346A (zh) 2017-07-07
KR20160129914A (ko) 2016-11-09
JP2018008941A (ja) 2018-01-18
KR101828433B1 (ko) 2018-03-29
BRPI0913949A2 (pt) 2015-10-20
JP6309915B2 (ja) 2018-04-11
ES2673005T3 (es) 2018-06-19
EP2291654A1 (en) 2011-03-09
KR20110053404A (ko) 2011-05-23
JP5793076B2 (ja) 2015-10-14
AU2009260822A1 (en) 2009-12-23
KR20170116196A (ko) 2017-10-18
DK2291654T3 (en) 2018-06-14
KR101714008B1 (ko) 2017-03-09
AU2009260822B2 (en) 2016-09-22
EP2291654B1 (en) 2018-04-11
WO2009154695A1 (en) 2009-12-23
US9139641B2 (en) 2015-09-22
US20160145318A1 (en) 2016-05-26
CA2726281C (en) 2023-04-18
US9758570B2 (en) 2017-09-12
US20170157224A1 (en) 2017-06-08
CN102112876B (zh) 2017-12-08
JP2011524343A (ja) 2011-09-01
US10076559B2 (en) 2018-09-18
TR201808152T4 (tr) 2018-07-23
US20110190194A1 (en) 2011-08-04
EP2291654A4 (en) 2011-08-24
JP2015155434A (ja) 2015-08-27
BR122020017577B1 (pt) 2021-10-26

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