BRPI0912482A2 - composições de corticosteróide de liberação controlada e métodos para o tratamento de distúrbios auriculares - Google Patents

composições de corticosteróide de liberação controlada e métodos para o tratamento de distúrbios auriculares Download PDF

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Publication number
BRPI0912482A2
BRPI0912482A2 BRPI0912482-9A BRPI0912482A BRPI0912482A2 BR PI0912482 A2 BRPI0912482 A2 BR PI0912482A2 BR PI0912482 A BRPI0912482 A BR PI0912482A BR PI0912482 A2 BRPI0912482 A2 BR PI0912482A2
Authority
BR
Brazil
Prior art keywords
formulation
formulations
corticosteroid
dexamethasone
ear
Prior art date
Application number
BRPI0912482-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Jay Lichter
Jeffrey P. Harris
Benedikt VOLLRATH
Andrew M. Trammel
Sergio G. Durón
Fabrice Piu
Luis A. Dellamary
Qiang Ye
Carl LEBEL
Michael Christopher SCAIFE
Original Assignee
Otonomy, Inc
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41319223&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0912482(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0823378A external-priority patent/GB2459910B/en
Application filed by Otonomy, Inc, The Regents Of The University Of California filed Critical Otonomy, Inc
Publication of BRPI0912482A2 publication Critical patent/BRPI0912482A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0912482-9A 2008-05-14 2009-05-14 composições de corticosteróide de liberação controlada e métodos para o tratamento de distúrbios auriculares BRPI0912482A2 (pt)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US12771308P 2008-05-14 2008-05-14
US61/127,713 2008-05-14
US6042508P 2008-06-10 2008-06-10
US61/060,425 2008-06-10
US7458308P 2008-06-20 2008-06-20
US61/074,583 2008-06-20
US8245008P 2008-07-21 2008-07-21
US61/082,450 2008-07-21
US8794008P 2008-08-11 2008-08-11
US61/087,940 2008-08-11
US9438408P 2008-09-04 2008-09-04
US61/094,384 2008-09-04
US9524808P 2008-09-08 2008-09-08
US61/095,248 2008-09-08
US10111208P 2008-09-29 2008-09-29
US61/101,112 2008-09-29
US14003308P 2008-12-22 2008-12-22
GB0823378A GB2459910B (en) 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
US61/140,033 2008-12-22
GB0823378.5 2008-12-22
PCT/US2009/003066 WO2009139924A2 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders

Publications (1)

Publication Number Publication Date
BRPI0912482A2 true BRPI0912482A2 (pt) 2020-08-18

Family

ID=41319223

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0912482-9A BRPI0912482A2 (pt) 2008-05-14 2009-05-14 composições de corticosteróide de liberação controlada e métodos para o tratamento de distúrbios auriculares

Country Status (14)

Country Link
US (9) US8030297B2 (enExample)
EP (1) EP2303227B1 (enExample)
JP (3) JP5551685B2 (enExample)
KR (2) KR101534422B1 (enExample)
CN (2) CN102026623B (enExample)
AU (1) AU2009246870B2 (enExample)
BR (1) BRPI0912482A2 (enExample)
CA (1) CA2723458C (enExample)
IL (2) IL208806A (enExample)
MX (1) MX2010012397A (enExample)
MY (1) MY161021A (enExample)
RU (2) RU2469726C2 (enExample)
WO (1) WO2009139924A2 (enExample)
ZA (1) ZA201007482B (enExample)

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