BRPI0819231B8 - processo para preparo de forma farmacêutica de desintegração rápida por moldagem a quente na presença de sal inorgânico hidratado - Google Patents

processo para preparo de forma farmacêutica de desintegração rápida por moldagem a quente na presença de sal inorgânico hidratado

Info

Publication number
BRPI0819231B8
BRPI0819231B8 BRPI0819231A BRPI0819231A BRPI0819231B8 BR PI0819231 B8 BRPI0819231 B8 BR PI0819231B8 BR PI0819231 A BRPI0819231 A BR PI0819231A BR PI0819231 A BRPI0819231 A BR PI0819231A BR PI0819231 B8 BRPI0819231 B8 BR PI0819231B8
Authority
BR
Brazil
Prior art keywords
inorganic salt
pharmaceutical form
fast disintegrating
hot molding
hydrated inorganic
Prior art date
Application number
BRPI0819231A
Other languages
English (en)
Inventor
Bunick Frank
Luber Joseph
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of BRPI0819231A2 publication Critical patent/BRPI0819231A2/pt
Publication of BRPI0819231B1 publication Critical patent/BRPI0819231B1/pt
Publication of BRPI0819231B8 publication Critical patent/BRPI0819231B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

forma de dosagem de desintegração oral. a presente invenção refere-se a uma forma de dosagem de desintegração oral incluindo cerca de 5% a cerca de 40%, em peso, de pelo menos um sal hidratado e um agente farmaceuticamente ativo, em que o dito pelo menos um sal hidratado tem um temperatura de desidratação de cerca de 20 a cerca de 120°c.
BRPI0819231A 2007-10-31 2008-10-29 processo para preparo de forma farmacêutica de desintegração rápida por moldagem a quente na presença de sal inorgânico hidratado BRPI0819231B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98397307P 2007-10-31 2007-10-31
US60/983,973 2007-10-31
PCT/US2008/081496 WO2009058798A2 (en) 2007-10-31 2008-10-29 Orally disintegrated dosage form

Publications (3)

Publication Number Publication Date
BRPI0819231A2 BRPI0819231A2 (pt) 2015-05-05
BRPI0819231B1 BRPI0819231B1 (pt) 2019-04-30
BRPI0819231B8 true BRPI0819231B8 (pt) 2021-05-25

Family

ID=40184970

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819231A BRPI0819231B8 (pt) 2007-10-31 2008-10-29 processo para preparo de forma farmacêutica de desintegração rápida por moldagem a quente na presença de sal inorgânico hidratado

Country Status (13)

Country Link
US (3) US20090110716A1 (pt)
EP (1) EP2217213B1 (pt)
KR (1) KR101560176B1 (pt)
CN (1) CN101842085B (pt)
AR (1) AR069128A1 (pt)
AU (1) AU2008318851B2 (pt)
BR (1) BRPI0819231B8 (pt)
CA (1) CA2704209C (pt)
ES (1) ES2633449T3 (pt)
HK (1) HK1147202A1 (pt)
MX (1) MX2010004897A (pt)
RU (1) RU2482839C2 (pt)
WO (1) WO2009058798A2 (pt)

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EP4171518A1 (en) 2020-06-26 2023-05-03 Aprecia Pharmaceuticals LLC Rapidly-orodispersible tablets having an interior cavity

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AR069128A1 (es) 2009-12-30
MX2010004897A (es) 2010-05-19
BRPI0819231B1 (pt) 2019-04-30
AU2008318851B2 (en) 2014-04-17
EP2217213A2 (en) 2010-08-18
EP2217213B1 (en) 2017-05-24
US20100016451A1 (en) 2010-01-21
CN101842085B (zh) 2013-01-30
CA2704209C (en) 2017-02-28
US8968769B2 (en) 2015-03-03
AU2008318851A1 (en) 2009-05-07
HK1147202A1 (en) 2011-08-05
BRPI0819231A2 (pt) 2015-05-05
US20090110716A1 (en) 2009-04-30
CA2704209A1 (en) 2009-05-07
KR101560176B1 (ko) 2015-10-14
WO2009058798A2 (en) 2009-05-07
WO2009058798A3 (en) 2009-08-27
RU2010121887A (ru) 2011-12-10
RU2482839C2 (ru) 2013-05-27
KR20100096120A (ko) 2010-09-01
US20100016348A1 (en) 2010-01-21
ES2633449T3 (es) 2017-09-21

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