BRPI0817941A2 - Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide - Google Patents

Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide

Info

Publication number
BRPI0817941A2
BRPI0817941A2 BRPI0817941A BRPI0817941A2 BR PI0817941 A2 BRPI0817941 A2 BR PI0817941A2 BR PI0817941 A BRPI0817941 A BR PI0817941A BR PI0817941 A2 BRPI0817941 A2 BR PI0817941A2
Authority
BR
Brazil
Prior art keywords
steroidal
pyrazole compounds
glucocorticoid activity
glucocorticoid
activity
Prior art date
Application number
Other languages
English (en)
Portuguese (pt)
Inventor
Hakan Bladh
Frank Burkamp
Balint Gabos
Peter Hansen
Svetlana Ivanova
Karolina Lawitz
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40328402&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0817941(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0817941A2 publication Critical patent/BRPI0817941A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0817941 2007-10-04 2008-10-02 Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide BRPI0817941A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97741607P 2007-10-04 2007-10-04
PCT/GB2008/050890 WO2009044200A1 (en) 2007-10-04 2008-10-02 Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity

Publications (1)

Publication Number Publication Date
BRPI0817941A2 true BRPI0817941A2 (pt) 2015-05-05

Family

ID=40328402

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0817941 BRPI0817941A2 (pt) 2007-10-04 2008-10-02 Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide

Country Status (23)

Country Link
US (2) US8163724B2 (https=)
EP (1) EP2207788A1 (https=)
JP (1) JP2010540612A (https=)
KR (1) KR20100087147A (https=)
CN (1) CN101883778A (https=)
AR (1) AR068734A1 (https=)
AU (1) AU2008306593C1 (https=)
BR (1) BRPI0817941A2 (https=)
CA (1) CA2700181A1 (https=)
CL (1) CL2008002954A1 (https=)
CO (1) CO6270214A2 (https=)
CR (1) CR11345A (https=)
DO (1) DOP2010000094A (https=)
EA (1) EA201000436A1 (https=)
IL (1) IL204611A0 (https=)
MX (1) MX2010003698A (https=)
NI (1) NI201000043A (https=)
NZ (1) NZ584160A (https=)
PE (1) PE20090776A1 (https=)
TW (1) TW200918047A (https=)
UY (1) UY31375A1 (https=)
WO (1) WO2009044200A1 (https=)
ZA (1) ZA201002223B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ584160A (en) 2007-10-04 2011-05-27 Astrazeneca Ab Steroidal [3,2-c] pyrazole compounds, with glucocorticoid activity
CN101945885A (zh) * 2007-12-20 2011-01-12 阿斯利康(瑞典)有限公司 用作糖皮质激素受体激动剂的甾类衍生物
UY32520A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32525A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32521A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
UY32523A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
JP2012530140A (ja) 2009-06-16 2012-11-29 メルク・シャープ・アンド・ドーム・コーポレーション グルココルチコイド受容体アゴニストとしての新規［３，２−ｃ］ヘテロアリールステロイド、組成物およびこの使用
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
AU2011263416B2 (en) 2010-06-11 2014-04-10 Rhodes Technologies Process for N-dealkylation of tertiary amines
GB201016912D0 (en) * 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
US8829024B2 (en) * 2011-01-07 2014-09-09 Corcept Therapeutics, Inc. Combination steroid and glucocorticoid receptor antagonist therapy
KR101834362B1 (ko) 2011-03-18 2018-03-05 바이엘 인텔렉쳐 프로퍼티 게엠베하 N-(3-카바모일페닐)-1h-피라졸-5-카복사미드 유도체 및 동물 해충을 구제하기 위한 그의 용도
US9526729B2 (en) * 2013-01-29 2016-12-27 Hsiao Lily Yu Medicament for treating peripheral neuropathies
JP2016531852A (ja) * 2013-09-25 2016-10-13 ヴァン アンデル リサーチ インスティテュート 非常に強力なグルココルチコイド
CN110382033B (zh) * 2016-10-14 2022-04-15 范安德尔研究所 用于设计高效力糖皮质激素的结构与机制

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WO1994025478A1 (en) 1993-04-29 1994-11-10 Instytut Farmaceutyczny 16α,17α-ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES
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BR9707495A (pt) 1996-02-13 1999-07-27 Zeneca Ltd Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
US6291455B1 (en) 1996-03-05 2001-09-18 Zeneca Limited 4-anilinoquinazoline derivatives
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WO2007054974A2 (en) 2005-09-28 2007-05-18 Arch Pharmalab Limited A green chemistry process for the preparation of pregnadiene esters
NZ584160A (en) 2007-10-04 2011-05-27 Astrazeneca Ab Steroidal [3,2-c] pyrazole compounds, with glucocorticoid activity
CN101945885A (zh) 2007-12-20 2011-01-12 阿斯利康(瑞典)有限公司 用作糖皮质激素受体激动剂的甾类衍生物
BRPI0907789A2 (pt) 2008-02-27 2019-01-22 Astrazeneca Ab derivaldos 16-alfa e 17-alfa de glicocorticosteroides e seus usos
UY32520A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32523A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32521A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
UY32525A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides

Also Published As

Publication number Publication date
PE20090776A1 (es) 2009-07-23
AU2008306593B2 (en) 2012-04-12
CR11345A (es) 2010-07-15
EP2207788A1 (en) 2010-07-21
EA201000436A1 (ru) 2010-10-29
US8163724B2 (en) 2012-04-24
US20090286835A1 (en) 2009-11-19
WO2009044200A1 (en) 2009-04-09
NI201000043A (es) 2012-09-10
US20120178726A1 (en) 2012-07-12
AU2008306593A1 (en) 2009-04-09
CO6270214A2 (es) 2011-04-20
AR068734A1 (es) 2009-12-02
KR20100087147A (ko) 2010-08-03
UY31375A1 (es) 2009-05-29
MX2010003698A (es) 2010-04-21
JP2010540612A (ja) 2010-12-24
CA2700181A1 (en) 2009-04-09
TW200918047A (en) 2009-05-01
CL2008002954A1 (es) 2010-01-15
AU2008306593C1 (en) 2012-10-04
IL204611A0 (en) 2010-11-30
DOP2010000094A (es) 2012-08-15
ZA201002223B (en) 2010-12-29
CN101883778A (zh) 2010-11-10
NZ584160A (en) 2011-05-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.