BRPI0817941A2 - Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide - Google Patents

Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide

Info

Publication number
BRPI0817941A2
BRPI0817941A2 BRPI0817941A BRPI0817941A2 BR PI0817941 A2 BRPI0817941 A2 BR PI0817941A2 BR PI0817941 A BRPI0817941 A BR PI0817941A BR PI0817941 A2 BRPI0817941 A2 BR PI0817941A2
Authority
BR
Brazil
Prior art keywords
steroidal
pyrazole compounds
glucocorticoid activity
glucocorticoid
activity
Prior art date
Application number
Other languages
English (en)
Inventor
Hakan Bladh
Frank Burkamp
Balint Gabos
Peter Hansen
Svetlana Ivanova
Karolina Lawitz
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40328402&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0817941(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0817941A2 publication Critical patent/BRPI0817941A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0817941 2007-10-04 2008-10-02 Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide BRPI0817941A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97741607P 2007-10-04 2007-10-04
PCT/GB2008/050890 WO2009044200A1 (en) 2007-10-04 2008-10-02 Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity

Publications (1)

Publication Number Publication Date
BRPI0817941A2 true BRPI0817941A2 (pt) 2015-05-05

Family

ID=40328402

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0817941 BRPI0817941A2 (pt) 2007-10-04 2008-10-02 Compostos de pirazol de [3,2-c] esteroidais, com atividade glucocorticóide

Country Status (23)

Country Link
US (2) US8163724B2 (pt)
EP (1) EP2207788A1 (pt)
JP (1) JP2010540612A (pt)
KR (1) KR20100087147A (pt)
CN (1) CN101883778A (pt)
AR (1) AR068734A1 (pt)
AU (1) AU2008306593C1 (pt)
BR (1) BRPI0817941A2 (pt)
CA (1) CA2700181A1 (pt)
CL (1) CL2008002954A1 (pt)
CO (1) CO6270214A2 (pt)
CR (1) CR11345A (pt)
DO (1) DOP2010000094A (pt)
EA (1) EA201000436A1 (pt)
IL (1) IL204611A0 (pt)
MX (1) MX2010003698A (pt)
NI (1) NI201000043A (pt)
NZ (1) NZ584160A (pt)
PE (1) PE20090776A1 (pt)
TW (1) TW200918047A (pt)
UY (1) UY31375A1 (pt)
WO (1) WO2009044200A1 (pt)
ZA (1) ZA201002223B (pt)

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* Cited by examiner, † Cited by third party
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KR20100087147A (ko) 2007-10-04 2010-08-03 아스트라제네카 아베 글루코코르티코이드 활성을 갖는 스테로이드성 [3,2-ｃ]피라졸 화합물
JP2011507836A (ja) * 2007-12-20 2011-03-10 アストラゼネカ・アクチエボラーグ グルココルチコステロイド受容体アゴニストとして作用するステロイド誘導体
UY32520A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32525A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32523A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32521A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
AR077101A1 (es) 2009-06-16 2011-08-03 Schering Corp Esteroides de heteroarilo (3,2-c), como agonistas de receptor glucocorticoide, composiciones y usos de los mismos
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
AU2011263416B2 (en) 2010-06-11 2014-04-10 Rhodes Technologies Process for N-dealkylation of tertiary amines
GB201016912D0 (en) * 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
US8829024B2 (en) * 2011-01-07 2014-09-09 Corcept Therapeutics, Inc. Combination steroid and glucocorticoid receptor antagonist therapy
CN103502221B (zh) 2011-03-18 2016-03-30 拜耳知识产权有限责任公司 N-(3-氨甲酰基苯基)-1h-吡唑-5-甲酰胺衍生物及其用于防治动物害虫的用途
US9526729B2 (en) * 2013-01-29 2016-12-27 Hsiao Lily Yu Medicament for treating peripheral neuropathies
CN105744937A (zh) * 2013-09-25 2016-07-06 范安德尔研究所 高效糖皮质激素
SG11201903209TA (en) * 2016-10-14 2019-05-30 Van Andel Res Institute Structures and mechanism for the design of highly potent glucocorticoids

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WO1994025478A1 (en) 1993-04-29 1994-11-10 Instytut Farmaceutyczny 16α,17α-ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES
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WO2007054974A2 (en) 2005-09-28 2007-05-18 Arch Pharmalab Limited A green chemistry process for the preparation of pregnadiene esters
KR20100087147A (ko) 2007-10-04 2010-08-03 아스트라제네카 아베 글루코코르티코이드 활성을 갖는 스테로이드성 [3,2-ｃ]피라졸 화합물
JP2011507836A (ja) 2007-12-20 2011-03-10 アストラゼネカ・アクチエボラーグ グルココルチコステロイド受容体アゴニストとして作用するステロイド誘導体
CN102015750A (zh) 2008-02-27 2011-04-13 阿斯利康(瑞典)有限公司 16α,17β-缩醛糖皮质激素衍生物及其用途
UY32525A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32521A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
UY32520A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32523A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides

Also Published As

Publication number Publication date
IL204611A0 (en) 2010-11-30
AU2008306593B2 (en) 2012-04-12
EA201000436A1 (ru) 2010-10-29
AU2008306593C1 (en) 2012-10-04
CO6270214A2 (es) 2011-04-20
WO2009044200A1 (en) 2009-04-09
TW200918047A (en) 2009-05-01
UY31375A1 (es) 2009-05-29
AU2008306593A1 (en) 2009-04-09
US20120178726A1 (en) 2012-07-12
NI201000043A (es) 2012-09-10
CA2700181A1 (en) 2009-04-09
ZA201002223B (en) 2010-12-29
CN101883778A (zh) 2010-11-10
KR20100087147A (ko) 2010-08-03
CL2008002954A1 (es) 2010-01-15
NZ584160A (en) 2011-05-27
MX2010003698A (es) 2010-04-21
DOP2010000094A (es) 2012-08-15
US8163724B2 (en) 2012-04-24
AR068734A1 (es) 2009-12-02
CR11345A (es) 2010-07-15
PE20090776A1 (es) 2009-07-23
US20090286835A1 (en) 2009-11-19
EP2207788A1 (en) 2010-07-21
JP2010540612A (ja) 2010-12-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.