IL204611A0 - Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity - Google Patents

Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity

Info

Publication number
IL204611A0
IL204611A0 IL204611A IL20461110A IL204611A0 IL 204611 A0 IL204611 A0 IL 204611A0 IL 204611 A IL204611 A IL 204611A IL 20461110 A IL20461110 A IL 20461110A IL 204611 A0 IL204611 A0 IL 204611A0
Authority
IL
Israel
Prior art keywords
steroidal
pyrazole compounds
glucocorticoid activity
glucocorticoid
activity
Prior art date
Application number
IL204611A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Svetlana Ivanova
Hakan Bladh
Frank Burkamp
Balint Gabos
Peter Hansen
Karolina Lawitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40328402&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL204611(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab, Svetlana Ivanova, Hakan Bladh, Frank Burkamp, Balint Gabos, Peter Hansen, Karolina Lawitz filed Critical Astrazeneca Ab
Publication of IL204611A0 publication Critical patent/IL204611A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL204611A 2007-10-04 2010-03-18 Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity IL204611A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97741607P 2007-10-04 2007-10-04
PCT/GB2008/050890 WO2009044200A1 (en) 2007-10-04 2008-10-02 Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity

Publications (1)

Publication Number Publication Date
IL204611A0 true IL204611A0 (en) 2010-11-30

Family

ID=40328402

Family Applications (1)

Application Number Title Priority Date Filing Date
IL204611A IL204611A0 (en) 2007-10-04 2010-03-18 Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity

Country Status (23)

Country Link
US (2) US8163724B2 (https=)
EP (1) EP2207788A1 (https=)
JP (1) JP2010540612A (https=)
KR (1) KR20100087147A (https=)
CN (1) CN101883778A (https=)
AR (1) AR068734A1 (https=)
AU (1) AU2008306593C1 (https=)
BR (1) BRPI0817941A2 (https=)
CA (1) CA2700181A1 (https=)
CL (1) CL2008002954A1 (https=)
CO (1) CO6270214A2 (https=)
CR (1) CR11345A (https=)
DO (1) DOP2010000094A (https=)
EA (1) EA201000436A1 (https=)
IL (1) IL204611A0 (https=)
MX (1) MX2010003698A (https=)
NI (1) NI201000043A (https=)
NZ (1) NZ584160A (https=)
PE (1) PE20090776A1 (https=)
TW (1) TW200918047A (https=)
UY (1) UY31375A1 (https=)
WO (1) WO2009044200A1 (https=)
ZA (1) ZA201002223B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201000436A1 (ru) 2007-10-04 2010-10-29 Астразенека Аб Стероидные [3,2-с]пиразольные соединения, обладающие глюкокортикоидной активностью
JP2011507836A (ja) * 2007-12-20 2011-03-10 アストラゼネカ・アクチエボラーグ グルココルチコステロイド受容体アゴニストとして作用するステロイド誘導体
UY32523A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32520A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32525A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32521A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
CN102834406A (zh) * 2009-06-16 2012-12-19 默沙东公司 作为糖皮质激素受体激动剂的新的[3.2-c]杂芳基甾体、其组合物和用途
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
CA2802294C (en) 2010-06-11 2016-05-10 Rhodes Technologies Process for n-dealkylation of tertiary amines
GB201016912D0 (en) * 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
US8829024B2 (en) * 2011-01-07 2014-09-09 Corcept Therapeutics, Inc. Combination steroid and glucocorticoid receptor antagonist therapy
CN103502221B (zh) 2011-03-18 2016-03-30 拜耳知识产权有限责任公司 N-(3-氨甲酰基苯基)-1h-吡唑-5-甲酰胺衍生物及其用于防治动物害虫的用途
US9526729B2 (en) * 2013-01-29 2016-12-27 Hsiao Lily Yu Medicament for treating peripheral neuropathies
JP2016531852A (ja) * 2013-09-25 2016-10-13 ヴァン アンデル リサーチ インスティテュート 非常に強力なグルココルチコイド
EP3525870B1 (en) * 2016-10-14 2023-05-10 Van Andel Research Institute Highly potent glucocorticoids

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JPS6067495A (ja) 1983-09-22 1985-04-17 Ota Seiyaku Kk ピラゾール誘導体
SE8306370D0 (sv) 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
WO1994025478A1 (en) 1993-04-29 1994-11-10 Instytut Farmaceutyczny 16α,17α-ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES
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GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
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KR100831534B1 (ko) * 2001-04-30 2008-05-22 글락소 그룹 리미티드 17.알파 위치에 시클릭 에스테르기를 지닌 항염증성의안드로스탄의 17.베타.-카르보티오에이트 에스테르 유도체
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GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
WO2007054974A2 (en) 2005-09-28 2007-05-18 Arch Pharmalab Limited A green chemistry process for the preparation of pregnadiene esters
EA201000436A1 (ru) 2007-10-04 2010-10-29 Астразенека Аб Стероидные [3,2-с]пиразольные соединения, обладающие глюкокортикоидной активностью
JP2011507836A (ja) 2007-12-20 2011-03-10 アストラゼネカ・アクチエボラーグ グルココルチコステロイド受容体アゴニストとして作用するステロイド誘導体
WO2009108118A1 (en) 2008-02-27 2009-09-03 Astrazeneca Ab 16 alpha, 17 alpa-acetal glucocorticosteroidal derivatives and their use
UY32523A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32520A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32521A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
UY32525A (es) 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides

Also Published As

Publication number Publication date
US8163724B2 (en) 2012-04-24
MX2010003698A (es) 2010-04-21
CO6270214A2 (es) 2011-04-20
PE20090776A1 (es) 2009-07-23
EP2207788A1 (en) 2010-07-21
EA201000436A1 (ru) 2010-10-29
AU2008306593A1 (en) 2009-04-09
BRPI0817941A2 (pt) 2015-05-05
NI201000043A (es) 2012-09-10
UY31375A1 (es) 2009-05-29
CL2008002954A1 (es) 2010-01-15
AR068734A1 (es) 2009-12-02
KR20100087147A (ko) 2010-08-03
US20090286835A1 (en) 2009-11-19
CN101883778A (zh) 2010-11-10
AU2008306593B2 (en) 2012-04-12
CR11345A (es) 2010-07-15
NZ584160A (en) 2011-05-27
DOP2010000094A (es) 2012-08-15
TW200918047A (en) 2009-05-01
ZA201002223B (en) 2010-12-29
WO2009044200A1 (en) 2009-04-09
US20120178726A1 (en) 2012-07-12
CA2700181A1 (en) 2009-04-09
JP2010540612A (ja) 2010-12-24
AU2008306593C1 (en) 2012-10-04

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