BRPI0807222A2 - Análogos de neucleosídeo para tratamento de infecções virais - Google Patents

Análogos de neucleosídeo para tratamento de infecções virais

Info

Publication number
BRPI0807222A2
BRPI0807222A2 BRPI0807222-1A2A BRPI0807222A BRPI0807222A2 BR PI0807222 A2 BRPI0807222 A2 BR PI0807222A2 BR PI0807222 A BRPI0807222 A BR PI0807222A BR PI0807222 A2 BRPI0807222 A2 BR PI0807222A2
Authority
BR
Brazil
Prior art keywords
treatment
viral infections
nucleoside analogs
nucleoside
analogs
Prior art date
Application number
BRPI0807222-1A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Zheng Yin
Jeyaraj Duraiswamy
Yen Liang Chen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39462074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0807222(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0807222A2 publication Critical patent/BRPI0807222A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0807222-1A2A 2007-02-09 2008-02-07 Análogos de neucleosídeo para tratamento de infecções virais BRPI0807222A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07102027 2007-02-09
EP08150003 2008-01-02
PCT/EP2008/051527 WO2008095993A1 (en) 2007-02-09 2008-02-07 Novel nucleoside analogs for treatment of viral infections

Publications (1)

Publication Number Publication Date
BRPI0807222A2 true BRPI0807222A2 (pt) 2014-04-29

Family

ID=39462074

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807222-1A2A BRPI0807222A2 (pt) 2007-02-09 2008-02-07 Análogos de neucleosídeo para tratamento de infecções virais

Country Status (18)

Country Link
US (1) US8278282B2 (enExample)
EP (1) EP2132216B1 (enExample)
JP (1) JP2010518047A (enExample)
KR (1) KR20090109102A (enExample)
CN (1) CN101600726B (enExample)
AR (1) AR065249A1 (enExample)
AT (1) ATE533774T1 (enExample)
AU (1) AU2008212752A1 (enExample)
BR (1) BRPI0807222A2 (enExample)
CA (1) CA2675462A1 (enExample)
CL (1) CL2008000409A1 (enExample)
EA (1) EA200901080A1 (enExample)
ES (1) ES2381093T3 (enExample)
MX (1) MX2009008495A (enExample)
PE (1) PE20090070A1 (enExample)
PT (1) PT2132216E (enExample)
TW (1) TW200838550A (enExample)
WO (1) WO2008095993A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010015643A1 (en) * 2008-08-06 2010-02-11 Novartis Ag New antiviral modified nucleosides
CN102526087B (zh) * 2010-12-30 2014-09-03 南开大学 核苷类化合物在制备治疗肠病毒71(ev71)感染疾病药物的应用
CN105669783B (zh) * 2014-12-03 2019-11-12 广东东阳光药业有限公司 一种制备呋喃糖的方法
KR102630013B1 (ko) 2015-08-06 2024-01-25 키메릭스 인크. 항바이러스제로서 유용한 피롤로피리미딘 뉴클레오시드 및 그의 유사체
KR102185996B1 (ko) 2015-09-23 2020-12-02 머크 샤프 앤드 돔 코포레이션 4'-치환된 뉴클레오시드 리버스 트랜스크립타제 억제제 및 그의 제조법
EA201892448A1 (ru) * 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
TW201815821A (zh) * 2016-07-18 2018-05-01 美商再生元醫藥公司 抗茲卡病毒抗體及使用方法
MA45925A (fr) * 2016-08-12 2019-06-19 Janssen Biopharma Inc Nucléosides et nucléotides substitués et leurs analogues
US11111264B2 (en) 2017-09-21 2021-09-07 Chimerix, Inc. Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof
WO2020219447A1 (en) 2019-04-23 2020-10-29 Elementis Specialties, Inc. Slurry compositions containing mixed branched alkyl organoclay compositions
JP2024545703A (ja) * 2021-12-22 2024-12-10 シージェイ チェルジェダン コーポレイション 核酸由来ヌクレオシドアナログおよびこれらの薬学的に許容可能な塩を含む抗ウイルス用組成物
WO2024012568A1 (en) * 2022-07-15 2024-01-18 Sunshine Lake Pharma Co., Ltd. A key intermediate for preparing glucopyranosyl derivatives and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ3487A1 (fr) * 2001-01-22 2002-07-25 Merck Sharp & Dohme Derives de nucleoside comme inhibiteurs de l'arn polymerase virale d'arn-dependant
JP2005511764A (ja) 2001-12-14 2005-04-28 アルコン，インコーポレイテッド 緑内障の処置のためのアミノアルキルベンゾフラン−５−オール化合物
US7323453B2 (en) 2002-02-13 2008-01-29 Merck & Co., Inc. Methods of inhibiting orthopoxvirus replication with nucleoside compounds
US20040063658A1 (en) * 2002-05-06 2004-04-01 Roberts Christopher Don Nucleoside derivatives for treating hepatitis C virus infection
TW200418498A (en) * 2002-09-30 2004-10-01 Genelabs Tech Inc Nucleoside derivatives for treating hepatitis C virus infection
US20040259934A1 (en) 2003-05-01 2004-12-23 Olsen David B. Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
MXPA06004680A (es) * 2003-10-27 2007-04-17 Genelabs Tech Inc Compuestos de nucleosido para el tratamiento de infecciones virales.

Also Published As

Publication number Publication date
EP2132216A1 (en) 2009-12-16
ATE533774T1 (de) 2011-12-15
PE20090070A1 (es) 2009-03-19
CN101600726B (zh) 2013-03-27
KR20090109102A (ko) 2009-10-19
US20100227833A1 (en) 2010-09-09
AR065249A1 (es) 2009-05-27
CL2008000409A1 (es) 2008-08-29
CA2675462A1 (en) 2008-08-14
TW200838550A (en) 2008-10-01
PT2132216E (pt) 2012-02-20
MX2009008495A (es) 2009-08-20
EP2132216B1 (en) 2011-11-16
JP2010518047A (ja) 2010-05-27
US8278282B2 (en) 2012-10-02
EA200901080A1 (ru) 2010-02-26
WO2008095993A1 (en) 2008-08-14
CN101600726A (zh) 2009-12-09
AU2008212752A1 (en) 2008-08-14
ES2381093T3 (es) 2012-05-23

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2308 DE 31/03/2015.