BRPI0718999A2 - Pirazois substituídos, composições que os contêm, processo de produção e utilização - Google Patents

Pirazois substituídos, composições que os contêm, processo de produção e utilização

Info

Publication number
BRPI0718999A2
BRPI0718999A2 BRPI0718999-0A2A BRPI0718999A BRPI0718999A2 BR PI0718999 A2 BRPI0718999 A2 BR PI0718999A2 BR PI0718999 A BRPI0718999 A BR PI0718999A BR PI0718999 A2 BRPI0718999 A2 BR PI0718999A2
Authority
BR
Brazil
Prior art keywords
pirazois
replaced
production
compositions containing
use process
Prior art date
Application number
BRPI0718999-0A2A
Other languages
English (en)
Inventor
Kirsten Bjergarde
Mark Dodson
Jacques Mauger
Anil Nair
Marcel Patek
Michel Tabart
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0718999A2 publication Critical patent/BRPI0718999A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
BRPI0718999-0A2A 2006-11-10 2007-11-09 Pirazois substituídos, composições que os contêm, processo de produção e utilização BRPI0718999A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0609812A FR2908409B1 (fr) 2006-11-10 2006-11-10 Pyrazoles substituees,compositions les contenant,procede de fabrication et utilisation
PCT/FR2007/001851 WO2008065282A2 (fr) 2006-11-10 2007-11-09 Pyrazoles substituees, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
BRPI0718999A2 true BRPI0718999A2 (pt) 2014-02-25

Family

ID=38169388

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718999-0A2A BRPI0718999A2 (pt) 2006-11-10 2007-11-09 Pirazois substituídos, composições que os contêm, processo de produção e utilização

Country Status (40)

Country Link
US (3) US7989439B2 (pt)
EP (1) EP2091920B1 (pt)
JP (1) JP5538893B2 (pt)
KR (1) KR20090083456A (pt)
CN (1) CN101553473B (pt)
AR (1) AR063638A1 (pt)
AU (1) AU2007327423B2 (pt)
BR (1) BRPI0718999A2 (pt)
CA (1) CA2667846A1 (pt)
CL (1) CL2007003251A1 (pt)
CO (1) CO6190516A2 (pt)
CR (1) CR10749A (pt)
CY (1) CY1116000T1 (pt)
DK (1) DK2091920T3 (pt)
DO (1) DOP2009000088A (pt)
EA (1) EA019454B1 (pt)
EC (1) ECSP099312A (pt)
ES (1) ES2528385T3 (pt)
FR (1) FR2908409B1 (pt)
HK (1) HK1137988A1 (pt)
HN (1) HN2009000856A (pt)
HR (1) HRP20150070T1 (pt)
IL (1) IL198328A0 (pt)
MA (1) MA30972B1 (pt)
MX (1) MX2009004983A (pt)
MY (1) MY147502A (pt)
NI (1) NI200900078A (pt)
NO (1) NO20091990L (pt)
NZ (1) NZ576709A (pt)
PE (2) PE20121152A1 (pt)
PL (1) PL2091920T3 (pt)
PT (1) PT2091920E (pt)
SI (1) SI2091920T1 (pt)
SV (1) SV2009003253A (pt)
TN (1) TN2009000155A1 (pt)
TW (1) TW200829556A (pt)
UA (1) UA97965C2 (pt)
UY (1) UY30707A1 (pt)
WO (1) WO2008065282A2 (pt)
ZA (1) ZA200903560B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7858323B2 (en) * 2004-06-09 2010-12-28 The Regents Of The University Of Michigan Phage microarray profiling of the humoral response to disease
FR2947546B1 (fr) * 2009-07-03 2011-07-01 Sanofi Aventis Derives de pyrazoles, leur preparation et leur application en therapeutique
UY33200A (es) * 2010-01-26 2011-08-31 Sanofi Aventis Derivados de ácido 3-heteroaroilamino-propiónico sustituidos con oxígeno y su uso como productos farmacéuticos
TWI523844B (zh) 2011-01-26 2016-03-01 賽諾菲公司 經胺基取代之３－雜芳醯基胺基－丙酸衍生物及其作為藥物之用途
CN102432639B (zh) * 2011-09-30 2013-11-06 山东大学 1-(2-羟基-3-(苯氨基)丙基)-3-二茂铁基-1h-吡唑-5-甲酸乙酯化合物及其应用
EA201500393A1 (ru) 2012-11-02 2016-05-31 Пфайзер Инк. Ингибиторы тирозинкиназы брутона
BR112017016817A2 (pt) * 2015-03-25 2018-04-03 Novartis Ag derivados heterocíclicos formilados como inibidores de fgfr4
CN107619388A (zh) * 2016-07-13 2018-01-23 南京天印健华医药科技有限公司 作为fgfr抑制剂的杂环化合物
CN107840842A (zh) 2016-09-19 2018-03-27 北京天诚医药科技有限公司 炔代杂环化合物、其制备方法及其在医药学上的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878714B2 (en) * 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
WO2002088090A2 (en) * 2001-04-27 2002-11-07 Vertex Pharmaceuticals Incorporated Pyrazole derived kinase inhibitors
CA2522079A1 (en) * 2003-04-16 2004-11-04 Astrazeneca Ab Quinazoline derivatives for treatment of cancer
US20040220186A1 (en) * 2003-04-30 2004-11-04 Pfizer Inc. PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
KR101204247B1 (ko) * 2003-07-22 2012-11-22 아스텍스 테라퓨틱스 리미티드 3,4-이치환된 1ｈ-피라졸 화합물 및 그의 시클린 의존성키나제 (ｃｄｋ) 및 글리코겐 합성효소 키나제-3(ｇｓｋ-3) 조정제로서 용도
WO2006003440A1 (en) * 2004-07-05 2006-01-12 Astex Therapeutics Limited 3,4-disubstituted pyrazoles as cyclin dependent kinases (cdk) or aurora kinase or glycogen synthase 3 (gsk-3) inhibitors
US20080261952A1 (en) * 2004-08-16 2008-10-23 Jason Bloxham Aryl Urea Derivatives for Treating Obesity
US20100160324A1 (en) * 2004-12-30 2010-06-24 Astex Therapeutics Limited Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases
JP2008528469A (ja) * 2005-01-21 2008-07-31 アステックス・セラピューティクス・リミテッド ピラゾールキナーゼ阻害剤およびさらなる抗癌剤の組合せ剤
AR052559A1 (es) * 2005-01-21 2007-03-21 Astex Therapeutics Ltd Derivados de pirazol para inhibir cdk's y gsk's
EP1683796A1 (en) * 2005-01-24 2006-07-26 Schering Aktiengesellschaft Pyrazolopyridines, their preparation and their medical use
FR2947546B1 (fr) * 2009-07-03 2011-07-01 Sanofi Aventis Derives de pyrazoles, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
EA019454B1 (ru) 2014-03-31
EP2091920A2 (fr) 2009-08-26
US20110237641A1 (en) 2011-09-29
KR20090083456A (ko) 2009-08-03
PL2091920T3 (pl) 2015-04-30
MA30972B1 (fr) 2009-12-01
NO20091990L (no) 2009-06-02
CY1116000T1 (el) 2017-01-25
WO2008065282A2 (fr) 2008-06-05
TN2009000155A1 (fr) 2010-10-18
NZ576709A (en) 2011-08-26
AU2007327423A1 (en) 2008-06-05
NI200900078A (es) 2010-01-27
CA2667846A1 (fr) 2008-06-05
UA97965C2 (ru) 2012-04-10
FR2908409B1 (fr) 2009-01-09
CR10749A (es) 2009-07-23
PE20081162A1 (es) 2008-10-02
ZA200903560B (en) 2010-08-25
JP5538893B2 (ja) 2014-07-02
MX2009004983A (es) 2009-05-22
FR2908409A1 (fr) 2008-05-16
DOP2009000088A (es) 2013-06-15
JP2010509297A (ja) 2010-03-25
ECSP099312A (es) 2009-06-30
IL198328A0 (en) 2010-02-17
HK1137988A1 (en) 2010-08-13
AU2007327423B2 (en) 2012-09-06
CL2007003251A1 (es) 2009-08-07
UY30707A1 (es) 2008-07-03
PT2091920E (pt) 2015-02-05
EA200970472A1 (ru) 2009-10-30
PE20121152A1 (es) 2012-09-07
TW200829556A (en) 2008-07-16
ES2528385T3 (es) 2015-02-09
WO2008065282A3 (fr) 2008-07-31
HRP20150070T1 (hr) 2015-02-27
CO6190516A2 (es) 2010-08-19
AR063638A1 (es) 2009-02-04
SI2091920T1 (sl) 2015-02-27
MY147502A (en) 2012-12-14
SV2009003253A (es) 2009-10-27
HN2009000856A (es) 2011-10-19
US7989439B2 (en) 2011-08-02
CN101553473A (zh) 2009-10-07
EP2091920B1 (fr) 2014-10-22
US8420824B2 (en) 2013-04-16
US20110237801A1 (en) 2011-09-29
US20090291984A1 (en) 2009-11-26
DK2091920T3 (en) 2015-01-26
US8410286B2 (en) 2013-04-02
CN101553473B (zh) 2013-06-05

Similar Documents

Publication Publication Date Title
BRPI0718440A2 (pt) Processo de preparo de halogenetos de n-alquinaltrexona
BRPI0716479A2 (pt) Processo sol-gel
BRPI0718999A2 (pt) Pirazois substituídos, composições que os contêm, processo de produção e utilização
BRPI0821801A2 (pt) Zeólito e processo de preparação de um zeólito.
BRPI0718339A2 (pt) Composto, composição, composição farmacêutica e processo de fabricação de tanato de rasagilina
BRPI0720068A2 (pt) Processo para preparar nanocápsulas, produto, nanocápsulas e composição
BRPI0821944A2 (pt) Processo
BRPI0906249A2 (pt) Processo de elaboração de 1,1,1,4,4,4-hexafluoro-2-buteno
BRPI0919868A2 (pt) processo
BR112012000821A2 (pt) "processo"
BRPI0718075A2 (pt) Processo de hidrogenação
BR112012005321A2 (pt) processo e composição
BRPI0717897A2 (pt) Processo para produção de ácido acrílico, aparelho para produção de ácido acrílico e composição para produção de ácido acrílico
BRPI0716703A2 (pt) "composiÇço, fluidos funcionais e processo de preparaÇço de uma composiÇço"
BRPI0806897A2 (pt) Processo de obtenção de trans-resveratrol e/ou emodina e composições nutracêuticas contendo os mesmos
BRPI0921374A2 (pt) processo
BRPI0914221A2 (pt) processo, e, composto
BRPI0806679A2 (pt) Processo aperfeiçoado de produção de alquilaromático
BRPI0815126A2 (pt) Processo de síntese do (7-metóxi-l-naftil) acetonitrila e aplicação à síntese da agomelatina
ITMI20060082A1 (it) Processo per la preparazione di biodiesel
BRPI0813438A2 (pt) Processo para preparar um composto, uso de um composto, e, composto.
BRPI0816237A2 (pt) Processo de ciclopropanação
BR112012004668A2 (pt) "composição e processo"
BRPI0810560A2 (pt) Composição de bebida, processo para produzir uma composição de bebida, e, uso de uma composição de bebida.
BRPI0822066A2 (pt) derivados diolatos daizênio, o respectivo processo de preparo e as composições farmacêuticas que os contêm

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.