BRPI0717084A2 - Formulação efervescente de ibuprofeno com alta taxa de dissolução e processo para a sua preparação - Google Patents

Formulação efervescente de ibuprofeno com alta taxa de dissolução e processo para a sua preparação

Info

Publication number
BRPI0717084A2
BRPI0717084A2 BRPI0717084-0A2A BRPI0717084A BRPI0717084A2 BR PI0717084 A2 BRPI0717084 A2 BR PI0717084A2 BR PI0717084 A BRPI0717084 A BR PI0717084A BR PI0717084 A2 BRPI0717084 A2 BR PI0717084A2
Authority
BR
Brazil
Prior art keywords
effersive
ibuprophen
formulation
preparation
dissolution rate
Prior art date
Application number
BRPI0717084-0A2A
Other languages
English (en)
Inventor
Peter Gruber
Hubert Keck
Original Assignee
Losan Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Losan Pharma Gmbh filed Critical Losan Pharma Gmbh
Publication of BRPI0717084A2 publication Critical patent/BRPI0717084A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
BRPI0717084-0A2A 2006-09-26 2007-08-30 Formulação efervescente de ibuprofeno com alta taxa de dissolução e processo para a sua preparação BRPI0717084A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121278A EP1905428A1 (de) 2006-09-26 2006-09-26 Ibuprofen-Brausezubereitung mit hoher Lösungsgeschwindigkeit und Verfahren zu deren Herstellung
PCT/EP2007/059043 WO2008037555A1 (de) 2006-09-26 2007-08-30 Ibuprofen-brausezuberξitung mit hoher lösungsgeschwindigkeit und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BRPI0717084A2 true BRPI0717084A2 (pt) 2013-10-29

Family

ID=37775689

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0717084-0A2A BRPI0717084A2 (pt) 2006-09-26 2007-08-30 Formulação efervescente de ibuprofeno com alta taxa de dissolução e processo para a sua preparação

Country Status (22)

Country Link
US (1) US20100172981A1 (pt)
EP (2) EP1905428A1 (pt)
JP (1) JP2010504366A (pt)
KR (1) KR20090074784A (pt)
CN (1) CN101534797B (pt)
AT (1) ATE438387T1 (pt)
AU (1) AU2007302161A1 (pt)
BR (1) BRPI0717084A2 (pt)
CA (1) CA2664420A1 (pt)
CO (1) CO6180421A2 (pt)
DE (1) DE502007001262D1 (pt)
DK (1) DK2061436T3 (pt)
EC (1) ECSP099200A (pt)
ES (1) ES2331438T3 (pt)
IL (1) IL197309A0 (pt)
MX (1) MX2009003065A (pt)
NZ (1) NZ575183A (pt)
PL (1) PL2061436T3 (pt)
PT (1) PT2061436E (pt)
RU (1) RU2478381C2 (pt)
WO (1) WO2008037555A1 (pt)
ZA (1) ZA200901478B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2602392A1 (en) 2005-03-22 2006-09-28 Losan Pharma Gmbh Solubilized ibuprofen
KR101683293B1 (ko) * 2009-06-29 2016-12-06 라이온 가부시키가이샤 경구용 조성물
JP5663238B2 (ja) * 2009-08-31 2015-02-04 ライオン株式会社 内服固形製剤及びその製造方法
CN102100686A (zh) * 2009-12-21 2011-06-22 北京润德康医药技术有限公司 一种含有布洛芬与精氨酸的药用组合物及其制备方法、用途
CN102743366B (zh) * 2012-07-16 2013-11-20 海南葫芦娃制药有限公司 对乙酰氨基酚泡腾颗粒及其鉴别方法
CA3018828C (en) 2014-09-17 2021-05-11 Steerlife India Private Limited Effervescent composition and method of making it
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
FR3055800B1 (fr) 2016-09-15 2020-06-26 Unither Pharmaceuticals Composition solide a ingestion rapide et deglutition facilitee, sous forme de particules solides non agglomerees, comprenant deux differents types de particules
JP6836375B2 (ja) * 2016-11-21 2021-03-03 花王株式会社 口腔内発泡製剤及びその製造法
GB2595453B (en) * 2020-05-21 2024-04-03 Reckitt Benckiser Health Ltd Novel Formulation
GB2595300B (en) * 2020-05-21 2024-03-27 Reckitt Benckiser Health Ltd Novel Formulation
GB2595301A (en) * 2020-05-21 2021-11-24 Reckitt Benckiser Health Ltd Novel formulation
US20230292992A1 (en) * 2022-03-18 2023-09-21 CapsoVision, Inc. Apparatus for Thermally Stable Capsule Endoscope Using Effervescent Formulation for Controlling Balloon Inflation Rate
WO2023182904A1 (ru) * 2022-03-21 2023-09-28 Акционерное Общество "Производственная Фармацевтическая Компания Обновление" Шипучий лекарственный препарат для приготовления раствора, способ его изготовления

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
CH677606A5 (pt) * 1988-07-12 1991-06-14 Aesculapius Pharma Sa
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
CH684929A5 (de) * 1992-11-19 1995-02-15 Sipharm Sisseln Ag Ibuprofen-haltige Brausezusammensetzung und ihre Herstellung.
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
GB9816899D0 (en) * 1998-08-05 1998-09-30 Boots Co Plc Therapeutic agents
ATE534371T1 (de) * 2003-02-06 2011-12-15 Gebro Pharma Gmbh Pharmazeutische zubereitungen und verfahren zu deren herstellung
WO2006002836A1 (de) * 2004-07-01 2006-01-12 Losan Pharma Gmbh Brausezusammensetzungen von einschlafmitteln
CA2602392A1 (en) * 2005-03-22 2006-09-28 Losan Pharma Gmbh Solubilized ibuprofen
EP1886423A1 (en) 2005-05-12 2008-02-13 Perlos Oyj Optical signal processing device

Also Published As

Publication number Publication date
WO2008037555A1 (de) 2008-04-03
CA2664420A1 (en) 2008-04-03
MX2009003065A (es) 2009-05-28
ES2331438T3 (es) 2010-01-04
CN101534797B (zh) 2012-03-28
JP2010504366A (ja) 2010-02-12
ATE438387T1 (de) 2009-08-15
AU2007302161A1 (en) 2008-04-03
NZ575183A (en) 2012-03-30
PT2061436E (pt) 2009-10-30
EP1905428A1 (de) 2008-04-02
RU2478381C2 (ru) 2013-04-10
IL197309A0 (en) 2009-12-24
ZA200901478B (en) 2010-03-31
DE502007001262D1 (de) 2009-09-17
RU2009107536A (ru) 2010-11-20
KR20090074784A (ko) 2009-07-07
EP2061436A1 (de) 2009-05-27
CO6180421A2 (es) 2010-07-19
US20100172981A1 (en) 2010-07-08
EP2061436B1 (de) 2009-08-05
CN101534797A (zh) 2009-09-16
DK2061436T3 (da) 2009-11-02
ECSP099200A (es) 2009-06-30
PL2061436T3 (pl) 2009-12-31

Similar Documents

Publication Publication Date Title
BRPI0717084A2 (pt) Formulação efervescente de ibuprofeno com alta taxa de dissolução e processo para a sua preparação
Bonabello et al. Dexibuprofen (S (+)-isomer ibuprofen) reduces gastric damage and improves analgesic and antiinflammatory effects in rodents
EA200702552A1 (ru) Непрерывный способ получения хлоргидринов
MX2009004203A (es) Combinaciones de paracetamol/ibuprofeno y metodo para su uso.
MX2009013255A (es) Matriz de solidificacion que incluye una sal de un acido mono-, di- o tri-carboxilico saturado de cadena recta.
DK2264043T3 (da) Heterobifunktionelle pan-selektin-inhibitorer
WO2007005633A8 (en) Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate
NZ590288A (en) Topical composition for the treatment of actinic keratosis containing less than 5 per cent water
JP2006515358A5 (pt)
SG149080A1 (en) Composition comprising a nsaid and paracetamol
EA200702072A1 (ru) Фенилсодержащие n-ацильные производные аминов и аминокислот, способ их получения, фармацевтическая композиция и их применение
ATE474556T1 (de) Galenische form zur transmukosalen verabreichung von paracetamol
WO2007120725A3 (en) Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive
TNSN07228A1 (en) Manufacture process of organic compounds
DK1765770T3 (da) Fremgangsmåde til fremstilling af gabapentin
BRPI0509923A (pt) processo para formação de cálcio de atorvastatina amorfa
AR056469A1 (es) Ibuprofeno solubilizado
BR112013006404A2 (pt) processo para produzir grânulos, formulação, e, usos dos grânulos e dos aglomerados prensados
AR047461A1 (es) Formacion, purificacion y uso de n-formilolanzapina
UA94042C2 (ru) Применение агомелатина в получении лекарственных средств, предназначенных для лечения синдрома смита-магениса
RS51659B (en) THE USE OF AGOMELATIN FOR OBTAINING MEDICINES FOR THE TREATMENT OF BIPOLAR DISORDERS
TW200514571A (en) Pharmaceutical composition with improved solubility and fluidity
WO2004093867A3 (en) Phenolic acid salts of gabapentin in liquid and/or semi-solid dosage forms and methods of use
WO2008155920A1 (ja) 肝細胞増殖促進作用を有する医薬
FR2956810B1 (fr) Composition cosmetique a base d'acide ellagique ou d'un de ses derives et d'un melange particulier de tensioactifs anioniques et amphoteres ou zwitterioniques.

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2326 DE 04-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.